"Meprobamate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603)
| Descriptor ID |
D008620
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| MeSH Number(s) |
D02.241.081.251.510
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Meprobamate".
Below are MeSH descriptors whose meaning is more specific than "Meprobamate".
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Below are the most recent publications written about "Meprobamate" by people in Profiles.
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Quantitative EEG analysis of single-dose effect relationships in normal volunteers of Pacinox (capuride), a new antianxiety drug. Biol Psychiatry. 1971; 3(2):165-72.
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TIME-SERIES, FREQUENCY ANALYSIS, AND ELECTROGENESIS OF THE EEGS OF NORMALS AND PSYCHOTICS BEFORE AND AFTER DRUGS. Am J Psychiatry. 1965 Jun; 121:1147-55.
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PANEL DISCUSSION. 3. THE FUTURE OF TRANQUILIZER RESEARCH AND THE THERAPY OF ANXIETY. ASSAY OF ANTI-ANXIETY DRUGS BY QUANTITATIVE ELECTROENCEPHALOGRAPHY. J Neuropsychiatr. 1964 Oct; 5:475-86.