Chuan He to Animals
This is a "connection" page, showing publications Chuan He has written about Animals.
Connection Strength
3.299
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Sequencing of N6-methyl-deoxyadenosine at single-base resolution across the mammalian genome. Mol Cell. 2024 Feb 01; 84(3):596-610.e6.
Score: 0.061
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Base-Resolution Sequencing Methods for Whole-Transcriptome Quantification of mRNA Modifications. Acc Chem Res. 2024 Jan 02; 57(1):47-58.
Score: 0.061
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BID-seq for transcriptome-wide quantitative sequencing of mRNA pseudouridine at base resolution. Nat Protoc. 2024 Feb; 19(2):517-538.
Score: 0.060
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6mA-METL-9 axis regulates innate immunity in C. elegans. Cell Res. 2023 08; 33(8):581-582.
Score: 0.059
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YTHDF2/m6 A/NF-?B axis controls anti-tumor immunity by regulating intratumoral Tregs. EMBO J. 2023 08 01; 42(15):e113126.
Score: 0.059
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Advances in targeting RNA modifications for anticancer therapy. Trends Cancer. 2023 07; 9(7):528-542.
Score: 0.058
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Mammalian DNA N6-methyladenosine: Challenges and new insights. Mol Cell. 2023 02 02; 83(3):343-351.
Score: 0.057
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Exon architecture controls mRNA m6A suppression and gene expression. Science. 2023 02 17; 379(6633):677-682.
Score: 0.057
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m6A-SAC-seq for quantitative whole transcriptome m6A profiling. Nat Protoc. 2023 02; 18(2):626-657.
Score: 0.057
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m7G-quant-seq: Quantitative Detection of RNA Internal N7-Methylguanosine. ACS Chem Biol. 2022 12 16; 17(12):3306-3312.
Score: 0.056
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Quantitative sequencing using BID-seq uncovers abundant pseudouridines in mammalian mRNA at base resolution. Nat Biotechnol. 2023 03; 41(3):344-354.
Score: 0.056
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FTO mediates LINE1 m6A demethylation and chromatin regulation in mESCs and mouse development. Science. 2022 05 27; 376(6596):968-973.
Score: 0.054
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m6A RNA modifications are measured at single-base resolution across the mammalian transcriptome. Nat Biotechnol. 2022 08; 40(8):1210-1219.
Score: 0.054
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m6 A RNA methylation: from mechanisms to therapeutic potential. EMBO J. 2021 02 01; 40(3):e105977.
Score: 0.050
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Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m6A Methylation. Mol Cell. 2020 11 19; 80(4):633-647.e7.
Score: 0.049
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Direct DNA crosslinking with CAP-C uncovers transcription-dependent chromatin organization at high resolution. Nat Biotechnol. 2021 02; 39(2):225-235.
Score: 0.048
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A New Model of Spontaneous Colitis in Mice Induced by Deletion of an RNA m6A Methyltransferase Component METTL14 in T Cells. Cell Mol Gastroenterol Hepatol. 2020; 10(4):747-761.
Score: 0.048
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Kethoxal-assisted single-stranded DNA sequencing captures global transcription dynamics and enhancer activity in situ. Nat Methods. 2020 05; 17(5):515-523.
Score: 0.047
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N6-Deoxyadenosine Methylation in Mammalian Mitochondrial DNA. Mol Cell. 2020 05 07; 78(3):382-395.e8.
Score: 0.047
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DNA 5-Methylcytosine-Specific Amplification and Sequencing. J Am Chem Soc. 2020 03 11; 142(10):4539-4543.
Score: 0.047
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Keth-seq for transcriptome-wide RNA structure mapping. Nat Chem Biol. 2020 05; 16(5):489-492.
Score: 0.047
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N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription. Science. 2020 01 31; 367(6477):580-586.
Score: 0.046
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The RNA-binding protein FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs. J Biol Chem. 2019 12 27; 294(52):19889-19895.
Score: 0.046
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Transcriptome-wide Mapping of Internal N7-Methylguanosine Methylome in Mammalian mRNA. Mol Cell. 2019 06 20; 74(6):1304-1316.e8.
Score: 0.044
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Regulation of Gene Expression by N6-methyladenosine in Cancer. Trends Cell Biol. 2019 06; 29(6):487-499.
Score: 0.044
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RNA modifications modulate gene expression during development. Science. 2018 09 28; 361(6409):1346-1349.
Score: 0.042
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Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm. Mol Cell. 2018 09 20; 71(6):973-985.e5.
Score: 0.042
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m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nat Cell Biol. 2018 09; 20(9):1074-1083.
Score: 0.042
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Phasing Gene Expression: mRNA N6-Methyladenosine Regulates Temporal Progression of Mammalian Cortical Neurogenesis. Biochemistry. 2018 02 20; 57(7):1055-1056.
Score: 0.041
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Making Changes: N6-Methyladenosine-Mediated Decay Drives the Endothelial-to-Hematopoietic Transition. Biochemistry. 2017 11 21; 56(46):6077-6078.
Score: 0.040
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Epigenetics: Making your mark on DNA. Nat Chem. 2017 Oct 24; 9(11):1040-1042.
Score: 0.040
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Epitranscriptomic influences on development and disease. Genome Biol. 2017 10 23; 18(1):197.
Score: 0.040
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"Gamete On" for m6A: YTHDF2 Exerts Essential Functions in Female Fertility. Mol Cell. 2017 Sep 21; 67(6):903-905.
Score: 0.040
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Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis. Cell Res. 2017 Sep; 27(9):1115-1127.
Score: 0.039
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Dynamic RNA Modifications in Gene Expression Regulation. Cell. 2017 Jun 15; 169(7):1187-1200.
Score: 0.039
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DNA N6-methyladenine in metazoans: functional epigenetic mark or bystander? Nat Struct Mol Biol. 2017 Jun 06; 24(6):503-506.
Score: 0.039
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m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition. Nature. 2017 02 23; 542(7642):475-478.
Score: 0.038
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Developing drugs targeting transition metal homeostasis. Curr Opin Chem Biol. 2017 Apr; 37:26-32.
Score: 0.038
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The emerging biology of RNA post-transcriptional modifications. RNA Biol. 2017 02; 14(2):156-163.
Score: 0.037
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Post-transcriptional gene regulation by mRNA modifications. Nat Rev Mol Cell Biol. 2017 01; 18(1):31-42.
Score: 0.037
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Abundant DNA 6mA methylation during early embryogenesis of zebrafish and pig. Nat Commun. 2016 10 07; 7:13052.
Score: 0.037
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A Highly Sensitive and Robust Method for Genome-wide 5hmC Profiling of Rare Cell Populations. Mol Cell. 2016 08 18; 63(4):711-719.
Score: 0.036
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Nucleic Acid Modifications in Regulation of Gene Expression. Cell Chem Biol. 2016 Jan 21; 23(1):74-85.
Score: 0.035
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RNA epigenetics--chemical messages for posttranscriptional gene regulation. Curr Opin Chem Biol. 2016 Feb; 30:46-51.
Score: 0.035
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Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation. Nat Chem. 2015 Dec; 7(12):968-79.
Score: 0.035
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RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation. Genes Dev. 2015 Jul 01; 29(13):1343-55.
Score: 0.034
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Introduction: epigenetics. Chem Rev. 2015 Mar 25; 115(6):2223-4.
Score: 0.033
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TET family proteins: oxidation activity, interacting molecules, and functions in diseases. Chem Rev. 2015 Mar 25; 115(6):2225-39.
Score: 0.033
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Detection of mismatched 5-hydroxymethyluracil in DNA by selective chemical labeling. Methods. 2015 Jan 15; 72:16-20.
Score: 0.032
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Pseudouridine in a new era of RNA modifications. Cell Res. 2015 Feb; 25(2):153-4.
Score: 0.032
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Cancer: Damage prevention targeted. Nature. 2014 Apr 10; 508(7495):191-2.
Score: 0.031
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Gene expression regulation mediated through reversible m6A RNA methylation. Nat Rev Genet. 2014 May; 15(5):293-306.
Score: 0.031
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Nucleic acid oxidation in DNA damage repair and epigenetics. Chem Rev. 2014 Apr 23; 114(8):4602-20.
Score: 0.031
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Crystal structure of the RNA demethylase ALKBH5 from zebrafish. FEBS Lett. 2014 Mar 18; 588(6):892-8.
Score: 0.031
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A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation. Nat Chem Biol. 2014 Feb; 10(2):93-5.
Score: 0.030
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Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming. Cell. 2013 Apr 25; 153(3):678-91.
Score: 0.029
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Sprouts of RNA epigenetics: the discovery of mammalian RNA demethylases. RNA Biol. 2013 Jun; 10(6):915-8.
Score: 0.029
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Proteome-wide quantification and characterization of oxidation-sensitive cysteines in pathogenic bacteria. Cell Host Microbe. 2013 Mar 13; 13(3):358-70.
Score: 0.029
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Tet-mediated covalent labelling of 5-methylcytosine for its genome-wide detection and sequencing. Nat Commun. 2013; 4:1517.
Score: 0.028
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FTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA. Nat Commun. 2013; 4:1798.
Score: 0.028
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Tet-assisted bisulfite sequencing of 5-hydroxymethylcytosine. Nat Protoc. 2012 Dec; 7(12):2159-70.
Score: 0.028
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Mapping recently identified nucleotide variants in the genome and transcriptome. Nat Biotechnol. 2012 Nov; 30(11):1107-16.
Score: 0.028
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Nucleic acid modifications with epigenetic significance. Curr Opin Chem Biol. 2012 Dec; 16(5-6):516-24.
Score: 0.028
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Protein cysteine phosphorylation of SarA/MgrA family transcriptional regulators mediates bacterial virulence and antibiotic resistance. Proc Natl Acad Sci U S A. 2012 Sep 18; 109(38):15461-6.
Score: 0.028
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Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome. Cell. 2012 Jun 08; 149(6):1368-80.
Score: 0.027
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Targeting MgrA-mediated virulence regulation in Staphylococcus aureus. Chem Biol. 2011 Aug 26; 18(8):1032-41.
Score: 0.026
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Bioorthogonal labeling of 5-hydroxymethylcytosine in genomic DNA and diazirine-based DNA photo-cross-linking probes. Acc Chem Res. 2011 Sep 20; 44(9):709-17.
Score: 0.025
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Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine. Nat Biotechnol. 2011 Jan; 29(1):68-72.
Score: 0.025
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Grand challenge commentary: RNA epigenetics? Nat Chem Biol. 2010 Dec; 6(12):863-5.
Score: 0.025
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Golden pigment production and virulence gene expression are affected by metabolisms in Staphylococcus aureus. J Bacteriol. 2010 Jun; 192(12):3068-77.
Score: 0.024
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Dynamic copper(I) imaging in mammalian cells with a genetically encoded fluorescent copper(I) sensor. J Am Chem Soc. 2010 Mar 03; 132(8):2567-9.
Score: 0.023
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Pseudomonas aeruginosa OspR is an oxidative stress sensing regulator that affects pigment production, antibiotic resistance and dissemination during infection. Mol Microbiol. 2010 Jan; 75(1):76-91.
Score: 0.023
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A new oxidative sensing and regulation pathway mediated by the MgrA homologue SarZ in Staphylococcus aureus. Mol Microbiol. 2009 Jan; 71(1):198-211.
Score: 0.021
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Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO. FEBS Lett. 2008 Oct 15; 582(23-24):3313-9.
Score: 0.021
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Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins. J Inorg Biochem. 2006 Apr; 100(4):670-8.
Score: 0.018
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Direct reversal of DNA alkylation damage. Chem Rev. 2006 Feb; 106(2):215-32.
Score: 0.018
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METTL14 is a chromatin regulator independent of its RNA N6-methyladenosine methyltransferase activity. Protein Cell. 2023 09 14; 14(9):683-697.
Score: 0.015
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YTHDF2 inhibition potentiates radiotherapy antitumor efficacy. Cancer Cell. 2023 07 10; 41(7):1294-1308.e8.
Score: 0.015
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Transcriptome-wide profiling and quantification of N6-methyladenosine by enzyme-assisted adenosine deamination. Nat Biotechnol. 2023 Jul; 41(7):993-1003.
Score: 0.014
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N6-adenomethylation of GsdmC is essential for Lgr5+ stem cell survival to maintain normal colonic epithelial morphogenesis. Dev Cell. 2022 08 22; 57(16):1976-1994.e8.
Score: 0.014
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The METTL5-TRMT112 N6-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylation. J Biol Chem. 2022 03; 298(3):101590.
Score: 0.013
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HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease. Mol Cell. 2021 12 16; 81(24):5052-5065.e6.
Score: 0.013
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METTL14 facilitates global genome repair and suppresses skin tumorigenesis. Proc Natl Acad Sci U S A. 2021 08 31; 118(35).
Score: 0.013
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Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis. Nat Commun. 2021 04 12; 12(1):2183.
Score: 0.013
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N6 -methyladenosine modification of lncRNA Pvt1 governs epidermal stemness. EMBO J. 2021 04 15; 40(8):e106276.
Score: 0.013
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N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation. Dev Cell. 2020 12 21; 55(6):737-753.e7.
Score: 0.012
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Control of Early B Cell Development by the RNA N6-Methyladenosine Methylation. Cell Rep. 2020 06 30; 31(13):107819.
Score: 0.012
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REPIC: a database for exploring the N6-methyladenosine methylome. Genome Biol. 2020 04 28; 21(1):100.
Score: 0.012
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m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination. Neuron. 2020 01 22; 105(2):293-309.e5.
Score: 0.012
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RADAR: differential analysis of MeRIP-seq data with a random effect model. Genome Biol. 2019 12 23; 20(1):294.
Score: 0.012
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FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export. Cell Rep. 2019 07 23; 28(4):845-854.e5.
Score: 0.011
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m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade. Nat Commun. 2019 06 25; 10(1):2782.
Score: 0.011
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METTL14 is essential for ß-cell survival and insulin secretion. Biochim Biophys Acta Mol Basis Dis. 2019 09 01; 1865(9):2138-2148.
Score: 0.011
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Inhibition of Copper Transport Induces Apoptosis in Triple-Negative Breast Cancer Cells and Suppresses Tumor Angiogenesis. Mol Cancer Ther. 2019 05; 18(5):873-885.
Score: 0.011
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Transcriptome-wide reprogramming of N6-methyladenosine modification by the mouse microbiome. Cell Res. 2019 02; 29(2):167-170.
Score: 0.011
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Circadian Clock Regulation of Hepatic Lipid Metabolism by Modulation of m6A mRNA Methylation. Cell Rep. 2018 11 13; 25(7):1816-1828.e4.
Score: 0.011
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m6A facilitates hippocampus-dependent learning and memory through YTHDF1. Nature. 2018 11; 563(7730):249-253.
Score: 0.011
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Mettl14 Is Essential for Epitranscriptomic Regulation of Striatal Function and Learning. Neuron. 2018 07 25; 99(2):283-292.e5.
Score: 0.010
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Evolution of transcript modification by N6-methyladenosine in primates. Genome Res. 2017 03; 27(3):385-392.
Score: 0.009
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The dynamic N(1)-methyladenosine methylome in eukaryotic messenger RNA. Nature. 2016 Feb 25; 530(7591):441-6.
Score: 0.009
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Identification of MLL-fusion/MYC?miR-26?TET1 signaling circuit in MLL-rearranged leukemia. Cancer Lett. 2016 Mar 28; 372(2):157-65.
Score: 0.009
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DNA N(6)-methyladenine: a new epigenetic mark in eukaryotes? Nat Rev Mol Cell Biol. 2015 Dec; 16(12):705-10.
Score: 0.009
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Base-resolution detection of N4-methylcytosine in genomic DNA using 4mC-Tet-assisted-bisulfite- sequencing. Nucleic Acids Res. 2015 Dec 02; 43(21):e148.
Score: 0.008
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Base-resolution maps of 5-formylcytosine and 5-carboxylcytosine reveal genome-wide DNA demethylation dynamics. Cell Res. 2015 Mar; 25(3):386-9.
Score: 0.008
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Blood-brain barrier permeable gold nanoparticles: an efficient delivery platform for enhanced malignant glioma therapy and imaging. Small. 2014 Dec 29; 10(24):5137-50.
Score: 0.008
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Synthesis of a FTO inhibitor with anticonvulsant activity. ACS Chem Neurosci. 2014 Aug 20; 5(8):658-65.
Score: 0.008
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HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis. Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24):9920-5.
Score: 0.007
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ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. Mol Cell. 2013 Jan 10; 49(1):18-29.
Score: 0.007
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Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia. Cancer Cell. 2012 Oct 16; 22(4):524-35.
Score: 0.007
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Capsule anchoring in Bacillus anthracis occurs by a transpeptidation reaction that is inhibited by capsidin. Mol Microbiol. 2009 Jan; 71(2):404-20.
Score: 0.005