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Connection

Chuan He to Adenosine

This is a "connection" page, showing publications Chuan He has written about Adenosine.
Connection Strength

25.688
  1. Spatially resolved m6A profiling using m6A-ARTR-DBiT. Nat Methods. 2026 Jul; 23(7):1318-1326.
    View in: PubMed
    Score: 0.753
  2. Small-molecule-catalysed deamination enables transcriptome-wide profiling of N6-methyladenosine in RNA. Nat Chem. 2025 07; 17(7):1042-1052.
    View in: PubMed
    Score: 0.696
  3. Acetylation of METTL3: A negative regulator of m6A deposition on chromatin-associated regulatory RNAs. Mol Cell. 2025 Apr 03; 85(7):1251-1252.
    View in: PubMed
    Score: 0.694
  4. N6-methyladenosine reader YTHDF2 in cell state transition and antitumor immunity. RNA. 2025 02 19; 31(3):395-401.
    View in: PubMed
    Score: 0.688
  5. Quantitative profiling of m6A at single base resolution across the life cycle of rice and Arabidopsis. Nat Commun. 2024 Jun 07; 15(1):4881.
    View in: PubMed
    Score: 0.656
  6. The YTHDF proteins display distinct cellular functions on m6A-modified RNA. Trends Biochem Sci. 2024 07; 49(7):611-621.
    View in: PubMed
    Score: 0.650
  7. FTO mediates LINE1 m6A demethylation and chromatin regulation in mESCs and mouse development. Science. 2022 05 27; 376(6596):968-973.
    View in: PubMed
    Score: 0.567
  8. Chromatin and transcriptional regulation by reversible RNA methylation. Curr Opin Cell Biol. 2021 06; 70:109-115.
    View in: PubMed
    Score: 0.523
  9. m6 A RNA methylation: from mechanisms to therapeutic potential. EMBO J. 2021 02 01; 40(3):e105977.
    View in: PubMed
    Score: 0.519
  10. LEAD-m6 A-seq for Locus-Specific Detection of N6 -Methyladenosine and Quantification of Differential Methylation. Angew Chem Int Ed Engl. 2021 01 11; 60(2):873-880.
    View in: PubMed
    Score: 0.512
  11. Genetic analyses support the contribution of mRNA N6-methyladenosine (m6A) modification to human disease heritability. Nat Genet. 2020 09; 52(9):939-949.
    View in: PubMed
    Score: 0.499
  12. YTHDF2 promotes mitotic entry and is regulated by cell cycle mediators. PLoS Biol. 2020 04; 18(4):e3000664.
    View in: PubMed
    Score: 0.491
  13. N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription. Science. 2020 01 31; 367(6477):580-586.
    View in: PubMed
    Score: 0.484
  14. The RNA-binding protein FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs. J Biol Chem. 2019 12 27; 294(52):19889-19895.
    View in: PubMed
    Score: 0.478
  15. Site-specific m6A editing. Nat Chem Biol. 2019 09; 15(9):848-849.
    View in: PubMed
    Score: 0.471
  16. Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers. Mol Cell. 2019 05 16; 74(4):640-650.
    View in: PubMed
    Score: 0.462
  17. Regulation of Gene Expression by N6-methyladenosine in Cancer. Trends Cell Biol. 2019 06; 29(6):487-499.
    View in: PubMed
    Score: 0.457
  18. Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells. Nature. 2019 02; 566(7743):270-274.
    View in: PubMed
    Score: 0.453
  19. High-Resolution Mapping of N 6-Methyladenosine Using m6A Crosslinking Immunoprecipitation Sequencing (m6A-CLIP-Seq). Methods Mol Biol. 2019; 1870:69-79.
    View in: PubMed
    Score: 0.450
  20. Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm. Mol Cell. 2018 09 20; 71(6):973-985.e5.
    View in: PubMed
    Score: 0.440
  21. m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nat Cell Biol. 2018 09; 20(9):1074-1083.
    View in: PubMed
    Score: 0.439
  22. Phasing Gene Expression: mRNA N6-Methyladenosine Regulates Temporal Progression of Mammalian Cortical Neurogenesis. Biochemistry. 2018 02 20; 57(7):1055-1056.
    View in: PubMed
    Score: 0.422
  23. Identifying the m6A Methylome by Affinity Purification and Sequencing. Methods Mol Biol. 2018; 1649:49-57.
    View in: PubMed
    Score: 0.420
  24. Making Changes: N6-Methyladenosine-Mediated Decay Drives the Endothelial-to-Hematopoietic Transition. Biochemistry. 2017 11 21; 56(46):6077-6078.
    View in: PubMed
    Score: 0.415
  25. Epitranscriptomic influences on development and disease. Genome Biol. 2017 10 23; 18(1):197.
    View in: PubMed
    Score: 0.414
  26. YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs. Elife. 2017 10 06; 6.
    View in: PubMed
    Score: 0.413
  27. Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis. Cell Res. 2017 Sep; 27(9):1115-1127.
    View in: PubMed
    Score: 0.409
  28. m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition. Nature. 2017 02 23; 542(7642):475-478.
    View in: PubMed
    Score: 0.395
  29. YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA. Cell Res. 2017 Mar; 27(3):315-328.
    View in: PubMed
    Score: 0.393
  30. A glance at N(6)-methyladenosine in transcript isoforms. Nat Methods. 2016 07 28; 13(8):624-5.
    View in: PubMed
    Score: 0.380
  31. Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing. Trends Genet. 2016 06; 32(6):320-321.
    View in: PubMed
    Score: 0.372
  32. High-Resolution Mapping of N6-Methyladenosine in Transcriptome and Genome Using a Photo-Crosslinking-Assisted Strategy. Methods Enzymol. 2015; 560:161-85.
    View in: PubMed
    Score: 0.354
  33. RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation. Genes Dev. 2015 Jul 01; 29(13):1343-55.
    View in: PubMed
    Score: 0.353
  34. Widespread occurrence of N6-methyladenosine in bacterial mRNA. Nucleic Acids Res. 2015 Jul 27; 43(13):6557-67.
    View in: PubMed
    Score: 0.352
  35. N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency. Cell. 2015 Jun 04; 161(6):1388-99.
    View in: PubMed
    Score: 0.351
  36. Preparation of Human Nuclear RNA m6A Methyltransferases and Demethylases and Biochemical Characterization of Their Catalytic Activity. Methods Enzymol. 2015; 560:117-30.
    View in: PubMed
    Score: 0.348
  37. Unique features of the m6A methylome in Arabidopsis thaliana. Nat Commun. 2014 Nov 28; 5:5630.
    View in: PubMed
    Score: 0.339
  38. Gene expression regulation mediated through reversible m6A RNA methylation. Nat Rev Genet. 2014 May; 15(5):293-306.
    View in: PubMed
    Score: 0.323
  39. A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation. Nat Chem Biol. 2014 Feb; 10(2):93-5.
    View in: PubMed
    Score: 0.317
  40. N6-methyladenosine-dependent regulation of messenger RNA stability. Nature. 2014 Jan 02; 505(7481):117-20.
    View in: PubMed
    Score: 0.316
  41. FTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA. Nat Commun. 2013; 4:1798.
    View in: PubMed
    Score: 0.297
  42. Reversible RNA adenosine methylation in biological regulation. Trends Genet. 2013 Feb; 29(2):108-15.
    View in: PubMed
    Score: 0.295
  43. N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat Chem Biol. 2011 Oct 16; 7(12):885-7.
    View in: PubMed
    Score: 0.273
  44. Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked protein-DNA system. Nucleic Acids Res. 2010 Jul; 38(13):4415-25.
    View in: PubMed
    Score: 0.244
  45. m6A RNA methylation modulates IFN-?-stimulated intestinal epithelial cell-intrinsic antiparasitic defense. PLoS Pathog. 2026 07; 22(7):e1014442.
    View in: PubMed
    Score: 0.190
  46. mRNA m6A modifications and the RNA-binding protein YTHDF1 affect translational control in both normal and pathological learning. Proc Natl Acad Sci U S A. 2026 Apr 21; 123(16):e2518250123.
    View in: PubMed
    Score: 0.186
  47. RNA modifications in cancer: from biological insights to therapeutic targets. Bioorg Med Chem. 2026 Jan 01; 132:118432.
    View in: PubMed
    Score: 0.180
  48. RNA modification systems as therapeutic targets. Nat Rev Drug Discov. 2026 01; 25(1):59-78.
    View in: PubMed
    Score: 0.179
  49. FTO degrader impairs ribosome biogenesis and protein translation in acute myeloid leukemia. Sci Adv. 2025 Aug 15; 11(33):eadv7648.
    View in: PubMed
    Score: 0.178
  50. IGF2BP3 promotes mRNA degradation through internal m7G modification. Nat Commun. 2024 08 28; 15(1):7421.
    View in: PubMed
    Score: 0.166
  51. m6A RNA methylation regulates mitochondrial function. Hum Mol Genet. 2024 05 18; 33(11):969-980.
    View in: PubMed
    Score: 0.163
  52. RBFOX2 recognizes N6-methyladenosine to suppress transcription and block myeloid leukaemia differentiation. Nat Cell Biol. 2023 09; 25(9):1359-1368.
    View in: PubMed
    Score: 0.155
  53. Mammalian DNA N6-methyladenosine: Challenges and new insights. Mol Cell. 2023 02 02; 83(3):343-351.
    View in: PubMed
    Score: 0.149
  54. Exon architecture controls mRNA m6A suppression and gene expression. Science. 2023 02 17; 379(6633):677-682.
    View in: PubMed
    Score: 0.149
  55. Transcriptome-wide profiling and quantification of N6-methyladenosine by enzyme-assisted adenosine deamination. Nat Biotechnol. 2023 07; 41(7):993-1003.
    View in: PubMed
    Score: 0.148
  56. Detection of m6A RNA modifications at single-nucleotide resolution using m6A-selective allyl chemical labeling and sequencing. STAR Protoc. 2022 12 16; 3(4):101677.
    View in: PubMed
    Score: 0.145
  57. METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis. Nat Cell Biol. 2022 02; 24(2):205-216.
    View in: PubMed
    Score: 0.140
  58. Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis. Nat Commun. 2021 04 12; 12(1):2183.
    View in: PubMed
    Score: 0.132
  59. N6 -methyladenosine modification of lncRNA Pvt1 governs epidermal stemness. EMBO J. 2021 04 15; 40(8):e106276.
    View in: PubMed
    Score: 0.131
  60. N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation. Dev Cell. 2020 12 21; 55(6):737-753.e7.
    View in: PubMed
    Score: 0.128
  61. YTHDF3 Induces the Translation of m6A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis. Cancer Cell. 2020 12 14; 38(6):857-871.e7.
    View in: PubMed
    Score: 0.128
  62. A New Model of Spontaneous Colitis in Mice Induced by Deletion of an RNA m6A Methyltransferase Component METTL14 in T Cells. Cell Mol Gastroenterol Hepatol. 2020; 10(4):747-761.
    View in: PubMed
    Score: 0.125
  63. Control of Early B Cell Development by the RNA N6-Methyladenosine Methylation. Cell Rep. 2020 06 30; 31(13):107819.
    View in: PubMed
    Score: 0.125
  64. REPIC: a database for exploring the N6-methyladenosine methylome. Genome Biol. 2020 04 28; 21(1):100.
    View in: PubMed
    Score: 0.123
  65. m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination. Neuron. 2020 01 22; 105(2):293-309.e5.
    View in: PubMed
    Score: 0.121
  66. Evolution of a reverse transcriptase to map N1-methyladenosine in human messenger RNA. Nat Methods. 2019 12; 16(12):1281-1288.
    View in: PubMed
    Score: 0.118
  67. Regulation of Co-transcriptional Pre-mRNA Splicing by m6A through the Low-Complexity Protein hnRNPG. Mol Cell. 2019 10 03; 76(1):70-81.e9.
    View in: PubMed
    Score: 0.118
  68. FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export. Cell Rep. 2019 07 23; 28(4):845-854.e5.
    View in: PubMed
    Score: 0.117
  69. m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade. Nat Commun. 2019 06 25; 10(1):2782.
    View in: PubMed
    Score: 0.116
  70. Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally. Nature. 2019 03; 567(7748):414-419.
    View in: PubMed
    Score: 0.114
  71. Transcriptome-wide reprogramming of N6-methyladenosine modification by the mouse microbiome. Cell Res. 2019 02; 29(2):167-170.
    View in: PubMed
    Score: 0.112
  72. N6-Methyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation. Nat Chem Biol. 2019 01; 15(1):88-94.
    View in: PubMed
    Score: 0.112
  73. Circadian Clock Regulation of Hepatic Lipid Metabolism by Modulation of m6A mRNA Methylation. Cell Rep. 2018 11 13; 25(7):1816-1828.e4.
    View in: PubMed
    Score: 0.111
  74. A dynamic N6-methyladenosine methylome regulates intrinsic and acquired resistance to tyrosine kinase inhibitors. Cell Res. 2018 11; 28(11):1062-1076.
    View in: PubMed
    Score: 0.111
  75. RNA modifications modulate gene expression during development. Science. 2018 09 28; 361(6409):1346-1349.
    View in: PubMed
    Score: 0.110
  76. Chemical Modifications in the Life of an mRNA Transcript. Annu Rev Genet. 2018 11 23; 52:349-372.
    View in: PubMed
    Score: 0.110
  77. Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal. Mol Cell. 2018 03 15; 69(6):1028-1038.e6.
    View in: PubMed
    Score: 0.106
  78. Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation. Nat Cell Biol. 2018 03; 20(3):285-295.
    View in: PubMed
    Score: 0.106
  79. METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification. Cell Stem Cell. 2018 02 01; 22(2):191-205.e9.
    View in: PubMed
    Score: 0.105
  80. Our views of dynamic N6-methyladenosine RNA methylation. RNA. 2018 03; 24(3):268-272.
    View in: PubMed
    Score: 0.104
  81. ALKBH10B Is an RNA N6-Methyladenosine Demethylase Affecting Arabidopsis Floral Transition. Plant Cell. 2017 12; 29(12):2995-3011.
    View in: PubMed
    Score: 0.104
  82. m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells. Cell Rep. 2017 03 14; 18(11):2622-2634.
    View in: PubMed
    Score: 0.099
  83. Evolution of transcript modification by N6-methyladenosine in primates. Genome Res. 2017 03; 27(3):385-392.
    View in: PubMed
    Score: 0.098
  84. FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N6-Methyladenosine RNA Demethylase. Cancer Cell. 2017 01 09; 31(1):127-141.
    View in: PubMed
    Score: 0.098
  85. Post-transcriptional gene regulation by mRNA modifications. Nat Rev Mol Cell Biol. 2017 01; 18(1):31-42.
    View in: PubMed
    Score: 0.097
  86. ALKBH1-Mediated tRNA Demethylation Regulates Translation. Cell. 2016 Oct 20; 167(3):816-828.e16.
    View in: PubMed
    Score: 0.096
  87. The dynamic N(1)-methyladenosine methylome in eukaryotic messenger RNA. Nature. 2016 Feb 25; 530(7591):441-6.
    View in: PubMed
    Score: 0.092
  88. Nucleic Acid Modifications in Regulation of Gene Expression. Cell Chem Biol. 2016 Jan 21; 23(1):74-85.
    View in: PubMed
    Score: 0.092
  89. N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions. Nature. 2015 Feb 26; 518(7540):560-4.
    View in: PubMed
    Score: 0.086
  90. Nucleic acid modifications with epigenetic significance. Curr Opin Chem Biol. 2012 Dec; 16(5-6):516-24.
    View in: PubMed
    Score: 0.073
  91. YTHDFs as radiotherapy checkpoints in tumor immunity. J Exp Med. 2025 Aug 04; 222(8).
    View in: PubMed
    Score: 0.044
  92. Small-molecule inhibition of the METTL3/METTL14 complex suppresses neuroblastoma tumor growth and promotes differentiation. Cell Rep. 2024 05 28; 43(5):114165.
    View in: PubMed
    Score: 0.041
  93. CSTF2 mediated mRNA N6-methyladenosine modification drives pancreatic ductal adenocarcinoma m6A subtypes. Nat Commun. 2023 10 10; 14(1):6334.
    View in: PubMed
    Score: 0.039
  94. A lncRNA from the FTO locus acts as a suppressor of the m6A writer complex and p53 tumor suppression signaling. Mol Cell. 2023 08 03; 83(15):2692-2708.e7.
    View in: PubMed
    Score: 0.039
  95. Globally reduced N6-methyladenosine (m6A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration. Nat Neurosci. 2023 08; 26(8):1328-1338.
    View in: PubMed
    Score: 0.038
  96. The METTL5-TRMT112 N6-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylation. J Biol Chem. 2022 03; 298(3):101590.
    View in: PubMed
    Score: 0.035
  97. ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing. Nat Cell Biol. 2021 07; 23(7):684-691.
    View in: PubMed
    Score: 0.034
  98. YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma. Mol Cancer. 2019 11 18; 18(1):163.
    View in: PubMed
    Score: 0.030
  99. R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling. Cell. 2018 01 11; 172(1-2):90-105.e23.
    View in: PubMed
    Score: 0.026
  100. Synthesis of a FTO inhibitor with anticonvulsant activity. ACS Chem Neurosci. 2014 Aug 20; 5(8):658-65.
    View in: PubMed
    Score: 0.020
  101. Genome-wide analysis of N1-methyl-adenosine modification in human tRNAs. RNA. 2010 Jul; 16(7):1317-27.
    View in: PubMed
    Score: 0.015
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.