Chuan He to Humans
This is a "connection" page, showing publications Chuan He has written about Humans.
Connection Strength
2.501
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RNA modification systems as therapeutic targets. Nat Rev Drug Discov. 2026 01; 25(1):59-78.
Score: 0.030
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FTO degrader impairs ribosome biogenesis and protein translation in acute myeloid leukemia. Sci Adv. 2025 Aug 15; 11(33):eadv7648.
Score: 0.030
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Acetylation of METTL3: A negative regulator of m6A deposition on chromatin-associated regulatory RNAs. Mol Cell. 2025 Apr 03; 85(7):1251-1252.
Score: 0.029
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N6-methyladenosine reader YTHDF2 in cell state transition and antitumor immunity. RNA. 2025 Feb 19; 31(3):395-401.
Score: 0.029
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snoRNA-facilitated protein secretion revealed by transcriptome-wide snoRNA target identification. Cell. 2025 Jan 23; 188(2):465-483.e22.
Score: 0.029
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RNA m5C oxidation by TET2 regulates chromatin state and leukaemogenesis. Nature. 2024 Oct; 634(8035):986-994.
Score: 0.028
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IGF2BP3 promotes mRNA degradation through internal m7G modification. Nat Commun. 2024 Aug 28; 15(1):7421.
Score: 0.028
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PTPN2 copper-sensing relays copper level fluctuations into EGFR/CREB activation and associated CTR1 transcriptional repression. Nat Commun. 2024 Aug 13; 15(1):6947.
Score: 0.028
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Quantitative analysis of cis-regulatory elements in transcription with KAS-ATAC-seq. Nat Commun. 2024 Aug 10; 15(1):6852.
Score: 0.028
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Pseudouridine Detection and Quantification Using Bisulfite Incorporation Hindered Ligation. ACS Chem Biol. 2024 08 16; 19(8):1813-1819.
Score: 0.028
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LABS: linear amplification-based bisulfite sequencing for ultrasensitive cancer detection from cell-free DNA. Genome Biol. 2024 06 14; 25(1):157.
Score: 0.028
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The YTHDF proteins display distinct cellular functions on m6A-modified RNA. Trends Biochem Sci. 2024 07; 49(7):611-621.
Score: 0.028
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Chemical manipulation of m1A mediates its detection in human tRNA. RNA. 2024 04 16; 30(5):548-559.
Score: 0.027
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KARR-seq reveals cellular higher-order RNA structures and RNA-RNA interactions. Nat Biotechnol. 2024 Dec; 42(12):1909-1920.
Score: 0.027
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Ultrafast bisulfite sequencing detection of 5-methylcytosine in DNA and RNA. Nat Biotechnol. 2024 Oct; 42(10):1559-1570.
Score: 0.027
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FMRP phosphorylation modulates neuronal translation through YTHDF1. Mol Cell. 2023 12 07; 83(23):4304-4317.e8.
Score: 0.027
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Base-resolution quantitative DAMM-seq for mapping RNA methylations in tRNA and mitochondrial polycistronic RNA. Methods Enzymol. 2023; 692:39-54.
Score: 0.026
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RBFOX2 recognizes N6-methyladenosine to suppress transcription and block myeloid leukaemia differentiation. Nat Cell Biol. 2023 09; 25(9):1359-1368.
Score: 0.026
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Advances in targeting RNA modifications for anticancer therapy. Trends Cancer. 2023 07; 9(7):528-542.
Score: 0.026
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Exon architecture controls mRNA m6A suppression and gene expression. Science. 2023 02 17; 379(6633):677-682.
Score: 0.025
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The mechanism underlying redundant functions of the YTHDF proteins. Genome Biol. 2023 01 24; 24(1):17.
Score: 0.025
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spKAS-seq reveals R-loop dynamics using low-input materials by detecting single-stranded DNA with strand specificity. Sci Adv. 2022 12 02; 8(48):eabq2166.
Score: 0.025
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m7G-quant-seq: Quantitative Detection of RNA Internal N7-Methylguanosine. ACS Chem Biol. 2022 12 16; 17(12):3306-3312.
Score: 0.025
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Quantitative sequencing using BID-seq uncovers abundant pseudouridines in mammalian mRNA at base resolution. Nat Biotechnol. 2023 03; 41(3):344-354.
Score: 0.025
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Ex vivo gliadin stimulation of intestinal cells. Methods Cell Biol. 2023; 179:13-20.
Score: 0.025
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m6A RNA modifications are measured at single-base resolution across the mammalian transcriptome. Nat Biotechnol. 2022 08; 40(8):1210-1219.
Score: 0.024
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KAS-seq: genome-wide sequencing of single-stranded DNA by N3-kethoxal-assisted labeling. Nat Protoc. 2022 Feb; 17(2):402-420.
Score: 0.023
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Chromatin and transcriptional regulation by reversible RNA methylation. Curr Opin Cell Biol. 2021 06; 70:109-115.
Score: 0.022
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m6 A RNA methylation: from mechanisms to therapeutic potential. EMBO J. 2021 02 01; 40(3):e105977.
Score: 0.022
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Transcriptome-Wide Detection of Internal N7-Methylguanosine. Methods Mol Biol. 2021; 2298:97-104.
Score: 0.022
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A human tissue map of 5-hydroxymethylcytosines exhibits tissue specificity through gene and enhancer modulation. Nat Commun. 2020 12 02; 11(1):6161.
Score: 0.022
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Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m6A Methylation. Mol Cell. 2020 11 19; 80(4):633-647.e7.
Score: 0.022
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Genetic analyses support the contribution of mRNA N6-methyladenosine (m6A) modification to human disease heritability. Nat Genet. 2020 09; 52(9):939-949.
Score: 0.021
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YTHDF2 promotes mitotic entry and is regulated by cell cycle mediators. PLoS Biol. 2020 04; 18(4):e3000664.
Score: 0.021
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Kethoxal-assisted single-stranded DNA sequencing captures global transcription dynamics and enhancer activity in situ. Nat Methods. 2020 05; 17(5):515-523.
Score: 0.021
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N6-Deoxyadenosine Methylation in Mammalian Mitochondrial DNA. Mol Cell. 2020 05 07; 78(3):382-395.e8.
Score: 0.021
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DNA 5-Methylcytosine-Specific Amplification and Sequencing. J Am Chem Soc. 2020 03 11; 142(10):4539-4543.
Score: 0.021
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Keth-seq for transcriptome-wide RNA structure mapping. Nat Chem Biol. 2020 05; 16(5):489-492.
Score: 0.021
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The RNA-binding protein FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs. J Biol Chem. 2019 12 27; 294(52):19889-19895.
Score: 0.020
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Transcriptome-wide Mapping of Internal N7-Methylguanosine Methylome in Mammalian mRNA. Mol Cell. 2019 06 20; 74(6):1304-1316.e8.
Score: 0.019
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Regulation of Gene Expression by N6-methyladenosine in Cancer. Trends Cell Biol. 2019 06; 29(6):487-499.
Score: 0.019
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Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells. Nature. 2019 02; 566(7743):270-274.
Score: 0.019
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Special Issue on Regulating the Central Dogma. Biochemistry. 2019 02 05; 58(5):295-296.
Score: 0.019
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High-Resolution Mapping of N 6-Methyladenosine Using m6A Crosslinking Immunoprecipitation Sequencing (m6A-CLIP-Seq). Methods Mol Biol. 2019; 1870:69-79.
Score: 0.019
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Single base resolution mapping of 2'-O-methylation sites in human mRNA and in 3' terminal ends of small RNAs. Methods. 2019 03 01; 156:85-90.
Score: 0.019
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RNA modifications modulate gene expression during development. Science. 2018 09 28; 361(6409):1346-1349.
Score: 0.019
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Chemical Modifications in the Life of an mRNA Transcript. Annu Rev Genet. 2018 11 23; 52:349-372.
Score: 0.019
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Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm. Mol Cell. 2018 09 20; 71(6):973-985.e5.
Score: 0.019
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m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nat Cell Biol. 2018 09; 20(9):1074-1083.
Score: 0.019
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Phasing Gene Expression: mRNA N6-Methyladenosine Regulates Temporal Progression of Mammalian Cortical Neurogenesis. Biochemistry. 2018 02 20; 57(7):1055-1056.
Score: 0.018
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Tet-Assisted Bisulfite Sequencing (TAB-seq). Methods Mol Biol. 2018; 1708:645-663.
Score: 0.018
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Making Changes: N6-Methyladenosine-Mediated Decay Drives the Endothelial-to-Hematopoietic Transition. Biochemistry. 2017 11 21; 56(46):6077-6078.
Score: 0.018
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Epigenetics: Making your mark on DNA. Nat Chem. 2017 Oct 24; 9(11):1040-1042.
Score: 0.018
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Epitranscriptomic influences on development and disease. Genome Biol. 2017 10 23; 18(1):197.
Score: 0.018
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YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs. Elife. 2017 10 06; 6.
Score: 0.017
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"Gamete On" for m6A: YTHDF2 Exerts Essential Functions in Female Fertility. Mol Cell. 2017 Sep 21; 67(6):903-905.
Score: 0.017
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Dynamic RNA Modifications in Gene Expression Regulation. Cell. 2017 Jun 15; 169(7):1187-1200.
Score: 0.017
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Nm-seq maps 2'-O-methylation sites in human mRNA with base precision. Nat Methods. 2017 Jul; 14(7):695-698.
Score: 0.017
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YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA. Cell Res. 2017 Mar; 27(3):315-328.
Score: 0.017
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Developing drugs targeting transition metal homeostasis. Curr Opin Chem Biol. 2017 Apr; 37:26-32.
Score: 0.017
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The emerging biology of RNA post-transcriptional modifications. RNA Biol. 2017 02; 14(2):156-163.
Score: 0.017
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Post-transcriptional gene regulation by mRNA modifications. Nat Rev Mol Cell Biol. 2017 01; 18(1):31-42.
Score: 0.016
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ALKBH1-Mediated tRNA Demethylation Regulates Translation. Cell. 2016 Oct 20; 167(3):816-828.e16.
Score: 0.016
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A glance at N(6)-methyladenosine in transcript isoforms. Nat Methods. 2016 07 28; 13(8):624-5.
Score: 0.016
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Nucleic Acid Modifications in Regulation of Gene Expression. Cell Chem Biol. 2016 Jan 21; 23(1):74-85.
Score: 0.016
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RNA epigenetics--chemical messages for posttranscriptional gene regulation. Curr Opin Chem Biol. 2016 Feb; 30:46-51.
Score: 0.015
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Detecting hepatocellular carcinoma in blood. Cell Res. 2015 Dec; 25(12):1279-80.
Score: 0.015
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Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation. Nat Chem. 2015 Dec; 7(12):968-79.
Score: 0.015
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High-Resolution Mapping of N6-Methyladenosine in Transcriptome and Genome Using a Photo-Crosslinking-Assisted Strategy. Methods Enzymol. 2015; 560:161-85.
Score: 0.015
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RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation. Genes Dev. 2015 Jul 01; 29(13):1343-55.
Score: 0.015
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Decoding the transcriptome and DNA methylome of human primordial germ cells. Sci China Life Sci. 2015 Jul; 58(7):729-30.
Score: 0.015
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N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency. Cell. 2015 Jun 04; 161(6):1388-99.
Score: 0.015
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Preparation of Human Nuclear RNA m6A Methyltransferases and Demethylases and Biochemical Characterization of Their Catalytic Activity. Methods Enzymol. 2015; 560:117-30.
Score: 0.015
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Introduction: epigenetics. Chem Rev. 2015 Mar 25; 115(6):2223-4.
Score: 0.015
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TET family proteins: oxidation activity, interacting molecules, and functions in diseases. Chem Rev. 2015 Mar 25; 115(6):2225-39.
Score: 0.015
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High-resolution N(6) -methyladenosine (m(6) A) map using photo-crosslinking-assisted m(6) A sequencing. Angew Chem Int Ed Engl. 2015 Jan 26; 54(5):1587-90.
Score: 0.014
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Pseudouridine in a new era of RNA modifications. Cell Res. 2015 Feb; 25(2):153-4.
Score: 0.014
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Reading RNA methylation codes through methyl-specific binding proteins. RNA Biol. 2014; 11(6):669-72.
Score: 0.014
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Cancer: Damage prevention targeted. Nature. 2014 Apr 10; 508(7495):191-2.
Score: 0.014
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Gene expression regulation mediated through reversible m6A RNA methylation. Nat Rev Genet. 2014 May; 15(5):293-306.
Score: 0.014
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Nucleic acid oxidation in DNA damage repair and epigenetics. Chem Rev. 2014 Apr 23; 114(8):4602-20.
Score: 0.014
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A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation. Nat Chem Biol. 2014 Feb; 10(2):93-5.
Score: 0.013
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N6-methyladenosine-dependent regulation of messenger RNA stability. Nature. 2014 Jan 02; 505(7481):117-20.
Score: 0.013
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A highly sensitive and genetically encoded fluorescent reporter for ratiometric monitoring of quinones in living cells. Chem Commun (Camb). 2013 Sep 21; 49(73):8027-9.
Score: 0.013
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Sprouts of RNA epigenetics: the discovery of mammalian RNA demethylases. RNA Biol. 2013 Jun; 10(6):915-8.
Score: 0.013
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Proteome-wide quantification and characterization of oxidation-sensitive cysteines in pathogenic bacteria. Cell Host Microbe. 2013 Mar 13; 13(3):358-70.
Score: 0.013
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Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR. Proc Natl Acad Sci U S A. 2013 Mar 26; 110(13):5010-5.
Score: 0.013
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FTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA. Nat Commun. 2013; 4:1798.
Score: 0.013
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Reversible RNA adenosine methylation in biological regulation. Trends Genet. 2013 Feb; 29(2):108-15.
Score: 0.013
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Mapping recently identified nucleotide variants in the genome and transcriptome. Nat Biotechnol. 2012 Nov; 30(11):1107-16.
Score: 0.012
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Nucleic acid modifications with epigenetic significance. Curr Opin Chem Biol. 2012 Dec; 16(5-6):516-24.
Score: 0.012
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A selective fluorescent probe for carbon monoxide imaging in living cells. Angew Chem Int Ed Engl. 2012 Sep 17; 51(38):9652-6.
Score: 0.012
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Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome. Cell. 2012 Jun 08; 149(6):1368-80.
Score: 0.012
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Staphylococcus aureus CymR is a new thiol-based oxidation-sensing regulator of stress resistance and oxidative response. J Biol Chem. 2012 Jun 15; 287(25):21102-9.
Score: 0.012
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Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA. Nat Chem Biol. 2012 Feb 12; 8(4):328-30.
Score: 0.012
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N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat Chem Biol. 2011 Oct 16; 7(12):885-7.
Score: 0.012
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Selective fluorescent probes for live-cell monitoring of sulphide. Nat Commun. 2011 Oct 11; 2:495.
Score: 0.012
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Targeting MgrA-mediated virulence regulation in Staphylococcus aureus. Chem Biol. 2011 Aug 26; 18(8):1032-41.
Score: 0.011
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Structural and biochemical characterization of N5-carboxyaminoimidazole ribonucleotide synthetase and N5-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus. Acta Crystallogr D Biol Crystallogr. 2011 Aug; 67(Pt 8):707-15.
Score: 0.011
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Detection of 5-hydroxymethylcytosine in DNA by transferring a keto-glucose by using T4 phage ß-glucosyltransferase. Chembiochem. 2011 Jul 25; 12(11):1682-5.
Score: 0.011
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Bioorthogonal labeling of 5-hydroxymethylcytosine in genomic DNA and diazirine-based DNA photo-cross-linking probes. Acc Chem Res. 2011 Sep 20; 44(9):709-17.
Score: 0.011
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Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine. Nat Biotechnol. 2011 Jan; 29(1):68-72.
Score: 0.011
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Grand challenge commentary: RNA epigenetics? Nat Chem Biol. 2010 Dec; 6(12):863-5.
Score: 0.011
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The AlkB domain of mammalian ABH8 catalyzes hydroxylation of 5-methoxycarbonylmethyluridine at the wobble position of tRNA. Angew Chem Int Ed Engl. 2010 Nov 15; 49(47):8885-8.
Score: 0.011
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Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase. Nature. 2010 Nov 11; 468(7321):330-3.
Score: 0.011
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A non-heme iron-mediated chemical demethylation in DNA and RNA. Acc Chem Res. 2009 Apr 21; 42(4):519-29.
Score: 0.010
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Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO. FEBS Lett. 2008 Oct 15; 582(23-24):3313-9.
Score: 0.009
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Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA. Nature. 2008 Apr 24; 452(7190):961-5.
Score: 0.009
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Diazirine-based DNA photo-cross-linking probes for the study of protein-DNA interactions. Angew Chem Int Ed Engl. 2008; 47(1):90-3.
Score: 0.009
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Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins. J Inorg Biochem. 2006 Apr; 100(4):670-8.
Score: 0.008
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Direct reversal of DNA alkylation damage. Chem Rev. 2006 Feb; 106(2):215-32.
Score: 0.008
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Direct repair of the exocyclic DNA adduct 1,N6-ethenoadenine by the DNA repair AlkB proteins. J Am Chem Soc. 2005 Oct 26; 127(42):14594-5.
Score: 0.008
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The structure of the human AGT protein bound to DNA and its implications for damage detection. J Mol Biol. 2005 Jul 22; 350(4):657-66.
Score: 0.008
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YTHDFs as radiotherapy checkpoints in tumor immunity. J Exp Med. 2025 Aug 04; 222(8).
Score: 0.007
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Radiation-induced amphiregulin drives tumour metastasis. Nature. 2025 Jul; 643(8072):810-819.
Score: 0.007
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Targeting DTX2/UFD1-mediated FTO degradation to regulate antitumor immunity. Proc Natl Acad Sci U S A. 2024 Dec 17; 121(51):e2407910121.
Score: 0.007
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YTHDF1 loss in dendritic cells potentiates radiation-induced antitumor immunity via STING-dependent type I IFN production. J Clin Invest. 2024 Dec 02; 134(23).
Score: 0.007
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Dynamics of RNA localization to nuclear speckles are connected to splicing efficiency. Sci Adv. 2024 10 18; 10(42):eadp7727.
Score: 0.007
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5-Hydroxymethylated Biomarkers in Cell-Free DNA Predict Occult Colorectal Cancer up to 36 Months Before Diagnosis in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. JCO Precis Oncol. 2024 Oct; 8:e2400277.
Score: 0.007
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Targeting the Dendritic Cell-Secreted Immunoregulatory Cytokine CCL22 Alleviates Radioresistance. Clin Cancer Res. 2024 Oct 01; 30(19):4450-4463.
Score: 0.007
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RNA interacts with topoisomerase I to adjust DNA topology. Mol Cell. 2024 Sep 05; 84(17):3192-3208.e11.
Score: 0.007
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Characterizing Relationships between T-cell Inflammation and Outcomes in Patients with High-Risk Neuroblastoma According to Mesenchymal and Adrenergic Signatures. Cancer Res Commun. 2024 08 01; 4(8):2255-2266.
Score: 0.007
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m6A RNA methylation regulates mitochondrial function. Hum Mol Genet. 2024 05 18; 33(11):969-980.
Score: 0.007
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Small-molecule inhibition of the METTL3/METTL14 complex suppresses neuroblastoma tumor growth and promotes differentiation. Cell Rep. 2024 05 28; 43(5):114165.
Score: 0.007
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Protocol for detecting RBM33-binding sites in HEK293T cells using PAR-CLIP-seq. STAR Protoc. 2024 03 15; 5(1):102855.
Score: 0.007
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5-Hydroxymethylcytosine signals in serum are a predictor of chemoresistance in high-grade serous ovarian cancer. Gynecol Oncol. 2024 03; 182:82-90.
Score: 0.007
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Bromodomain-Containing Protein 9 Regulates Signaling Pathways and Reprograms the Epigenome in Immortalized Human Uterine Fibroid Cells. Int J Mol Sci. 2024 Jan 11; 25(2).
Score: 0.007
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5-Hydroxymethylcytosine Profiling of Cell-Free DNA Identifies Bivalent Genes That Are Prognostic of Survival in High-Risk Neuroblastoma. JCO Precis Oncol. 2024 01; 8:e2300297.
Score: 0.007
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RNA m6A methylation and MDSCs: Roles and therapeutic implications for radiotherapy. Med. 2023 12 08; 4(12):863-874.
Score: 0.007
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Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity. Nature. 2023 11; 623(7989):1034-1043.
Score: 0.007
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Analysis of genome-wide 5-hydroxymethylation of blood samples stored in different anticoagulants: opportunities for the expansion of clinical resources for epigenetic research. Epigenetics. 2023 12; 18(1):2271692.
Score: 0.007
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Adrenergic and mesenchymal signatures are identifiable in cell-free DNA and correlate with metastatic disease burden in children with neuroblastoma. Pediatr Blood Cancer. 2024 Jan; 71(1):e30735.
Score: 0.007
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CSTF2 mediated mRNA N6-methyladenosine modification drives pancreatic ductal adenocarcinoma m6A subtypes. Nat Commun. 2023 10 10; 14(1):6334.
Score: 0.007
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How do DNA repair proteins locate potential base lesions? a chemical crosslinking method to investigate O6-alkylguanine-DNA alkyltransferases. Chem Biol. 2003 Sep; 10(9):827-35.
Score: 0.007
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Globally reduced N6-methyladenosine (m6A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration. Nat Neurosci. 2023 08; 26(8):1328-1338.
Score: 0.006
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Nm-Mut-seq: a base-resolution quantitative method for mapping transcriptome-wide 2'-O-methylation. Cell Res. 2023 09; 33(9):727-730.
Score: 0.006
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PETCH-DB: a Portal for Exploring Tissue-specific and Complex disease-associated 5-Hydroxymethylcytosines. Database (Oxford). 2023 06 10; 2023.
Score: 0.006
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PETCH-DB: a Portal for Exploring Tissue-specific and Complex disease-associated 5-Hydroxymethylcytosines. Database (Oxford). 2023 06 10; 2023.
Score: 0.006
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RBM33 is a unique m6A RNA-binding protein that regulates ALKBH5 demethylase activity and substrate selectivity. Mol Cell. 2023 06 15; 83(12):2003-2019.e6.
Score: 0.006
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YTHDF2 inhibition potentiates radiotherapy antitumor efficacy. Cancer Cell. 2023 07 10; 41(7):1294-1308.e8.
Score: 0.006
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Genome-Wide Mapping Implicates 5-Hydroxymethylcytosines in Diabetes Mellitus and Alzheimer's Disease. J Alzheimers Dis. 2023; 93(3):1135-1151.
Score: 0.006
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Genome-wide profiling of 5-hydroxymethylcytosines in circulating cell-free DNA reveals population-specific pathways in the development of multiple myeloma. J Hematol Oncol. 2022 08 16; 15(1):106.
Score: 0.006
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N6-adenomethylation of GsdmC is essential for Lgr5+ stem cell survival to maintain normal colonic epithelial morphogenesis. Dev Cell. 2022 08 22; 57(16):1976-1994.e8.
Score: 0.006
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Development of Mild Chemical Catalysis Conditions for m1A-to-m6A Rearrangement on RNA. ACS Chem Biol. 2022 06 17; 17(6):1334-1342.
Score: 0.006
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METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis. Nat Cell Biol. 2022 02; 24(2):205-216.
Score: 0.006
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Utility of Perioperative Measurement of Cell-Free DNA and Circulating Tumor DNA in Informing the Prognosis of GI Cancers: A Systematic Review. JCO Precis Oncol. 2022 02; 6:e2100337.
Score: 0.006
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HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease. Mol Cell. 2021 12 16; 81(24):5052-5065.e6.
Score: 0.006
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METTL14 facilitates global genome repair and suppresses skin tumorigenesis. Proc Natl Acad Sci U S A. 2021 08 31; 118(35).
Score: 0.006
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RNA demethylation increases the yield and biomass of rice and potato plants in field trials. Nat Biotechnol. 2021 12; 39(12):1581-1588.
Score: 0.006
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ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing. Nat Cell Biol. 2021 07; 23(7):684-691.
Score: 0.006
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Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis. Nat Commun. 2021 04 12; 12(1):2183.
Score: 0.006
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EGFR/SRC/ERK-stabilized YTHDF2 promotes cholesterol dysregulation and invasive growth of glioblastoma. Nat Commun. 2021 01 08; 12(1):177.
Score: 0.005
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N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation. Dev Cell. 2020 12 21; 55(6):737-753.e7.
Score: 0.005
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YTHDF3 Induces the Translation of m6A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis. Cancer Cell. 2020 12 14; 38(6):857-871.e7.
Score: 0.005
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Upregulation of METTL14 mediates the elevation of PERP mRNA N6 adenosine methylation promoting the growth and metastasis of pancreatic cancer. Mol Cancer. 2020 08 25; 19(1):130.
Score: 0.005
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RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia. Cell Stem Cell. 2020 07 02; 27(1):64-80.e9.
Score: 0.005
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REPIC: a database for exploring the N6-methyladenosine methylome. Genome Biol. 2020 04 28; 21(1):100.
Score: 0.005
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RADAR: differential analysis of MeRIP-seq data with a random effect model. Genome Biol. 2019 12 23; 20(1):294.
Score: 0.005
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5-Hydroxymethylcytosine Profiles in Circulating Cell-Free DNA Associate with Disease Burden in Children with Neuroblastoma. Clin Cancer Res. 2020 03 15; 26(6):1309-1317.
Score: 0.005
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YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma. Mol Cancer. 2019 11 18; 18(1):163.
Score: 0.005
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Prognostic implications of 5-hydroxymethylcytosines from circulating cell-free DNA in diffuse large B-cell lymphoma. Blood Adv. 2019 10 08; 3(19):2790-2799.
Score: 0.005
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5-Hydroxymethylcytosines in Circulating Cell-Free DNA Reveal Vascular Complications of Type 2 Diabetes. Clin Chem. 2019 11; 65(11):1414-1425.
Score: 0.005
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Evolution of a reverse transcriptase to map N1-methyladenosine in human messenger RNA. Nat Methods. 2019 12; 16(12):1281-1288.
Score: 0.005
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Regulation of Co-transcriptional Pre-mRNA Splicing by m6A through the Low-Complexity Protein hnRNPG. Mol Cell. 2019 10 03; 76(1):70-81.e9.
Score: 0.005
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Detailed modeling of positive selection improves detection of cancer driver genes. Nat Commun. 2019 07 30; 10(1):3399.
Score: 0.005
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m6A mRNA Methylation Regulates Human ß-Cell Biology in Physiological States and in Type 2 Diabetes. Nat Metab. 2019 08; 1(8):765-774.
Score: 0.005
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m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade. Nat Commun. 2019 06 25; 10(1):2782.
Score: 0.005
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Cytokine-Regulated Phosphorylation and Activation of TET2 by JAK2 in Hematopoiesis. Cancer Discov. 2019 06; 9(6):778-795.
Score: 0.005
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Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally. Nature. 2019 03; 567(7748):414-419.
Score: 0.005
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Inhibition of Copper Transport Induces Apoptosis in Triple-Negative Breast Cancer Cells and Suppresses Tumor Angiogenesis. Mol Cancer Ther. 2019 05; 18(5):873-885.
Score: 0.005
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Transcriptome-wide reprogramming of N6-methyladenosine modification by the mouse microbiome. Cell Res. 2019 02; 29(2):167-170.
Score: 0.005
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N6-Methyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation. Nat Chem Biol. 2019 01; 15(1):88-94.
Score: 0.005
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Circadian Clock Regulation of Hepatic Lipid Metabolism by Modulation of m6A mRNA Methylation. Cell Rep. 2018 11 13; 25(7):1816-1828.e4.
Score: 0.005
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A dynamic N6-methyladenosine methylome regulates intrinsic and acquired resistance to tyrosine kinase inhibitors. Cell Res. 2018 11; 28(11):1062-1076.
Score: 0.005
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RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia. Nat Commun. 2018 03 21; 9(1):1163.
Score: 0.005
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Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal. Mol Cell. 2018 03 15; 69(6):1028-1038.e6.
Score: 0.005
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Wnt signaling pathway involvement in genotypic and phenotypic variations in Waardenburg syndrome type 2 with MITF mutations. J Hum Genet. 2018 May; 63(5):639-646.
Score: 0.005
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Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation. Nat Cell Biol. 2018 03; 20(3):285-295.
Score: 0.004
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METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification. Cell Stem Cell. 2018 02 01; 22(2):191-205.e9.
Score: 0.004
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R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling. Cell. 2018 01 11; 172(1-2):90-105.e23.
Score: 0.004
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Functional analysis of a SOX10 gene mutation associated with Waardenburg syndrome II. Biochem Biophys Res Commun. 2017 11 04; 493(1):258-262.
Score: 0.004
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m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells. Cell Rep. 2017 03 14; 18(11):2622-2634.
Score: 0.004
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Evolution of transcript modification by N6-methyladenosine in primates. Genome Res. 2017 03; 27(3):385-392.
Score: 0.004
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FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N6-Methyladenosine RNA Demethylase. Cancer Cell. 2017 01 09; 31(1):127-141.
Score: 0.004
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Base-Resolution Analysis of Cisplatin-DNA Adducts at the Genome Scale. Angew Chem Int Ed Engl. 2016 11 07; 55(46):14246-14249.
Score: 0.004
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FOXA1 potentiates lineage-specific enhancer activation through modulating TET1 expression and function. Nucleic Acids Res. 2016 09 30; 44(17):8153-64.
Score: 0.004
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ALKBHs-facilitated RNA modifications and de-modifications. DNA Repair (Amst). 2016 08; 44:87-91.
Score: 0.004
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DNA cytosine hydroxymethylation levels are distinct among non-overlapping classes of peripheral blood leukocytes. J Immunol Methods. 2016 09; 436:1-15.
Score: 0.004
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The dynamic N(1)-methyladenosine methylome in eukaryotic messenger RNA. Nature. 2016 Feb 25; 530(7591):441-6.
Score: 0.004
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Identification of MLL-fusion/MYC?miR-26?TET1 signaling circuit in MLL-rearranged leukemia. Cancer Lett. 2016 Mar 28; 372(2):157-65.
Score: 0.004
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Efficient and quantitative high-throughput tRNA sequencing. Nat Methods. 2015 Sep; 12(9):835-837.
Score: 0.004
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Live Cell MicroRNA Imaging Using Cascade Hybridization Reaction. J Am Chem Soc. 2015 May 20; 137(19):6116-9.
Score: 0.004
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N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions. Nature. 2015 Feb 26; 518(7540):560-4.
Score: 0.004
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Synthesis of a FTO inhibitor with anticonvulsant activity. ACS Chem Neurosci. 2014 Aug 20; 5(8):658-65.
Score: 0.003
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Identification and functional analysis of a novel mutation in the SOX10 gene associated with Waardenburg syndrome type IV. Gene. 2014 Mar 15; 538(1):36-41.
Score: 0.003
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Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis. Cell Rep. 2014 Jan 16; 6(1):231-244.
Score: 0.003
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TET1 plays an essential oncogenic role in MLL-rearranged leukemia. Proc Natl Acad Sci U S A. 2013 Jul 16; 110(29):11994-9.
Score: 0.003
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HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis. Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24):9920-5.
Score: 0.003
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ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. Mol Cell. 2013 Jan 10; 49(1):18-29.
Score: 0.003
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Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia. Cancer Cell. 2012 Oct 16; 22(4):524-35.
Score: 0.003
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Genome-wide analysis of N1-methyl-adenosine modification in human tRNAs. RNA. 2010 Jul; 16(7):1317-27.
Score: 0.003