"Lurasidone Hydrochloride" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A thiazole derivative and atypical ANTIPSYCHOTIC AGENT that functions as a DOPAMINE D2 RECEPTOR ANTAGONIST; SEROTONIN 5-HT2 RECEPTOR ANTAGONIST, serotonin 5-HT7 receptor antagonist, and antagonist of the adrenergic α2A and α2C receptors, as well as a partial SEROTONIN 5-HT1A RECEPTOR AGONIST. It is used in the treatment of SCHIZOPHRENIA and BIPOLAR DISORDER.
| Descriptor ID |
D000069056
|
| MeSH Number(s) |
D02.886.675.414 D03.383.129.708.414 D03.633.100.513.437
|
| Concept/Terms |
SM 13496- SM 13496
- 13496, SM
- SM13496
- SM-13,496
- SM 13,496
- SM13,496
- SM-13496
Lurasidone- Lurasidone
- N-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinylmethyl)-1-cyclohexylmethyl)-2,3-bicyclo(2.2.1)heptanedicarboximide
|
Below are MeSH descriptors whose meaning is more general than "Lurasidone Hydrochloride".
Below are MeSH descriptors whose meaning is more specific than "Lurasidone Hydrochloride".
This graph shows the total number of publications written about "Lurasidone Hydrochloride" by people in this website by year, and whether "Lurasidone Hydrochloride" was a major or minor topic of these publications.
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Below are the most recent publications written about "Lurasidone Hydrochloride" by people in Profiles.
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Muscarinic receptor signaling contributes to atypical antipsychotic drug reversal of the phencyclidine-induced deficit in novel object recognition in rats. J Psychopharmacol. 2017 12; 31(12):1588-1604.
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Dopamine D4 receptor stimulation contributes to novel object recognition: Relevance to cognitive impairment in schizophrenia. J Psychopharmacol. 2017 04; 31(4):442-452.
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Nicotinic receptors and lurasidone-mediated reversal of phencyclidine-induced deficit in novel object recognition. Behav Brain Res. 2016 Mar 15; 301:204-12.
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Prolonged reversal of the phencyclidine-induced impairment in novel object recognition by a serotonin (5-HT)1A-dependent mechanism. Behav Brain Res. 2016 Mar 15; 301:132-41.