The University of Chicago Header Logo

Michael A. Becker

TitleEmeritus/Emerita, Professor
InstitutionUniversity of Chicago
DepartmentMedicine
AddressChicago IL 60637
vCardDownload vCard

    Collapse Research 
    Collapse research activities and funding
    R01DK028554     (BECKER, MICHAEL A)Sep 1, 1980 - Nov 30, 2002
    NIH
    REGULATION OF PURINE NUCLEOTIDE SYNTHESIS IN HUMANS
    Role: Principal Investigator
    R01AM028554     (BECKER, MICHAEL A)Sep 1, 1980 - Apr 30, 1986
    NIH
    REGULATION OF PURINE NUCLEOTIDE SYNTHESIS IN MAN
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Becker A, Nguyen H, Becker M, Wood A, Lawrenson R. Changing patterns of otitis media in the Waikato region during the COVID-19 pandemic. J Prim Health Care. 2023 09; 15(3):224-229. PMID: 37756244.
      Citations:    Fields:    Translation:HumansPHPublic Health
    2. Saag KG, Becker MA, White WB, Whelton A, Borer JS, Gorelick PB, Hunt B, Castillo M, Gunawardhana L, CARES Investigators. Evaluation of the Relationship Between Serum Urate Levels, Clinical Manifestations of Gout, and Death From Cardiovascular Causes in Patients Receiving Febuxostat or Allopurinol in an Outcomes Trial. Arthritis Rheumatol. 2022 09; 74(9):1593-1601. PMID: 35536764; PMCID: PMC9541704.
      Citations: 5     Fields:    Translation:Humans
    3. Liu HW, Becker MA, Matsuzaki K, Kumar R, Sandoghdar V, Götzinger S. Robust Tipless Positioning Device for Near-Field Investigations: Press and Roll Scan (PROscan). ACS Nano. 2022 Aug 23; 16(8):12831-12839. PMID: 35920717; PMCID: PMC9413428.
      Citations:    Fields:    
    4. Ellis DM, Hickey S, Prieto P, McLaughlin C, Felgoise SH, Becker M, O'Connor M, Puleo M, Reddy T, Markey D, Kim L, Bernhardt PW. Parkinson's Disease Medication Administration During a Care Transition: The Impact of Interprofessional Team Simulation on Student Competency, Comfort, and Knowledge. Nurs Educ Perspect. 2022 May-Jun 01; 43(3):164-170. PMID: 34974503.
      Citations:    Fields:    Translation:Humans
    5. Norris DJ, Becker MA, Bernasconi C, Bodnarchuk MI, Rainò G, Kovalenko MV, Mahrt RF, Stöferle T. Unraveling the Origin of the Long Fluorescence Decay Component of Cesium Lead Halide Perovskite Nanocrystals. ACS Nano. 2020 Nov 24; 14(11):14939-14946. PMID: 33174717; PMCID: PMC7690045.
      Citations: 2     Fields:    
    6. Antolinez FV, Rabouw FT, Rossinelli AA, Keitel RC, Cocina A, Becker MA, Norris DJ. Trion Emission Dominates the Low-Temperature Photoluminescence of CdSe Nanoplatelets. Nano Lett. 2020 Aug 12; 20(8):5814-5820. PMID: 32589429.
      Citations: 3     Fields:    
    7. Hassoun H, Bayer R, Devlin S, Gentile T, Becker M, O'Dweyer K, Lesser M, Landau H, Chung D, Giralt S. A phase II clinical trial of lenalidomide intensification in patients with serologic/asymptomatic progression of multiple myeloma while on lenalidomide maintenance: a tri-state transplant consortium study. Leuk Lymphoma. 2020 02; 61(2):488-490. PMID: 31957517; PMCID: PMC7580780.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    8. Jahn L, Kramann R, Marx N, Becker M, Schlieper G, Floege J. Speckle Tracking Echocardiography and All-Cause and Cardiovascular Mortality Risk in Chronic Kidney Disease Patients. Kidney Blood Press Res. 2019; 44(4):690-703. PMID: 31416075.
      Citations: 4     Fields:    Translation:Humans
    9. Courtright KR, Chivers C, Becker M, Regli SH, Pepper LC, Draugelis ME, O'Connor NR. Electronic Health Record Mortality Prediction Model for Targeted Palliative Care Among Hospitalized Medical Patients: a Pilot Quasi-experimental Study. J Gen Intern Med. 2019 09; 34(9):1841-1847. PMID: 31313110; PMCID: PMC6712114.
      Citations: 25     Fields:    Translation:Humans
    10. Becker MA, Bodnarchuk MI, Mahrt RF, Kovalenko MV, Rainò G, Stöferle T. Polymer and Colloid Highlights. Chimia (Aarau). 2019 Feb 27; 73(1-2):92. PMID: 30814009.
      Citations:    Fields:    
    11. Saag KG, Becker MA, Whelton A, Hunt B, Castillo M, Kisfalvi K, Gunawardhana L. Efficacy and Safety of Febuxostat Extended and Immediate Release in Patients With Gout and Renal Impairment: A Phase III Placebo-Controlled Study. Arthritis Rheumatol. 2019 01; 71(1):143-153. PMID: 30073793; PMCID: PMC6590450.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    12. Scarpelli L, Masia F, Borri P, Langbein W, Becker MA, Nedelcu G, Rainò G, Stöferle T, Kovalenko MV, Mahrt RF. Long Exciton Dephasing Time and Coherent Phonon Coupling in CsPbBr2Cl Perovskite Nanocrystals. Nano Lett. 2018 12 12; 18(12):7546-7551. PMID: 30407011.
      Citations: 18     Fields:    
    13. Kovalenko MV, Rainò G, Becker MA, Bodnarchuk MI, Mahrt RF, Stöferle T. Superfluorescence from lead halide perovskite quantum dot superlattices. Nature. 2018 11; 563(7733):671-675. PMID: 30405237.
      Citations: 81     Fields:    
    14. Gunawardhana L, Becker MA, Whelton A, Hunt B, Castillo M, Saag K. Efficacy and safety of febuxostat extended release and immediate release in patients with gout and moderate renal impairment: phase II placebo-controlled study. Arthritis Res Ther. 2018 05 30; 20(1):99. PMID: 29848361; PMCID: PMC5977466.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    15. White WB, Saag KG, Becker MA, Borer JS, Gorelick PB, Whelton A, Hunt B, Castillo M, Gunawardhana L, CARES Investigators. Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout. N Engl J Med. 2018 Mar 29; 378(13):1200-1210. PMID: 29527974.
      Citations: 227     Fields:    Translation:Humans
    16. Hamada S, Keszei A, Napp A, Almalla M, Becker M, Altiok E, Scharrenbroich J, Schröder J. Use of two-dimensional speckle tracking echocardiography to predict cardiac events: Comparison of patients with acute myocardial infarction and chronic coronary artery disease. Clin Cardiol. 2018 Jan; 41(1):111-118. PMID: 29359809; PMCID: PMC6489831.
      Citations: 11     Fields:    Translation:Humans
    17. Vaxenburg R, Nedelcu G, Sercel PC, Shabaev A, Mehl MJ, Michopoulos JG, Lambrakos SG, Bernstein N, Lyons JL, Kovalenko MV, Norris DJ, Efros AL, Becker MA, Stöferle T, Mahrt RF, Rainò G. Bright triplet excitons in caesium lead halide perovskites. Nature. 2018 01 10; 553(7687):189-193. PMID: 29323292.
      Citations: 101     Fields:    
    18. Herrick AL, Peytrignet S, Lunt M, Pan X, Hesselstrand R, Silman AJ, Dinsdale G, Brown E, Distler O, Fligelstone K, Gregory WJ, Ochiel R, Vonk MC, Ancuta C, Ong VH, Hudson M, Matucci-Cerinic M, Balbir-Gurman A, Jobanputra P, Jordan AC, Stevens W, Moinzadeh P, Hall FC, Anderson ME, Madhok R, Akil M, Buch MH, Chung L, Damjanov NS, Gunawardena H, Lanyon P, Ahmad Y, Chakravarty K, MacGregor AJ, McHugh N, Roddy J, Carreira PE, Fauchais AL, Hamilton J, McLaren JS, van Laar JM, Pathare S, Proudman SM, Rudin A, Sahhar J, Serratrice C, Sheeran T, Veale DJ, Grange C, Denton CP, Mouthon L, Czirják L, Distler JHW, Farge D, Midtvedt Ø, Agard C, Diot E, Jacobsen S, Müller-Ladner U, Riemekasten G, Becker M, Hachulla E, Inanç M, Coppere B, Trad GS. Patterns and predictors of skin score change in early diffuse systemic sclerosis from the European Scleroderma Observational Study. Ann Rheum Dis. 2018 04; 77(4):563-570. PMID: 29306872; PMCID: PMC5890636.
      Citations: 28     Fields:    Translation:Humans
    19. Herrick AL, Pan X, Lunt M, Hesselstrand R, Silman A, Brown E, Distler O, Fligelstone K, Gregory WJ, Ochiel R, Vonk M, Ancuta C, Ong VH, Hudson M, Matucci-Cerinic M, Balbir-Gurman A, Jordan AC, Jobanputra P, Stevens W, Hall FC, Anderson ME, Madhok R, Akil M, Buch MH, Chung L, Damjanov N, Gunawardena H, Lanyon P, Ahmad Y, Chakravarty K, MacGregor AJ, McHugh N, Roddy J, Carreira PE, Fauchais AL, Hamilton J, McLaren JS, van Laar JM, Pathare S, Proudman S, Rudin A, Sahhar J, Serratrice C, Sheeran T, Veale DJ, Grange C, Denton CP, Peytrignet S, Mouthon L, Czirják L, Distler JHW, Farge D, Midtvedt Ø, Moinzadeh P, Agard C, Diot E, Jacobsen S, Müller-Ladner U, Riemekasten G, Becker M, Hachulla E, Inanç M, Coppere B, Trad GS. Treatment outcome in early diffuse cutaneous systemic sclerosis: the European Scleroderma Observational Study (ESOS). Ann Rheum Dis. 2017 Jul; 76(7):1207-1218. PMID: 28188239; PMCID: PMC5530354.
      Citations: 47     Fields:    Translation:Humans
    20. Saag KG, Fitz-Patrick D, Kopicko J, Fung M, Bhakta N, Adler S, Storgard C, Baumgartner S, Becker MA. Lesinurad Combined With Allopurinol: A Randomized, Double-Blind, Placebo-Controlled Study in Gout Patients With an Inadequate Response to Standard-of-Care Allopurinol (a US-Based Study). Arthritis Rheumatol. 2017 01; 69(1):203-212. PMID: 27564409.
      Citations: 58     Fields:    Translation:Humans
    21. Becker MA. Summary of the 2015 Purine and Pyrimidine Society/Purine Metabolic Patients Association H. Anne Simmonds Memorial Lecture. Nucleosides Nucleotides Nucleic Acids. 2016 Dec; 35(10-12):502-506. PMID: 27906633.
      Citations: 2     Fields:    Translation:HumansCells
    22. Saag KG, Whelton A, Becker MA, MacDonald P, Hunt B, Gunawardhana L. Impact of Febuxostat on Renal Function in Gout Patients With Moderate-to-Severe Renal Impairment. Arthritis Rheumatol. 2016 08; 68(8):2035-43. PMID: 26894653.
      Citations: 40     Fields:    Translation:Humans
    23. Dhakal S, Bates JE, Casulo C, Friedberg JW, Becker MW, Liesveld JL, Constine LS. Patterns and Timing of Failure for Diffuse Large B-Cell Lymphoma After Initial Therapy in a Cohort Who Underwent Autologous Bone Marrow Transplantation for Relapse. Int J Radiat Oncol Biol Phys. 2016 10 01; 96(2):372-378. PMID: 27473813.
      Citations: 7     Fields:    Translation:Humans
    24. Keszei A, Schroeder J, Hamada S, Gründlinger N, Rubeau T, Altiok E, Ulbrich K, Marx N, Becker M. Myocardial deformation by strain echocardiography identifies patients with acute coronary syndrome and non-diagnostic ECG presenting in a chest pain unit: a prospective study of diagnostic accuracy. Clin Res Cardiol. 2016 Mar; 105(3):248-56. PMID: 26349786.
      Citations: 14     Fields:    Translation:Humans
    25. Becker MA, Fitz-Patrick D, Choi HK, Dalbeth N, Storgard C, Cravets M, Baumgartner S. An open-label, 6-month study of allopurinol safety in gout: The LASSO study. Semin Arthritis Rheum. 2015 Oct; 45(2):174-83. PMID: 26190562.
      Citations: 32     Fields:    Translation:HumansCTClinical Trials
    26. Chang J, McGrory BJ, Rana A, Becker MW, Babikian GM, Guay P, Smith KA. Current Orthopaedic Surgeon Practices for Nonarthroplasty Treatment of Osteoarthritis of Adult Hip and Knee. J Surg Orthop Adv. 2015; 24(4):213-20. PMID: 26731383.
      Citations: 5     Fields:    Translation:Humans
    27. Becker MA, Perez-Ruiz F. Inflammation: a possible mechanism for a causative role of hyperuricemia/gout in cardiovascular disease. Curr Med Res Opin. 2015; 31 Suppl 2:9-14. PMID: 26414731.
      Citations: 24     Fields:    Translation:HumansAnimals
    28. Yood RA, Ottery FD, Sundy JS, Becker MA, Baraf HS. Infusion-related reactions with pegloticase, a recombinant uricase for the treatment of chronic gout refractory to conventional therapy. J Clin Rheumatol. 2014 Dec; 20(8):427-32. PMID: 25417679; PMCID: PMC4280274.
      Citations: 23     Fields:    Translation:Humans
    29. Becker M, Hundemer A, Zwicker C, Altiok E, Krohn T, Mottaghy FM, Lente C, Kelm M, Marx N, Hoffmann R. Detection of coronary artery disease in postmenopausal women: the significance of integrated stress imaging tests in a 4-year prognostic study. Clin Res Cardiol. 2015 Mar; 104(3):258-71. PMID: 25367244.
      Citations: 7     Fields:    Translation:Humans
    30. Becker MA, Simkin PA, Sorensen LB. Urate transporters: transforming the face of hyperuricemia and gout. J Rheumatol. 2014 Oct; 41(10):1910-2. PMID: 25179848.
      Citations: 1     Fields:    Translation:Humans
    31. Guzman ML, Yang N, Sharma KK, Balys M, Corbett CA, Jordan CT, Becker MW, Steidl U, Abdel-Wahab O, Levine RL, Marcucci G, Roboz GJ, Hassane DC. Selective activity of the histone deacetylase inhibitor AR-42 against leukemia stem cells: a novel potential strategy in acute myelogenous leukemia. Mol Cancer Ther. 2014 Aug; 13(8):1979-90. PMID: 24934933; PMCID: PMC4383047.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    32. Lipsky PE, Calabrese LH, Kavanaugh A, Sundy JS, Wright D, Wolfson M, Becker MA. Pegloticase immunogenicity: the relationship between efficacy and antibody development in patients treated for refractory chronic gout. Arthritis Res Ther. 2014 Mar 04; 16(2):R60. PMID: 24588936; PMCID: PMC4060440.
      Citations: 83     Fields:    Translation:Humans
    33. Advani AS, McDonough S, Coutre S, Wood B, Radich J, Mims M, O'Donnell M, Elkins S, Becker M, Othus M, Appelbaum FR. SWOG S0910: a phase 2 trial of clofarabine/cytarabine/epratuzumab for relapsed/refractory acute lymphocytic leukaemia. Br J Haematol. 2014 May; 165(4):504-9. PMID: 24579885; PMCID: PMC4209396.
      Citations: 35     Fields:    Translation:HumansCTClinical Trials
    34. Chaichian Y, Chohan S, Becker MA. Long-term management of gout: nonpharmacologic and pharmacologic therapies. Rheum Dis Clin North Am. 2014 May; 40(2):357-74. PMID: 24703352.
      Citations: 6     Fields:    Translation:Humans
    35. Dhakshinamoorthy S, Alexandrov T, Becker M, Bretschneider T, Buerkert A, Crecelius AC, De Waele D, Elsen A, Heckel DG, Heklau H, Hertweck C, Kai M, Knop K, Krafft C, Maddula RK, Schneider B, Schubert US, Sikora RA, Swennen RL, Hölscher D, Matthäus C, Popp J, Svatoš A. Phenalenone-type phytoalexins mediate resistance of banana plants (Musa spp.) to the burrowing nematode Radopholus similis. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):105-10. PMID: 24324151; PMCID: PMC3890884.
      Citations: 35     Fields:    Translation:Animals
    36. Wertheimer A, Morlock R, Becker MA. A revised estimate of the burden of illness of gout. Curr Ther Res Clin Exp. 2013 Dec; 75:1-4. PMID: 24465034; PMCID: PMC3898191.
      Citations: 46     Fields:    
    37. Liesveld JL, Phillips GL, Becker M, Constine LS, Friedberg J, Andolina JR, Milner LA, DeBolt J, Smudzin T, Hyrien O, Erickson-Miller CL, Johnson BM, Dawson KL, Chen Y. A phase 1 trial of eltrombopag in patients undergoing stem cell transplantation after total body irradiation. Biol Blood Marrow Transplant. 2013 Dec; 19(12):1745-52. PMID: 24120380.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    38. Baraf HS, Becker MA, Gutierrez-Urena SR, Treadwell EL, Vazquez-Mellado J, Rehrig CD, Ottery FD, Sundy JS, Yood RA. Tophus burden reduction with pegloticase: results from phase 3 randomized trials and open-label extension in patients with chronic gout refractory to conventional therapy. Arthritis Res Ther. 2013 Sep 26; 15(5):R137. PMID: 24286509; PMCID: PMC3979037.
      Citations: 31     Fields:    Translation:HumansCTClinical Trials
    39. Liesveld JL, O'Dwyer K, Walker A, Becker MW, Ifthikharuddin JJ, Mulford D, Chen R, Bechelli J, Rosell K, Minhajuddin M, Jordan CT, Phillips GL. A phase I study of decitabine and rapamycin in relapsed/refractory AML. Leuk Res. 2013 Dec; 37(12):1622-7. PMID: 24138944.
      Citations: 14     Fields:    Translation:HumansCTClinical Trials
    40. Hashmi S, Oliva JL, Liesveld JL, Phillips GL, Milner L, Becker MW. The hematopoietic cell transplantation specific comorbidity index and survival after extracorporeal photopheresis, pentostatin, and reduced dose total body irradiation conditioning prior to allogeneic stem cell transplantation. Leuk Res. 2013 Sep; 37(9):1052-6. PMID: 23830733.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    41. Becker MA, MacDonald PA, Hunt BJ, Jackson RL. Diabetes and gout: efficacy and safety of febuxostat and allopurinol. Diabetes Obes Metab. 2013 Nov; 15(11):1049-55. PMID: 23683134; PMCID: PMC3902994.
      Citations: 14     Fields:    Translation:Humans
    42. Becker MA, Baraf HS, Yood RA, Dillon A, Ottery FD, Khanna D, Sundy JS, Vázquez-Mellado J. Long-term safety of pegloticase in chronic gout refractory to conventional treatment. Ann Rheum Dis. 2013 Sep 01; 72(9):1469-74. PMID: 23144450; PMCID: PMC3756467.
      Citations: 37     Fields:    Translation:Humans
    43. Komori M, Matsuyama Y, Nirasawa T, Thiele H, Becker M, Alexandrov T, Saida T, Tanaka M, Matsuo H, Tomimoto H, Takahashi R, Tashiro K, Ikegawa M, Kondo T. Proteomic pattern analysis discriminates among multiple sclerosis-related disorders. Ann Neurol. 2012 May; 71(5):614-23. PMID: 22522477.
      Citations: 10     Fields:    Translation:Humans
    44. Becker MA. Ser médico ...as a physician and professor at the University of Chicago. Rev Clin Esp. 2012 Mar; 212(3):151-4. PMID: 22532983.
      Citations:    Fields:    Translation:Humans
    45. Chohan S, Becker MA, MacDonald PA, Chefo S, Jackson RL. Women with gout: efficacy and safety of urate-lowering with febuxostat and allopurinol. Arthritis Care Res (Hoboken). 2012 Feb; 64(2):256-61. PMID: 22052584.
      Citations: 11     Fields:    Translation:HumansCTClinical Trials
    46. Becker MA, MacDonald PA, Hunt B, Gunawardhana L. Treating hyperuricemia of gout: safety and efficacy of febuxostat and allopurinol in older versus younger subjects. Nucleosides Nucleotides Nucleic Acids. 2011 Dec; 30(12):1011-7. PMID: 22132950.
      Citations: 5     Fields:    Translation:Humans
    47. Bruand J, Alexandrov T, Sistla S, Wisztorski M, Becker M, Salzet M, Fournier I, Macagno E, Bafna V, Meriaux C. AMASS: algorithm for MSI analysis by semi-supervised segmentation. J Proteome Res. 2011 Oct 07; 10(10):4734-43. PMID: 21800894; PMCID: PMC3190602.
      Citations: 12     Fields:    Translation:Animals
    48. Sundy JS, Baraf HS, Yood RA, Edwards NL, Gutierrez-Urena SR, Treadwell EL, White WB, Lipsky PE, Horowitz Z, Huang W, Maroli AN, Waltrip RW, Hamburger SA, Becker MA, Vázquez-Mellado J. Efficacy and tolerability of pegloticase for the treatment of chronic gout in patients refractory to conventional treatment: two randomized controlled trials. JAMA. 2011 Aug 17; 306(7):711-20. PMID: 21846852.
      Citations: 172     Fields:    Translation:Humans
    49. Dalbeth N, McQueen FM, Singh JA, MacDonald PA, Edwards NL, Schumacher HR, Simon LS, Stamp LK, Neogi T, Gaffo AL, Khanna PP, Becker MA, Taylor WJ. Tophus measurement as an outcome measure for clinical trials of chronic gout: progress and research priorities. J Rheumatol. 2011 Jul; 38(7):1458-61. PMID: 21724716; PMCID: PMC3882031.
      Citations: 7     Fields:    Translation:Humans
    50. Stamp LK, Khanna PP, Dalbeth N, Boers M, Maksymowych WP, Schumacher HR, Becker MA, MacDonald PA, Edwards NL, Singh JA, Simon LS, McQueen FM, Neogi T, Gaffo AL, Strand V, Taylor WJ. Serum urate in chronic gout--will it be the first validated soluble biomarker in rheumatology? J Rheumatol. 2011 Jul; 38(7):1462-6. PMID: 21724717; PMCID: PMC3645864.
      Citations: 8     Fields:    Translation:Humans
    51. Taylor WJ, Singh JA, Saag KG, Dalbeth N, MacDonald PA, Edwards NL, Simon LS, Stamp LK, Neogi T, Gaffo AL, Khanna PP, Becker MA, Schumacher HR. Bringing it all together: a novel approach to the development of response criteria for chronic gout clinical trials. J Rheumatol. 2011 Jul; 38(7):1467-70. PMID: 21724718.
      Citations: 7     Fields:    Translation:Humans
    52. Singh JA, Taylor WJ, Simon LS, Khanna PP, Stamp LK, McQueen FM, Neogi T, Gaffo AL, Becker MA, MacDonald PA, Dabbous O, Strand V, Dalbeth ND, Aletaha D, Edwards NL, Schumacher HR. Patient-reported outcomes in chronic gout: a report from OMERACT 10. J Rheumatol. 2011 Jul; 38(7):1452-7. PMID: 21724715; PMCID: PMC3850171.
      Citations: 42     Fields:    Translation:Humans
    53. Milner LA, Becker MW, Bernstein SH, Bruckner L, Friedberg JW, Holland GA, Ifthikharuddin JJ, Liesveld JL, Mathes EJ, Menchel HL, Mullen CA, Sasson T, Phillips GL. Intra-arterial methylprednisolone for the management of steroid-refractory acute gastrointestinal and hepatic graft versus host disease. Am J Hematol. 2011 Aug; 86(8):712-4. PMID: 21630317.
      Citations:    Fields:    Translation:Humans
    54. Claure N, Bancalari E, D'Ugard C, Nelin L, Stein M, Ramanathan R, Hernandez R, Donn SM, Becker M, Bachman T. Multicenter crossover study of automated control of inspired oxygen in ventilated preterm infants. Pediatrics. 2011 Jan; 127(1):e76-83. PMID: 21187305.
      Citations: 31     Fields:    Translation:Humans
    55. Edwards NL, Sundy JS, Forsythe A, Blume S, Pan F, Becker MA. Work productivity loss due to flares in patients with chronic gout refractory to conventional therapy. J Med Econ. 2011; 14(1):10-5. PMID: 21138339.
      Citations: 29     Fields:    Translation:Humans
    56. Phillips GL, Bernstein SH, Liesveld JL, Abboud CN, Becker MW, Constine LS, Ifthikharuddin JJ, Loughner JE, Milner LA, Vesole DH, Friedberg JW. A Phase I trial: dose escalation of melphalan in the "BEAM" regimen using amifostine cytoprotection. Biol Blood Marrow Transplant. 2011 Jul; 17(7):1033-42. PMID: 21074630.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    57. Becker MA, Ruoff GE. What do I need to know about gout? J Fam Pract. 2010 Jun; 59(6 Suppl):S1-8. PMID: 20544070.
      Citations: 6     Fields:    Translation:Humans
    58. Becker MA, Schumacher HR, Espinoza LR, Wells AF, MacDonald P, Lloyd E, Lademacher C. The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial. Arthritis Res Ther. 2010; 12(2):R63. PMID: 20370912; PMCID: PMC2888216.
      Citations: 156     Fields:    Translation:Humans
    59. Knackstedt C, Mischke K, Schummers G, Becker M, Franke A, Schmid M, Spuentrup E, Mahnken A, Lang RM, Kelm M, Schauerte P, Mühlenbruch G, Kühl H, Günther RW. Registration of coronary venous anatomy to the site of the latest mechanical contraction. Acta Cardiol. 2010 Apr; 65(2):161-70. PMID: 20458823.
      Citations: 2     Fields:    Translation:Humans
    60. Kozhevnikov M, Blazhenkova O, Becker M. Trade-off in object versus spatial visualization abilities: restriction in the development of visual-processing resources. Psychon Bull Rev. 2010 Feb; 17(1):29-35. PMID: 20081157.
      Citations: 11     Fields:    Translation:Humans
    61. Wang Y, Becker M, Wang L, Liu J, Scholz R, Peng J, Christiansen S, Kim DH, Steinhart M, Gösele U. Nanostructured gold films for SERS by block copolymer-templated galvanic displacement reactions. Nano Lett. 2009 Jun; 9(6):2384-9. PMID: 19459615.
      Citations: 6     Fields:    
    62. Becker MA, Schumacher HR, Benjamin KL, Gorevic P, Greenwald M, Fessel J, Edwards L, Kawata AK, Frank L, Waltrip R, Maroli A, Huang B, Gout Natural History Study Group, Sundy JS. Quality of life and disability in patients with treatment-failure gout. J Rheumatol. 2009 May; 36(5):1041-8. PMID: 19332629.
      Citations: 63     Fields:    Translation:Humans
    63. Becker MA, Schumacher HR, MacDonald PA, Lloyd E, Lademacher C. Clinical efficacy and safety of successful longterm urate lowering with febuxostat or allopurinol in subjects with gout. J Rheumatol. 2009 Jun; 36(6):1273-82. PMID: 19286847.
      Citations: 84     Fields:    
    64. Chohan S, Becker MA. Update on emerging urate-lowering therapies. Curr Opin Rheumatol. 2009 Mar; 21(2):143-9. PMID: 19339925.
      Citations: 9     Fields:    Translation:Humans
    65. Schumacher HR, Becker MA, Lloyd E, MacDonald PA, Lademacher C. Febuxostat in the treatment of gout: 5-yr findings of the FOCUS efficacy and safety study. Rheumatology (Oxford). 2009 Feb; 48(2):188-94. PMID: 19141576.
      Citations: 71     Fields:    Translation:Humans
    66. Schumacher HR, Becker MA, Wortmann RL, Macdonald PA, Hunt B, Streit J, Lademacher C, Joseph-Ridge N. Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: a 28-week, phase III, randomized, double-blind, parallel-group trial. Arthritis Rheum. 2008 Nov 15; 59(11):1540-8. PMID: 18975369.
      Citations: 181     Fields:    Translation:HumansCTClinical Trials
    67. Furie R, Stohl W, Ginzler EM, Becker M, Mishra N, Chatham W, Merrill JT, Weinstein A, McCune WJ, Zhong J, Cai W, Freimuth W, Belimumab Study Group. Biologic activity and safety of belimumab, a neutralizing anti-B-lymphocyte stimulator (BLyS) monoclonal antibody: a phase I trial in patients with systemic lupus erythematosus. Arthritis Res Ther. 2008; 10(5):R109. PMID: 18786258; PMCID: PMC2592791.
      Citations: 83     Fields:    Translation:HumansCellsCTClinical Trials
    68. Sundy JS, Becker MA, Baraf HS, Barkhuizen A, Moreland LW, Huang W, Waltrip RW, Maroli AN, Horowitz Z, Pegloticase Phase 2 Study Investigators. Reduction of plasma urate levels following treatment with multiple doses of pegloticase (polyethylene glycol-conjugated uricase) in patients with treatment-failure gout: results of a phase II randomized study. Arthritis Rheum. 2008 Sep; 58(9):2882-91. PMID: 18759308.
      Citations: 56     Fields:    Translation:HumansCTClinical Trials
    69. O'Reilly DA, Witt H, Rahman SH, Schulz HU, Sargen K, Kage A, Cartmell MT, Landt O, Larvin M, Demaine AG, McMahon MJ, Becker M, Kingsnorth AN. The SPINK1 N34S variant is associated with acute pancreatitis. Eur J Gastroenterol Hepatol. 2008 Aug; 20(8):726-31. PMID: 18617776.
      Citations: 11     Fields:    Translation:Humans
    70. Walker AR, Komrokji RS, Ifthikharuddin J, Messina P, Mulford D, Becker M, Friedberg J, Oliva J, Phillips G, Liesveld JL, Abboud C. Phase I study of cladribine, cytarabine (Ara-C), granulocyte colony stimulating factor (G-CSF) (CLAG Regimen) and simultaneous escalating doses of imatinib mesylate (Gleevec) in relapsed/refractory AML. Leuk Res. 2008 Dec; 32(12):1830-6. PMID: 18571721.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    71. Laughlin TS, Becker MW, Liesveld JL, Mulford DA, Abboud CN, Brown P, Rothberg PG. Rapid method for detection of mutations in the nucleophosmin gene in acute myeloid leukemia. J Mol Diagn. 2008 Jul; 10(4):338-45. PMID: 18556765; PMCID: PMC2438203.
      Citations: 6     Fields:    Translation:Humans
    72. Becker MA, Sabina RL. PP07: new approaches, new knowledge, new challenges in human purine and pyrimidine metabolism. Nucleosides Nucleotides Nucleic Acids. 2008 Jun; 27(6):547-53. PMID: 18600501.
      Citations: 1     Fields:    Translation:Humans
    73. Becker MA, Friedmann T, Raivio KO, Hershfield MS, Nuki G. In memoriam: J. Edwin Seegmiller, M.D. (1920-2006). Nucleosides Nucleotides Nucleic Acids. 2008 Jun; 27(6):554-6. PMID: 18600502.
      Citations:    Fields:    Translation:Humans
    74. Becker MA, MacDonald PA, Hunt BJ, Lademacher C, Joseph-Ridge N. Determinants of the clinical outcomes of gout during the first year of urate-lowering therapy. Nucleosides Nucleotides Nucleic Acids. 2008 Jun; 27(6):585-91. PMID: 18600509.
      Citations: 28     Fields:    Translation:Humans
    75. Becker M, Erdmann N, Stegemann E, Benke D, Schauerte PN, Schaefer WM, Autschbach R, Kelm M, Koch KC. Survival and quality of life in patients with cardiac resynchronization therapy for severe heart failure and in heart transplant recipients within a contemporary heart failure management program. J Heart Lung Transplant. 2008 Jul; 27(7):746-52. PMID: 18582804.
      Citations: 3     Fields:    Translation:Humans
    76. Becker MA, Chohan S. We can make gout management more successful now. Curr Opin Rheumatol. 2008 Mar; 20(2):167-72. PMID: 18349746.
      Citations: 11     Fields:    Translation:Humans
    77. Taylor WJ, Schumacher HR, Baraf HS, Chapman P, Stamp L, Doherty M, McQueen F, Dalbeth N, Schlesinger N, Furst DE, Vazquez-Mellado J, Mellado JV, Becker MA, Kavanaugh A, Louthrenoo W, Bardin T, Khanna D, Simon LS, Yamanaka H, Choi HK, Zeng X, Strand V, Grainger R, Clegg D, Singh JA, Diaz-Torne C, Boers M, Gow P, Barskova VG. A modified Delphi exercise to determine the extent of consensus with OMERACT outcome domains for studies of acute and chronic gout. Ann Rheum Dis. 2008 Jun; 67(6):888-91. PMID: 18055475.
      Citations: 27     Fields:    Translation:Humans
    78. Schumacher HR, Taylor W, Joseph-Ridge N, Perez-Ruiz F, Chen LX, Schlesinger N, Khanna D, Furst DE, Becker MA, Dalbeth N, Edwards NL. Outcome evaluations in gout. J Rheumatol. 2007 Jun; 34(6):1381-5. PMID: 17552064.
      Citations: 11     Fields:    Translation:Humans
    79. Becker MA, Donn SM. Real-time pulmonary graphic monitoring. Clin Perinatol. 2007 Mar; 34(1):1-17, v. PMID: 17394927.
      Citations: 1     Fields:    Translation:Humans
    80. Chohan S, Becker MA. Does diuretic use increase the risk of recurrent gout flares? Nat Clin Pract Rheumatol. 2006 Dec; 2(12):650-1. PMID: 17133248.
      Citations: 1     Fields:    
    81. Becker MA, Jolly M. Hyperuricemia and associated diseases. Rheum Dis Clin North Am. 2006 May; 32(2):275-93, v-vi. PMID: 16716880.
      Citations: 35     Fields:    Translation:HumansAnimals
    82. Ellman MH, Becker MA. Crystal-induced arthropathies: recent investigative advances. Curr Opin Rheumatol. 2006 May; 18(3):249-55. PMID: 16582687.
      Citations: 3     Fields:    Translation:Humans
    83. Terkeltaub R, Bushinsky DA, Becker MA. Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics. Arthritis Res Ther. 2006; 8 Suppl 1:S4. PMID: 16820043; PMCID: PMC3226109.
      Citations: 46     Fields:    Translation:Humans
    84. Schumacher HR, Becker MA, Edwards NL, Palmer WE, MacDonald PA, Palo W, Joseph-Ridge N. Magnetic resonance imaging in the quantitative assessment of gouty tophi. Int J Clin Pract. 2006 Apr; 60(4):408-14. PMID: 16620352.
      Citations: 12     Fields:    Translation:Humans
    85. Becker MA, Schumacher HR, Wortmann RL, MacDonald PA, Eustace D, Palo WA, Streit J, Joseph-Ridge N. Febuxostat compared with allopurinol in patients with hyperuricemia and gout. N Engl J Med. 2005 Dec 08; 353(23):2450-61. PMID: 16339094.
      Citations: 367     Fields:    Translation:HumansCTClinical Trials
    86. Schumacher HR, Becker MA, Palo WA, Streit J, MacDonald PA, Joseph-Ridge N. Tophaceous gout: quantitative evaluation by direct physical measurement. J Rheumatol. 2005 Dec; 32(12):2368-72. PMID: 16331766.
      Citations: 11     Fields:    Translation:HumansCells
    87. Schumacher HR, Edwards LN, Perez-Ruiz F, Becker M, Chen LX, Furst DE, Joseph-Ridge N, Schlesinger N, Horowitz Z, Saag K, Boice JA, Yamanaka H, OMERACT 7 Special Interest Group. Outcome measures for acute and chronic gout. J Rheumatol. 2005 Dec; 32(12):2452-5. PMID: 16331785.
      Citations: 18     Fields:    Translation:Humans
    88. Uberti JP, Ayash L, Ratanatharathorn V, Silver S, Reynolds C, Becker M, Reddy P, Cooke KR, Yanik G, Whitfield J, Jones D, Hutchinson R, Braun T, Ferrara JL, Levine JE. Pilot trial on the use of etanercept and methylprednisolone as primary treatment for acute graft-versus-host disease. Biol Blood Marrow Transplant. 2005 Sep; 11(9):680-7. PMID: 16125638.
      Citations: 29     Fields:    Translation:HumansCTClinical Trials
    89. Becker MA, Schumacher HR, Wortmann RL, MacDonald PA, Palo WA, Eustace D, Vernillet L, Joseph-Ridge N. Febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase: a twenty-eight-day, multicenter, phase II, randomized, double-blind, placebo-controlled, dose-response clinical trial examining safety and efficacy in patients with gout. Arthritis Rheum. 2005 Mar; 52(3):916-23. PMID: 15751090.
      Citations: 73     Fields:    Translation:HumansCTClinical Trials
    90. Takano Y, Hase-Aoki K, Horiuchi H, Zhao L, Kasahara Y, Kondo S, Becker MA. Selectivity of febuxostat, a novel non-purine inhibitor of xanthine oxidase/xanthine dehydrogenase. Life Sci. 2005 Mar 04; 76(16):1835-47. PMID: 15698861.
      Citations: 81     Fields:    Translation:AnimalsCells
    91. Attar MA, Becker MA, Dechert RE, Donn SM. Immediate changes in lung compliance following natural surfactant administration in premature infants with respiratory distress syndrome: a controlled trial. J Perinatol. 2004 Oct; 24(10):626-30. PMID: 15201857.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    92. Becker MA, Kisicki J, Khosravan R, Wu J, Mulford D, Hunt B, MacDonald P, Joseph-Ridge N. Febuxostat (TMX-67), a novel, non-purine, selective inhibitor of xanthine oxidase, is safe and decreases serum urate in healthy volunteers. Nucleosides Nucleotides Nucleic Acids. 2004 Oct; 23(8-9):1111-6. PMID: 15571211.
      Citations: 27     Fields:    Translation:HumansCTClinical Trials
    93. Kelly D, Jara P, Rodeck B, Lykavieris P, Burdelski M, Becker M, Gridelli B, Boillot O, Manzanares J, Reding R. Tacrolimus and steroids versus ciclosporin microemulsion, steroids, and azathioprine in children undergoing liver transplantation: randomised European multicentre trial. Lancet. 2004 Sep 18-24; 364(9439):1054-61. PMID: 15380964.
      Citations: 17     Fields:    Translation:HumansCTClinical Trials
    94. Cooper A, Galbreath N, Becker MA. Sex on the internet: furthering our understanding of men with online sexual problems. Psychol Addict Behav. 2004 Sep; 18(3):223-30. PMID: 15482077.
      Citations: 4     Fields:    Translation:Humans
    95. Riedel AA, Nelson M, Joseph-Ridge N, Wallace K, MacDonald P, Becker M. Compliance with allopurinol therapy among managed care enrollees with gout: a retrospective analysis of administrative claims. J Rheumatol. 2004 Aug; 31(8):1575-81. PMID: 15290738.
      Citations: 50     Fields:    Translation:Humans
    96. Ratanatharathorn V, Ayash L, Reynolds C, Silver S, Reddy P, Becker M, Ferrara JL, Uberti JP. Treatment of chronic graft-versus-host disease with anti-CD20 chimeric monoclonal antibody. Biol Blood Marrow Transplant. 2003 Aug; 9(8):505-11. PMID: 12931119.
      Citations: 67     Fields:    Translation:HumansCells
    97. Torres RJ, Rivero M, Ahmed M, Becker MA, García-Pavía P, García-Puig J. Phosphoribosylpyrophosphate synthetase overactivity as a cause of uric acid overproduction in a young woman. Arthritis Rheum. 2003 Jul; 48(7):2036-41. PMID: 12847698.
      Citations: 11     Fields:    Translation:Humans
    98. Klapman JB, Ene-Stroescu D, Becker MA, Hanauer SB. A lupus-like syndrome associated with infliximab therapy. Inflamm Bowel Dis. 2003 May; 9(3):176-8. PMID: 12792223.
      Citations: 8     Fields:    Translation:Humans
    99. Choi-Sledeski YM, Kearney R, Poli G, Pauls H, Gardner C, Gong Y, Becker M, Davis R, Spada A, Liang G, Chu V, Brown K, Collussi D, Leadley R, Rebello S, Moxey P, Morgan S, Bentley R, Kasiewski C, Maignan S, Guilloteau JP, Mikol V. Discovery of an orally efficacious inhibitor of coagulation factor Xa which incorporates a neutral P1 ligand. J Med Chem. 2003 Feb 27; 46(5):681-4. PMID: 12593648.
      Citations: 5     Fields:    Translation:AnimalsCells
    100. Bhatia E, Choudhuri G, Sikora SS, Landt O, Kage A, Becker M, Witt H, Bhatia E, Choudhuri G, Sikora SS, Landt O, Kage A, Becker M, Witt H. Tropical calcific pancreatitis: strong association with SPINK1 trypsin inhibitor mutations. Gastroenterology. 2002 Oct; 123(4):1020-5. PMID: 12360463.
      Citations: 46     Fields:    Translation:Humans
    101. Oca MJ, Becker MA, Dechert RE, Donn SM, Oca MJ, Becker MA, Dechert RE, Donn SM. Relationship of neonatal endotracheal tube size and airway resistance. Respir Care. 2002 Sep; 47(9):994-7. PMID: 12188933.
      Citations: 2     Fields:    Translation:Humans
    102. Rezai KA, Patel SC, Eliott D, Becker MA. Rheumatoid hyperviscosity syndrome: reversibility of microvascular abnormalities after treatment. Am J Ophthalmol. 2002 Jul; 134(1):130-2. PMID: 12095825.
      Citations: 1     Fields:    Translation:Humans
    103. Truninger K, Witt H, Kage A, Seifert B, Ammann RW, Blum HE, Becker M, Köck J. Mutations of the serine protease inhibitor, Kazal type 1 gene, in patients with idiopathic chronic pancreatitis. Am J Gastroenterol. 2002 May; 97(5):1133-7. PMID: 12014716.
      Citations: 17     Fields:    Translation:Humans
    104. Becker MA. Phosphoribosylpyrophosphate synthetase and the regulation of phosphoribosylpyrophosphate production in human cells. Prog Nucleic Acid Res Mol Biol. 2001; 69:115-48. PMID: 11550793.
      Citations: 25     Fields:    Translation:HumansCells
    105. Tung BJ, Becker MA. Modes of neonatal and pediatric ventilation. Air Med J. 2001 Jan-Feb; 20(1):12-3. PMID: 11182698.
      Citations:    Fields:    Translation:Humans
    106. Becker MA, Ahmed M. Cell type-specific differential expression of human PRPP synthetase (PRPS) genes. Adv Exp Med Biol. 2000; 486:5-10. PMID: 11783526.
      Citations: 3     Fields:    Translation:HumansAnimals
    107. Ahmed M, Taylor W, Smith PR, Becker MA. Accelerated transcription of PRPS1 in X-linked overactivity of normal human phosphoribosylpyrophosphate synthetase. J Biol Chem. 1999 Mar 12; 274(11):7482-8. PMID: 10066814.
      Citations: 14     Fields:    Translation:HumansCells
    108. Wilson BJ, Becker MA, Linton ME, Donn SM. Spontaneous minute ventilation predicts readiness for extubation in mechanically ventilated preterm infants. J Perinatol. 1998 Nov-Dec; 18(6 Pt 1):436-9. PMID: 9848756.
      Citations: 3     Fields:    Translation:Humans
    109. Becker MA, Taylor W, Smith PR, Ahmed M. Regulation of human PRS isoform expression. Adv Exp Med Biol. 1998; 431:215-20. PMID: 9598062.
      Citations:    Fields:    Translation:HumansCells
    110. Nelson M, Nicks JJ, Becker MA, Vrlenich LA, Bhatt-Mehta V, Schumacher RE. Comparison of two methods of surfactant administration and the effect on dosing-associated hypoxemia. J Perinatol. 1997 Nov-Dec; 17(6):450-4. PMID: 9447531.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    111. Becker MA, Taylor W, Smith PR, Ahmed M. Overexpression of the normal phosphoribosylpyrophosphate synthetase 1 isoform underlies catalytic superactivity of human phosphoribosylpyrophosphate synthetase. J Biol Chem. 1996 Aug 16; 271(33):19894-9. PMID: 8702702.
      Citations: 13     Fields:    Translation:HumansCells
    112. Attar MA, Becker MA, Nicks JJ, Faix RG. Ventilatory management casebook. Successful treatment of pulmonary interstitial emphysema with high-frequency oscillation after unsuccessful high-frequency jet ventilation. J Perinatol. 1996 May-Jun; 16(3 Pt 1):222-30. PMID: 8817438.
      Citations:    Fields:    Translation:Humans
    113. Torres RJ, Mateos FA, Puig JG, Becker MA. Determination of phosphoribosylpyrophosphate synthetase activity in human cells by a non-isotopic, one step method. Clin Chim Acta. 1996 Feb 09; 245(1):105-12. PMID: 8646809.
      Citations: 5     Fields:    Translation:HumansCells
    114. Becker MA, Smith PR, Taylor W, Mustafi R, Switzer RL. The genetic and functional basis of purine nucleotide feedback-resistant phosphoribosylpyrophosphate synthetase superactivity. J Clin Invest. 1995 Nov; 96(5):2133-41. PMID: 7593598; PMCID: PMC185862.
      Citations: 30     Fields:    Translation:HumansCells
    115. Fry DW, Becker MA, Switzer RL. Inhibition of human 5-phosphoribosyl-1-pyrophosphate synthetase by 4-amino-8-(beta-D-ribofuranosylamino)-pyrimido[5,4-d]pyrimidine-5'- monophosphate: evidence for interaction at the ADP allosteric site. Mol Pharmacol. 1995 Apr; 47(4):810-5. PMID: 7723742.
      Citations: 10     Fields:    Translation:HumansCells
    116. Nicks JJ, Becker MA, Donn SM. Ventilatory management casebook. Bronchopulmonary dysplasias. Response to pressure support ventilation. J Perinatol. 1994 Nov-Dec; 14(6):495-7. PMID: 7876945.
      Citations: 2     Fields:    Translation:Humans
    117. Donn SM, Nicks JJ, Becker MA. Flow-synchronized ventilation of preterm infants with respiratory distress syndrome. J Perinatol. 1994 Mar-Apr; 14(2):90-4. PMID: 8014707.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    118. Torres RJ, Mateos FA, Puig JG, Becker MA. A simplified method for the determination of phosphoribosylpyrophosphate synthetase activity in hemolysates. Clin Chim Acta. 1994 Jan 14; 224(1):55-63. PMID: 8174278.
      Citations: 4     Fields:    Translation:Humans
    119. Torres R, Mateos F, Puig JG, Becker MA. Determination of the activity of recombinant human phosphoribosylpyrophosphate synthetase isoform 1 by a non-isotopic, one-step method. Adv Exp Med Biol. 1994; 370:821-4. PMID: 7661031.
      Citations:    Fields:    Translation:Humans
    120. Becker MA, Nosal JM, Switzer RL, Smith PR, Palella TD, Roessler BJ. Point mutations in PRPS1, the gene encoding the PRPP synthetase (PRS) 1 isoform, underlie X-linked PRS superactivity associated with purine nucleotide inhibitor-resistance. Adv Exp Med Biol. 1994; 370:707-10. PMID: 7661003.
      Citations: 3     Fields:    Translation:HumansCells
    121. Roessler BJ, Nosal JM, Smith PR, Heidler SA, Palella TD, Switzer RL, Becker MA. Human X-linked phosphoribosylpyrophosphate synthetase superactivity is associated with distinct point mutations in the PRPS1 gene. J Biol Chem. 1993 Dec 15; 268(35):26476-81. PMID: 8253776.
      Citations: 15     Fields:    Translation:HumansCells
    122. Nosal JM, Switzer RL, Becker MA. Overexpression, purification, and characterization of recombinant human 5-phosphoribosyl-1-pyrophosphate synthetase isozymes I and II. J Biol Chem. 1993 May 15; 268(14):10168-75. PMID: 8387514.
      Citations: 27     Fields:    Translation:HumansCells
    123. Nicks JJ, Becker MA, Donn SM. Ventilatory management casebook. Neonatal respiratory failure: response to volume ventilation. J Perinatol. 1993 Jan-Feb; 13(1):72-5. PMID: 8445451.
      Citations:    Fields:    Translation:Humans
    124. Becker MA, Kim M, Husain K, Kang T. Regulation of purine nucleotide synthesis in human B lymphoblasts with both hypoxanthine-guanine phosphoribosyltransferase deficiency and phosphoribosylpyrophosphate synthetase superactivity. J Biol Chem. 1992 Mar 05; 267(7):4317-21. PMID: 1311306.
      Citations: 1     Fields:    Translation:HumansCells
    125. Wang JC, Passage MB, Ellison J, Becker MA, Yen PH, Shapiro LJ, Mohandas TK. Physical mapping of loci in the distal half of the short arm of the human X chromosome: implications for the spreading of X-chromosome inactivation. Somat Cell Mol Genet. 1992 Mar; 18(2):195-200. PMID: 1315458.
      Citations: 3     Fields:    Translation:HumansCells
    126. Roessler BJ, Golovoy N, Palella TD, Heidler S, Becker MA. Identification of distinct PRS1 mutations in two patients with X-linked phosphoribosylpyrophosphate synthetase superactivity. Adv Exp Med Biol. 1991; 309B:125-8. PMID: 1664177.
      Citations: 9     Fields:    Translation:HumansCells
    127. Becker MA, Heidler SA, Nosal JM, Switzer RL, LeBeau MM, Shapiro LJ, Palella TD, Roessler BJ. Human phosphoribosylpyrophosphate synthetase (PRS) 2: an independent active, X chromosome-linked PRS isoform. Adv Exp Med Biol. 1991; 309B:129-32. PMID: 1723569.
      Citations: 1     Fields:    Translation:HumansCells
    128. Becker MA, Heidler SA, Bell GI, Seino S, Le Beau MM, Westbrook CA, Neuman W, Shapiro LJ, Mohandas TK, Roessler BJ, et al. Cloning of cDNAs for human phosphoribosylpyrophosphate synthetases 1 and 2 and X chromosome localization of PRPS1 and PRPS2 genes. Genomics. 1990 Nov; 8(3):555-61. PMID: 1962753.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    129. Becker MA. Rheumatology. JAMA. 1989 May 19; 261(19):2887-8. PMID: 2709595.
      Citations:    Fields:    Translation:Humans
    130. Puig JG, Mateos FA, Ramos TH, Nieto VG, Becker MA, Jiménez ML, Melián JS. Increased purine nucleotide degradation in the central nervous system (CNS) in PRPP synthetase superactivity. Adv Exp Med Biol. 1989; 253A:9-13. PMID: 2560341.
      Citations: 3     Fields:    Translation:Humans
    131. Becker MA, Kim M, Husain K. PRPP and purine nucleotide metabolism in human lymphoblasts with both PRPP synthetase superactivity and HGPRT deficiency. Adv Exp Med Biol. 1989; 253B:13-20. PMID: 2481968.
      Citations: 1     Fields:    Translation:HumansCells
    132. Becker MA, Puig JG, Mateos FA, Jimenez ML, Kim M, Simmonds HA. Neurodevelopmental impairment and deranged PRPP and purine nucleotide synthesis in inherited superactivity of PRPP synthetase. Adv Exp Med Biol. 1989; 253A:15-22. PMID: 2483028.
      Citations: 2     Fields:    Translation:HumansCells
    133. Becker MA, Puig JG, Mateos FA, Jimenez ML, Kim M, Simmonds HA. Inherited superactivity of phosphoribosylpyrophosphate synthetase: association of uric acid overproduction and sensorineural deafness. Am J Med. 1988 Sep; 85(3):383-90. PMID: 2843048.
      Citations: 19     Fields:    Translation:HumansCells
    134. Becker MA. Clinical aspects of monosodium urate monohydrate crystal deposition disease (gout). Rheum Dis Clin North Am. 1988 Aug; 14(2):377-94. PMID: 3051156.
      Citations: 8     Fields:    Translation:Humans
    135. Carragher B, Bluemke DA, Becker M, McDade WA, Potel MJ, Josephs R. Structural analysis of polymers of sickle cell hemoglobin. III. Fibers within fascicles. J Mol Biol. 1988 Jan 20; 199(2):383-8. PMID: 3351930.
      Citations: 1     Fields:    Translation:Humans
    136. Becker MA, Kim M. Regulation of purine synthesis de novo in human fibroblasts by purine nucleotides and phosphoribosylpyrophosphate. J Biol Chem. 1987 Oct 25; 262(30):14531-7. PMID: 2444588.
      Citations: 14     Fields:    Translation:HumansCells
    137. Becker MA, Losman MJ, Kim M. Mechanisms of accelerated purine nucleotide synthesis in human fibroblasts with superactive phosphoribosylpyrophosphate synthetases. J Biol Chem. 1987 Apr 25; 262(12):5596-602. PMID: 3032938.
      Citations: 13     Fields:    Translation:HumansCells
    138. Becker MA, Losman MJ, Rosenberg AL, Mehlman I, Levinson DJ, Holmes EW. Phosphoribosylpyrophosphate synthetase superactivity. A study of five patients with catalytic defects in the enzyme. Arthritis Rheum. 1986 Jul; 29(7):880-8. PMID: 3017368.
      Citations: 6     Fields:    Translation:HumansCells
    139. Becker MA, Losman MJ, Wilson J, Simmonds HA. Superactivity of human phosphoribosyl pyrophosphate synthetase due to altered regulation by nucleotide inhibitors and inorganic phosphate. Biochim Biophys Acta. 1986 Jun 19; 882(2):168-76. PMID: 2423135.
      Citations: 8     Fields:    Translation:HumansCells
    140. Becker MA, Losman MJ, Rimon D, Kim M. PRPP synthetase superactivity in lymphoblast lines. Adv Exp Med Biol. 1986; 195 Pt A:51-8. PMID: 3014839.
      Citations: 1     Fields:    Translation:HumansCells
    141. Becker MA, Losman MJ, Simmonds HA. Inherited phosphoribosylpyrophosphate synthetase superactivity due to aberrant inhibitor and activator responsiveness. Adv Exp Med Biol. 1986; 195 Pt A:59-66. PMID: 3014841.
      Citations: 1     Fields:    Translation:HumansCells
    142. Losman MJ, Rimon D, Kim M, Becker MA. Selective expression of phosphoribosylpyrophosphate synthetase superactivity in human lymphoblast lines. J Clin Invest. 1985 Oct; 76(4):1657-64. PMID: 2414323; PMCID: PMC424156.
      Citations: 1     Fields:    Translation:HumansCells
    143. Itkin P, Woo S, Becker MA. Human phosphoribosylpyrophosphate synthetase: radioimmunochemical quantitation in erythrocytes and fibroblasts. J Lab Clin Med. 1984 Jul; 104(1):96-109. PMID: 6330252.
      Citations: 1     Fields:    Translation:HumansCells
    144. Losman MJ, Hecker S, Woo S, Becker MA. Diagnostic evaluation of phosphoribosylpyrophosphate synthetase activities in hemolysates. J Lab Clin Med. 1984 Jun; 103(6):932-43. PMID: 6327865.
      Citations: 3     Fields:    Translation:HumansCells
    145. Sabina RL, Holmes EW, Becker MA. The enzymatic synthesis of 5-amino-4-imidazolecarboxamide riboside triphosphate (ZTP). Science. 1984 Mar 16; 223(4641):1193-5. PMID: 6199843.
      Citations: 27     Fields:    Translation:AnimalsCells
    146. Becker MA, Itkin P. Radioimmunoassay studies of human phosphoribosylpyrophosphate synthetase. Adv Exp Med Biol. 1984; 165 Pt B:5-10. PMID: 6326507.
      Citations:    Fields:    Translation:HumansCells
    147. Losman MJ, Becker MA. Human phosphoribosylpyrophosphate (PRPP) synthetase requirements for subunit aggregation. Adv Exp Med Biol. 1984; 165 Pt A:427-32. PMID: 6326486.
      Citations: 1     Fields:    Translation:HumansCells
    148. Becker MA. Phosphoribosylpyrophosphate synthetase superactivity: detection, characterization of underlying defects, and treatment. Adv Exp Med Biol. 1984; 165 Pt A:91-96. PMID: 6326492.
      Citations: 1     Fields:    Translation:HumansCells
    149. Becker MA, Dicker P, Rozengurt E. Mitogenic enhancement of purine base phosphoribosylation in Swiss mouse 3T3 cells. Am J Physiol. 1983 Mar; 244(3):C288-96. PMID: 6187219.
      Citations: 4     Fields:    Translation:AnimalsCells
    150. Becker MA, Losman MJ, Itkin P, Simkin PA. Gout with superactive phosphoribosylpyrophosphate synthetase due to increased enzyme catalytic rate. J Lab Clin Med. 1982 Apr; 99(4):495-511. PMID: 6174658.
      Citations: 9     Fields:    Translation:HumansCells
    151. Raivio KO, Lazar CS, Krumholz HR, Becker MA. The phosphogluconate pathway and synthesis of 5-phosphoribosyl-1-pyrophosphate in human fibroblasts. Biochim Biophys Acta. 1981 Nov 18; 678(1):51-7. PMID: 6171305.
      Citations: 3     Fields:    Translation:HumansCells
    152. Raivio KO, Lazar CS, Becker MA. Regulation of 5-phosphoribosyl-1-pyrophosphate synthesis in human fibroblasts by the concentration of inorganic phosphate. Biochim Biophys Acta. 1981 Nov 18; 678(1):58-64. PMID: 6171306.
      Citations: 5     Fields:    Translation:HumansCells
    153. Yen RC, Raivio KO, Becker MA. Inhibition of phosphoribosylpyrophosphate synthesis in human fibroblasts by 6-methylthioinosinate. J Biol Chem. 1981 Feb 25; 256(4):1839-45. PMID: 6257688.
      Citations: 3     Fields:    Translation:HumansCells
    154. Becker MA, Raivio KO, Bakay B, Adams WB, Nyhan WL. Superactive phosphoribosylpyrophosphate synthetase with altered regulatory and catalytic properties. Adv Exp Med Biol. 1980; 122A:387-92. PMID: 6158850.
      Citations: 2     Fields:    Translation:HumansCells
    155. Becker MA, Raivio KO, Bakay B, Adams WB, Nyhan WL. Variant human phosphoribosylpyrophosphate synthetase altered in regulatory and catalytic functions. J Clin Invest. 1980 Jan; 65(1):109-20. PMID: 6243137; PMCID: PMC371345.
      Citations: 22     Fields:    Translation:HumansCells
    156. Huisman WH, Raivio KO, Becker MA. Simultaneous estimation of rates of pyrimidine and purine nucleotide synthesis de novo in cultured human cells. J Biol Chem. 1979 Dec 25; 254(24):12595-602. PMID: 500731.
      Citations: 4     Fields:    Translation:HumansCells
    157. Becker MA, Yen RC, Itkin P, Goss SJ, Seegmiller JE, Bakay B. Regional localization of the gene for human phosphoribosylpyrophosphate synthetase on the X chromosome. Science. 1979 Mar 09; 203(4384):1016-9. PMID: 218284.
      Citations: 10     Fields:    Translation:HumansCells
    158. Yen RC, Becker MA. Methylmercaptopurine ribonucleoside toxicity in human fibroblasts: inhibition of phosphoribosylpyrophosphate synthetase as well as amidophosphoribosyltransferase. Adv Exp Med Biol. 1979; 122B:137-43. PMID: 232627.
      Citations: 1     Fields:    Translation:HumansCells
    159. Becker MA, Raivio KO, Seegmiller JE. Synthesis of phosphoribosylpyrophosphate in mammalian cells. Adv Enzymol Relat Areas Mol Biol. 1979; 49:281-306. PMID: 95664.
      Citations: 19     Fields:    Translation:HumansAnimals
    160. Huisman WH, Raivio KO, Becker MA. Simultaneous determination of rates of purine and pyrimidine synthesis in cultured human lymphoblasts and fibroblasts. Adv Exp Med Biol. 1979; 122B:223-9. PMID: 546147.
      Citations: 2     Fields:    Translation:HumansCells
    161. Raivio KO, Lazar C, Krumholz H, Becker MA. Determinants of 5-phosphoribosyl-1-pyrophosphate (PRPP) synthesis in human fibroblasts. Adv Exp Med Biol. 1979; 122B:31-4. PMID: 94761.
      Citations: 1     Fields:    Translation:HumansCells
    162. Yen RC, Adams WB, Lazar C, Becker MA. Evidence for X-linkage of human phosphoribosylpyrophosphate synthetase. Proc Natl Acad Sci U S A. 1978 Jan; 75(1):482-5. PMID: 203941; PMCID: PMC411274.
      Citations: 8     Fields:    Translation:HumansCells
    163. Weintraub M, Nash TE, Ottesen E, Becker MA. Uricosuric effects of niridazole. Clin Pharmacol Ther. 1977 Nov; 22(5 Pt 1):568-72. PMID: 913024.
      Citations:    Fields:    Translation:Humans
    164. Meyer LJ, Becker MA. Human erythrocyte phosphoribosylpyrophosphate synthetase. Dependence of activity on state of subunit association. J Biol Chem. 1977 Jun 10; 252(11):3919-25. PMID: 193850.
      Citations: 8     Fields:    Translation:HumansCells
    165. Becker MA, Meyer LJ, Huisman WH, Lazar C, Adams WB. Human erythrocyte phosphoribosylpyrophosphate synthetase. Subunit analysis and states of subunit association. J Biol Chem. 1977 Jun 10; 252(11):3911-8. PMID: 193849.
      Citations: 9     Fields:    Translation:HumansCells
    166. Becker MA, Meyer LJ, Huisman WH, Lazar CS, Adams WB. Human phosphoribosylpyrophosphate synthetase: relation of activity and quaternary structure. Adv Exp Med Biol. 1977; 76A:71-9. PMID: 193379.
      Citations:    Fields:    Translation:HumansCells
    167. Becker MA. Fibroblast phosphoribosylpyrophosphate and ribose-5-phosphate concentration and generation in gout with purine overproduction. Adv Exp Med Biol. 1977; 76A:270-9. PMID: 193370.
      Citations: 1     Fields:    Translation:HumansCells
    168. Sweetman L, Borden M, Lesh P, Bakay B, Becker MA. Diminished affinity for purine substrates as a basis for gout with mild deficiency of hypoxanthine-guanine phosphoribosyltransferase. Adv Exp Med Biol. 1977; 76A:319-25. PMID: 558714.
      Citations:    Fields:    Translation:HumansCells
    169. Becker MA. Effects of inosine on purine synthesis in normal and HGPRT-deficient human fibroblasts. Adv Exp Med Biol. 1977; 76A:370-5. PMID: 857618.
      Citations:    Fields:    Translation:HumansCells
    170. Bakay B, Becker MA, Nyhan WL. Reaction of antibody to normal human hypoxanthine phosphoribosyltransferase with products of mutant genes. Arch Biochem Biophys. 1976 Dec; 177(2):415-26. PMID: 1035076.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    171. Dwosh IL, Resnick D, Becker MA. Hip involvement in ankylosing spondylitis. Arthritis Rheum. 1976 Jul-Aug; 19(4):683-92. PMID: 942499.
      Citations: 14     Fields:    Translation:Humans
    172. Becker MA. Regulation of purine nucleotide synthesis. Effects of inosine on normal and hypoxantine-guanine phosphoribosyltransferase-deficient fibroblasts. Biochim Biophys Acta. 1976 Jun 18; 435(2):132-44. PMID: 938674.
      Citations: 4     Fields:    Translation:HumansCells
    173. Becker MA. Patterns of phosphoribosylpyrophosphate and ribose-5-phosphate concentration and generation in fibroblasts from patients with gout and purine overproduction. J Clin Invest. 1976 Feb; 57(2):308-18. PMID: 176178; PMCID: PMC436655.
      Citations: 15     Fields:    Translation:HumansCells
    174. Becker MA, Seegmiller JE. Recent advances in the identification of enzyme abnormalities underlying excessive purine synthesis in man. Arthritis Rheum. 1975 Nov-Dec; 18(6 Suppl):687-94. PMID: 173346.
      Citations: 5     Fields:    Translation:Humans
    175. Becker MA, Argubright KF, Seegmiller JE. Effects of oxipurinol on pyrimidine nucleotide synthesis in human lymphoblasts. Arthritis Rheum. 1975 Nov-Dec; 18(6 Suppl):871-6. PMID: 1201132.
      Citations: 1     Fields:    Translation:HumansCells
    176. Becker MA, Kostel PJ, Meyer LJ. Human phosphoribosylpyrophosphate synthetase. Comparison of purified normal and mutant enzymes. J Biol Chem. 1975 Sep 10; 250(17):6822-30. PMID: 169259.
      Citations: 15     Fields:    Translation:HumansCells
    177. Johnson MG, Rosenweig S, Switzer RL, Becker MA, Seegmiller JE. Evaluation of the role of 5-phosphoribosyl-alpha-1-pyrophosphate synthetase in congenital hyperuricemia and gout: a simple isotopic assay and an activity stain for the enzyme. Biochem Med. 1974 Jul; 10(3):266-75. PMID: 4366297.
      Citations: 6     Fields:    Translation:HumansCells
    178. Becker MA, Seegmiller JE. Genetic aspects of gout. Annu Rev Med. 1974; 25(0):15-28. PMID: 4604505.
      Citations: 3     Fields:    Translation:HumansCells
    179. Wood AW, Becker MA, Minna JD, Seegmiller JE. Purine metabolism in normal and thioguanine-resistant neuroblastoma. Proc Natl Acad Sci U S A. 1973 Dec; 70(12):3880-3. PMID: 4521214; PMCID: PMC427349.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    180. Becker MA, Kostel PJ, Meyer LJ, Seegmiller JE. Human phosphoribosylpyrophosphate synthetase: increased enzyme specific activity in a family with gout and excessive purine synthesis. Proc Natl Acad Sci U S A. 1973 Oct; 70(10):2749-52. PMID: 4200723; PMCID: PMC427101.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    181. Becker MA, Meyer LJ, Seegmiller JE. Gout with purine overproduction due to increased phosphoribosylpyrophosphate synthetase activity. Am J Med. 1973 Aug; 55(2):232-42. PMID: 4722859.
      Citations: 20     Fields:    Translation:HumansCells
    182. Wood AW, Becker MA, Seegmiller JE. Purine nucleotide synthesis in lymphoblasts cultured from normal subjects and a patient with Lesch-Nyhan syndrome. Biochem Genet. 1973 Jul; 9(3):261-74. PMID: 4354564.
      Citations: 15     Fields:    Translation:HumansCells
    183. Becker MA, Meyer LJ, Wood AW, Seegmiller JE. Purine overproduction in man associated with increased phosphoribosylpyrophosphate synthetase activity. Science. 1973 Mar 16; 179(4078):1123-6. PMID: 4347565.
      Citations: 26     Fields:    Translation:HumansCells
    184. Becker MA, Meyer LJ, Kostel PJ, Seegmiller JE. Increased PP-ribose-P synthetase activity: a genetic abnormality leading to excessive purine production and gout. Adv Exp Med Biol. 1973; 41:307-15. PMID: 4364688.
      Citations:    Fields:    Translation:HumansCells
    185. Boyle JA, Raivio KO, Becker MA, Seegmiller JE. Effects of nicotinic acid on human fibroblast purine biosynthesis. Biochim Biophys Acta. 1972 May 10; 269(2):179-83. PMID: 4337750.
      Citations: 10     Fields:    Translation:HumansCells
    Becker's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (684)
    Explore
    _
    Co-Authors (3)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _
    Physical Neighbors
    _