"Pregabalin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A gamma-aminobutyric acid (GABA) derivative that functions as a CALCIUM CHANNEL BLOCKER and is used as an ANTICONVULSANT as well as an ANTI-ANXIETY AGENT. It is also used as an ANALGESIC in the treatment of NEUROPATHIC PAIN and FIBROMYALGIA.
| Descriptor ID |
D000069583
|
| MeSH Number(s) |
D02.241.081.114.500.350.500 D12.125.190.350.450
|
| Concept/Terms |
Pregabalin- Pregabalin
- (S)-3-(aminomethyl)-5-methylhexanoic acid
- 3-isobutyl GABA
- 3 isobutyl GABA
- GABA, 3-isobutyl
- 3-(aminomethyl)-5-methylhexanoic acid
- (R-)-3-isobutyl GABA
- (S+)-3-isobutyl GABA
CI 1008- CI 1008
- 1008, CI
- CI-1008
- CI1008
|
Below are MeSH descriptors whose meaning is more general than "Pregabalin".
Below are MeSH descriptors whose meaning is more specific than "Pregabalin".
This graph shows the total number of publications written about "Pregabalin" by people in this website by year, and whether "Pregabalin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pregabalin" by people in Profiles.
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Pregabalin for Recurrent Seizures in Critical Illness: A Promising Adjunctive Therapy, Especially for cyclic Seizures. Neurocrit Care. 2022 08; 37(1):140-148.
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Pregabalin adjunctive therapy for focal onset seizures in children 1 month to <4 years of age: A double-blind, placebo-controlled, video-electroencephalographic trial. Epilepsia. 2020 04; 61(4):617-626.
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Pregabalin as Adjunctive Treatment for Focal Onset Seizures in Pediatric Patients: A Randomized Controlled Trial. J Child Neurol. 2019 04; 34(5):248-255.
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Randomised phase II trial (NCT00637975) evaluating activity and toxicity of two different escalating strategies for pregabalin and oxycodone combination therapy for neuropathic pain in cancer patients. PLoS One. 2013; 8(4):e59981.
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Subjective, psychomotor, and physiological effects of pregabalin alone and in combination with oxycodone in healthy volunteers. Pharmacol Biochem Behav. 2012 Jan; 100(3):560-5.
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Efficacy of pregabalin in generalized social anxiety disorder: results of a double-blind, placebo-controlled, fixed-dose study. Int Clin Psychopharmacol. 2011 Jul; 26(4):213-20.
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Pregabalin for treatment of generalized anxiety disorder: a 4-week, multicenter, double-blind, placebo-controlled trial of pregabalin and alprazolam. Arch Gen Psychiatry. 2005 Sep; 62(9):1022-30.
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Pregabalin in generalized anxiety disorder: a placebo-controlled trial. Am J Psychiatry. 2003 Mar; 160(3):533-40.