Alain Labro to Ion Channel Gating
This is a "connection" page, showing publications Alain Labro has written about Ion Channel Gating.
Connection Strength
3.119
-
Inverted allosteric coupling between activation and inactivation gates in K+ channels. Proc Natl Acad Sci U S A. 2018 05 22; 115(21):5426-5431.
Score: 0.461
-
Mutations in the S6 gate isolate a late step in the activation pathway and reduce 4-AP sensitivity in shaker K(v) channel. Biophys J. 2014 Jan 07; 106(1):134-44.
Score: 0.341
-
Molecular mechanism for depolarization-induced modulation of Kv channel closure. J Gen Physiol. 2012 Nov; 140(5):481-93.
Score: 0.314
-
Properties of deactivation gating currents in Shaker channels. Biophys J. 2011 Mar 02; 100(5):L28-30.
Score: 0.280
-
The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure. J Biol Chem. 2011 Jan 07; 286(1):717-25.
Score: 0.274
-
Kv channel gating requires a compatible S4-S5 linker and bottom part of S6, constrained by non-interacting residues. J Gen Physiol. 2008 Dec; 132(6):667-80.
Score: 0.240
-
A Kv channel with an altered activation gate sequence displays both "fast" and "slow" activation kinetics. Am J Physiol Cell Physiol. 2008 Jun; 294(6):C1476-84.
Score: 0.229
-
Coupling of voltage sensing to channel opening reflects intrasubunit interactions in kv channels. J Gen Physiol. 2005 Jan; 125(1):71-80.
Score: 0.183
-
The Selectivity Filter Is Involved in the U-Type Inactivation Process of Kv2.1 and Kv3.1 Channels. Biophys J. 2020 05 19; 118(10):2612-2620.
Score: 0.132
-
Alkanols inhibit voltage-gated K(+) channels via a distinct gating modifying mechanism that prevents gate opening. Sci Rep. 2015 Nov 30; 5:17402.
Score: 0.097
-
The ladder-shaped polyether toxin gambierol anchors the gating machinery of Kv3.1 channels in the resting state. J Gen Physiol. 2013 Mar; 141(3):359-69.
Score: 0.080
-
Dual effect of phosphatidylinositol (4,5)-bisphosphate PIP(2) on Shaker K(+) [corrected] channels. J Biol Chem. 2012 Oct 19; 287(43):36158-67.
Score: 0.078
-
The electrically silent Kv6.4 subunit confers hyperpolarized gating charge movement in Kv2.1/Kv6.4 heterotetrameric channels. PLoS One. 2012; 7(5):e37143.
Score: 0.076
-
Phosphatidylinositol-4,5-bisphosphate (PIP(2)) stabilizes the open pore conformation of the Kv11.1 (hERG) channel. Biophys J. 2010 Aug 09; 99(4):1110-8.
Score: 0.067
-
The rate-dependent biophysical properties of the LQT1 H258R mutant are counteracted by a dominant negative effect on channel trafficking. J Mol Cell Cardiol. 2010 Jun; 48(6):1096-104.
Score: 0.064
-
Role of the S6 C-terminus in KCNQ1 channel gating. J Physiol. 2007 Dec 01; 585(Pt 2):325-37.
Score: 0.055
-
Modulation of HERG gating by a charge cluster in the N-terminal proximal domain. Biophys J. 2006 Dec 15; 91(12):4381-91.
Score: 0.051
-
Impaired cytoplasmic domain interactions cause co-assembly defect and loss of function in the p.Glu293Lys KNCJ2 variant isolated from an Andersen-Tawil syndrome patient. Cardiovasc Res. 2021 07 07; 117(8):1923-1934.
Score: 0.036
-
Gambierol and n-alkanols inhibit Shaker Kv channel via distinct binding sites outside the K(+) pore. Toxicon. 2016 Sep 15; 120:57-60.
Score: 0.025
-
Functional interactions between residues in the S1, S4, and S5 domains of Kv2.1. Eur Biophys J. 2011 Jun; 40(6):783-93.
Score: 0.018
-
KCNQ1 channels voltage dependence through a voltage-dependent binding of the S4-S5 linker to the pore domain. J Biol Chem. 2011 Jan 07; 286(1):707-16.
Score: 0.017