Kulandaivelu Vetrivel to Amyloid Precursor Protein Secretases
This is a "connection" page, showing publications Kulandaivelu Vetrivel has written about Amyloid Precursor Protein Secretases.
Connection Strength
1.751
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Loss of cleavage at ß'-site contributes to apparent increase in ß-amyloid peptide (Aß) secretion by ß-secretase (BACE1)-glycosylphosphatidylinositol (GPI) processing of amyloid precursor protein. J Biol Chem. 2011 Jul 22; 286(29):26166-77.
Score: 0.386
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Alzheimer disease Abeta production in the absence of S-palmitoylation-dependent targeting of BACE1 to lipid rafts. J Biol Chem. 2009 Feb 06; 284(6):3793-803.
Score: 0.325
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Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer's disease. Proc Natl Acad Sci U S A. 2017 11 07; 114(45):E9665-E9674.
Score: 0.150
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Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase. Mol Neurodegener. 2014 Jan 04; 9:1.
Score: 0.116
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A function for EHD family proteins in unidirectional retrograde dendritic transport of BACE1 and Alzheimer's disease Aß production. Cell Rep. 2013 Dec 26; 5(6):1552-63.
Score: 0.115
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Mutation analysis of the presenilin 1 N-terminal domain reveals a broad spectrum of gamma-secretase activity toward amyloid precursor protein and other substrates. J Biol Chem. 2010 Dec 03; 285(49):38042-52.
Score: 0.092
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Membrane rafts in Alzheimer's disease beta-amyloid production. Biochim Biophys Acta. 2010 Aug; 1801(8):860-7.
Score: 0.089
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S-palmitoylation of gamma-secretase subunits nicastrin and APH-1. J Biol Chem. 2009 Jan 16; 284(3):1373-84.
Score: 0.081
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Evidence that CD147 modulation of beta-amyloid (Abeta) levels is mediated by extracellular degradation of secreted Abeta. J Biol Chem. 2008 Jul 11; 283(28):19489-98.
Score: 0.078
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Cellular distribution of gamma-secretase subunit nicastrin in the developing and adult rat brains. Neurobiol Aging. 2008 May; 29(5):724-38.
Score: 0.071
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Amyloidogenic processing of beta-amyloid precursor protein in intracellular compartments. Neurology. 2006 Jan 24; 66(2 Suppl 1):S69-73.
Score: 0.067
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Spatial segregation of gamma-secretase and substrates in distinct membrane domains. J Biol Chem. 2005 Jul 08; 280(27):25892-900.
Score: 0.063
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Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes. J Biol Chem. 2004 Oct 22; 279(43):44945-54.
Score: 0.060
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Altered levels and distribution of amyloid precursor protein and its processing enzymes in Niemann-Pick type C1-deficient mouse brains. Glia. 2010 Aug 15; 58(11):1267-81.
Score: 0.023
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Mechanisms of disease: new therapeutic strategies for Alzheimer's disease--targeting APP processing in lipid rafts. Nat Clin Pract Neurol. 2007 Jul; 3(7):374-82.
Score: 0.018
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Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components. J Biol Chem. 2005 Apr 29; 280(17):17020-6.
Score: 0.016