"Mucopolysaccharidosis II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Systemic lysosomal storage disease marked by progressive physical deterioration and caused by a deficiency of L-sulfoiduronate sulfatase. This disease differs from MUCOPOLYSACCHARIDOSIS I by slower progression, lack of corneal clouding, and X-linked rather than autosomal recessive inheritance. The mild form produces near-normal intelligence and life span. The severe form usually causes death by age 15.
| Descriptor ID |
D016532
|
| MeSH Number(s) |
C10.597.606.643.455.750 C16.320.322.500.750 C16.320.400.525.750 C16.320.565.202.715.645 C16.320.565.595.600.645 C17.300.550.575.645 C18.452.648.202.715.645 C18.452.648.595.600.645
|
| Concept/Terms |
Mucopolysaccharidosis II- Mucopolysaccharidosis II
- Hunter Syndrome Gargoylism
- Hunter's Syndrome
- Hunters Syndrome
- Syndrome, Hunter's
- Mucopolysaccharidosis Type 2
- Mucopolysaccharidosis Type II
- Hunter Syndrome
- Syndrome, Hunter
- Gargoylism, Hunter Syndrome
- Mucopolysaccharidosis 2
Sulfoiduronate Sulfatase Deficiency- Sulfoiduronate Sulfatase Deficiency
- Deficiency, Sulfoiduronate Sulfatase
- Iduronate Sulfatase Deficiency
- Deficiency, Iduronate Sulfatase
- I2S Deficiency
- Deficiency, I2S
- Iduronate 2-Sulfatase Deficiency
- Deficiency, Iduronate 2-Sulfatase
- Iduronate 2 Sulfatase Deficiency
|
Below are MeSH descriptors whose meaning is more general than "Mucopolysaccharidosis II".
- Diseases [C]
- Nervous System Diseases [C10]
- Neurologic Manifestations [C10.597]
- Neurobehavioral Manifestations [C10.597.606]
- Intellectual Disability [C10.597.606.643]
- Mental Retardation, X-Linked [C10.597.606.643.455]
- Mucopolysaccharidosis II [C10.597.606.643.455.750]
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
- Genetic Diseases, X-Linked [C16.320.322]
- Mental Retardation, X-Linked [C16.320.322.500]
- Mucopolysaccharidosis II [C16.320.322.500.750]
- Heredodegenerative Disorders, Nervous System [C16.320.400]
- Mental Retardation, X-Linked [C16.320.400.525]
- Mucopolysaccharidosis II [C16.320.400.525.750]
- Metabolism, Inborn Errors [C16.320.565]
- Carbohydrate Metabolism, Inborn Errors [C16.320.565.202]
- Mucopolysaccharidoses [C16.320.565.202.715]
- Mucopolysaccharidosis II [C16.320.565.202.715.645]
- Lysosomal Storage Diseases [C16.320.565.595]
- Mucopolysaccharidoses [C16.320.565.595.600]
- Mucopolysaccharidosis II [C16.320.565.595.600.645]
- Skin and Connective Tissue Diseases [C17]
- Connective Tissue Diseases [C17.300]
- Mucinoses [C17.300.550]
- Mucopolysaccharidoses [C17.300.550.575]
- Mucopolysaccharidosis II [C17.300.550.575.645]
- Nutritional and Metabolic Diseases [C18]
- Metabolic Diseases [C18.452]
- Metabolism, Inborn Errors [C18.452.648]
- Carbohydrate Metabolism, Inborn Errors [C18.452.648.202]
- Mucopolysaccharidoses [C18.452.648.202.715]
- Mucopolysaccharidosis II [C18.452.648.202.715.645]
- Lysosomal Storage Diseases [C18.452.648.595]
- Mucopolysaccharidoses [C18.452.648.595.600]
- Mucopolysaccharidosis II [C18.452.648.595.600.645]
Below are MeSH descriptors whose meaning is more specific than "Mucopolysaccharidosis II".
This graph shows the total number of publications written about "Mucopolysaccharidosis II" by people in this website by year, and whether "Mucopolysaccharidosis II" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Mucopolysaccharidosis II" by people in Profiles.
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Hunter syndrome with late age of presentation: clinical description of a case and review of the literature. BMJ Case Rep. 2015 May 14; 2015.
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LCR-initiated rearrangements at the IDS locus, completed with Alu-mediated recombination or non-homologous end joining. J Hum Genet. 2011 Jul; 56(7):516-23.
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Natural history of extensive Mongolian spots in mucopolysaccharidosis type II (Hunter syndrome): a survey among 52 Japanese patients. J Eur Acad Dermatol Venereol. 2007 Sep; 21(8):1082-5.
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Hunter disease (mucopolysaccharidosis type II) in a karyotypically normal girl. Clin Genet. 1990 May; 37(5):355-62.
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Inguinal hernia in the Hurler-Hunter syndrome. Surgery. 1967 Feb; 61(2):302-4.