Joseph Thornton to Ligands
This is a "connection" page, showing publications Joseph Thornton has written about Ligands.
Connection Strength
1.643
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Evolution of minimal specificity and promiscuity in steroid hormone receptors. PLoS Genet. 2012; 8(11):e1003072.
Score: 0.350
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Protein evolution by molecular tinkering: diversification of the nuclear receptor superfamily from a ligand-dependent ancestor. PLoS Biol. 2010 Oct 05; 8(10).
Score: 0.302
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A hydrophobic ratchet entrenches molecular complexes. Nature. 2020 12; 588(7838):503-508.
Score: 0.153
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Evolution of protein specificity: insights from ancestral protein reconstruction. Curr Opin Struct Biol. 2017 12; 47:113-122.
Score: 0.122
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Vestigialization of an allosteric switch: genetic and structural mechanisms for the evolution of constitutive activity in a steroid hormone receptor. PLoS Genet. 2014 Jan; 10(1):e1004058.
Score: 0.095
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Biophysical mechanisms for large-effect mutations in the evolution of steroid hormone receptors. Proc Natl Acad Sci U S A. 2013 Jul 09; 110(28):11475-80.
Score: 0.091
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Lamprey endocrinology is not ancestral. Proc Natl Acad Sci U S A. 2011 Jan 11; 108(2):E5; author reply E6.
Score: 0.077
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Evolution of steroid receptors from an estrogen-sensitive ancestral receptor. Mol Cell Endocrinol. 2011 Mar 01; 334(1-2):31-8.
Score: 0.075
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Evolution of hormone signaling in elasmobranchs by exploitation of promiscuous receptors. Mol Biol Evol. 2008 Dec; 25(12):2643-52.
Score: 0.066
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Crystal structure of an ancient protein: evolution by conformational epistasis. Science. 2007 Sep 14; 317(5844):1544-8.
Score: 0.061
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The Octopus vulgaris estrogen receptor is a constitutive transcriptional activator: evolutionary and functional implications. Endocrinology. 2006 Aug; 147(8):3861-9.
Score: 0.056
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Evolution of hormone-receptor complexity by molecular exploitation. Science. 2006 Apr 07; 312(5770):97-101.
Score: 0.055
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Resurrecting the ancestral steroid receptor: ancient origin of estrogen signaling. Science. 2003 Sep 19; 301(5640):1714-7.
Score: 0.046
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Evolution of vertebrate steroid receptors from an ancestral estrogen receptor by ligand exploitation and serial genome expansions. Proc Natl Acad Sci U S A. 2001 May 08; 98(10):5671-6.
Score: 0.039
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Evolution of the androgen receptor: structure-function implications. Bioessays. 1998 Oct; 20(10):860-9.
Score: 0.033
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Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1. Cell. 2005 Feb 11; 120(3):343-55.
Score: 0.013
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Identification of a third distinct estrogen receptor and reclassification of estrogen receptors in teleosts. Proc Natl Acad Sci U S A. 2000 Sep 26; 97(20):10751-6.
Score: 0.009