"Anoctamins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of transmembrane proteins that function primarily as calcium-activated chloride channels. Structurally, they form a homodimer where each subunit consists of eight transmembrane helices with the N and C terminals exposed to the cytosol. The regions between helices 5 and 7 may be important for ion pore formation and calcium ion binding.
| Descriptor ID |
D000075368
|
| MeSH Number(s) |
D12.776.157.530.400.175.032 D12.776.543.550.450.175.032 D12.776.543.585.400.175.032
|
| Concept/Terms |
Anoctamins- Anoctamins
- Anoctamin
- TMEM16 Protein Family
- Protein Family, TMEM16
- TMEM16 Proteins
|
Below are MeSH descriptors whose meaning is more general than "Anoctamins".
Below are MeSH descriptors whose meaning is more specific than "Anoctamins".
This graph shows the total number of publications written about "Anoctamins" by people in this website by year, and whether "Anoctamins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Anoctamins" by people in Profiles.
-
Eight new mutations and the expanding phenotype variability in muscular dystrophy caused by ANO5. Neurology. 2012 Mar 20; 78(12):897-903.