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Connection

Eduardo Perozo to Ion Channel Gating

This is a "connection" page, showing publications Eduardo Perozo has written about Ion Channel Gating.
Connection Strength

8.285
  1. Mechanism of voltage sensing in Ca2+- and voltage-activated K+ (BK) channels. Proc Natl Acad Sci U S A. 2022 06 21; 119(25):e2204620119.
    View in: PubMed
    Score: 0.659
  2. Electromechanical coupling in the hyperpolarization-activated K+ channel KAT1. Nature. 2020 07; 583(7814):145-149.
    View in: PubMed
    Score: 0.571
  3. Dynamics transitions at the outer vestibule of the KcsA potassium channel during gating. Proc Natl Acad Sci U S A. 2014 Feb 04; 111(5):1831-6.
    View in: PubMed
    Score: 0.368
  4. Expression, purification, and reconstitution of the voltage-sensing domain from Ci-VSP. Biochemistry. 2012 Oct 16; 51(41):8132-42.
    View in: PubMed
    Score: 0.336
  5. Symmetry-constrained analysis of pulsed double electron-electron resonance (DEER) spectroscopy reveals the dynamic nature of the KcsA activation gate. J Am Chem Soc. 2012 Oct 03; 134(39):16360-9.
    View in: PubMed
    Score: 0.335
  6. Mechanism of activation gating in the full-length KcsA K+ channel. Proc Natl Acad Sci U S A. 2011 Jul 19; 108(29):11896-9.
    View in: PubMed
    Score: 0.308
  7. A multipoint hydrogen-bond network underlying KcsA C-type inactivation. Biophys J. 2011 May 18; 100(10):2387-93.
    View in: PubMed
    Score: 0.306
  8. Structural mechanism of C-type inactivation in K(+) channels. Nature. 2010 Jul 08; 466(7303):203-8.
    View in: PubMed
    Score: 0.288
  9. Design and characterization of a constitutively open KcsA. FEBS Lett. 2010 Mar 19; 584(6):1133-8.
    View in: PubMed
    Score: 0.280
  10. A molecular mechanism for proton-dependent gating in KcsA. FEBS Lett. 2010 Mar 19; 584(6):1126-32.
    View in: PubMed
    Score: 0.280
  11. Structural biology: A channel with a twist. Nature. 2009 Sep 03; 461(7260):47-9.
    View in: PubMed
    Score: 0.272
  12. Structural dynamics of an isolated voltage-sensor domain in a lipid bilayer. Structure. 2008 Mar; 16(3):398-409.
    View in: PubMed
    Score: 0.245
  13. How to gate an ion channel: lessons from MthK. Nat Struct Mol Biol. 2007 Mar; 14(3):180-2.
    View in: PubMed
    Score: 0.228
  14. Mechanism of voltage gating in the voltage-sensing phosphatase Ci-VSP. Proc Natl Acad Sci U S A. 2022 11; 119(44):e2206649119.
    View in: PubMed
    Score: 0.169
  15. Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gating. Nat Struct Biol. 2002 Sep; 9(9):696-703.
    View in: PubMed
    Score: 0.167
  16. Open channel structure of MscL and the gating mechanism of mechanosensitive channels. Nature. 2002 Aug 29; 418(6901):942-8.
    View in: PubMed
    Score: 0.167
  17. New structural perspectives on K(+) channel gating. Structure. 2002 Aug; 10(8):1027-9.
    View in: PubMed
    Score: 0.166
  18. Structure of the KcsA channel intracellular gate in the open state. Nat Struct Biol. 2001 Oct; 8(10):883-7.
    View in: PubMed
    Score: 0.157
  19. Computational study of non-conductive selectivity filter conformations and C-type inactivation in a voltage-dependent potassium channel. J Gen Physiol. 2021 09 06; 153(9).
    View in: PubMed
    Score: 0.155
  20. Molecular architecture of full-length KcsA: role of cytoplasmic domains in ion permeation and activation gating. J Gen Physiol. 2001 Feb; 117(2):165-80.
    View in: PubMed
    Score: 0.150
  21. Real time dynamics of Gating-Related conformational changes in CorA. Elife. 2019 11 27; 8.
    View in: PubMed
    Score: 0.138
  22. Structural rearrangements underlying K+-channel activation gating. Science. 1999 Jul 02; 285(5424):73-8.
    View in: PubMed
    Score: 0.134
  23. Shedding light on voltage-dependent gating. J Gen Physiol. 1998 Oct; 112(4):373-6.
    View in: PubMed
    Score: 0.127
  24. Three-dimensional architecture and gating mechanism of a K+ channel studied by EPR spectroscopy. Nat Struct Biol. 1998 Jun; 5(6):459-69.
    View in: PubMed
    Score: 0.124
  25. pH-dependent gating in the Streptomyces lividans K+ channel. Biochemistry. 1998 Mar 10; 37(10):3229-36.
    View in: PubMed
    Score: 0.122
  26. Never at rest: insights into the conformational dynamics of ion channels from cryo-electron microscopy. J Physiol. 2018 04 01; 596(7):1107-1119.
    View in: PubMed
    Score: 0.122
  27. Probing the Effects of Gating on the Ion Occupancy of the K+ Channel Selectivity Filter Using Two-Dimensional Infrared Spectroscopy. J Am Chem Soc. 2017 07 05; 139(26):8837-8845.
    View in: PubMed
    Score: 0.116
  28. Resting state of the human proton channel dimer in a lipid bilayer. Proc Natl Acad Sci U S A. 2015 Nov 03; 112(44):E5926-35.
    View in: PubMed
    Score: 0.104
  29. Conformational dynamics at the inner gate of KcsA during activation. Biochemistry. 2014 Apr 29; 53(16):2557-9.
    View in: PubMed
    Score: 0.094
  30. S4 mutations alter gating currents of Shaker K channels. Biophys J. 1994 Feb; 66(2 Pt 1):345-54.
    View in: PubMed
    Score: 0.092
  31. Gating currents from a nonconducting mutant reveal open-closed conformations in Shaker K+ channels. Neuron. 1993 Aug; 11(2):353-8.
    View in: PubMed
    Score: 0.089
  32. Recovery from slow inactivation in K+ channels is controlled by water molecules. Nature. 2013 Sep 05; 501(7465):121-4.
    View in: PubMed
    Score: 0.089
  33. Importance of lipid-pore loop interface for potassium channel structure and function. Proc Natl Acad Sci U S A. 2013 Aug 06; 110(32):13008-13.
    View in: PubMed
    Score: 0.089
  34. An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations. J Gen Physiol. 2012 Dec; 140(6):587-94.
    View in: PubMed
    Score: 0.085
  35. Gating currents in Shaker K+ channels. Implications for activation and inactivation models. Biophys J. 1992 Apr; 62(1):160-8; discussion 169-71.
    View in: PubMed
    Score: 0.081
  36. Molecular coupling in the human ether-a-go-go-related gene-1 (hERG1) K+ channel inactivation pathway. J Biol Chem. 2011 Nov 11; 286(45):39091-9.
    View in: PubMed
    Score: 0.078
  37. On the structural basis of modal gating behavior in K(+) channels. Nat Struct Mol Biol. 2011 Jan; 18(1):67-74.
    View in: PubMed
    Score: 0.074
  38. Phosphorylation affects voltage gating of the delayed rectifier K+ channel by electrostatic interactions. Neuron. 1990 Nov; 5(5):685-90.
    View in: PubMed
    Score: 0.074
  39. Structural basis for the coupling between activation and inactivation gates in K(+) channels. Nature. 2010 Jul 08; 466(7303):272-5.
    View in: PubMed
    Score: 0.072
  40. A structural mechanism for MscS gating in lipid bilayers. Science. 2008 Aug 29; 321(5893):1210-4.
    View in: PubMed
    Score: 0.063
  41. A quantitative description of KcsA gating I: macroscopic currents. J Gen Physiol. 2007 Nov; 130(5):465-78.
    View in: PubMed
    Score: 0.060
  42. A quantitative description of KcsA gating II: single-channel currents. J Gen Physiol. 2007 Nov; 130(5):479-96.
    View in: PubMed
    Score: 0.060
  43. Molecular driving forces determining potassium channel slow inactivation. Nat Struct Mol Biol. 2007 Nov; 14(11):1062-9.
    View in: PubMed
    Score: 0.059
  44. Ion conduction through MscS as determined by electrophysiology and simulation. Biophys J. 2007 Feb 01; 92(3):886-902.
    View in: PubMed
    Score: 0.056
  45. Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction. J Gen Physiol. 2006 Nov; 128(5):569-81.
    View in: PubMed
    Score: 0.056
  46. Voltage-dependent gating at the KcsA selectivity filter. Nat Struct Mol Biol. 2006 Apr; 13(4):319-22.
    View in: PubMed
    Score: 0.053
  47. Potassium dependent structural changes in the selectivity filter of HERG potassium channels. Nat Commun. 2024 Aug 29; 15(1):7470.
    View in: PubMed
    Score: 0.048
  48. Structural biology. Force and voltage sensors in one structure. Science. 2002 Nov 22; 298(5598):1562-3.
    View in: PubMed
    Score: 0.042
  49. EPR approaches to ion channel structure and function. Novartis Found Symp. 2002; 245:146-58; discussion 158-64, 165-8.
    View in: PubMed
    Score: 0.040
  50. Direct activation of the proton channel by albumin leads to human sperm capacitation and sustained release of inflammatory mediators by neutrophils. Nat Commun. 2021 06 22; 12(1):3855.
    View in: PubMed
    Score: 0.038
  51. The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels. Nat Commun. 2016 06 22; 7:11984.
    View in: PubMed
    Score: 0.027
  52. Multi-ion free energy landscapes underscore the microscopic mechanism of ion selectivity in the KcsA channel. Biochim Biophys Acta. 2016 Jul; 1858(7 Pt B):1722-32.
    View in: PubMed
    Score: 0.027
  53. Gating of Shaker K+ channels: II. The components of gating currents and a model of channel activation. Biophys J. 1994 Apr; 66(4):1011-21.
    View in: PubMed
    Score: 0.023
  54. Gating of Shaker K+ channels: I. Ionic and gating currents. Biophys J. 1994 Apr; 66(4):996-1010.
    View in: PubMed
    Score: 0.023
  55. Voltage activation of reconstituted sodium channels: use of bacteriorhodopsin as a light-driven current source. Biochemistry. 1993 Oct 05; 32(39):10471-8.
    View in: PubMed
    Score: 0.023
  56. Thermodynamic coupling between activation and inactivation gating in potassium channels revealed by free energy molecular dynamics simulations. J Gen Physiol. 2011 Dec; 138(6):571-80.
    View in: PubMed
    Score: 0.020
  57. Molecular basis of gating charge immobilization in Shaker potassium channels. Science. 1991 Nov 01; 254(5032):679-83.
    View in: PubMed
    Score: 0.020
  58. The activated state of a sodium channel voltage sensor in a membrane environment. Proc Natl Acad Sci U S A. 2010 Mar 23; 107(12):5435-40.
    View in: PubMed
    Score: 0.018
  59. Molecular determinants of gating at the potassium-channel selectivity filter. Nat Struct Mol Biol. 2006 Apr; 13(4):311-8.
    View in: PubMed
    Score: 0.013
  60. Chemical modification of squid axon K+ channel -SH groups with the organic mercurial compound p-hydroxymercuriphenylsulfonic acid (PHMPS). Pflugers Arch. 1994 Oct; 428(3-4):315-22.
    View in: PubMed
    Score: 0.006
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.