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Chuan He to Methyltransferases

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This is a "connection" page, showing publications Chuan He has written about Methyltransferases.
Chuan He
Connection Strength
8.923
Methyltransferases
  1. Acetylation of METTL3: A negative regulator of m6A deposition on chromatin-associated regulatory RNAs. Mol Cell. 2025 Apr 03; 85(7):1251-1252.
    View in: PubMed
    Score: 0.808
  2. Advances in targeting RNA modifications for anticancer therapy. Trends Cancer. 2023 07; 9(7):528-542.
    View in: PubMed
    Score: 0.707
  3. Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m6A Methylation. Mol Cell. 2020 11 19; 80(4):633-647.e7.
    View in: PubMed
    Score: 0.597
  4. A New Model of Spontaneous Colitis in Mice Induced by Deletion of an RNA m6A Methyltransferase Component METTL14 in T Cells. Cell Mol Gastroenterol Hepatol. 2020; 10(4):747-761.
    View in: PubMed
    Score: 0.581
  5. N6-Deoxyadenosine Methylation in Mammalian Mitochondrial DNA. Mol Cell. 2020 05 07; 78(3):382-395.e8.
    View in: PubMed
    Score: 0.569
  6. N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription. Science. 2020 01 31; 367(6477):580-586.
    View in: PubMed
    Score: 0.563
  7. Transcriptome-wide Mapping of Internal N7-Methylguanosine Methylome in Mammalian mRNA. Mol Cell. 2019 06 20; 74(6):1304-1316.e8.
    View in: PubMed
    Score: 0.535
  8. Gene expression regulation mediated through reversible m6A RNA methylation. Nat Rev Genet. 2014 May; 15(5):293-306.
    View in: PubMed
    Score: 0.376
  9. A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation. Nat Chem Biol. 2014 Feb; 10(2):93-5.
    View in: PubMed
    Score: 0.368
  10. RNA modification systems as therapeutic targets. Nat Rev Drug Discov. 2026 01; 25(1):59-78.
    View in: PubMed
    Score: 0.208
  11. IGF2BP3 promotes mRNA degradation through internal m7G modification. Nat Commun. 2024 Aug 28; 15(1):7421.
    View in: PubMed
    Score: 0.194
  12. m6A RNA methylation regulates mitochondrial function. Hum Mol Genet. 2024 05 18; 33(11):969-980.
    View in: PubMed
    Score: 0.190
  13. Small-molecule inhibition of the METTL3/METTL14 complex suppresses neuroblastoma tumor growth and promotes differentiation. Cell Rep. 2024 05 28; 43(5):114165.
    View in: PubMed
    Score: 0.189
  14. Chemical manipulation of m1A mediates its detection in human tRNA. RNA. 2024 04 16; 30(5):548-559.
    View in: PubMed
    Score: 0.189
  15. METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis. Nat Cell Biol. 2022 02; 24(2):205-216.
    View in: PubMed
    Score: 0.162
  16. The METTL5-TRMT112 N6-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylation. J Biol Chem. 2022 03; 298(3):101590.
    View in: PubMed
    Score: 0.162
  17. HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease. Mol Cell. 2021 12 16; 81(24):5052-5065.e6.
    View in: PubMed
    Score: 0.160
  18. METTL14 facilitates global genome repair and suppresses skin tumorigenesis. Proc Natl Acad Sci U S A. 2021 08 31; 118(35).
    View in: PubMed
    Score: 0.157
  19. m6 A RNA methylation: from mechanisms to therapeutic potential. EMBO J. 2021 02 01; 40(3):e105977.
    View in: PubMed
    Score: 0.151
  20. N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation. Dev Cell. 2020 12 21; 55(6):737-753.e7.
    View in: PubMed
    Score: 0.149
  21. Upregulation of METTL14 mediates the elevation of PERP mRNA N6 adenosine methylation promoting the growth and metastasis of pancreatic cancer. Mol Cancer. 2020 08 25; 19(1):130.
    View in: PubMed
    Score: 0.147
  22. m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination. Neuron. 2020 01 22; 105(2):293-309.e5.
    View in: PubMed
    Score: 0.140
  23. METTL14 is essential for ß-cell survival and insulin secretion. Biochim Biophys Acta Mol Basis Dis. 2019 09 01; 1865(9):2138-2148.
    View in: PubMed
    Score: 0.134
  24. N6-Methyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation. Nat Chem Biol. 2019 01; 15(1):88-94.
    View in: PubMed
    Score: 0.130
  25. RNA modifications modulate gene expression during development. Science. 2018 09 28; 361(6409):1346-1349.
    View in: PubMed
    Score: 0.129
  26. m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nat Cell Biol. 2018 09; 20(9):1074-1083.
    View in: PubMed
    Score: 0.128
  27. Mettl14 Is Essential for Epitranscriptomic Regulation of Striatal Function and Learning. Neuron. 2018 07 25; 99(2):283-292.e5.
    View in: PubMed
    Score: 0.126
  28. METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification. Cell Stem Cell. 2018 02 01; 22(2):191-205.e9.
    View in: PubMed
    Score: 0.122
  29. A new modification for mammalian messenger RNA. J Biol Chem. 2017 09 01; 292(35):14704-14705.
    View in: PubMed
    Score: 0.119
  30. RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation. Genes Dev. 2015 Jul 01; 29(13):1343-55.
    View in: PubMed
    Score: 0.103
  31. Preparation of Human Nuclear RNA m6A Methyltransferases and Demethylases and Biochemical Characterization of Their Catalytic Activity. Methods Enzymol. 2015; 560:117-30.
    View in: PubMed
    Score: 0.101
  32. Unique features of the m6A methylome in Arabidopsis thaliana. Nat Commun. 2014 Nov 28; 5:5630.
    View in: PubMed
    Score: 0.099
  33. Direct reversal of DNA alkylation damage. Chem Rev. 2006 Feb; 106(2):215-32.
    View in: PubMed
    Score: 0.053
  34. METTL14 is a chromatin regulator independent of its RNA N6-methyladenosine methyltransferase activity. Protein Cell. 2023 09 14; 14(9):683-697.
    View in: PubMed
    Score: 0.045
  35. A lncRNA from the FTO locus acts as a suppressor of the m6A writer complex and p53 tumor suppression signaling. Mol Cell. 2023 08 03; 83(15):2692-2708.e7.
    View in: PubMed
    Score: 0.045
  36. N6 -methyladenosine modification of lncRNA Pvt1 governs epidermal stemness. EMBO J. 2021 04 15; 40(8):e106276.
    View in: PubMed
    Score: 0.038
  37. Control of Early B Cell Development by the RNA N6-Methyladenosine Methylation. Cell Rep. 2020 06 30; 31(13):107819.
    View in: PubMed
    Score: 0.036
  38. Detailed modeling of positive selection improves detection of cancer driver genes. Nat Commun. 2019 07 30; 10(1):3399.
    View in: PubMed
    Score: 0.034
  39. Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally. Nature. 2019 03; 567(7748):414-419.
    View in: PubMed
    Score: 0.033
  40. Circadian Clock Regulation of Hepatic Lipid Metabolism by Modulation of m6A mRNA Methylation. Cell Rep. 2018 11 13; 25(7):1816-1828.e4.
    View in: PubMed
    Score: 0.032
  41. m6A facilitates hippocampus-dependent learning and memory through YTHDF1. Nature. 2018 11; 563(7730):249-253.
    View in: PubMed
    Score: 0.032
  42. RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia. Nat Commun. 2018 03 21; 9(1):1163.
    View in: PubMed
    Score: 0.031
  43. m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells. Cell Rep. 2017 03 14; 18(11):2622-2634.
    View in: PubMed
    Score: 0.029
  44. Genome-wide analysis of N1-methyl-adenosine modification in human tRNAs. RNA. 2010 Jul; 16(7):1317-27.
    View in: PubMed
    Score: 0.018
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.