Immunoglobulin Light-chain Amyloidosis
"Immunoglobulin Light-chain Amyloidosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nonproliferative disorder of the PLASMA CELL characterized by excessive production and misfolding of IMMUNOGLOBULIN LIGHT CHAINS that form insoluble amyloid fibrils (see AMYLOID DEPOSITS) in various tissues. Clinical features include LIVER FAILURE; MULTIPLE MYELOMA; NEPHROTIC SYNDROME; RESTRICTIVE CARDIOMYOPATHY, and neuropathies.
| Descriptor ID |
D000075363
|
| MeSH Number(s) |
C04.557.595.250 C18.452.845.500.550 C20.683.515.507 C20.683.780.565
|
| Concept/Terms |
Immunoglobulin Light-chain Amyloidosis- Immunoglobulin Light-chain Amyloidosis
- Immunoglobulin Light chain Amyloidosis
- Immunoglobulin Light-chain Amyloidoses
- Amyloidosis, Primary
- AL Amyloidosis
- AL Amyloidoses
- Primary Systemic Amyloidosis
- Amyloidoses, Primary Systemic
- Amyloidosis, Primary Systemic
- Primary Systemic Amyloidoses
- Systemic Amyloidoses, Primary
- Systemic Amyloidosis, Primary
- Amyloidosis, Immunoglobulin Light-chain
- Amyloidosis, Immunoglobulin Light chain
- Primary Amyloidosis
- Amyloidoses, Primary
- Primary Amyloidoses
|
Below are MeSH descriptors whose meaning is more general than "Immunoglobulin Light-chain Amyloidosis".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin Light-chain Amyloidosis".
This graph shows the total number of publications written about "Immunoglobulin Light-chain Amyloidosis" by people in this website by year, and whether "Immunoglobulin Light-chain Amyloidosis" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 3 | 0 | 3 |
| 2021 | 1 | 0 | 1 |
| 2022 | 3 | 0 | 3 |
| 2023 | 1 | 0 | 1 |
| 2024 | 1 | 2 | 3 |
| 2025 | 1 | 0 | 1 |
| 2026 | 4 | 1 | 5 |
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Below are the most recent publications written about "Immunoglobulin Light-chain Amyloidosis" by people in Profiles.
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Diagnostic utility of immunofixation and free light chain assay in AL amyloidosis: a systematic review and meta-analysis. Blood Adv. 2026 Aug 11; 10(15):5293-5307.
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American Society of Hematology 2026 guidelines on diagnosis of light chain amyloidosis. Blood Adv. 2026 Jul 28; 10(14):5113-5152.
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Clinical features of systemic amyloidosis: a scoping review. Blood Adv. 2026 Jul 28; 10(14):5097-5112.
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Multimodal Artificial Intelligence for Cardiac Amyloidosis Diagnosis: Integrating Echocardiography With Clinical and Laboratory Data for Improved Detection. Circ Cardiovasc Imaging. 2026 Jun; 19(6):e019610.
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The role of cardiac imaging for diagnosis of cardiac amyloidosis: a systematic review and meta-analysis of test accuracy. Amyloid. 2026 Mar; 33(1):59-71.
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Changing lanes: extending CAR T-cell therapy to high-risk plasma cell dyscrasias. Front Immunol. 2025; 16:1558275.
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Evaluation of administration-related reactions with subcutaneous daratumumab with and without premedication. Oncologist. 2024 Sep 06; 29(9):806-810.
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Perivascular Amyloid Deposition in Immunoglobulin Light Chain Cardiac Amyloidosis and Its Implications on Echocardiographic Cardiac Remodeling. J Am Soc Echocardiogr. 2024 Oct; 37(10):1010-1012.
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Defining echocardiographic predictors of outcome in cardiac amyloidosis by subtype. Curr Probl Cardiol. 2024 Sep; 49(9):102729.
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Vascular Amyloid Deposition Is Highly Prevalent in Immunoglobulin Light Chain Cardiac Amyloidosis. JACC Cardiovasc Imaging. 2023 08; 16(8):1121-1123.