The University of Chicago Header Logo

Connection

Chuan He to RNA, Messenger

This is a "connection" page, showing publications Chuan He has written about RNA, Messenger.
Connection Strength

17.367
  1. Quantitative RNA pseudouridine maps reveal multilayered translation control through plant rRNA, tRNA and mRNA pseudouridylation. Nat Plants. 2025 02; 11(2):234-247.
    View in: PubMed
    Score: 0.557
  2. IGF2BP3 promotes mRNA degradation through internal m7G modification. Nat Commun. 2024 08 28; 15(1):7421.
    View in: PubMed
    Score: 0.543
  3. Quantitative profiling of m6A at single base resolution across the life cycle of rice and Arabidopsis. Nat Commun. 2024 Jun 07; 15(1):4881.
    View in: PubMed
    Score: 0.535
  4. Exon architecture controls mRNA m6A suppression and gene expression. Science. 2023 02 17; 379(6633):677-682.
    View in: PubMed
    Score: 0.487
  5. Quantitative sequencing using BID-seq uncovers abundant pseudouridines in mammalian mRNA at base resolution. Nat Biotechnol. 2023 03; 41(3):344-354.
    View in: PubMed
    Score: 0.478
  6. FTO mediates LINE1 m6A demethylation and chromatin regulation in mESCs and mouse development. Science. 2022 05 27; 376(6596):968-973.
    View in: PubMed
    Score: 0.463
  7. m6 A RNA methylation: from mechanisms to therapeutic potential. EMBO J. 2021 02 01; 40(3):e105977.
    View in: PubMed
    Score: 0.423
  8. Genetic analyses support the contribution of mRNA N6-methyladenosine (m6A) modification to human disease heritability. Nat Genet. 2020 09; 52(9):939-949.
    View in: PubMed
    Score: 0.407
  9. The RNA-binding protein FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs. J Biol Chem. 2019 12 27; 294(52):19889-19895.
    View in: PubMed
    Score: 0.390
  10. Site-specific m6A editing. Nat Chem Biol. 2019 09; 15(9):848-849.
    View in: PubMed
    Score: 0.384
  11. Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers. Mol Cell. 2019 05 16; 74(4):640-650.
    View in: PubMed
    Score: 0.377
  12. Transcriptome-wide Mapping of Internal N7-Methylguanosine Methylome in Mammalian mRNA. Mol Cell. 2019 06 20; 74(6):1304-1316.e8.
    View in: PubMed
    Score: 0.375
  13. Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells. Nature. 2019 02; 566(7743):270-274.
    View in: PubMed
    Score: 0.369
  14. Single base resolution mapping of 2'-O-methylation sites in human mRNA and in 3' terminal ends of small RNAs. Methods. 2019 03 01; 156:85-90.
    View in: PubMed
    Score: 0.364
  15. RNA modifications modulate gene expression during development. Science. 2018 09 28; 361(6409):1346-1349.
    View in: PubMed
    Score: 0.360
  16. Chemical Modifications in the Life of an mRNA Transcript. Annu Rev Genet. 2018 11 23; 52:349-372.
    View in: PubMed
    Score: 0.360
  17. m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nat Cell Biol. 2018 09; 20(9):1074-1083.
    View in: PubMed
    Score: 0.358
  18. Phasing Gene Expression: mRNA N6-Methyladenosine Regulates Temporal Progression of Mammalian Cortical Neurogenesis. Biochemistry. 2018 02 20; 57(7):1055-1056.
    View in: PubMed
    Score: 0.344
  19. Epitranscriptomic influences on development and disease. Genome Biol. 2017 10 23; 18(1):197.
    View in: PubMed
    Score: 0.338
  20. YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs. Elife. 2017 10 06; 6.
    View in: PubMed
    Score: 0.337
  21. A new modification for mammalian messenger RNA. J Biol Chem. 2017 09 01; 292(35):14704-14705.
    View in: PubMed
    Score: 0.335
  22. Nm-seq maps 2'-O-methylation sites in human mRNA with base precision. Nat Methods. 2017 Jul; 14(7):695-698.
    View in: PubMed
    Score: 0.328
  23. Post-transcriptional gene regulation by mRNA modifications. Nat Rev Mol Cell Biol. 2017 01; 18(1):31-42.
    View in: PubMed
    Score: 0.316
  24. RNA epigenetics--chemical messages for posttranscriptional gene regulation. Curr Opin Chem Biol. 2016 Feb; 30:46-51.
    View in: PubMed
    Score: 0.296
  25. RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation. Genes Dev. 2015 Jul 01; 29(13):1343-55.
    View in: PubMed
    Score: 0.288
  26. Widespread occurrence of N6-methyladenosine in bacterial mRNA. Nucleic Acids Res. 2015 Jul 27; 43(13):6557-67.
    View in: PubMed
    Score: 0.287
  27. Unique features of the m6A methylome in Arabidopsis thaliana. Nat Commun. 2014 Nov 28; 5:5630.
    View in: PubMed
    Score: 0.276
  28. Pseudouridine in a new era of RNA modifications. Cell Res. 2015 Feb; 25(2):153-4.
    View in: PubMed
    Score: 0.275
  29. Reading RNA methylation codes through methyl-specific binding proteins. RNA Biol. 2014; 11(6):669-72.
    View in: PubMed
    Score: 0.265
  30. Gene expression regulation mediated through reversible m6A RNA methylation. Nat Rev Genet. 2014 May; 15(5):293-306.
    View in: PubMed
    Score: 0.264
  31. N6-methyladenosine-dependent regulation of messenger RNA stability. Nature. 2014 Jan 02; 505(7481):117-20.
    View in: PubMed
    Score: 0.258
  32. Sprouts of RNA epigenetics: the discovery of mammalian RNA demethylases. RNA Biol. 2013 Jun; 10(6):915-8.
    View in: PubMed
    Score: 0.247
  33. Reversible RNA adenosine methylation in biological regulation. Trends Genet. 2013 Feb; 29(2):108-15.
    View in: PubMed
    Score: 0.241
  34. N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat Chem Biol. 2011 Oct 16; 7(12):885-7.
    View in: PubMed
    Score: 0.223
  35. Intrinsically disordered regions restrain genomic targeting of RNA and histone demethylases in mammals and plants. Nat Genet. 2026 Aug; 58(8):2013-2026.
    View in: PubMed
    Score: 0.155
  36. mRNA m6A modifications and the RNA-binding protein YTHDF1 affect translational control in both normal and pathological learning. Proc Natl Acad Sci U S A. 2026 Apr 21; 123(16):e2518250123.
    View in: PubMed
    Score: 0.152
  37. Quantitative CRACI reveals transcriptome-wide distribution of RNA dihydrouridine at base resolution. Nat Commun. 2025 Oct 06; 16(1):8863.
    View in: PubMed
    Score: 0.147
  38. FTO degrader impairs ribosome biogenesis and protein translation in acute myeloid leukemia. Sci Adv. 2025 Aug 15; 11(33):eadv7648.
    View in: PubMed
    Score: 0.145
  39. N6-methyladenosine reader YTHDF2 in cell state transition and antitumor immunity. RNA. 2025 02 19; 31(3):395-401.
    View in: PubMed
    Score: 0.140
  40. snoRNA-facilitated protein secretion revealed by transcriptome-wide snoRNA target identification. Cell. 2025 Jan 23; 188(2):465-483.e22.
    View in: PubMed
    Score: 0.138
  41. Pseudouridine Detection and Quantification Using Bisulfite Incorporation Hindered Ligation. ACS Chem Biol. 2024 08 16; 19(8):1813-1819.
    View in: PubMed
    Score: 0.135
  42. Chemical manipulation of m1A mediates its detection in human tRNA. RNA. 2024 04 16; 30(5):548-559.
    View in: PubMed
    Score: 0.132
  43. KARR-seq reveals cellular higher-order RNA structures and RNA-RNA interactions. Nat Biotechnol. 2024 Dec; 42(12):1909-1920.
    View in: PubMed
    Score: 0.130
  44. Base-Resolution Sequencing Methods for Whole-Transcriptome Quantification of mRNA Modifications. Acc Chem Res. 2024 01 02; 57(1):47-58.
    View in: PubMed
    Score: 0.129
  45. mRNA accessibility within mRNPs as a determinant of gene expression. Trends Biochem Sci. 2024 03; 49(3):199-207.
    View in: PubMed
    Score: 0.129
  46. BID-seq for transcriptome-wide quantitative sequencing of mRNA pseudouridine at base resolution. Nat Protoc. 2024 02; 19(2):517-538.
    View in: PubMed
    Score: 0.129
  47. FMRP phosphorylation modulates neuronal translation through YTHDF1. Mol Cell. 2023 12 07; 83(23):4304-4317.e8.
    View in: PubMed
    Score: 0.128
  48. Advances in targeting RNA modifications for anticancer therapy. Trends Cancer. 2023 07; 9(7):528-542.
    View in: PubMed
    Score: 0.124
  49. BID-seq: The Quantitative and Base-Resolution Sequencing Method for RNA Pseudouridine. ACS Chem Biol. 2023 01 20; 18(1):4-6.
    View in: PubMed
    Score: 0.121
  50. m6A RNA modifications are measured at single-base resolution across the mammalian transcriptome. Nat Biotechnol. 2022 08; 40(8):1210-1219.
    View in: PubMed
    Score: 0.115
  51. METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis. Nat Cell Biol. 2022 02; 24(2):205-216.
    View in: PubMed
    Score: 0.114
  52. The METTL5-TRMT112 N6-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylation. J Biol Chem. 2022 03; 298(3):101590.
    View in: PubMed
    Score: 0.113
  53. Transcriptome-Wide Detection of Internal N7-Methylguanosine. Methods Mol Biol. 2021; 2298:97-104.
    View in: PubMed
    Score: 0.105
  54. N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation. Dev Cell. 2020 12 21; 55(6):737-753.e7.
    View in: PubMed
    Score: 0.105
  55. Upregulation of METTL14 mediates the elevation of PERP mRNA N6 adenosine methylation promoting the growth and metastasis of pancreatic cancer. Mol Cancer. 2020 08 25; 19(1):130.
    View in: PubMed
    Score: 0.103
  56. N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription. Science. 2020 01 31; 367(6477):580-586.
    View in: PubMed
    Score: 0.099
  57. m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination. Neuron. 2020 01 22; 105(2):293-309.e5.
    View in: PubMed
    Score: 0.098
  58. Evolution of a reverse transcriptase to map N1-methyladenosine in human messenger RNA. Nat Methods. 2019 12; 16(12):1281-1288.
    View in: PubMed
    Score: 0.096
  59. Regulation of Co-transcriptional Pre-mRNA Splicing by m6A through the Low-Complexity Protein hnRNPG. Mol Cell. 2019 10 03; 76(1):70-81.e9.
    View in: PubMed
    Score: 0.096
  60. m6A mRNA Methylation Regulates Human ß-Cell Biology in Physiological States and in Type 2 Diabetes. Nat Metab. 2019 08; 1(8):765-774.
    View in: PubMed
    Score: 0.095
  61. Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally. Nature. 2019 03; 567(7748):414-419.
    View in: PubMed
    Score: 0.093
  62. mRNA acetylation: a new addition to the epitranscriptome. Cell Res. 2019 02; 29(2):91-92.
    View in: PubMed
    Score: 0.092
  63. Transcriptome-wide reprogramming of N6-methyladenosine modification by the mouse microbiome. Cell Res. 2019 02; 29(2):167-170.
    View in: PubMed
    Score: 0.091
  64. Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm. Mol Cell. 2018 09 20; 71(6):973-985.e5.
    View in: PubMed
    Score: 0.090
  65. Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal. Mol Cell. 2018 03 15; 69(6):1028-1038.e6.
    View in: PubMed
    Score: 0.087
  66. Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation. Nat Cell Biol. 2018 03; 20(3):285-295.
    View in: PubMed
    Score: 0.086
  67. Our views of dynamic N6-methyladenosine RNA methylation. RNA. 2018 03; 24(3):268-272.
    View in: PubMed
    Score: 0.085
  68. Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis. Cell Res. 2017 Sep; 27(9):1115-1127.
    View in: PubMed
    Score: 0.083
  69. Evolution of transcript modification by N6-methyladenosine in primates. Genome Res. 2017 03; 27(3):385-392.
    View in: PubMed
    Score: 0.080
  70. The emerging biology of RNA post-transcriptional modifications. RNA Biol. 2017 02; 14(2):156-163.
    View in: PubMed
    Score: 0.080
  71. Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing. Trends Genet. 2016 06; 32(6):320-321.
    View in: PubMed
    Score: 0.076
  72. The dynamic N(1)-methyladenosine methylome in eukaryotic messenger RNA. Nature. 2016 Feb 25; 530(7591):441-6.
    View in: PubMed
    Score: 0.075
  73. N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency. Cell. 2015 Jun 04; 161(6):1388-99.
    View in: PubMed
    Score: 0.072
  74. Preparation of Human Nuclear RNA m6A Methyltransferases and Demethylases and Biochemical Characterization of Their Catalytic Activity. Methods Enzymol. 2015; 560:117-30.
    View in: PubMed
    Score: 0.071
  75. N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions. Nature. 2015 Feb 26; 518(7540):560-4.
    View in: PubMed
    Score: 0.070
  76. Dynamic RNA modifications in posttranscriptional regulation. Mol Cell. 2014 Oct 02; 56(1):5-12.
    View in: PubMed
    Score: 0.068
  77. FTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA. Nat Commun. 2013; 4:1798.
    View in: PubMed
    Score: 0.061
  78. ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. Mol Cell. 2013 Jan 10; 49(1):18-29.
    View in: PubMed
    Score: 0.060
  79. m6A RNA methylation modulates IFN-?-stimulated intestinal epithelial cell-intrinsic antiparasitic defense. PLoS Pathog. 2026 07; 22(7):e1014442.
    View in: PubMed
    Score: 0.039
  80. Arsenic regulates ALKBH1 abundance and substrate specificity to promote translation and tumorigenicity. Cell Rep. 2025 10 28; 44(10):116311.
    View in: PubMed
    Score: 0.037
  81. Dynamics of RNA localization to nuclear speckles are connected to splicing efficiency. Sci Adv. 2024 10 18; 10(42):eadp7727.
    View in: PubMed
    Score: 0.034
  82. RNA interacts with topoisomerase I to adjust DNA topology. Mol Cell. 2024 09 05; 84(17):3192-3208.e11.
    View in: PubMed
    Score: 0.034
  83. Light-induced LLPS of the CRY2/SPA1/FIO1 complex regulating mRNA methylation and chlorophyll homeostasis in Arabidopsis. Nat Plants. 2023 12; 9(12):2042-2058.
    View in: PubMed
    Score: 0.032
  84. O-GlcNAcylation determines the translational regulation and phase separation of YTHDF proteins. Nat Cell Biol. 2023 11; 25(11):1676-1690.
    View in: PubMed
    Score: 0.032
  85. CSTF2 mediated mRNA N6-methyladenosine modification drives pancreatic ductal adenocarcinoma m6A subtypes. Nat Commun. 2023 10 10; 14(1):6334.
    View in: PubMed
    Score: 0.032
  86. METTL14 is a chromatin regulator independent of its RNA N6-methyladenosine methyltransferase activity. Protein Cell. 2023 09 14; 14(9):683-697.
    View in: PubMed
    Score: 0.032
  87. A lncRNA from the FTO locus acts as a suppressor of the m6A writer complex and p53 tumor suppression signaling. Mol Cell. 2023 08 03; 83(15):2692-2708.e7.
    View in: PubMed
    Score: 0.031
  88. Globally reduced N6-methyladenosine (m6A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration. Nat Neurosci. 2023 08; 26(8):1328-1338.
    View in: PubMed
    Score: 0.031
  89. RBM33 is a unique m6A RNA-binding protein that regulates ALKBH5 demethylase activity and substrate selectivity. Mol Cell. 2023 06 15; 83(12):2003-2019.e6.
    View in: PubMed
    Score: 0.031
  90. METTL14 facilitates global genome repair and suppresses skin tumorigenesis. Proc Natl Acad Sci U S A. 2021 08 31; 118(35).
    View in: PubMed
    Score: 0.028
  91. Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis. Nat Commun. 2021 04 12; 12(1):2183.
    View in: PubMed
    Score: 0.027
  92. Control of Early B Cell Development by the RNA N6-Methyladenosine Methylation. Cell Rep. 2020 06 30; 31(13):107819.
    View in: PubMed
    Score: 0.025
  93. YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma. Mol Cancer. 2019 11 18; 18(1):163.
    View in: PubMed
    Score: 0.024
  94. FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export. Cell Rep. 2019 07 23; 28(4):845-854.e5.
    View in: PubMed
    Score: 0.024
  95. m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade. Nat Commun. 2019 06 25; 10(1):2782.
    View in: PubMed
    Score: 0.024
  96. Circadian Clock Regulation of Hepatic Lipid Metabolism by Modulation of m6A mRNA Methylation. Cell Rep. 2018 11 13; 25(7):1816-1828.e4.
    View in: PubMed
    Score: 0.023
  97. m6A facilitates hippocampus-dependent learning and memory through YTHDF1. Nature. 2018 11; 563(7730):249-253.
    View in: PubMed
    Score: 0.023
  98. METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification. Cell Stem Cell. 2018 02 01; 22(2):191-205.e9.
    View in: PubMed
    Score: 0.021
  99. ALKBH10B Is an RNA N6-Methyladenosine Demethylase Affecting Arabidopsis Floral Transition. Plant Cell. 2017 12; 29(12):2995-3011.
    View in: PubMed
    Score: 0.021
  100. m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells. Cell Rep. 2017 03 14; 18(11):2622-2634.
    View in: PubMed
    Score: 0.020
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.