Ralph Weichselbaum to Signal Transduction
This is a "connection" page, showing publications Ralph Weichselbaum has written about Signal Transduction.
Connection Strength
2.080
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IFN signaling at the nexus of the radiotherapy response in malignant peripheral nerve sheath tumors. J Clin Invest. 2026 Mar 02; 136(5).
Score: 0.433
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Molecular pathways: interferon/stat1 pathway: role in the tumor resistance to genotoxic stress and aggressive growth. Clin Cancer Res. 2012 Jun 01; 18(11):3015-21.
Score: 0.167
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Amphiregulin as a Mediator of Radiation-Induced Systemic Effects in Metastatic Cancer: Balancing Local Control with Distant Progression. Clin Cancer Res. 2025 Dec 01; 31(23):4899-4902.
Score: 0.106
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The dark side of radiotherapy. Cancer Cell. 2025 Aug 11; 43(8):1385-1389.
Score: 0.103
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YTHDF2 inhibition potentiates radiotherapy antitumor efficacy. Cancer Cell. 2023 07 10; 41(7):1294-1308.e8.
Score: 0.089
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Intratumoral accumulation of gut microbiota facilitates CD47-based immunotherapy via STING signaling. J Exp Med. 2020 05 04; 217(5).
Score: 0.072
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DDX39B interacts with the pattern recognition receptor pathway to inhibit NF-?B and sensitize to alkylating chemotherapy. BMC Biol. 2020 03 24; 18(1):32.
Score: 0.072
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STING (or SRC) Like an ICB: Priming the Immune Response in Pancreatic Cancer. Cancer Res. 2019 08 01; 79(15):3815-3817.
Score: 0.069
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Oncogenic CXCL10 signalling drives metastasis development and poor clinical outcome. Br J Cancer. 2015 Jul 14; 113(2):327-35.
Score: 0.051
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MUC1-C activates the TAK1 inflammatory pathway in colon cancer. Oncogene. 2015 Oct 01; 34(40):5187-97.
Score: 0.050
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STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors. Immunity. 2014 Nov 20; 41(5):843-52.
Score: 0.049
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Radiation signaling mediated by Jun activation following dissociation from a cell type-specific repressor. J Biol Chem. 1993 Mar 05; 268(7):4903-7.
Score: 0.044
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A manganese superoxide dismutase (SOD2)-mediated adaptive response. Radiat Res. 2013 Feb; 179(2):115-24.
Score: 0.043
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Modulating vascular intimal hyperplasia using HSV-1 mutant requires activated MEK. Gene Ther. 2013 Feb; 20(2):215-24.
Score: 0.041
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Expression signature of IFN/STAT1 signaling genes predicts poor survival outcome in glioblastoma multiforme in a subtype-specific manner. PLoS One. 2012; 7(1):e29653.
Score: 0.041
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Tumor necrosis factor gene expression is mediated by protein kinase C following activation by ionizing radiation. Cancer Res. 1991 Sep 01; 51(17):4565-9.
Score: 0.040
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Protein kinase C mediates x-ray inducibility of nuclear signal transducers EGR1 and JUN. Proc Natl Acad Sci U S A. 1991 Mar 15; 88(6):2156-60.
Score: 0.038
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Efficacy of the multi-kinase inhibitor enzastaurin is dependent on cellular signaling context. Mol Cancer Ther. 2010 Oct; 9(10):2814-24.
Score: 0.037
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Blockade of tumor necrosis factor alpha signaling in tumor-associated macrophages as a radiosensitizing strategy. Cancer Res. 2010 Feb 15; 70(4):1534-43.
Score: 0.036
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Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer. Oncogene. 2010 Feb 11; 29(6):920-9.
Score: 0.035
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STAT1 pathway mediates amplification of metastatic potential and resistance to therapy. PLoS One. 2009 Jun 08; 4(6):e5821.
Score: 0.034
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Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling. Int J Radiat Biol. 2009 May; 85(5):421-31.
Score: 0.034
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YTHDF2/m6 A/NF-?B axis controls anti-tumor immunity by regulating intratumoral Tregs. EMBO J. 2023 08 01; 42(15):e113126.
Score: 0.022
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Vascular endothelial growth factor enhances endothelial cell survival and tumor radioresistance. Cancer J. 2002 Jan-Feb; 8(1):47-54.
Score: 0.020
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Angiostatin effects on endothelial cells mediated by ceramide and RhoA. EMBO Rep. 2001 Jun; 2(6):536-40.
Score: 0.019
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Interaction of hematopoietic progenitor kinase 1 and c-Abl tyrosine kinase in response to genotoxic stress. J Biol Chem. 2001 May 25; 276(21):18130-8.
Score: 0.019
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Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells. Nat Commun. 2020 09 14; 11(1):4591.
Score: 0.019
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Fecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity. Nat Commun. 2020 05 11; 11(1):2354.
Score: 0.018
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Non-canonical NF-?B Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy. Immunity. 2018 09 18; 49(3):490-503.e4.
Score: 0.016
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Nanoscale metal-organic frameworks enhance radiotherapy to potentiate checkpoint blockade immunotherapy. Nat Commun. 2018 06 15; 9(1):2351.
Score: 0.016
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JAK2 Inhibitor SAR302503 Abrogates PD-L1 Expression and Targets Therapy-Resistant Non-small Cell Lung Cancers. Mol Cancer Ther. 2018 04; 17(4):732-739.
Score: 0.016
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Host STING-dependent MDSC mobilization drives extrinsic radiation resistance. Nat Commun. 2017 11 23; 8(1):1736.
Score: 0.015
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Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein a Signaling. Immunity. 2017 08 15; 47(2):363-373.e5.
Score: 0.015
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CD95/Fas Increases Stemness in Cancer Cells by Inducing a STAT1-Dependent Type I Interferon Response. Cell Rep. 2017 03 07; 18(10):2373-2386.
Score: 0.015
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Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs. Oncotarget. 2016 May 03; 7(18):26496-515.
Score: 0.014
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Cross-talk between ceramide and PKC activity in the control of apoptosis in WEHI-231. Adv Exp Med Biol. 1996; 406:39-55.
Score: 0.013
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Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells. EMBO J. 1995 Dec 15; 14(24):6148-56.
Score: 0.013
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Role of GADD45a in murine models of radiation- and bleomycin-induced lung injury. Am J Physiol Lung Cell Mol Physiol. 2015 Dec 15; 309(12):L1420-9.
Score: 0.013
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Blockage of the early events of mitogenic signaling by interferon-gamma in macrophages in response to colony-stimulating factor-1. Blood. 1995 Oct 01; 86(7):2774-88.
Score: 0.013
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From DNA Damage to Nucleic Acid Sensing: A Strategy to Enhance Radiation Therapy. Clin Cancer Res. 2016 Jan 01; 22(1):20-5.
Score: 0.013
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Cellular and molecular mechanisms of radioresistance. Cancer Treat Res. 1995; 74:131-40.
Score: 0.012
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Radiation induction of immediate early genes: effectors of the radiation-stress response. Int J Radiat Oncol Biol Phys. 1994 Aug 30; 30(1):229-34.
Score: 0.012
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Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas. Clin Cancer Res. 2015 Feb 01; 21(3):632-41.
Score: 0.012
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Ketoconazole attenuates radiation-induction of tumor necrosis factor. Int J Radiat Oncol Biol Phys. 1994 Jul 01; 29(4):777-80.
Score: 0.012
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Molecular targets to overcome radioresistance. Semin Oncol. 1992 Aug; 19(4 Suppl 11):14-20.
Score: 0.011
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Inhibition of serine palmitoyltransferase delays the onset of radiation-induced pulmonary fibrosis through the negative regulation of sphingosine kinase-1 expression. J Lipid Res. 2012 Aug; 53(8):1553-68.
Score: 0.010
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cis-Diamminedichloroplatinum(II) induces c-jun expression in human myeloid leukemia cells: potential involvement of a protein kinase C-dependent signaling pathway. Cancer Res. 1992 Feb 15; 52(4):878-82.
Score: 0.010
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Mg ATP and antioxidants augment the radioprotective effect of surfactant copolymers. Health Phys. 2011 Dec; 101(6):731-8.
Score: 0.010
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SOD2-mediated adaptive responses induced by low-dose ionizing radiation via TNF signaling and amifostine. Free Radic Biol Med. 2011 Nov 15; 51(10):1918-25.
Score: 0.010
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Activation of a CrmA-insensitive, p35-sensitive pathway in ionizing radiation-induced apoptosis. J Biol Chem. 1997 Jan 17; 272(3):1965-9.
Score: 0.004