Kenneth S. Polonsky to Apoptosis
This is a "connection" page, showing publications Kenneth S. Polonsky has written about Apoptosis.
Connection Strength
1.817
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BH3-only molecule Bim mediates ß-cell death in IRS2 deficiency. Diabetes. 2014 Oct; 63(10):3378-87.
Score: 0.304
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Loss of Nix in Pdx1-deficient mice prevents apoptotic and necrotic ß cell death and diabetes. J Clin Invest. 2010 Nov; 120(11):4031-9.
Score: 0.238
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Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome. Proc Natl Acad Sci U S A. 2006 Dec 19; 103(51):19575-80.
Score: 0.183
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Suppressed insulin signaling and increased apoptosis in CD38-null islets. Diabetes. 2006 Oct; 55(10):2737-46.
Score: 0.180
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RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets. J Biol Chem. 2004 Jun 04; 279(23):24794-802.
Score: 0.151
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Increased islet apoptosis in Pdx1+/- mice. J Clin Invest. 2003 Apr; 111(8):1147-60.
Score: 0.141
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Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion. Am J Physiol Endocrinol Metab. 2000 Feb; 278(2):E340-51.
Score: 0.114
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Apoptosis in insulin-secreting cells. Evidence for the role of intracellular Ca2+ stores and arachidonic acid metabolism. J Clin Invest. 1998 Apr 15; 101(8):1623-32.
Score: 0.100
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Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat. Diabetes. 1998 Mar; 47(3):358-64.
Score: 0.099
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Pancreatic ß-Cell Death due to Pdx-1 Deficiency Requires Multi-BH Domain Protein Bax but Not Bak. J Biol Chem. 2016 Jun 24; 291(26):13529-34.
Score: 0.088
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Role of BH3-only molecules Bim and Puma in ß-cell death in Pdx1 deficiency. Diabetes. 2014 Aug; 63(8):2744-50.
Score: 0.076
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Carboxypeptidase E mediates palmitate-induced beta-cell ER stress and apoptosis. Proc Natl Acad Sci U S A. 2008 Jun 17; 105(24):8452-7.
Score: 0.051
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Sustained expression of hepatocyte nuclear factor-6 leads to loss of pancreatic beta-cells by apoptosis. Exp Clin Endocrinol Diabetes. 2007 Nov; 115(10):654-61.
Score: 0.049
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Targeting cyclophilin D and the mitochondrial permeability transition enhances beta-cell survival and prevents diabetes in Pdx1 deficiency. Proc Natl Acad Sci U S A. 2010 Jun 01; 107(22):10214-9.
Score: 0.014
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Reduced expression of the insulin receptor in mouse insulinoma (MIN6) cells reveals multiple roles of insulin signaling in gene expression, proliferation, insulin content, and secretion. J Biol Chem. 2005 Feb 11; 280(6):4992-5003.
Score: 0.010
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Defective insulin secretion and increased susceptibility to experimental diabetes are induced by reduced Akt activity in pancreatic islet beta cells. J Clin Invest. 2004 Oct; 114(7):928-36.
Score: 0.010
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Visualizing superoxide production in normal and diabetic rat islets of Langerhans. J Biol Chem. 2003 Mar 14; 278(11):9796-801.
Score: 0.009