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Connection

Michael Becker to Purine Nucleotides

This is a "connection" page, showing publications Michael Becker has written about Purine Nucleotides.
Connection Strength

0.737
  1. Point mutations in PRPS1, the gene encoding the PRPP synthetase (PRS) 1 isoform, underlie X-linked PRS superactivity associated with purine nucleotide inhibitor-resistance. Adv Exp Med Biol. 1994; 370:707-10.
    View in: PubMed
    Score: 0.116
  2. Regulation of purine nucleotide synthesis in human B lymphoblasts with both hypoxanthine-guanine phosphoribosyltransferase deficiency and phosphoribosylpyrophosphate synthetase superactivity. J Biol Chem. 1992 Mar 05; 267(7):4317-21.
    View in: PubMed
    Score: 0.102
  3. PRPP and purine nucleotide metabolism in human lymphoblasts with both PRPP synthetase superactivity and HGPRT deficiency. Adv Exp Med Biol. 1989; 253B:13-20.
    View in: PubMed
    Score: 0.082
  4. Neurodevelopmental impairment and deranged PRPP and purine nucleotide synthesis in inherited superactivity of PRPP synthetase. Adv Exp Med Biol. 1989; 253A:15-22.
    View in: PubMed
    Score: 0.082
  5. Regulation of purine synthesis de novo in human fibroblasts by purine nucleotides and phosphoribosylpyrophosphate. J Biol Chem. 1987 Oct 25; 262(30):14531-7.
    View in: PubMed
    Score: 0.076
  6. Mechanisms of accelerated purine nucleotide synthesis in human fibroblasts with superactive phosphoribosylpyrophosphate synthetases. J Biol Chem. 1987 Apr 25; 262(12):5596-602.
    View in: PubMed
    Score: 0.073
  7. Accelerated transcription of PRPS1 in X-linked overactivity of normal human phosphoribosylpyrophosphate synthetase. J Biol Chem. 1999 Mar 12; 274(11):7482-8.
    View in: PubMed
    Score: 0.042
  8. Human X-linked phosphoribosylpyrophosphate synthetase superactivity is associated with distinct point mutations in the PRPS1 gene. J Biol Chem. 1993 Dec 15; 268(35):26476-81.
    View in: PubMed
    Score: 0.029
  9. Increased purine nucleotide degradation in the central nervous system (CNS) in PRPP synthetase superactivity. Adv Exp Med Biol. 1989; 253A:9-13.
    View in: PubMed
    Score: 0.021
  10. Inherited superactivity of phosphoribosylpyrophosphate synthetase: association of uric acid overproduction and sensorineural deafness. Am J Med. 1988 Sep; 85(3):383-90.
    View in: PubMed
    Score: 0.020
  11. Phosphoribosylpyrophosphate synthetase superactivity. A study of five patients with catalytic defects in the enzyme. Arthritis Rheum. 1986 Jul; 29(7):880-8.
    View in: PubMed
    Score: 0.017
  12. Superactivity of human phosphoribosyl pyrophosphate synthetase due to altered regulation by nucleotide inhibitors and inorganic phosphate. Biochim Biophys Acta. 1986 Jun 19; 882(2):168-76.
    View in: PubMed
    Score: 0.017
  13. Inherited phosphoribosylpyrophosphate synthetase superactivity due to aberrant inhibitor and activator responsiveness. Adv Exp Med Biol. 1986; 195 Pt A:59-66.
    View in: PubMed
    Score: 0.017
  14. Superactive phosphoribosylpyrophosphate synthetase with altered regulatory and catalytic properties. Adv Exp Med Biol. 1980; 122A:387-92.
    View in: PubMed
    Score: 0.011
  15. Variant human phosphoribosylpyrophosphate synthetase altered in regulatory and catalytic functions. J Clin Invest. 1980 Jan; 65(1):109-20.
    View in: PubMed
    Score: 0.011
  16. Effects of inosine on purine synthesis in normal and HGPRT-deficient human fibroblasts. Adv Exp Med Biol. 1977; 76A:370-5.
    View in: PubMed
    Score: 0.009
  17. Recent advances in the identification of enzyme abnormalities underlying excessive purine synthesis in man. Arthritis Rheum. 1975 Nov-Dec; 18(6 Suppl):687-94.
    View in: PubMed
    Score: 0.008
  18. Purine metabolism in normal and thioguanine-resistant neuroblastoma. Proc Natl Acad Sci U S A. 1973 Dec; 70(12):3880-3.
    View in: PubMed
    Score: 0.002
  19. Purine nucleotide synthesis in lymphoblasts cultured from normal subjects and a patient with Lesch-Nyhan syndrome. Biochem Genet. 1973 Jul; 9(3):261-74.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.