Eduardo Perozo to Ion Channel Gating
This is a "connection" page, showing publications Eduardo Perozo has written about Ion Channel Gating.
Connection Strength
8.802
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Mechanism of voltage sensing in Ca2+- and voltage-activated K+ (BK) channels. Proc Natl Acad Sci U S A. 2022 06 21; 119(25):e2204620119.
Score: 0.704
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Electromechanical coupling in the hyperpolarization-activated K+ channel KAT1. Nature. 2020 07; 583(7814):145-149.
Score: 0.610
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Dynamics transitions at the outer vestibule of the KcsA potassium channel during gating. Proc Natl Acad Sci U S A. 2014 Feb 04; 111(5):1831-6.
Score: 0.393
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Expression, purification, and reconstitution of the voltage-sensing domain from Ci-VSP. Biochemistry. 2012 Oct 16; 51(41):8132-42.
Score: 0.359
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Symmetry-constrained analysis of pulsed double electron-electron resonance (DEER) spectroscopy reveals the dynamic nature of the KcsA activation gate. J Am Chem Soc. 2012 Oct 03; 134(39):16360-9.
Score: 0.358
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Mechanism of activation gating in the full-length KcsA K+ channel. Proc Natl Acad Sci U S A. 2011 Jul 19; 108(29):11896-9.
Score: 0.330
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A multipoint hydrogen-bond network underlying KcsA C-type inactivation. Biophys J. 2011 May 18; 100(10):2387-93.
Score: 0.327
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Structural mechanism of C-type inactivation in K(+) channels. Nature. 2010 Jul 08; 466(7303):203-8.
Score: 0.308
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Design and characterization of a constitutively open KcsA. FEBS Lett. 2010 Mar 19; 584(6):1133-8.
Score: 0.299
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A molecular mechanism for proton-dependent gating in KcsA. FEBS Lett. 2010 Mar 19; 584(6):1126-32.
Score: 0.299
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Structural biology: A channel with a twist. Nature. 2009 Sep 03; 461(7260):47-9.
Score: 0.290
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Structural dynamics of an isolated voltage-sensor domain in a lipid bilayer. Structure. 2008 Mar; 16(3):398-409.
Score: 0.261
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How to gate an ion channel: lessons from MthK. Nat Struct Mol Biol. 2007 Mar; 14(3):180-2.
Score: 0.244
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Mechanism of voltage gating in the voltage-sensing phosphatase Ci-VSP. Proc Natl Acad Sci U S A. 2022 11; 119(44):e2206649119.
Score: 0.180
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Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gating. Nat Struct Biol. 2002 Sep; 9(9):696-703.
Score: 0.179
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Open channel structure of MscL and the gating mechanism of mechanosensitive channels. Nature. 2002 Aug 29; 418(6901):942-8.
Score: 0.178
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New structural perspectives on K(+) channel gating. Structure. 2002 Aug; 10(8):1027-9.
Score: 0.177
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Structure of the KcsA channel intracellular gate in the open state. Nat Struct Biol. 2001 Oct; 8(10):883-7.
Score: 0.168
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Computational study of non-conductive selectivity filter conformations and C-type inactivation in a voltage-dependent potassium channel. J Gen Physiol. 2021 09 06; 153(9).
Score: 0.166
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Molecular architecture of full-length KcsA: role of cytoplasmic domains in ion permeation and activation gating. J Gen Physiol. 2001 Feb; 117(2):165-80.
Score: 0.160
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Real time dynamics of Gating-Related conformational changes in CorA. Elife. 2019 11 27; 8.
Score: 0.147
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Structural rearrangements underlying K+-channel activation gating. Science. 1999 Jul 02; 285(5424):73-8.
Score: 0.143
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Shedding light on voltage-dependent gating. J Gen Physiol. 1998 Oct; 112(4):373-6.
Score: 0.136
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Three-dimensional architecture and gating mechanism of a K+ channel studied by EPR spectroscopy. Nat Struct Biol. 1998 Jun; 5(6):459-69.
Score: 0.133
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pH-dependent gating in the Streptomyces lividans K+ channel. Biochemistry. 1998 Mar 10; 37(10):3229-36.
Score: 0.131
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Never at rest: insights into the conformational dynamics of ion channels from cryo-electron microscopy. J Physiol. 2018 04 01; 596(7):1107-1119.
Score: 0.131
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Probing the Effects of Gating on the Ion Occupancy of the K+ Channel Selectivity Filter Using Two-Dimensional Infrared Spectroscopy. J Am Chem Soc. 2017 07 05; 139(26):8837-8845.
Score: 0.124
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Resting state of the human proton channel dimer in a lipid bilayer. Proc Natl Acad Sci U S A. 2015 Nov 03; 112(44):E5926-35.
Score: 0.111
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Conformational dynamics at the inner gate of KcsA during activation. Biochemistry. 2014 Apr 29; 53(16):2557-9.
Score: 0.100
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S4 mutations alter gating currents of Shaker K channels. Biophys J. 1994 Feb; 66(2 Pt 1):345-54.
Score: 0.099
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Gating currents from a nonconducting mutant reveal open-closed conformations in Shaker K+ channels. Neuron. 1993 Aug; 11(2):353-8.
Score: 0.095
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Recovery from slow inactivation in K+ channels is controlled by water molecules. Nature. 2013 Sep 05; 501(7465):121-4.
Score: 0.095
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Importance of lipid-pore loop interface for potassium channel structure and function. Proc Natl Acad Sci U S A. 2013 Aug 06; 110(32):13008-13.
Score: 0.095
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An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations. J Gen Physiol. 2012 Dec; 140(6):587-94.
Score: 0.091
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Gating currents in Shaker K+ channels. Implications for activation and inactivation models. Biophys J. 1992 Apr; 62(1):160-8; discussion 169-71.
Score: 0.087
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Molecular coupling in the human ether-a-go-go-related gene-1 (hERG1) K+ channel inactivation pathway. J Biol Chem. 2011 Nov 11; 286(45):39091-9.
Score: 0.083
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On the structural basis of modal gating behavior in K(+) channels. Nat Struct Mol Biol. 2011 Jan; 18(1):67-74.
Score: 0.079
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Phosphorylation affects voltage gating of the delayed rectifier K+ channel by electrostatic interactions. Neuron. 1990 Nov; 5(5):685-90.
Score: 0.079
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Structural basis for the coupling between activation and inactivation gates in K(+) channels. Nature. 2010 Jul 08; 466(7303):272-5.
Score: 0.077
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A structural mechanism for MscS gating in lipid bilayers. Science. 2008 Aug 29; 321(5893):1210-4.
Score: 0.068
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A quantitative description of KcsA gating I: macroscopic currents. J Gen Physiol. 2007 Nov; 130(5):465-78.
Score: 0.064
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A quantitative description of KcsA gating II: single-channel currents. J Gen Physiol. 2007 Nov; 130(5):479-96.
Score: 0.064
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Molecular driving forces determining potassium channel slow inactivation. Nat Struct Mol Biol. 2007 Nov; 14(11):1062-9.
Score: 0.064
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Ion conduction through MscS as determined by electrophysiology and simulation. Biophys J. 2007 Feb 01; 92(3):886-902.
Score: 0.060
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Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction. J Gen Physiol. 2006 Nov; 128(5):569-81.
Score: 0.059
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Voltage-dependent gating at the KcsA selectivity filter. Nat Struct Mol Biol. 2006 Apr; 13(4):319-22.
Score: 0.057
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Structural biology. Force and voltage sensors in one structure. Science. 2002 Nov 22; 298(5598):1562-3.
Score: 0.045
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EPR approaches to ion channel structure and function. Novartis Found Symp. 2002; 245:146-58; discussion 158-64, 165-8.
Score: 0.043
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Direct activation of the proton channel by albumin leads to human sperm capacitation and sustained release of inflammatory mediators by neutrophils. Nat Commun. 2021 06 22; 12(1):3855.
Score: 0.041
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The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels. Nat Commun. 2016 06 22; 7:11984.
Score: 0.029
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Multi-ion free energy landscapes underscore the microscopic mechanism of ion selectivity in the KcsA channel. Biochim Biophys Acta. 2016 Jul; 1858(7 Pt B):1722-32.
Score: 0.028
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Gating of Shaker K+ channels: II. The components of gating currents and a model of channel activation. Biophys J. 1994 Apr; 66(4):1011-21.
Score: 0.025
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Gating of Shaker K+ channels: I. Ionic and gating currents. Biophys J. 1994 Apr; 66(4):996-1010.
Score: 0.025
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Voltage activation of reconstituted sodium channels: use of bacteriorhodopsin as a light-driven current source. Biochemistry. 1993 Oct 05; 32(39):10471-8.
Score: 0.024
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Thermodynamic coupling between activation and inactivation gating in potassium channels revealed by free energy molecular dynamics simulations. J Gen Physiol. 2011 Dec; 138(6):571-80.
Score: 0.021
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Molecular basis of gating charge immobilization in Shaker potassium channels. Science. 1991 Nov 01; 254(5032):679-83.
Score: 0.021
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The activated state of a sodium channel voltage sensor in a membrane environment. Proc Natl Acad Sci U S A. 2010 Mar 23; 107(12):5435-40.
Score: 0.019
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Molecular determinants of gating at the potassium-channel selectivity filter. Nat Struct Mol Biol. 2006 Apr; 13(4):311-8.
Score: 0.014
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Chemical modification of squid axon K+ channel -SH groups with the organic mercurial compound p-hydroxymercuriphenylsulfonic acid (PHMPS). Pflugers Arch. 1994 Oct; 428(3-4):315-22.
Score: 0.006