Stromal Interaction Molecule 1
"Stromal Interaction Molecule 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A stromal interaction molecule that functions in the regulation of calcium influx following depletion of intracellular calcium in the ENDOPLASMIC RETICULUM. It translocates to the plasma membrane upon calcium depletion where it activates the CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL ORAI1.
| Descriptor ID |
D000071737
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| MeSH Number(s) |
D12.776.157.125.806.500 D12.776.543.875.500
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Stromal Interaction Molecule 1".
Below are MeSH descriptors whose meaning is more specific than "Stromal Interaction Molecule 1".
This graph shows the total number of publications written about "Stromal Interaction Molecule 1" by people in this website by year, and whether "Stromal Interaction Molecule 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Stromal Interaction Molecule 1" by people in Profiles.
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STIM1-mediated calcium influx controls antifungal immunity and the metabolic function of non-pathogenic Th17 cells. EMBO Mol Med. 2020 08 07; 12(8):e11592.
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Store-operated Ca2+ entry regulates Ca2+-activated chloride channels and eccrine sweat gland function. J Clin Invest. 2016 11 01; 126(11):4303-4318.
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Dental enamel cells express functional SOCE channels. Sci Rep. 2015 Oct 30; 5:15803.
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Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells. J Immunol. 2015 Aug 01; 195(3):1202-17.
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Ca2+ influx through store-operated Ca2+ channels reduces Alzheimer disease ß-amyloid peptide secretion. J Biol Chem. 2013 Sep 13; 288(37):26955-66.
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Stanniocalcin 2 is a negative modulator of store-operated calcium entry. Mol Cell Biol. 2011 Sep; 31(18):3710-22.
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Hypoxia leads to Na,K-ATPase downregulation via Ca(2+) release-activated Ca(2+) channels and AMPK activation. Mol Cell Biol. 2011 Sep; 31(17):3546-56.
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Hypoxia triggers AMPK activation through reactive oxygen species-mediated activation of calcium release-activated calcium channels. Mol Cell Biol. 2011 Sep; 31(17):3531-45.
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Reversible translocation of EYFP-tagged STIM1 is coupled to calcium influx in insulin secreting beta-cells. Cell Calcium. 2008 Dec; 44(6):533-44.