Ralph Weichselbaum to Apoptosis
This is a "connection" page, showing publications Ralph Weichselbaum has written about Apoptosis.
Connection Strength
2.096
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A downside to apoptosis in cancer therapy? Nat Med. 2011 Jul 07; 17(7):780-2.
Score: 0.218
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Diverse TNFalpha-induced death pathways are enhanced by inhibition of NF-kappaB. Int J Oncol. 2007 Dec; 31(6):1519-28.
Score: 0.169
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Endothelial cells co-cultured with wild-type and dominant/negative p53-transfected glioblastoma cells exhibit differential sensitivity to radiation-induced apoptosis. Int J Cancer. 2004 Mar 20; 109(2):214-9.
Score: 0.131
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Down-regulation of ceramide production abrogates ionizing radiation-induced cytochrome c release and apoptosis. Mol Pharmacol. 2000 Apr; 57(4):792-6.
Score: 0.100
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Modulation of apoptotic response of a radiation-resistant human carcinoma by Pseudomonas exotoxin-chimeric protein. Cancer Res. 1998 Aug 01; 58(15):3215-20.
Score: 0.089
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Decreasing the apoptotic threshold of tumor cells through protein kinase C inhibition and sphingomyelinase activation increases tumor killing by ionizing radiation. Cancer Res. 1997 Oct 01; 57(19):4340-7.
Score: 0.084
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Loss of ceramide production confers resistance to radiation-induced apoptosis. Cancer Res. 1997 Apr 01; 57(7):1270-5.
Score: 0.081
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Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells. EMBO J. 1995 Dec 15; 14(24):6148-56.
Score: 0.074
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Suppression of Bcl-2 messenger RNA production may mediate apoptosis after ionizing radiation, tumor necrosis factor alpha, and ceramide. Cancer Res. 1995 Mar 01; 55(5):991-4.
Score: 0.070
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A survivin-associated adaptive response in radiation therapy. Cancer Res. 2013 Jul 15; 73(14):4418-28.
Score: 0.062
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STAT1 pathway mediates amplification of metastatic potential and resistance to therapy. PLoS One. 2009 Jun 08; 4(6):e5821.
Score: 0.047
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Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling. Int J Radiat Biol. 2009 May; 85(5):421-31.
Score: 0.047
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Concomitant proliferation and caspase-3 mediated apoptosis in response to low shear stress and balloon injury. J Surg Res. 2010 Jun 01; 161(1):146-55.
Score: 0.045
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Translational strategies exploiting TNF-alpha that sensitize tumors to radiation therapy. Cancer Gene Ther. 2009 Apr; 16(4):373-81.
Score: 0.045
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Attenuated herpes simplex virus 1 blocks arterial apoptosis and intimal hyperplasia induced by balloon angioplasty and reduced blood flow. Proc Natl Acad Sci U S A. 2007 Jul 24; 104(30):12474-8.
Score: 0.041
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Cyclopamine increases the cytotoxic effects of paclitaxel and radiation but not cisplatin and gemcitabine in Hedgehog expressing pancreatic cancer cells. Cancer Chemother Pharmacol. 2006 Dec; 58(6):765-70.
Score: 0.038
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c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage. J Biol Chem. 2005 Mar 25; 280(12):11147-51.
Score: 0.035
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Interaction of amifostine and ionizing radiation on transcriptional patterns of apoptotic genes expressed in human microvascular endothelial cells (HMEC). Int J Radiat Oncol Biol Phys. 2004 Oct 01; 60(2):553-63.
Score: 0.034
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Transcriptional targeting of adenovirally delivered tumor necrosis factor alpha by temozolomide in experimental glioblastoma. Cancer Res. 2004 Sep 15; 64(18):6381-4.
Score: 0.034
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Glioblastoma cells block radiation-induced programmed cell death of endothelial cells. FEBS Lett. 2004 May 07; 565(1-3):167-70.
Score: 0.033
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Immunogenic Bifunctional Nanoparticle Suppresses Programmed Cell Death-Ligand 1 in Cancer and Dendritic Cells to Enhance Adaptive Immunity and Chemo-Immunotherapy. ACS Nano. 2024 02 13; 18(6):5152-5166.
Score: 0.032
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Gene therapy: the challenges of translating laboratory research into clinical practice. J Clin Oncol. 2003 Jun 15; 21(12):2230-1.
Score: 0.031
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Vascular endothelial growth factor enhances endothelial cell survival and tumor radioresistance. Cancer J. 2002 Jan-Feb; 8(1):47-54.
Score: 0.028
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Antitumor interaction of short-course endostatin and ionizing radiation. Cancer J. 2000 Sep-Oct; 6(5):287-93.
Score: 0.026
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In vitro and in vivo activity of protein kinase C inhibitor chelerythrine chloride induces tumor cell toxicity and growth delay in vivo. Clin Cancer Res. 2000 Feb; 6(2):737-42.
Score: 0.025
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Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage. J Biol Chem. 2000 Jan 07; 275(1):322-7.
Score: 0.025
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Function for p300 and not CBP in the apoptotic response to DNA damage. Oncogene. 1999 Oct 07; 18(41):5714-7.
Score: 0.024
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p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage. Nature. 1999 Jun 24; 399(6738):814-7.
Score: 0.024
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Role for caspase-mediated cleavage of Rad51 in induction of apoptosis by DNA damage. Mol Cell Biol. 1999 Apr; 19(4):2986-97.
Score: 0.023
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Combined effects of angiostatin and ionizing radiation in antitumour therapy. Nature. 1998 Jul 16; 394(6690):287-91.
Score: 0.022
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Nanoscale metal-organic frameworks enhance radiotherapy to potentiate checkpoint blockade immunotherapy. Nat Commun. 2018 06 15; 9(1):2351.
Score: 0.022
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JAK2 Inhibitor SAR302503 Abrogates PD-L1 Expression and Targets Therapy-Resistant Non-small Cell Lung Cancers. Mol Cancer Ther. 2018 04; 17(4):732-739.
Score: 0.022
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Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis. Proc Natl Acad Sci U S A. 1997 Jun 24; 94(13):6939-42.
Score: 0.021
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Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase. Proc Natl Acad Sci U S A. 1997 Feb 18; 94(4):1437-40.
Score: 0.020
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p53 expression induces apoptosis in hippocampal pyramidal neuron cultures. J Neurosci. 1997 Feb 15; 17(4):1397-405.
Score: 0.020
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Activation of a CrmA-insensitive, p35-sensitive pathway in ionizing radiation-induced apoptosis. J Biol Chem. 1997 Jan 17; 272(3):1965-9.
Score: 0.020
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Photodynamic Therapy Mediated by Nontoxic Core-Shell Nanoparticles Synergizes with Immune Checkpoint Blockade To Elicit Antitumor Immunity and Antimetastatic Effect on Breast Cancer. J Am Chem Soc. 2016 12 28; 138(51):16686-16695.
Score: 0.020
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Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy. Nat Commun. 2016 08 17; 7:12499.
Score: 0.019
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Protein kinase C inhibition induces apoptosis and ceramide production through activation of a neutral sphingomyelinase. Cancer Res. 1996 Jun 15; 56(12):2711-4.
Score: 0.019
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Cross-talk between ceramide and PKC activity in the control of apoptosis in WEHI-231. Adv Exp Med Biol. 1996; 406:39-55.
Score: 0.019
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Spatial and temporal control of gene therapy using ionizing radiation. Nat Med. 1995 Aug; 1(8):786-91.
Score: 0.018
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Loss of Nfkb1 leads to early onset aging. Aging (Albany NY). 2014 Nov; 6(11):931-43.
Score: 0.017
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RIG-I-like receptor LGP2 protects tumor cells from ionizing radiation. Proc Natl Acad Sci U S A. 2014 Jan 28; 111(4):E484-91.
Score: 0.016
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Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice. J Clin Invest. 2014 Feb; 124(2):687-95.
Score: 0.016
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Adenoviral transduction of human acid sphingomyelinase into neo-angiogenic endothelium radiosensitizes tumor cure. PLoS One. 2013; 8(8):e69025.
Score: 0.016
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Mg ATP and antioxidants augment the radioprotective effect of surfactant copolymers. Health Phys. 2011 Dec; 101(6):731-8.
Score: 0.014
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Oral PEG 15-20 protects the intestine against radiation: role of lipid rafts. Am J Physiol Gastrointest Liver Physiol. 2009 Dec; 297(6):G1041-52.
Score: 0.012
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Lyn tyrosine kinase inhibits nuclear export of the p53 tumor suppressor. Cancer Biol Ther. 2002 Nov-Dec; 1(6):703-8.
Score: 0.007
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The novel isocoumarin 2-(8-hydroxy-6-methoxy-1-oxo-1H-2-benzopyran-3-yl) propionic acid (NM-3) induces lethality of human carcinoma cells by generation of reactive oxygen species. Mol Cancer Ther. 2001 Nov; 1(1):43-8.
Score: 0.007
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Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90. EMBO J. 2000 Aug 15; 19(16):4310-22.
Score: 0.006
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Role for Lyn tyrosine kinase as a regulator of stress-activated protein kinase activity in response to DNA damage. Mol Cell Biol. 2000 Aug; 20(15):5370-80.
Score: 0.006
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Gene therapy enhances the antiproliferative effect of radiation in intimal hyperplasia. J Surg Res. 2000 Apr; 89(2):155-62.
Score: 0.006
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Determination of cell fate by c-Abl activation in the response to DNA damage. Oncogene. 1998 Dec 24; 17(25):3309-18.
Score: 0.006
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Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosis. Mol Cell Biol. 1998 Nov; 18(11):6719-28.
Score: 0.006
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Functional role for the c-Abl protein tyrosine kinase in the cellular response to genotoxic stress. Biochim Biophys Acta. 1997 Oct 24; 1333(2):O1-7.
Score: 0.005