Receptor, Serotonin, 5-HT1B
"Receptor, Serotonin, 5-HT1B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serotonin receptor subtype found at high levels in the BASAL GANGLIA and the frontal cortex. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1D RECEPTOR. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigraine effect.
| Descriptor ID |
D044302
|
| MeSH Number(s) |
D12.776.543.750.670.800.100.150 D12.776.543.750.695.800.100.150 D12.776.543.750.720.670.100.500 D12.776.543.750.720.850.100.150
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| Concept/Terms |
Receptor, Serotonin, 5-HT1B- Receptor, Serotonin, 5-HT1B
- 5-HT1B Receptor
- 5 HT1B Receptor
- Receptor, 5-HT1B
- 5-Hydroxytryptamine 1B Receptor
- 1B Receptor, 5-Hydroxytryptamine
- 5 Hydroxytryptamine 1B Receptor
- 5-Hydroxytryptamine 1B Receptors
- 1B Receptors, 5-Hydroxytryptamine
- 5 Hydroxytryptamine 1B Receptors
- Receptors, 5-Hydroxytryptamine 1B
- Receptor, 5-Hydroxytryptamine 1B
- Receptor, 5 Hydroxytryptamine 1B
- Serotonin 1B Receptor
- Receptor, Serotonin 1B
- 5-HT1Dbeta Receptor
- 5 HT1Dbeta Receptor
- Receptor, 5-HT1Dbeta
- Receptor, Serotonin Type 1Dbeta
- Serotonin 1Dbeta Receptors
- Receptors, Serotonin 1Dbeta
- Serotonin 1Dbeta Receptor
- Receptor, Serotonin 1Dbeta
- Serotonin 1D Beta Receptor
- 5-HT(1B) Receptor
- 5-HT(1Dbeta) Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Serotonin, 5-HT1B".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Serotonin [D12.776.543.750.670.800]
- Receptors, Serotonin, 5-HT1 [D12.776.543.750.670.800.100]
- Receptor, Serotonin, 5-HT1B [D12.776.543.750.670.800.100.150]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Serotonin [D12.776.543.750.695.800]
- Receptors, Serotonin, 5-HT1 [D12.776.543.750.695.800.100]
- Receptor, Serotonin, 5-HT1B [D12.776.543.750.695.800.100.150]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Presynaptic [D12.776.543.750.720.670]
- Autoreceptors [D12.776.543.750.720.670.100]
- Receptor, Serotonin, 5-HT1B [D12.776.543.750.720.670.100.500]
- Receptors, Serotonin [D12.776.543.750.720.850]
- Receptors, Serotonin, 5-HT1 [D12.776.543.750.720.850.100]
- Receptor, Serotonin, 5-HT1B [D12.776.543.750.720.850.100.150]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Serotonin, 5-HT1B".
This graph shows the total number of publications written about "Receptor, Serotonin, 5-HT1B" by people in this website by year, and whether "Receptor, Serotonin, 5-HT1B" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Receptor, Serotonin, 5-HT1B" by people in Profiles.
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Genetic influences on ADHD symptom dimensions: Examination of a priori candidates, gene-based tests, genome-wide variation, and SNP heritability. Am J Med Genet B Neuropsychiatr Genet. 2017 Jun; 174(4):458-466.
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Effects of chronic fluoxetine treatment on serotonin 1B receptor-induced deficits in delayed alternation. Psychopharmacology (Berl). 2013 Jun; 227(3):545-51.
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Essential role for orbitofrontal serotonin 1B receptors in obsessive-compulsive disorder-like behavior and serotonin reuptake inhibitor response in mice. Biol Psychiatry. 2011 Dec 01; 70(11):1039-48.
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Serotonin induces long-term depression at corticostriatal synapses. J Neurosci. 2011 May 18; 31(20):7402-11.
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Chronic reductions in serotonin transporter function prevent 5-HT1B-induced behavioral effects in mice. Biol Psychiatry. 2009 Mar 01; 65(5):401-8.
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Association studies of serotonin system candidate genes in early-onset obsessive-compulsive disorder. Biol Psychiatry. 2007 Feb 01; 61(3):322-9.
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Polymorphisms in the 5'-untranslated region of the human serotonin receptor 1B (HTR1B) gene affect gene expression. Mol Psychiatry. 2003 Nov; 8(11):901-10.
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DNA variation and psychopharmacology of the human serotonin receptor 1B (HTR1B) gene. Pharmacogenomics. 2002 Nov; 3(6):745-62.
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Genetic diversity of the human serotonin receptor 1B (HTR1B) gene. Genomics. 2001 Feb 15; 72(1):1-14.
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Knockout mice reveal opposite roles for serotonin 1A and 1B receptors in prepulse inhibition. Neuropsychopharmacology. 2000 Jun; 22(6):650-9.