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Bernard Roizman to Viral Proteins

This is a "connection" page, showing publications Bernard Roizman has written about Viral Proteins.
Connection Strength

12.763
  1. Tristetraprolin Recruits the Herpes Simplex Virion Host Shutoff RNase to AU-Rich Elements in Stress Response mRNAs To Enable Their Cleavage. J Virol. 2015 May; 89(10):5643-50.
    View in: PubMed
    Score: 0.456
  2. HSV-1 degrades, stabilizes, requires, or is stung by STING depending on ICP0, the US3 protein kinase, and cell derivation. Proc Natl Acad Sci U S A. 2014 Feb 04; 111(5):E611-7.
    View in: PubMed
    Score: 0.421
  3. The nuclear-cytoplasmic shuttling of virion host shutoff RNase is enabled by pUL47 and an embedded nuclear export signal and defines the sites of degradation of AU-rich and stable cellular mRNAs. J Virol. 2013 Dec; 87(24):13569-78.
    View in: PubMed
    Score: 0.413
  4. Selective degradation of mRNAs by the HSV host shutoff RNase is regulated by the UL47 tegument protein. Proc Natl Acad Sci U S A. 2013 Apr 30; 110(18):E1669-75.
    View in: PubMed
    Score: 0.399
  5. The herpes simplex virus host shutoff RNase degrades cellular and viral mRNAs made before infection but not viral mRNA made after infection. J Virol. 2013 Apr; 87(8):4516-22.
    View in: PubMed
    Score: 0.394
  6. The virion host shutoff RNase plays a key role in blocking the activation of protein kinase R in cells infected with herpes simplex virus 1. J Virol. 2013 Mar; 87(6):3271-6.
    View in: PubMed
    Score: 0.392
  7. Checkpoints in productive and latent infections with herpes simplex virus 1: conceptualization of the issues. J Neurovirol. 2011 Dec; 17(6):512-7.
    View in: PubMed
    Score: 0.361
  8. US3 protein kinase of HSV-1 cycles between the cytoplasm and nucleus and interacts with programmed cell death protein 4 (PDCD4) to block apoptosis. Proc Natl Acad Sci U S A. 2011 Aug 30; 108(35):14632-6.
    View in: PubMed
    Score: 0.356
  9. The histone acetyltransferase CLOCK is an essential component of the herpes simplex virus 1 transcriptome that includes TFIID, ICP4, ICP27, and ICP22. J Virol. 2011 Sep; 85(18):9472-7.
    View in: PubMed
    Score: 0.353
  10. Role of herpes simplex virus ICP27 in the degradation of mRNA by virion host shutoff RNase. J Virol. 2010 Oct; 84(19):10182-90.
    View in: PubMed
    Score: 0.330
  11. The virion-packaged endoribonuclease of herpes simplex virus 1 cleaves mRNA in polyribosomes. Proc Natl Acad Sci U S A. 2009 Jul 21; 106(29):12139-44.
    View in: PubMed
    Score: 0.308
  12. Role of cdk9 in the optimization of expression of the genes regulated by ICP22 of herpes simplex virus 1. J Virol. 2008 Nov; 82(21):10591-9.
    View in: PubMed
    Score: 0.290
  13. Expression of gamma interferon-dependent genes is blocked independently by virion host shutoff RNase and by US3 protein kinase. J Virol. 2008 May; 82(10):4688-96.
    View in: PubMed
    Score: 0.280
  14. The interaction of herpes simplex virus 1 regulatory protein ICP22 with the cdc25C phosphatase is enabled in vitro by viral protein kinases US3 and UL13. J Virol. 2008 May; 82(9):4533-43.
    View in: PubMed
    Score: 0.279
  15. Proteolytic cleavage of VP1-2 is required for release of herpes simplex virus 1 DNA into the nucleus. J Virol. 2008 Apr; 82(7):3311-9.
    View in: PubMed
    Score: 0.278
  16. Translocation and colocalization of ICP4 and ICP0 in cells infected with herpes simplex virus 1 mutants lacking glycoprotein E, glycoprotein I, or the virion host shutoff product of the UL41 gene. J Virol. 2008 Feb; 82(4):1701-13.
    View in: PubMed
    Score: 0.275
  17. In transduced cells, the US3 protein kinase of herpes simplex virus 1 precludes activation and induction of apoptosis by transfected procaspase 3. J Virol. 2007 Oct; 81(19):10242-8.
    View in: PubMed
    Score: 0.268
  18. Interaction of herpes simplex virus RNase with VP16 and VP22 is required for the accumulation of the protein but not for accumulation of mRNA. Proc Natl Acad Sci U S A. 2007 Jul 17; 104(29):12163-8.
    View in: PubMed
    Score: 0.268
  19. Mapping of key functions of the herpes simplex virus 1 U(S)3 protein kinase: the U(S)3 protein can form functional heteromultimeric structures derived from overlapping truncated polypeptides. J Virol. 2007 Feb; 81(4):1980-9.
    View in: PubMed
    Score: 0.257
  20. The virion host shutoff protein (UL41) of herpes simplex virus 1 is an endoribonuclease with a substrate specificity similar to that of RNase A. J Virol. 2006 Sep; 80(18):9341-5.
    View in: PubMed
    Score: 0.252
  21. Herpes simplex virus 1 precludes replenishment of the short-lived receptor of tumor necrosis factor alpha by virion host shutoff-dependent degradation of its mRNA. J Virol. 2006 Aug; 80(15):7756-9.
    View in: PubMed
    Score: 0.251
  22. ICP0 and the US3 protein kinase of herpes simplex virus 1 independently block histone deacetylation to enable gene expression. Proc Natl Acad Sci U S A. 2006 Jun 27; 103(26):9993-8.
    View in: PubMed
    Score: 0.249
  23. Protein kinase B/Akt is present in activated form throughout the entire replicative cycle of deltaU(S)3 mutant virus but only at early times after infection with wild-type herpes simplex virus 1. J Virol. 2006 Apr; 80(7):3341-8.
    View in: PubMed
    Score: 0.245
  24. U(S)3 and U(S)3.5 protein kinases of herpes simplex virus 1 differ with respect to their functions in blocking apoptosis and in virion maturation and egress. J Virol. 2006 Apr; 80(8):3752-64.
    View in: PubMed
    Score: 0.245
  25. The U(L)41 protein of herpes simplex virus 1 degrades RNA by endonucleolytic cleavage in absence of other cellular or viral proteins. Proc Natl Acad Sci U S A. 2006 Feb 21; 103(8):2827-32.
    View in: PubMed
    Score: 0.243
  26. Herpes simplex virus 1 ICP22 regulates the accumulation of a shorter mRNA and of a truncated US3 protein kinase that exhibits altered functions. J Virol. 2005 Jul; 79(13):8470-9.
    View in: PubMed
    Score: 0.233
  27. The UL41 protein of herpes simplex virus mediates selective stabilization or degradation of cellular mRNAs. Proc Natl Acad Sci U S A. 2004 Dec 28; 101(52):18165-70.
    View in: PubMed
    Score: 0.224
  28. Herpes simplex virus 1 activates cdc2 to recruit topoisomerase II alpha for post-DNA synthesis expression of late genes. Proc Natl Acad Sci U S A. 2003 Apr 15; 100(8):4825-30.
    View in: PubMed
    Score: 0.199
  29. Infected cell protein No. 22 is subject to proteolytic cleavage by caspases activated by a mutant that induces apoptosis. Virology. 2003 Jan 20; 305(2):364-70.
    View in: PubMed
    Score: 0.197
  30. The patterns of accumulation of cellular RNAs in cells infected with a wild-type and a mutant herpes simplex virus 1 lacking the virion host shutoff gene. Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26):17031-6.
    View in: PubMed
    Score: 0.195
  31. Overexpression of promyelocytic leukemia protein precludes the dispersal of ND10 structures and has no effect on accumulation of infectious herpes simplex virus 1 or its proteins. J Virol. 2002 Sep; 76(18):9355-67.
    View in: PubMed
    Score: 0.191
  32. Cell surface major histocompatibility complex class II proteins are regulated by the products of the gamma(1)34.5 and U(L)41 genes of herpes simplex virus 1. J Virol. 2002 Jul; 76(14):6974-86.
    View in: PubMed
    Score: 0.189
  33. Second-site mutation outside of the U(S)10-12 domain of Deltagamma(1)34.5 herpes simplex virus 1 recombinant blocks the shutoff of protein synthesis induced by activated protein kinase R and partially restores neurovirulence. J Virol. 2002 Feb; 76(3):942-9.
    View in: PubMed
    Score: 0.184
  34. U(S)3 protein kinase of herpes simplex virus 1 blocks caspase 3 activation induced by the products of U(S)1.5 and U(L)13 genes and modulates expression of transduced U(S)1.5 open reading frame in a cell type-specific manner. J Virol. 2002 Jan; 76(2):743-54.
    View in: PubMed
    Score: 0.183
  35. cdc2 cyclin-dependent kinase binds and phosphorylates herpes simplex virus 1 U(L)42 DNA synthesis processivity factor. J Virol. 2001 Nov; 75(21):10326-33.
    View in: PubMed
    Score: 0.181
  36. Posttranslational processing of infected cell protein 22 mediated by viral protein kinases is sensitive to amino acid substitutions at distant sites and can be cell-type specific. J Virol. 2000 Dec; 74(23):11210-4.
    View in: PubMed
    Score: 0.169
  37. Herpes simplex virus 1 open reading frames O and P are not necessary for establishment of latent infection in mice. J Virol. 2000 Oct; 74(19):9019-27.
    View in: PubMed
    Score: 0.168
  38. The essential protein encoded by the UL31 gene of herpes simplex virus 1 depends for its stability on the presence of UL34 protein. Proc Natl Acad Sci U S A. 2000 Sep 26; 97(20):11002-7.
    View in: PubMed
    Score: 0.167
  39. Redefining virology. Science. 2000 Jun 30; 288(5475):2327-8.
    View in: PubMed
    Score: 0.165
  40. The herpes simplex virus 1 U(L)34 protein interacts with a cytoplasmic dynein intermediate chain and targets nuclear membrane. J Virol. 2000 Feb; 74(3):1355-63.
    View in: PubMed
    Score: 0.160
  41. The disappearance of cyclins A and B and the increase in activity of the G(2)/M-phase cellular kinase cdc2 in herpes simplex virus 1-infected cells require expression of the alpha22/U(S)1.5 and U(L)13 viral genes. J Virol. 2000 Jan; 74(1):8-15.
    View in: PubMed
    Score: 0.159
  42. Small dense nuclear bodies are the site of localization of herpes simplex virus 1 U(L)3 and U(L)4 proteins and of ICP22 only when the latter protein is present. J Virol. 2000 Jan; 74(1):523-8.
    View in: PubMed
    Score: 0.159
  43. Herpes Simplex Virus 1 MicroRNA miR-H28 Exported to Uninfected Cells in Exosomes Restricts Cell-to-Cell Virus Spread by Inducing Gamma Interferon mRNA. J Virol. 2019 11 01; 93(21).
    View in: PubMed
    Score: 0.157
  44. Cells infected with herpes simplex virus 1 export to uninfected cells exosomes containing STING, viral mRNAs, and microRNAs. Proc Natl Acad Sci U S A. 2014 Nov 18; 111(46):E4991-6.
    View in: PubMed
    Score: 0.111
  45. The CoREST/REST repressor is both necessary and inimical for expression of herpes simplex virus genes. mBio. 2010 Dec 28; 2(1):e00313-10.
    View in: PubMed
    Score: 0.085
  46. Interwoven roles of cyclin D3 and cdk4 recruited by ICP0 and ICP4 in the expression of herpes simplex virus genes. J Virol. 2010 Oct; 84(19):9709-17.
    View in: PubMed
    Score: 0.083
  47. The novel HSV-1 US5-1 RNA is transcribed off a domain encoding US5, US4, US3, US2 and alpha22. Virol J. 2010 May 21; 7:103.
    View in: PubMed
    Score: 0.082
  48. ICP0 enables and monitors the function of D cyclins in herpes simplex virus 1 infected cells. Proc Natl Acad Sci U S A. 2009 Aug 25; 106(34):14576-80.
    View in: PubMed
    Score: 0.077
  49. Engagement of the lysine-specific demethylase/HDAC1/CoREST/REST complex by herpes simplex virus 1. J Virol. 2009 May; 83(9):4376-85.
    View in: PubMed
    Score: 0.075
  50. Nuclear retention of ICP0 in cells exposed to HDAC inhibitor or transfected with DNA before infection with herpes simplex virus 1. Proc Natl Acad Sci U S A. 2008 Dec 23; 105(51):20488-93.
    View in: PubMed
    Score: 0.074
  51. Role of cellular phosphatase cdc25C in herpes simplex virus 1 replication. J Virol. 2008 May; 82(9):4527-32.
    View in: PubMed
    Score: 0.070
  52. Temperature-sensitive mutations in the putative herpes simplex virus type 1 terminase subunits pUL15 and pUL33 preclude viral DNA cleavage/packaging and interaction with pUL28 at the nonpermissive temperature. J Virol. 2008 Jan; 82(1):487-94.
    View in: PubMed
    Score: 0.068
  53. Systemic delivery of (gamma1)34.5-deleted herpes simplex virus-1 selectively targets and treats distant human xenograft tumors that express high MEK activity. Cancer Res. 2007 Sep 01; 67(17):8301-6.
    View in: PubMed
    Score: 0.068
  54. Replication-competent herpes simplex virus 1 isolates selected from cells transfected with a bacterial artificial chromosome DNA lacking only the UL49 gene vary with respect to the defect in the UL41 gene encoding host shutoff RNase. J Virol. 2007 Oct; 81(20):10924-32.
    View in: PubMed
    Score: 0.067
  55. State and role of SRC family kinases in replication of herpes simplex virus 1. J Virol. 2006 Apr; 80(7):3349-59.
    View in: PubMed
    Score: 0.061
  56. Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1. J Virol. 2006 Feb; 80(3):1110-20.
    View in: PubMed
    Score: 0.061
  57. Cells lacking NF-kappaB or in which NF-kappaB is not activated vary with respect to ability to sustain herpes simplex virus 1 replication and are not susceptible to apoptosis induced by a replication-incompetent mutant virus. J Virol. 2004 Nov; 78(21):11615-21.
    View in: PubMed
    Score: 0.056
  58. Herpes simplex virus 1 induces cytoplasmic accumulation of TIA-1/TIAR and both synthesis and cytoplasmic accumulation of tristetraprolin, two cellular proteins that bind and destabilize AU-rich RNAs. J Virol. 2004 Aug; 78(16):8582-92.
    View in: PubMed
    Score: 0.055
  59. Herpes simplex virus protein kinase US3 activates and functionally overlaps protein kinase A to block apoptosis. Proc Natl Acad Sci U S A. 2004 Jun 22; 101(25):9411-6.
    View in: PubMed
    Score: 0.054
  60. Herpes simplex virus 1 gene products occlude the interferon signaling pathway at multiple sites. J Virol. 2004 Apr; 78(8):4185-96.
    View in: PubMed
    Score: 0.053
  61. The herpes simplex virus 1 UL41 gene-dependent destabilization of cellular RNAs is selective and may be sequence-specific. Proc Natl Acad Sci U S A. 2004 Mar 09; 101(10):3603-8.
    View in: PubMed
    Score: 0.053
  62. Oct-1 is posttranslationally modified and exhibits reduced capacity to bind cognate sites at late times after infection with herpes simplex virus 1. J Virol. 2003 Nov; 77(22):11927-32.
    View in: PubMed
    Score: 0.052
  63. The herpes simplex virus 1 US3 protein kinase blocks caspase-dependent double cleavage and activation of the proapoptotic protein BAD. J Virol. 2003 Jun; 77(11):6567-73.
    View in: PubMed
    Score: 0.050
  64. Promyelocytic leukemia protein mediates interferon-based anti-herpes simplex virus 1 effects. J Virol. 2003 Jun; 77(12):7101-5.
    View in: PubMed
    Score: 0.050
  65. RNAs extracted from herpes simplex virus 1 virions: apparent selectivity of viral but not cellular RNAs packaged in virions. J Virol. 2001 Sep; 75(17):8105-16.
    View in: PubMed
    Score: 0.045
  66. The US3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the absence of other viral proteins. Proc Natl Acad Sci U S A. 2001 Aug 28; 98(18):10410-5.
    View in: PubMed
    Score: 0.045
  67. The U(S)3 protein kinase blocks apoptosis induced by the d120 mutant of herpes simplex virus 1 at a premitochondrial stage. J Virol. 2001 Jun; 75(12):5491-7.
    View in: PubMed
    Score: 0.044
  68. hnRNPA2B1 Associated with Recruitment of RNA into Exosomes Plays a Key Role in Herpes Simplex Virus 1 Release from Infected Cells. J Virol. 2020 06 16; 94(13).
    View in: PubMed
    Score: 0.041
  69. Identification of a novel expressed open reading frame situated between genes U(L)20 and U(L)21 of the herpes simplex virus 1 genome. Virology. 2000 Jan 20; 266(2):275-85.
    View in: PubMed
    Score: 0.040
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Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.