"Ligands" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g., an antigen binding to an antibody, a hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme. Ligands are also molecules that donate or accept a pair of electrons to form a coordinate covalent bond with the central metal atom of a coordination complex. (From Dorland, 27th ed)
Descriptor ID |
D008024
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MeSH Number(s) |
D27.720.470.480
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ligands".
Below are MeSH descriptors whose meaning is more specific than "Ligands".
This graph shows the total number of publications written about "Ligands" by people in this website by year, and whether "Ligands" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 3 | 3 |
1995 | 0 | 3 | 3 |
1996 | 0 | 6 | 6 |
1997 | 0 | 8 | 8 |
1998 | 1 | 6 | 7 |
1999 | 0 | 7 | 7 |
2000 | 0 | 9 | 9 |
2001 | 0 | 10 | 10 |
2002 | 0 | 15 | 15 |
2003 | 0 | 21 | 21 |
2004 | 0 | 12 | 12 |
2005 | 2 | 14 | 16 |
2006 | 0 | 12 | 12 |
2007 | 0 | 17 | 17 |
2008 | 0 | 12 | 12 |
2009 | 1 | 20 | 21 |
2010 | 1 | 9 | 10 |
2011 | 0 | 7 | 7 |
2012 | 2 | 18 | 20 |
2013 | 0 | 11 | 11 |
2014 | 0 | 12 | 12 |
2015 | 0 | 13 | 13 |
2016 | 0 | 12 | 12 |
2017 | 1 | 10 | 11 |
2018 | 0 | 12 | 12 |
2019 | 0 | 8 | 8 |
2020 | 1 | 16 | 17 |
2021 | 0 | 8 | 8 |
2022 | 0 | 14 | 14 |
2023 | 0 | 9 | 9 |
2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "Ligands" by people in Profiles.
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Delivery of loaded MR1 monomer results in efficient ligand exchange to host MR1 and subsequent MR1T cell activation. Commun Biol. 2024 Feb 24; 7(1):228.
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Immunogenic Bifunctional Nanoparticle Suppresses Programmed Cell Death-Ligand 1 in Cancer and Dendritic Cells to Enhance Adaptive Immunity and Chemo-Immunotherapy. ACS Nano. 2024 Feb 13; 18(6):5152-5166.
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Potential Dietary and Therapeutic Strategies Involving Indole-3-Carbinole in Preclinical Models of Intestinal Inflammation. Nutrients. 2023 Nov 30; 15(23).
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A simplified protocol for the automated production of 2-[18 F]fluoro-3-[2-((S)-3-pyrrolinyl)methoxy]pyridine ([18 F]nifene) on an IBA Synthera® module. J Labelled Comp Radiopharm. 2024 Jan; 67(1):31-36.
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Evaluation of an Image-Derived Input Function for Kinetic Modeling of Nicotinic Acetylcholine Receptor-Binding PET Ligands in Mice. Int J Mol Sci. 2023 Oct 24; 24(21).
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Commensal bacteria signal through TLR5 and AhR to improve barrier integrity and prevent allergic responses to food. Cell Rep. 2023 10 31; 42(10):113153.
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Development of Masitinib Derivatives with Enhanced Mpro Ligand Efficiency and Reduced Cytotoxicity. Molecules. 2023 Sep 15; 28(18).
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EZH2 activates Wnt/ß-catenin signaling in human uterine fibroids, which is inhibited by the natural compound methyl jasmonate. F S Sci. 2023 08; 4(3):239-256.
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Understanding Long-Term Survival of Patients with Ovarian Cancer-The Tumor Microenvironment Comes to the Forefront. Cancer Res. 2023 05 02; 83(9):1383-1385.
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Predicting the Development of Renal Replacement Therapy Indications by Combining the Furosemide Stress Test and Chemokine (C-C Motif) Ligand 14 in a Cohort of Postsurgical Patients. Crit Care Med. 2023 08 01; 51(8):1033-1042.