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Connection

Ralph Weichselbaum to Enzyme Activation

This is a "connection" page, showing publications Ralph Weichselbaum has written about Enzyme Activation.
Connection Strength

0.987
  1. Small molecule derived from a natural product that mitigates radiation injury. Proc Natl Acad Sci U S A. 2013 Nov 12; 110(46):18355-6.
    View in: PubMed
    Score: 0.363
  2. A downside to apoptosis in cancer therapy? Nat Med. 2011 Jul 07; 17(7):780-2.
    View in: PubMed
    Score: 0.077
  3. Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1. J Virol. 2006 Feb; 80(3):1110-20.
    View in: PubMed
    Score: 0.053
  4. Ionizing radiation activates late herpes simplex virus 1 promoters via the p38 pathway in tumors treated with oncolytic viruses. Cancer Res. 2005 Oct 15; 65(20):9479-84.
    View in: PubMed
    Score: 0.052
  5. Down-regulation of ceramide production abrogates ionizing radiation-induced cytochrome c release and apoptosis. Mol Pharmacol. 2000 Apr; 57(4):792-6.
    View in: PubMed
    Score: 0.035
  6. Decreasing the apoptotic threshold of tumor cells through protein kinase C inhibition and sphingomyelinase activation increases tumor killing by ionizing radiation. Cancer Res. 1997 Oct 01; 57(19):4340-7.
    View in: PubMed
    Score: 0.030
  7. Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells. EMBO J. 1995 Dec 15; 14(24):6148-56.
    View in: PubMed
    Score: 0.026
  8. Activation of Src-like p56/p53lyn tyrosine kinase by ionizing radiation. J Biol Chem. 1994 Aug 12; 269(32):20739-43.
    View in: PubMed
    Score: 0.024
  9. The role of intracellular calcium in the cellular response to ionizing radiation. Radiat Res. 1994 Jun; 138(3):392-400.
    View in: PubMed
    Score: 0.024
  10. Membrane-derived second messenger regulates x-ray-mediated tumor necrosis factor alpha gene induction. Proc Natl Acad Sci U S A. 1994 May 24; 91(11):4897-901.
    View in: PubMed
    Score: 0.024
  11. Radiation signaling mediated by Jun activation following dissociation from a cell type-specific repressor. J Biol Chem. 1993 Mar 05; 268(7):4903-7.
    View in: PubMed
    Score: 0.022
  12. The isoquinoline sulfonamide H7 attenuates radiation-mediated protein kinase C activation and delays the onset of x-ray-induced G2 arrest. Int J Radiat Oncol Biol Phys. 1992; 24(4):687-92.
    View in: PubMed
    Score: 0.020
  13. Mechanisms of X-ray-mediated protooncogene c-jun expression in radiation-induced human sarcoma cell lines. Int J Radiat Oncol Biol Phys. 1991 Nov; 21(6):1677-81.
    View in: PubMed
    Score: 0.020
  14. SOD2-mediated adaptive responses induced by low-dose ionizing radiation via TNF signaling and amifostine. Free Radic Biol Med. 2011 Nov 15; 51(10):1918-25.
    View in: PubMed
    Score: 0.020
  15. Tumor necrosis factor gene expression is mediated by protein kinase C following activation by ionizing radiation. Cancer Res. 1991 Sep 01; 51(17):4565-9.
    View in: PubMed
    Score: 0.020
  16. Herpes simplex virus 1 activates cdc2 to recruit topoisomerase II alpha for post-DNA synthesis expression of late genes. Proc Natl Acad Sci U S A. 2003 Apr 15; 100(8):4825-30.
    View in: PubMed
    Score: 0.011
  17. Interaction of hematopoietic progenitor kinase 1 and c-Abl tyrosine kinase in response to genotoxic stress. J Biol Chem. 2001 May 25; 276(21):18130-8.
    View in: PubMed
    Score: 0.009
  18. The role of cdc2 in the expression of herpes simplex virus genes. Proc Natl Acad Sci U S A. 2000 Sep 26; 97(20):10996-1001.
    View in: PubMed
    Score: 0.009
  19. Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90. EMBO J. 2000 Aug 15; 19(16):4310-22.
    View in: PubMed
    Score: 0.009
  20. Role for Lyn tyrosine kinase as a regulator of stress-activated protein kinase activity in response to DNA damage. Mol Cell Biol. 2000 Aug; 20(15):5370-80.
    View in: PubMed
    Score: 0.009
  21. Activation of MEK kinase 1 by the c-Abl protein tyrosine kinase in response to DNA damage. Mol Cell Biol. 2000 Jul; 20(14):4979-89.
    View in: PubMed
    Score: 0.009
  22. Activation of the cytoplasmic c-Abl tyrosine kinase by reactive oxygen species. J Biol Chem. 2000 Jun 09; 275(23):17237-40.
    View in: PubMed
    Score: 0.009
  23. Hsp27 functions as a negative regulator of cytochrome c-dependent activation of procaspase-3. Oncogene. 2000 Apr 13; 19(16):1975-81.
    View in: PubMed
    Score: 0.009
  24. The disappearance of cyclins A and B and the increase in activity of the G(2)/M-phase cellular kinase cdc2 in herpes simplex virus 1-infected cells require expression of the alpha22/U(S)1.5 and U(L)13 viral genes. J Virol. 2000 Jan; 74(1):8-15.
    View in: PubMed
    Score: 0.009
  25. Determination of cell fate by c-Abl activation in the response to DNA damage. Oncogene. 1998 Dec 24; 17(25):3309-18.
    View in: PubMed
    Score: 0.008
  26. Activation of protein kinase C delta by the c-Abl tyrosine kinase in response to ionizing radiation. Oncogene. 1998 Apr 02; 16(13):1643-8.
    View in: PubMed
    Score: 0.008
  27. Functional role for the c-Abl protein tyrosine kinase in the cellular response to genotoxic stress. Biochim Biophys Acta. 1997 Oct 24; 1333(2):O1-7.
    View in: PubMed
    Score: 0.007
  28. Functional interaction between DNA-PK and c-Abl in response to DNA damage. Nature. 1997 Apr 17; 386(6626):732-5.
    View in: PubMed
    Score: 0.007
  29. Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase. Proc Natl Acad Sci U S A. 1997 Feb 18; 94(4):1437-40.
    View in: PubMed
    Score: 0.007
  30. Activation of p38 mitogen-activated protein kinase by c-Abl-dependent and -independent mechanisms. J Biol Chem. 1996 Sep 27; 271(39):23775-9.
    View in: PubMed
    Score: 0.007
  31. Nuclear signaling induced by ionizing radiation involves colocalization of the activated p56/p53lyn tyrosine kinase with p34cdc2. Cancer Res. 1996 Aug 15; 56(16):3617-21.
    View in: PubMed
    Score: 0.007
  32. Cross-talk between ceramide and PKC activity in the control of apoptosis in WEHI-231. Adv Exp Med Biol. 1996; 406:39-55.
    View in: PubMed
    Score: 0.007
  33. Blockage of the early events of mitogenic signaling by interferon-gamma in macrophages in response to colony-stimulating factor-1. Blood. 1995 Oct 01; 86(7):2774-88.
    View in: PubMed
    Score: 0.006
  34. Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents. Nature. 1995 Aug 31; 376(6543):785-8.
    View in: PubMed
    Score: 0.006
  35. Ionizing radiation stimulates a Grb2-mediated association of the stress-activated protein kinase with phosphatidylinositol 3-kinase. J Biol Chem. 1995 Aug 11; 270(32):18871-4.
    View in: PubMed
    Score: 0.006
  36. Defective induction of stress-activated protein kinase activity in ataxia-telangiectasia cells exposed to ionizing radiation. Cancer Res. 1995 Aug 01; 55(15):3242-5.
    View in: PubMed
    Score: 0.006
  37. p56/p53lyn tyrosine kinase activation in mammalian cells treated with mitomycin C. Oncogene. 1994 Oct; 9(10):3005-11.
    View in: PubMed
    Score: 0.006
  38. Activation of the pp90rsk and mitogen-activated serine/threonine protein kinases by ionizing radiation. Proc Natl Acad Sci U S A. 1994 Jun 07; 91(12):5416-20.
    View in: PubMed
    Score: 0.006
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.