Pancreatitis-Associated Proteins
"Pancreatitis-Associated Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
C-type lectins that restrict growth of bacteria in the intestinal epithelia and have bactericidal activity against gram-positive and gram-negative bacteria. They also regulate proliferation and differentiation of KERATINOCYTES following injury. Human pancreatitis-associated protein-1 (Reg3a) is overexpressed by pancreatic ACINAR CELLS in patients with CHRONIC PANCREATITIS. It is also highly expressed by pancreatic, bladder, and gastrointestinal cancer cells and may serve as a diagnostic biomarker.
Descriptor ID |
D000073718
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MeSH Number(s) |
D12.776.503.280.578 D23.050.285.733 D23.101.140.780
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Concept/Terms |
Pancreatitis-Associated Proteins- Pancreatitis-Associated Proteins
- Pancreatitis Associated Proteins
- Regenerating Islet-Derived Proteins
- Regenerating Islet Derived Proteins
Pancreatitis-Associated Protein-1- Pancreatitis-Associated Protein-1
- Pancreatitis Associated Protein 1
- Pancreatitis-Associated Protein
- Pancreatitis Associated Protein
- Regenerating Islet-Derived Protein 3
- Regenerating Islet Derived Protein 3
|
Below are MeSH descriptors whose meaning is more general than "Pancreatitis-Associated Proteins".
Below are MeSH descriptors whose meaning is more specific than "Pancreatitis-Associated Proteins".
This graph shows the total number of publications written about "Pancreatitis-Associated Proteins" by people in this website by year, and whether "Pancreatitis-Associated Proteins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2006 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2009 | 0 | 2 | 2 |
2010 | 0 | 1 | 1 |
2012 | 0 | 2 | 2 |
2014 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
2017 | 0 | 2 | 2 |
2019 | 0 | 1 | 1 |
2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pancreatitis-Associated Proteins" by people in Profiles.
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Deep Crypt Secretory Cell Differentiation in the Colonic Epithelium Is Regulated by Sprouty2 and Interleukin 13. Cell Mol Gastroenterol Hepatol. 2023; 15(4):971-984.
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METTL14 is essential for ß-cell survival and insulin secretion. Biochim Biophys Acta Mol Basis Dis. 2019 09 01; 1865(9):2138-2148.
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Comparative quantitative proteomic analysis of disease stratified laser captured microdissected human islets identifies proteins and pathways potentially related to type 1 diabetes. PLoS One. 2017; 12(9):e0183908.
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Neonatal acquisition of Clostridia species protects against colonization by bacterial pathogens. Science. 2017 04 21; 356(6335):315-319.
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TLR-7 activation enhances IL-22-mediated colonization resistance against vancomycin-resistant enterococcus. Sci Transl Med. 2016 Feb 24; 8(327):327ra25.
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Intestinal epithelial expression of TNFAIP3 results in microbial invasion of the inner mucus layer and induces colitis in IL-10-deficient mice. Am J Physiol Gastrointest Liver Physiol. 2014 Nov 01; 307(9):G871-82.
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The enteric nervous system neuropeptide, bombesin, reverses innate immune impairments during parenteral nutrition. Ann Surg. 2014 Sep; 260(3):432-43; discussion 443-4.
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Parenteral nutrition decreases paneth cell function and intestinal bactericidal activity while increasing susceptibility to bacterial enteroinvasion. JPEN J Parenter Enteral Nutr. 2014 Sep; 38(7):817-824.
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Targeted deletion of MyD88 in intestinal epithelial cells results in compromised antibacterial immunity associated with downregulation of polymeric immunoglobulin receptor, mucin-2, and antibacterial peptides. Mucosal Immunol. 2012 Sep; 5(5):501-12.
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Interleukin 23 production by intestinal CD103(+)CD11b(+) dendritic cells in response to bacterial flagellin enhances mucosal innate immune defense. Immunity. 2012 Feb 24; 36(2):276-87.