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Jasmine Nirody

TitleAssistant Professor
InstitutionUniversity of Chicago
DepartmentOrganismal Biology and Anatomy
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    Natural environments are complex and dynamic, and organisms must be able to sense and respond to constantly changing mechanical stimuli as they move through their surroundings. This can be observed across levels of biological organization: proteins remodel themselves in response to external stresses, cells adapt their movement in response to changes in media or substrate, animals vary their stepping patterns with walking speed and type of terrain. I'm interested in the relationship between structure and function in such adaptable systems moving through variable environments.

    While the underlying mechanisms may vary as we shift our focus from molecular motors to bacteria to animals, the larger questions remain the same:

    - How do biological systems sense and respond to mechanical stresses in complex environments?
    - What performance tradeoffs does adaptability/flexibility pose for biomechanical systems?
    - How do flexible locomotive strategies affect the evolution of structure in locomotor systems?

    We use both theory and experiment (laboratory + field) to answer these questions and are excited to work with techniques from biomechanics, biophysics, mechanical engineering, and more. Research in the lab currently centers around two broadly defined organismal systems: flagellated bacteria and walking panarthropods, but we are fascinated by a huge range of questions and organisms.

    For more details on past and ongoing projects in the lab, check out our website (http://nirodylab.uchicago.edu) or get in touch to chat!

    Collapse Biography 
    Collapse education and training
    Rockefeller University, New YorkFellowPhysics and Biology
    All Souls College, University of Oxford, Oxford, UKFellowPhysics and Zoology
    University of California, Berkeley, Berkeley, CAPhD2017Biophysics
    New York University, New York, NYBA2008Mathematics and Biology

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dayton H, Kiss J, Wei M, Chauhan S, LaMarre E, Cornell WC, Morgan CJ, Janakiraman A, Min W, Tomer R, Price-Whelan A, Nirody JA, Dietrich LEP. Cellular arrangement impacts metabolic activity and antibiotic tolerance in Pseudomonas aeruginosa biofilms. PLoS Biol. 2024 Feb; 22(2):e3002205. PMID: 38300958; PMCID: PMC10833521.
      Citations:    Fields:    Translation:HumansCells
    2. Dayton H, Kiss J, Wei M, Chauhan S, LaMarre E, Cornell WC, Morgan CJ, Janakiraman A, Min W, Tomer R, Price-Whelan A, Nirody JA, Dietrich LEP. Cell arrangement impacts metabolic activity and antibiotic tolerance in Pseudomonas aeruginosa biofilms. bioRxiv. 2023 Aug 28. PMID: 37645902; PMCID: PMC10462148.
      Citations:    
    3. Nirody JA. Flexible locomotion in complex environments: the influence of species, speed and sensory feedback on panarthropod inter-leg coordination. J Exp Biol. 2023 04 25; 226(Suppl_1). PMID: 36912384.
      Citations:    Fields:    Translation:Animals
    4. Nirody JA. Universal Features in Panarthropod Inter-Limb Coordination during Forward Walking. Integr Comp Biol. 2021 09 08; 61(2):710-722. PMID: 34043783; PMCID: PMC8427173.
      Citations: 3     Fields:    Translation:Animals
    5. Nirody JA, Duran LA, Johnston D, Cohen DJ. Tardigrades exhibit robust interlimb coordination across walking speeds and terrains. Proc Natl Acad Sci U S A. 2021 08 31; 118(35). PMID: 34446560; PMCID: PMC8536314.
      Citations: 7     Fields:    Translation:Animals
    6. Nirody JA, Budin I, Rangamani P. ATP synthase: Evolution, energetics, and membrane interactions. J Gen Physiol. 2020 11 02; 152(11). PMID: 32966553; PMCID: PMC7594442.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    7. Nirody JA, Berry RM, Nord AL. Load-dependent adaptation near zero load in the bacterial flagellar motor. J R Soc Interface. 2019 10 31; 16(159):20190300. PMID: 31575345; PMCID: PMC6833329.
      Citations: 9     Fields:    Translation:Cells
    8. Igoshin OA, Chen J, Xing J, Liu J, Elston TC, Grabe M, Kim KS, Nirody JA, Rangamani P, Sun SX, Wang H, Wolgemuth C. Biophysics at the coffee shop: lessons learned working with George Oster. Mol Biol Cell. 2019 07 22; 30(16):1882-1889. PMID: 31322997; PMCID: PMC6727762.
      Citations: 3     Fields:    Translation:HumansAnimals
    9. Nirody JA, Jinn J, Libby T, Lee TJ, Jusufi A, Hu DL, Full RJ. Geckos Race Across the Water's Surface Using Multiple Mechanisms. Curr Biol. 2018 12 17; 28(24):4046-4051.e2. PMID: 30528580.
      Citations: 8     Fields:    Translation:Animals
    10. Perez-Carrasco R, Nirody JA, Berry RM, Nord AL, Gachon E, Barducci A, Pedaci F. Catch bond drives stator mechanosensitivity in the bacterial flagellar motor. Proc Natl Acad Sci U S A. 2017 12 05; 114(49):12952-12957. PMID: 29183968; PMCID: PMC5724282.
      Citations: 47     Fields:    Translation:Cells
    11. Getz MC, Nirody JA, Rangamani P. Stability analysis in spatial modeling of cell signaling. Wiley Interdiscip Rev Syst Biol Med. 2018 01; 10(1). PMID: 28787545.
      Citations: 2     Fields:    Translation:HumansCells
    12. Nirody JA, Berry RM, Oster G. The Limiting Speed of the Bacterial Flagellar Motor. Biophys J. 2016 Aug 09; 111(3):557-564. PMID: 27508439; PMCID: PMC4982938.
      Citations: 11     Fields:    Translation:Cells
    13. Heilmeier U, Cheng K, Pasco C, Parrish R, Nirody J, Patsch JM, Zhang CA, Joseph GB, Burghardt AJ, Schwartz AV, Link TM, Kazakia G. Cortical bone laminar analysis reveals increased midcortical and periosteal porosity in type 2 diabetic postmenopausal women with history of fragility fractures compared to fracture-free diabetics. Osteoporos Int. 2016 09; 27(9):2791-2802. PMID: 27154435; PMCID: PMC6687459.
      Citations: 26     Fields:    Translation:Humans
    14. Mandadapu KK, Nirody JA, Berry RM, Oster G. Mechanics of torque generation in the bacterial flagellar motor. Proc Natl Acad Sci U S A. 2015 Aug 11; 112(32):E4381-9. PMID: 26216959; PMCID: PMC4538651.
      Citations: 18     Fields:    Translation:Cells
    15. Nirody JA, Cheng KP, Parrish RM, Burghardt AJ, Majumdar S, Link TM, Kazakia GJ. Spatial distribution of intracortical porosity varies across age and sex. Bone. 2015 Jun; 75:88-95. PMID: 25701139; PMCID: PMC4454740.
      Citations: 21     Fields:    Translation:Humans
    16. Lourens MA, Schwab BC, Nirody JA, Meijer HG, van Gils SA. Exploiting pallidal plasticity for stimulation in Parkinson's disease. J Neural Eng. 2015 Apr; 12(2):026005. PMID: 25650741.
      Citations: 16     Fields:    Translation:Humans
    17. Tataru P, Nirody JA, Song YS. diCal-IBD: demography-aware inference of identity-by-descent tracts in unrelated individuals. Bioinformatics. 2014 Dec 01; 30(23):3430-1. PMID: 25147361; PMCID: PMC4296155.
      Citations: 5     Fields:    Translation:Humans
    18. Nirody JA. Development of spatial coarse-to-fine processing in the visual pathway. J Comput Neurosci. 2014 Jun; 36(3):401-14. PMID: 24077933.
      Citations: 1     Fields:    Translation:HumansCells
    19. Kazakia GJ, Tjong W, Nirody JA, Burghardt AJ, Carballido-Gamio J, Patsch JM, Link T, Feeley BT, Ma CB. The influence of disuse on bone microstructure and mechanics assessed by HR-pQCT. Bone. 2014 Jun; 63:132-40. PMID: 24603002; PMCID: PMC4041600.
      Citations: 38     Fields:    Translation:HumansCTClinical Trials
    20. Tjong W, Nirody J, Burghardt AJ, Carballido-Gamio J, Kazakia GJ. Structural analysis of cortical porosity applied to HR-pQCT data. Med Phys. 2014 Jan; 41(1):013701. PMID: 24387533; PMCID: PMC3895089.
      Citations: 17     Fields:    Translation:Humans
    21. Kazakia GJ, Nirody JA, Bernstein G, Sode M, Burghardt AJ, Majumdar S. Age- and gender-related differences in cortical geometry and microstructure: Improved sensitivity by regional analysis. Bone. 2013 Feb; 52(2):623-31. PMID: 23142360; PMCID: PMC3564644.
      Citations: 26     Fields:    Translation:Humans
    22. Serna S, Nirody JA, Rácz MZ. Analysis of unstable behavior in a mathematical model for erythropoiesis. J Math Biol. 2013 Feb; 66(3):595-625. PMID: 22476159.
      Citations:    Fields:    Translation:HumansAnimals
    23. Moore JR, Li X, Nirody J, Fischer S, Lehman W. Structural implications of conserved aspartate residues located in tropomyosin's coiled-coil core. Bioarchitecture. 2011 Sep 01; 1(5):250-255. PMID: 22754618; PMCID: PMC3384579.
      Citations: 13     Fields:    
    24. Hu DL, Nirody J, Scott T, Shelley MJ. The mechanics of slithering locomotion. Proc Natl Acad Sci U S A. 2009 Jun 23; 106(25):10081-5. PMID: 19506255; PMCID: PMC2700932.
      Citations: 48     Fields:    Translation:Animals
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