"S100A12 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the S100 PROTEIN FAMILY that regulates INFLAMMATION and the immune response. It recruits LEUKOCYTES, promotes cytokine and chemokine production, and regulates leukocyte adhesion and migration. S100A12 can also function via binding to ADVANCED GLYCOSYLATION END PRODUCT-SPECIFIC RECEPTORS, to stimulate innate immune cells.
| Descriptor ID |
D000067616
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| MeSH Number(s) |
D12.776.157.125.750.875
|
| Concept/Terms |
S100A12 Protein- S100A12 Protein
- Protein, S100A12
- S100 A12 Protein
- A12 Protein, S100
- Protein, S100 A12
- MRP-6 Protein
- MRP 6 Protein
- Protein, MRP-6
- Calgranulin C Protein
- C Protein, Calgranulin
- Protein, Calgranulin C
- EN-RAGE Protein
- EN RAGE Protein
- Protein, EN-RAGE
- ENRAGE Protein
- Protein, ENRAGE
- S100A12
- CAAF1 Protein
- Protein, CAAF1
|
Below are MeSH descriptors whose meaning is more general than "S100A12 Protein".
Below are MeSH descriptors whose meaning is more specific than "S100A12 Protein".
This graph shows the total number of publications written about "S100A12 Protein" by people in this website by year, and whether "S100A12 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "S100A12 Protein" by people in Profiles.
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Serum S100A8/A9 and S100A12 Levels in Children With Polyarticular Forms of Juvenile Idiopathic Arthritis: Relationship to Maintenance of Clinically Inactive Disease During Anti-Tumor Necrosis Factor Therapy and Occurrence of Disease Flare After Discontinuation of Therapy. Arthritis Rheumatol. 2019 03; 71(3):451-459.
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S100/Calgranulin-mediated inflammation accelerates left ventricular hypertrophy and aortic valve sclerosis in chronic kidney disease in a receptor for advanced glycation end products-dependent manner. Arterioscler Thromb Vasc Biol. 2014 Jul; 34(7):1399-411.
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IL-22 is induced by S100/calgranulin and impairs cholesterol efflux in macrophages by downregulating ABCG1. J Lipid Res. 2014 Mar; 55(3):443-54.
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Beneficial effects of quinoline-3-carboxamide (ABR-215757) on atherosclerotic plaque morphology in S100A12 transgenic ApoE null mice. Atherosclerosis. 2013 May; 228(1):69-79.
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S100A12 expression in thoracic aortic aneurysm is associated with increased risk of dissection and perioperative complications. J Am Coll Cardiol. 2012 Aug 21; 60(8):775-85.
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Transgenic expression of human S100A12 induces structural airway abnormalities and limited lung inflammation in a mouse model of allergic inflammation. Clin Exp Allergy. 2011 Jun; 41(6):878-89.
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Vascular remodeling and arterial calcification are directly mediated by S100A12 (EN-RAGE) in chronic kidney disease. Am J Nephrol. 2011; 33(3):250-9.
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S100A12 in vascular smooth muscle accelerates vascular calcification in apolipoprotein E-null mice by activating an osteogenic gene regulatory program. Arterioscler Thromb Vasc Biol. 2011 Feb; 31(2):337-44.
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S100A12 mediates aortic wall remodeling and aortic aneurysm. Circ Res. 2010 Jan 08; 106(1):145-54.