MEF2 Transcription Factors
"MEF2 Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Activating transcription factors of the MADS family which bind a specific sequence element (MEF2 element) in many muscle-specific genes and are involved in skeletal and cardiac myogenesis, neuronal differentiation and survival/apoptosis.
Descriptor ID |
D064326
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MeSH Number(s) |
D12.776.210.500.570.294 D12.776.260.103.750.294 D12.776.260.400.249.624 D12.776.930.125.750.294 D12.776.930.397.700
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Concept/Terms |
MEF2 Transcription Factors- MEF2 Transcription Factors
- Transcription Factors, MEF2
- Muscle Enhancer Factor-2
- Enhancer Factor-2, Muscle
- Muscle Enhancer Factor 2
- Myocyte-Specific Enhancer-Binding Factor 2
- Myocyte Specific Enhancer Binding Factor 2
- Myocyte Enhancer Factor 2
- Myocyte-Specific Enhancer Factor 2
- Myocyte Specific Enhancer Factor 2
- MEF2 Proteins
- Muscle-Specific Enhancer Factor-2
- Enhancer Factor-2, Muscle-Specific
- Muscle Specific Enhancer Factor 2
MEF2B Transcription Factor- MEF2B Transcription Factor
- Transcription Factor, MEF2B
- Serum Response Factor-Like Protein 2
- Serum Response Factor Like Protein 2
- Myocyte-Specific Enhancer Factor 2B
- Myocyte Specific Enhancer Factor 2B
- Muscle Enhancer Factor-2B
- Enhancer Factor-2B, Muscle
- Muscle Enhancer Factor 2B
- Muscle-Specific Enhancer Factor-2B
- Enhancer Factor-2B, Muscle-Specific
- Muscle Specific Enhancer Factor 2B
- Myocyte Enhancer Factor 2B
- Myocyte-Specific Enhancer-Binding Factor 2B
- Myocyte Specific Enhancer Binding Factor 2B
- MEF2B Protein
MEF2D Transcription Factor- MEF2D Transcription Factor
- Transcription Factor, MEF2D
- Muscle Enhancer Factor-2D
- Enhancer Factor-2D, Muscle
- Muscle Enhancer Factor 2D
- Muscle-Specific Enhancer Factor-2D
- Enhancer Factor-2D, Muscle-Specific
- Muscle Specific Enhancer Factor 2D
- Myocyte-Specific Enhancer Factor 2D
- Myocyte Specific Enhancer Factor 2D
- Myocyte-Specific Enhancer-Binding Factor 2D
- Myocyte Specific Enhancer Binding Factor 2D
- MEF2D Protein
- Myocyte Enhancer Factor 2D
MEF2A Transcription Factor- MEF2A Transcription Factor
- Transcription Factor, MEF2A
- Muscle Enhancer Factor-2A
- Enhancer Factor-2A, Muscle
- Muscle Enhancer Factor 2A
- Serum Response Factor-Like Protein 1
- Serum Response Factor Like Protein 1
- Myocyte Enhancer Factor 2A
- Myocyte-Specific Enhancer Factor 2A
- Myocyte Specific Enhancer Factor 2A
- Myocyte-Specific Enhancer-Binding Factor 2A
- Myocyte Specific Enhancer Binding Factor 2A
- MEF2A Protein
- Muscle-Specific Enhancer Factor-2A
- Enhancer Factor-2A, Muscle-Specific
- Muscle Specific Enhancer Factor 2A
MEF2C Transcription Factor- MEF2C Transcription Factor
- Transcription Factor, MEF2C
- Muscle Enhancer Factor-2C
- Enhancer Factor-2C, Muscle
- Muscle Enhancer Factor 2C
- Myocyte-Specific Enhancer-Binding Factor 2C
- Myocyte Specific Enhancer Binding Factor 2C
- Myocyte Enhancer Factor 2C
- Myocyte-Specific Enhancer Factor 2C
- Myocyte Specific Enhancer Factor 2C
- MEF2C Protein
- Muscle-Specific Enhancer Factor-2C
- Enhancer Factor-2C, Muscle-Specific
- Muscle Specific Enhancer Factor 2C
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Below are MeSH descriptors whose meaning is more general than "MEF2 Transcription Factors".
Below are MeSH descriptors whose meaning is more specific than "MEF2 Transcription Factors".
This graph shows the total number of publications written about "MEF2 Transcription Factors" by people in this website by year, and whether "MEF2 Transcription Factors" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
2016 | 0 | 2 | 2 |
2017 | 0 | 1 | 1 |
2018 | 0 | 1 | 1 |
2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "MEF2 Transcription Factors" by people in Profiles.
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Pulsed glucocorticoids enhance dystrophic muscle performance through epigenetic-metabolic reprogramming. JCI Insight. 2019 12 19; 4(24).
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Hypercapnia increases airway smooth muscle contractility via caspase-7-mediated miR-133a-RhoA signaling. Sci Transl Med. 2018 09 05; 10(457).
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Genome-Wide Association Study to Find Modifiers for Tetralogy of Fallot in the 22q11.2 Deletion Syndrome Identifies Variants in the GPR98 Locus on 5q14.3. Circ Cardiovasc Genet. 2017 Oct; 10(5).
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MiR-590 Promotes Transdifferentiation of Porcine and Human Fibroblasts Toward a Cardiomyocyte-Like Fate by Directly Repressing Specificity Protein 1. J Am Heart Assoc. 2016 11 10; 5(11).
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Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia. Nat Commun. 2016 11 08; 7:13331.
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MEF2C Haploinsufficiency features consistent hyperkinesis, variable epilepsy, and has a role in dorsal and ventral neuronal developmental pathways. Neurogenetics. 2013 May; 14(2):99-111.
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Developmentally regulated expression of MEF2C limits the response to BCR engagement in transitional B cells. Eur J Immunol. 2012 May; 42(5):1327-36.
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Dephosphorylation and caspase processing generate distinct nuclear pools of histone deacetylase 4. Mol Cell Biol. 2007 Oct; 27(19):6718-32.
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TEF-1 and MEF2 transcription factors interact to regulate muscle-specific promoters. Biochem Biophys Res Commun. 2002 Jun 21; 294(4):791-7.
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Mef2 proteins, required for muscle differentiation, bind an essential site in the Ig lambda enhancer. J Immunol. 1998 Nov 01; 161(9):4795-802.