"Comet Assay" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A genotoxicological technique for measuring DNA damage in an individual cell using single-cell gel electrophoresis. Cell DNA fragments assume a "comet with tail" formation on electrophoresis and are detected with an image analysis system. Alkaline assay conditions facilitate sensitive detection of single-strand damage.
| Descriptor ID |
D020552
|
| MeSH Number(s) |
E05.196.401.153.150 E05.301.300.100.150 E05.393.560.150 E05.940.560.150
|
| Concept/Terms |
Comet Assay- Comet Assay
- Assay, Comet
- Assays, Comet
- Comet Assays
- Gel Electrophoresis, Single-Cell
- Electrophoreses, Single-Cell Gel
- Electrophoresis, Single-Cell Gel
- Gel Electrophoreses, Single-Cell
- Gel Electrophoresis, Single Cell
- Single-Cell Gel Electrophoreses
- Single-Cell Gel Electrophoresis
- Electrophoresis, Gel, Single-Cell
Alkaline Comet Assay- Alkaline Comet Assay
- Alkaline Comet Assays
- Assay, Alkaline Comet
- Assays, Alkaline Comet
- Comet Assay, Alkaline
- Comet Assays, Alkaline
- Alkaline Single-Cell Gel Electrophoresis Assay
- Alkaline Single Cell Gel Electrophoresis Assay
|
Below are MeSH descriptors whose meaning is more general than "Comet Assay".
Below are MeSH descriptors whose meaning is more specific than "Comet Assay".
This graph shows the total number of publications written about "Comet Assay" by people in this website by year, and whether "Comet Assay" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 1 | 2 |
| 2011 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 3 | 3 |
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Below are the most recent publications written about "Comet Assay" by people in Profiles.
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Cytotoxicity and genotoxicity of lipid nanocapsules. Toxicol In Vitro. 2017 Jun; 41:189-199.
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CDK1 Enhances Mitochondrial Bioenergetics for Radiation-Induced DNA Repair. Cell Rep. 2015 Dec 15; 13(10):2056-63.
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Dexrazoxane Diminishes Doxorubicin-Induced Acute Ovarian Damage and Preserves Ovarian Function and Fecundity in Mice. PLoS One. 2015; 10(11):e0142588.
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S-phase-dependent p50/NF-?B1 phosphorylation in response to ATR and replication stress acts to maintain genomic stability. Cell Cycle. 2015; 14(4):566-76.
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Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication. Nat Commun. 2014 Apr 14; 5:3649.
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Chronic inhalation of biomass smoke is associated with DNA damage in airway cells: involvement of particulate pollutants and benzene. J Appl Toxicol. 2013 Apr; 33(4):281-9.
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AMP-activated protein kinase attenuates nitric oxide-induced beta-cell death. J Biol Chem. 2010 Jan 29; 285(5):3191-200.
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Control of the release of freely diffusing molecules in single-cell electroporation. Anal Chem. 2009 Oct 01; 81(19):8001-8.
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Photooxidative action in cancer and normal cells induced by the use of photofrin in photodynamic therapy. Folia Biol (Praha). 2008; 54(1):24-9.
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The influence of photodynamic therapy on apoptosis in human melanoma cell line. Folia Histochem Cytobiol. 2005; 43(3):129-32.