Bernard Roizman to Animals
This is a "connection" page, showing publications Bernard Roizman has written about Animals.
Connection Strength
1.380
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The Story behind the Science: On the discovery of respiratory syncytial virus. mBio. 2025 Mar 12; 16(3):e0307424.
Score: 0.056
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The SP100 component of ND10 enhances accumulation of PML and suppresses replication and the assembly of HSV replication compartments. Proc Natl Acad Sci U S A. 2017 05 09; 114(19):E3823-E3829.
Score: 0.033
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PML plays both inimical and beneficial roles in HSV-1 replication. Proc Natl Acad Sci U S A. 2016 May 24; 113(21):E3022-8.
Score: 0.031
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Role of activating transcription factor 3 in the synthesis of latency-associated transcript and maintenance of herpes simplex virus 1 in latent state in ganglia. Proc Natl Acad Sci U S A. 2015 Sep 29; 112(39):E5420-6.
Score: 0.029
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Patterns of accumulation of miRNAs encoded by herpes simplex virus during productive infection, latency, and on reactivation. Proc Natl Acad Sci U S A. 2015 Jan 06; 112(1):E49-55.
Score: 0.028
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Cells infected with herpes simplex virus 1 export to uninfected cells exosomes containing STING, viral mRNAs, and microRNAs. Proc Natl Acad Sci U S A. 2014 Nov 18; 111(46):E4991-6.
Score: 0.028
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The stability of herpes simplex virus 1 ICP0 early after infection is defined by the RING finger and the UL13 protein kinase. J Virol. 2014 May; 88(10):5437-43.
Score: 0.026
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HSV-1 degrades, stabilizes, requires, or is stung by STING depending on ICP0, the US3 protein kinase, and cell derivation. Proc Natl Acad Sci U S A. 2014 Feb 04; 111(5):E611-7.
Score: 0.026
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Selective degradation of mRNAs by the HSV host shutoff RNase is regulated by the UL47 tegument protein. Proc Natl Acad Sci U S A. 2013 Apr 30; 110(18):E1669-75.
Score: 0.025
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The herpes simplex virus host shutoff RNase degrades cellular and viral mRNAs made before infection but not viral mRNA made after infection. J Virol. 2013 Apr; 87(8):4516-22.
Score: 0.025
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HSV carrying WT REST establishes latency but reactivates only if the synthesis of REST is suppressed. Proc Natl Acad Sci U S A. 2013 Feb 05; 110(6):E498-506.
Score: 0.025
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The virion host shutoff RNase plays a key role in blocking the activation of protein kinase R in cells infected with herpes simplex virus 1. J Virol. 2013 Mar; 87(6):3271-6.
Score: 0.024
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An inquiry into the molecular basis of HSV latency and reactivation. Annu Rev Microbiol. 2013; 67:355-74.
Score: 0.024
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Overexpression of the ubiquitin-specific protease 7 resulting from transfection or mutations in the ICP0 binding site accelerates rather than depresses herpes simplex virus 1 gene expression. J Virol. 2012 Dec; 86(23):12871-8.
Score: 0.024
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Induction of apoptosis accelerates reactivation of latent HSV-1 in ganglionic organ cultures and replication in cell cultures. Proc Natl Acad Sci U S A. 2012 Sep 04; 109(36):14616-21.
Score: 0.024
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HSV-1 gene expression from reactivated ganglia is disordered and concurrent with suppression of latency-associated transcript and miRNAs. Proc Natl Acad Sci U S A. 2011 Nov 15; 108(46):18820-4.
Score: 0.023
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Checkpoints in productive and latent infections with herpes simplex virus 1: conceptualization of the issues. J Neurovirol. 2011 Dec; 17(6):512-7.
Score: 0.023
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The checkpoints of viral gene expression in productive and latent infection: the role of the HDAC/CoREST/LSD1/REST repressor complex. J Virol. 2011 Aug; 85(15):7474-82.
Score: 0.022
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Circadian CLOCK histone acetyl transferase localizes at ND10 nuclear bodies and enables herpes simplex virus gene expression. Proc Natl Acad Sci U S A. 2010 Oct 12; 107(41):17721-6.
Score: 0.021
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Interwoven roles of cyclin D3 and cdk4 recruited by ICP0 and ICP4 in the expression of herpes simplex virus genes. J Virol. 2010 Oct; 84(19):9709-17.
Score: 0.021
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Role of herpes simplex virus ICP27 in the degradation of mRNA by virion host shutoff RNase. J Virol. 2010 Oct; 84(19):10182-90.
Score: 0.021
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The novel HSV-1 US5-1 RNA is transcribed off a domain encoding US5, US4, US3, US2 and alpha22. Virol J. 2010 May 21; 7:103.
Score: 0.020
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Role of herpes simplex virus ICP0 in the transactivation of genes introduced by infection or transfection: a reappraisal. J Virol. 2010 May; 84(9):4222-8.
Score: 0.020
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ICP0 enables and monitors the function of D cyclins in herpes simplex virus 1 infected cells. Proc Natl Acad Sci U S A. 2009 Aug 25; 106(34):14576-80.
Score: 0.019
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Nuclear retention of ICP0 in cells exposed to HDAC inhibitor or transfected with DNA before infection with herpes simplex virus 1. Proc Natl Acad Sci U S A. 2008 Dec 23; 105(51):20488-93.
Score: 0.018
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The two functions of herpes simplex virus 1 ICP0, inhibition of silencing by the CoREST/REST/HDAC complex and degradation of PML, are executed in tandem. J Virol. 2009 Jan; 83(1):181-7.
Score: 0.018
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The interaction of herpes simplex virus 1 regulatory protein ICP22 with the cdc25C phosphatase is enabled in vitro by viral protein kinases US3 and UL13. J Virol. 2008 May; 82(9):4533-43.
Score: 0.017
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Role of cellular phosphatase cdc25C in herpes simplex virus 1 replication. J Virol. 2008 May; 82(9):4527-32.
Score: 0.017
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Proteolytic cleavage of VP1-2 is required for release of herpes simplex virus 1 DNA into the nucleus. J Virol. 2008 Apr; 82(7):3311-9.
Score: 0.017
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Herpes simplex virus-infected cell protein 0 blocks the silencing of viral DNA by dissociating histone deacetylases from the CoREST-REST complex. Proc Natl Acad Sci U S A. 2007 Oct 23; 104(43):17134-9.
Score: 0.017
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In transduced cells, the US3 protein kinase of herpes simplex virus 1 precludes activation and induction of apoptosis by transfected procaspase 3. J Virol. 2007 Oct; 81(19):10242-8.
Score: 0.017
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Attenuated herpes simplex virus 1 blocks arterial apoptosis and intimal hyperplasia induced by balloon angioplasty and reduced blood flow. Proc Natl Acad Sci U S A. 2007 Jul 24; 104(30):12474-8.
Score: 0.017
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Separation of receptor-binding and profusogenic domains of glycoprotein D of herpes simplex virus 1 into distinct interacting proteins. Proc Natl Acad Sci U S A. 2007 Mar 06; 104(10):4142-6.
Score: 0.016
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Mapping of key functions of the herpes simplex virus 1 U(S)3 protein kinase: the U(S)3 protein can form functional heteromultimeric structures derived from overlapping truncated polypeptides. J Virol. 2007 Feb; 81(4):1980-9.
Score: 0.016
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The egress of herpesviruses from cells: the unanswered questions. J Virol. 2006 Jul; 80(13):6716-7; author replies 6717-9.
Score: 0.016
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ICP0 and the US3 protein kinase of herpes simplex virus 1 independently block histone deacetylation to enable gene expression. Proc Natl Acad Sci U S A. 2006 Jun 27; 103(26):9993-8.
Score: 0.016
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State and role of SRC family kinases in replication of herpes simplex virus 1. J Virol. 2006 Apr; 80(7):3349-59.
Score: 0.015
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U(S)3 and U(S)3.5 protein kinases of herpes simplex virus 1 differ with respect to their functions in blocking apoptosis and in virion maturation and egress. J Virol. 2006 Apr; 80(8):3752-64.
Score: 0.015
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Construction and properties of a herpes simplex virus 1 designed to enter cells solely via the IL-13alpha2 receptor. Proc Natl Acad Sci U S A. 2006 Apr 04; 103(14):5508-13.
Score: 0.015
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Herpes simplex virus 1 ICP22 regulates the accumulation of a shorter mRNA and of a truncated US3 protein kinase that exhibits altered functions. J Virol. 2005 Jul; 79(13):8470-9.
Score: 0.015
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Characterization of a recombinant herpes simplex virus 1 designed to enter cells via the IL13Ralpha2 receptor of malignant glioma cells. J Virol. 2005 May; 79(9):5272-7.
Score: 0.014
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Herpes simplex virus 1 infected cell protein 0 forms a complex with CIN85 and Cbl and mediates the degradation of EGF receptor from cell surfaces. Proc Natl Acad Sci U S A. 2005 Apr 19; 102(16):5838-43.
Score: 0.014
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Infectious agents and cancer: criteria for a causal relation. Semin Cancer Biol. 2004 Dec; 14(6):453-71.
Score: 0.014
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Cells lacking NF-kappaB or in which NF-kappaB is not activated vary with respect to ability to sustain herpes simplex virus 1 replication and are not susceptible to apoptosis induced by a replication-incompetent mutant virus. J Virol. 2004 Nov; 78(21):11615-21.
Score: 0.014
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Herpes simplex virus protein kinase US3 activates and functionally overlaps protein kinase A to block apoptosis. Proc Natl Acad Sci U S A. 2004 Jun 22; 101(25):9411-6.
Score: 0.014
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Herpes simplex virus 1 gene products occlude the interferon signaling pathway at multiple sites. J Virol. 2004 Apr; 78(8):4185-96.
Score: 0.013
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Role of ICP0 in the strategy of conquest of the host cell by herpes simplex virus 1. J Virol. 2004 Mar; 78(5):2169-78.
Score: 0.013
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Herpes simplex virus 1 gene expression is accelerated by inhibitors of histone deacetylases in rabbit skin cells infected with a mutant carrying a cDNA copy of the infected-cell protein no. 0. J Virol. 2003 Dec; 77(23):12671-8.
Score: 0.013
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Herpes simplex virus 1 mutant in which the ICP0 HUL-1 E3 ubiquitin ligase site is disrupted stabilizes cdc34 but degrades D-type cyclins and exhibits diminished neurotoxicity. J Virol. 2003 Dec; 77(24):13194-202.
Score: 0.013
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Activation of NF-kappaB in cells productively infected with HSV-1 depends on activated protein kinase R and plays no apparent role in blocking apoptosis. Proc Natl Acad Sci U S A. 2003 Oct 14; 100(21):12408-13.
Score: 0.013
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The degradation of promyelocytic leukemia and Sp100 proteins by herpes simplex virus 1 is mediated by the ubiquitin-conjugating enzyme UbcH5a. Proc Natl Acad Sci U S A. 2003 Jul 22; 100(15):8963-8.
Score: 0.013
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The herpes simplex virus 1 US3 protein kinase blocks caspase-dependent double cleavage and activation of the proapoptotic protein BAD. J Virol. 2003 Jun; 77(11):6567-73.
Score: 0.013
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Promyelocytic leukemia protein mediates interferon-based anti-herpes simplex virus 1 effects. J Virol. 2003 Jun; 77(12):7101-5.
Score: 0.013
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The domains of glycoprotein D required to block apoptosis induced by herpes simplex virus 1 are largely distinct from those involved in cell-cell fusion and binding to nectin1. J Virol. 2003 Mar; 77(6):3759-67.
Score: 0.012
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Truncated forms of glycoprotein D of herpes simplex virus 1 capable of blocking apoptosis and of low-efficiency entry into cells form a heterodimer dependent on the presence of a cysteine located in the shared transmembrane domains. J Virol. 2002 Nov; 76(22):11469-75.
Score: 0.012
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An early regulatory function required in a cell type-dependent manner is expressed by the genomic but not the cDNA copy of the herpes simplex virus 1 gene encoding infected cell protein 0. J Virol. 2002 Oct; 76(19):9744-55.
Score: 0.012
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Herpes simplex viruses: is a vaccine tenable? J Clin Invest. 2002 Jul; 110(2):145-51.
Score: 0.012
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Characterization of the novel E3 ubiquitin ligase encoded in exon 3 of herpes simplex virus-1-infected cell protein 0. Proc Natl Acad Sci U S A. 2002 Jun 11; 99(12):7889-94.
Score: 0.012
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Of the three tegument proteins that package mRNA in herpes simplex virions, one (VP22) transports the mRNA to uninfected cells for expression prior to viral infection. Proc Natl Acad Sci U S A. 2002 Jun 11; 99(12):8318-23.
Score: 0.012
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Cation-independent mannose 6-phosphate receptor blocks apoptosis induced by herpes simplex virus 1 mutants lacking glycoprotein D and is likely the target of antiapoptotic activity of the glycoprotein. J Virol. 2002 Jun; 76(12):6197-204.
Score: 0.012
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Second-site mutation outside of the U(S)10-12 domain of Deltagamma(1)34.5 herpes simplex virus 1 recombinant blocks the shutoff of protein synthesis induced by activated protein kinase R and partially restores neurovirulence. J Virol. 2002 Feb; 76(3):942-9.
Score: 0.011
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U(S)3 protein kinase of herpes simplex virus 1 blocks caspase 3 activation induced by the products of U(S)1.5 and U(L)13 genes and modulates expression of transduced U(S)1.5 open reading frame in a cell type-specific manner. J Virol. 2002 Jan; 76(2):743-54.
Score: 0.011
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RNAs extracted from herpes simplex virus 1 virions: apparent selectivity of viral but not cellular RNAs packaged in virions. J Virol. 2001 Sep; 75(17):8105-16.
Score: 0.011
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The US3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the absence of other viral proteins. Proc Natl Acad Sci U S A. 2001 Aug 28; 98(18):10410-5.
Score: 0.011
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The domains of glycoprotein D required to block apoptosis depend on whether glycoprotein D is present in the virions carrying herpes simplex virus 1 genome lacking the gene encoding the glycoprotein. J Virol. 2001 Jul; 75(13):6166-72.
Score: 0.011
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Herpes simplex virus 1 alpha regulatory protein ICP0 functionally interacts with cellular transcription factor BMAL1. Proc Natl Acad Sci U S A. 2001 Feb 13; 98(4):1877-82.
Score: 0.011
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Posttranslational processing of infected cell protein 22 mediated by viral protein kinases is sensitive to amino acid substitutions at distant sites and can be cell-type specific. J Virol. 2000 Dec; 74(23):11210-4.
Score: 0.011
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Glycoprotein D or J delivered in trans blocks apoptosis in SK-N-SH cells induced by a herpes simplex virus 1 mutant lacking intact genes expressing both glycoproteins. J Virol. 2000 Dec; 74(24):11782-91.
Score: 0.011
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Herpes simplex virus 1 open reading frames O and P are not necessary for establishment of latent infection in mice. J Virol. 2000 Oct; 74(19):9019-27.
Score: 0.010
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The essential protein encoded by the UL31 gene of herpes simplex virus 1 depends for its stability on the presence of UL34 protein. Proc Natl Acad Sci U S A. 2000 Sep 26; 97(20):11002-7.
Score: 0.010
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hnRNPA2B1 Associated with Recruitment of RNA into Exosomes Plays a Key Role in Herpes Simplex Virus 1 Release from Infected Cells. J Virol. 2020 06 16; 94(13).
Score: 0.010
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The herpes simplex virus 1 U(L)34 protein interacts with a cytoplasmic dynein intermediate chain and targets nuclear membrane. J Virol. 2000 Feb; 74(3):1355-63.
Score: 0.010
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Identification of a novel expressed open reading frame situated between genes U(L)20 and U(L)21 of the herpes simplex virus 1 genome. Virology. 2000 Jan 20; 266(2):275-85.
Score: 0.010
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Small dense nuclear bodies are the site of localization of herpes simplex virus 1 U(L)3 and U(L)4 proteins and of ICP22 only when the latter protein is present. J Virol. 2000 Jan; 74(1):523-8.
Score: 0.010
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Replication-competent herpes simplex viral vectors for cancer therapy. Adv Virus Res. 2000; 55:409-24.
Score: 0.010
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GADD45? Activated Early in the Course of Herpes Simplex Virus 1 Infection Suppresses the Activation of a Network of Innate Immunity Genes. J Virol. 2019 04 01; 93(7).
Score: 0.009
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RIG-I-like receptor LGP2 protects tumor cells from ionizing radiation. Proc Natl Acad Sci U S A. 2014 Jan 28; 111(4):E484-91.
Score: 0.007
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Increased oncolytic efficacy for high-grade gliomas by optimal integration of ionizing radiation into the replicative cycle of HSV-1. Gene Ther. 2011 Nov; 18(11):1098-102.
Score: 0.005
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Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling. Int J Radiat Biol. 2009 May; 85(5):421-31.
Score: 0.005
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The order Herpesvirales. Arch Virol. 2009; 154(1):171-7.
Score: 0.005
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An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer. Proc Natl Acad Sci U S A. 2008 Nov 25; 105(47):18490-5.
Score: 0.005
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Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells. Cancer Res. 2007 Oct 01; 67(19):9214-20.
Score: 0.004
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Systemic delivery of (gamma1)34.5-deleted herpes simplex virus-1 selectively targets and treats distant human xenograft tumors that express high MEK activity. Cancer Res. 2007 Sep 01; 67(17):8301-6.
Score: 0.004
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ReVOLT: radiation-enhanced viral oncolytic therapy. Int J Radiat Oncol Biol Phys. 2006 Nov 01; 66(3):637-46.
Score: 0.004
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Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1. J Virol. 2006 Feb; 80(3):1110-20.
Score: 0.004
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Ionizing radiation activates late herpes simplex virus 1 promoters via the p38 pathway in tumors treated with oncolytic viruses. Cancer Res. 2005 Oct 15; 65(20):9479-84.
Score: 0.004
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Increased efficacy of an interleukin-12-secreting herpes simplex virus in a syngeneic intracranial murine glioma model. Neuro Oncol. 2005 Jul; 7(3):213-24.
Score: 0.004
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Modulation of vascular remodeling induced by a brief intraluminal exposure to the recombinant R7020 strain of Herpes simplex-1. J Vasc Surg. 2005 Jan; 41(1):115-21.
Score: 0.004
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STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells. Proc Natl Acad Sci U S A. 2004 Feb 10; 101(6):1714-9.
Score: 0.003
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Sustained inhibition of experimental neointimal hyperplasia with a genetically modified herpes simplex virus. J Vasc Surg. 2003 Jun; 37(6):1294-300.
Score: 0.003
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The use of a genetically engineered herpes simplex virus (R7020) with ionizing radiation for experimental hepatoma. Gene Ther. 2002 Jan; 9(1):75-80.
Score: 0.003
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Prevention of restenosis by a herpes simplex virus mutant capable of controlled long-term expression in vascular tissue in vivo. Gene Ther. 2001 Dec; 8(24):1840-6.
Score: 0.003
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Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts. Proc Natl Acad Sci U S A. 2001 Oct 23; 98(22):12665-70.
Score: 0.003
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Expression of interleukin-4 but not of interleukin-10 from a replicative herpes simplex virus type 1 viral vector precludes experimental allergic encephalomyelitis. Gene Ther. 2001 May; 8(10):769-77.
Score: 0.003
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Genetically engineered HSV in the treatment of glioma: a review. Rev Med Virol. 2000 Jan-Feb; 10(1):17-30.
Score: 0.002