"Perilipin-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A perilipin that is expressed by many different cell types. It binds FATTY ACIDS and CHOLESTEROL, stabilizes TRIGLYCERIDES, and localizes to both the surface and hydrophobic core of LIPID DROPLETS, as well as the ENDOPLASMIC RECTICULUM and PLASMA MEMBRANE in MACROPHAGES. It also plays a central role in the biogenesis of lipid droplets and FOAM CELLS and is highly expressed by macrophages at atherosclerotic lesions in human arteries along with the INFLAMMATION markers TNF-ALPHA; MCP-1 RECEPTOR; and IL-6.
| Descriptor ID |
D000070780
|
| MeSH Number(s) |
D12.776.157.464.500.750
|
| Concept/Terms |
Perilipin-2- Perilipin-2
- Perilipin 2
- ADRP Protein
- Adipose Differentiation-Related Protein
- Adipose Differentiation Related Protein
- Protein, Adipose Differentiation-Related
- PLIN2 Protein
- Protein, PLIN2
- Perilipin 2 Protein
- Protein, Perilipin 2
- Adipophilin
|
Below are MeSH descriptors whose meaning is more general than "Perilipin-2".
Below are MeSH descriptors whose meaning is more specific than "Perilipin-2".
This graph shows the total number of publications written about "Perilipin-2" by people in this website by year, and whether "Perilipin-2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Perilipin-2" by people in Profiles.
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FOXO3 growth inhibition of colonic cells is dependent on intraepithelial lipid droplet density. J Biol Chem. 2013 Jun 07; 288(23):16274-16281.
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Identification of high and low responders to lipopolysaccharide in normal subjects: an unbiased approach to identify modulators of innate immunity. J Immunol. 2005 Aug 15; 175(4):2570-8.