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Somnath Mukherjee

TitlePostdoctoral Scholar
InstitutionUniversity of Chicago
DepartmentBiochemistry and Molecular Biology
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Jones CM, Ng WH, Tincknell L, McClurg DP, Adam E, Bhandari P, Campbell K, Chambers P, Ciccarelli F, Coleman HG, Crosby T, Doyle C, Dunn JM, Elliott J, Fitzgerald RC, Foley KG, Goh V, Grabsch HI, Graham TA, Grocott M, Gwynne S, Harvey J, Jansen M, Lagergren P, Lamb C, Leigh-Doyle L, Malik F, Mayland C, McCord M, Moss A, Mukherjee S, Petty R, Rananaware S, Reid J, Rubin G, Smyth E, Trudgill NJ, Turkington RC, Underwood TJ, Walter FM, Williams J, Peters CJ. Research priorities for cancers of the oesophagus and stomach: recommendations from a UK and Ireland patient and healthcare professional partnership exercise. Gut. 2025 Nov 10; 74(12):1949-1961. PMID: 40947137; PMCID: PMC12703242.
      Citations:    Fields:    Translation:Humans
    2. Chen Q, Schafer CT, Mukherjee S, Wang K, Gustavsson M, Fuller JR, Tepper K, Lamme TD, Aydin Y, Agrawal P, Terashi G, Yao XQ, Kihara D, Kossiakoff AA, Handel TM, Tesmer JJG. Effect of phosphorylation barcodes on arrestin binding to a chemokine receptor. Nature. 2025 Jul; 643(8070):280-287. PMID: 40399676; PMCID: PMC12445016.
      Citations: 2     Fields:    Translation:HumansCells
    3. Srivastava S, Sekar G, Ojoawo A, Aggarwal A, Ferreira E, Uchikawa E, Yang M, Grace CR, Dey R, Lin YL, Guibao CD, Jayaraman S, Mukherjee S, Kossiakoff AA, Dong B, Myasnikov A, Moldoveanu T. Structural basis of BAK sequestration by MCL-1 in apoptosis. Mol Cell. 2025 Apr 17; 85(8):1606-1623.e10. PMID: 40187349; PMCID: PMC12086701.
      Citations: 2     Fields:    Translation:HumansCells
    4. Go S, Demetriou C, Valenzano G, Hughes S, Lanfredini S, Ferry H, Arbe-Barnes E, Sivakumar S, Bashford-Rogers R, Middleton MR, Mukherjee S, Morton J, Jones K, Neill EO. Tissue-resident natural killer cells support survival in pancreatic cancer through promotion of cDC1-CD8 T activity. Elife. 2024 Dec 10; 13. PMID: 39656086; PMCID: PMC11630822.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    5. Kiru G, Roy A, Kondal D, Chandrasekaran AM, Mukherjee S, Mohan B, Singh K, Salwa H, Christa E, Lobo AS, Mahajan G, Khanna A, Malviya A, Patil SG, Abichandani VK, Singh B, Gupta BK, Yellapantula B, Shailendra D, Sengupta S, Kumar S, Bardoloi N, Khanna M, Mishra A, Aithal K, Chavda V, Cornelius VR, Prabhakaran D, Poulter N, TOPSPIN Investigators. Treatment optimisation for blood pressure with single-pill combinations in India (TOPSPIN) - Protocol design and baseline characteristics. Int J Cardiol Cardiovasc Risk Prev. 2024 Dec; 23:200346. PMID: 39554875; PMCID: PMC11565424.
      Citations: 2     
    6. Mukherjee S, Qi C, Shaw R, Jones CM, Bridgewater JA, Radhakrishna G, Patel N, Holmes J, Virdee PS, Tranter B, Parsons P, Falk S, Wasan HS, Ajithkumar TV, Holyoake D, Roy R, Scott-Brown M, Hurt CN, O'Neill E, Sebag-Montefiore D, Maughan TS, Hawkins MA, Corrie P. Standard or high dose chemoradiotherapy, with or without the protease inhibitor nelfinavir, in patients with locally advanced pancreatic cancer: The phase 1/randomised phase 2 SCALOP-2 trial. Eur J Cancer. 2024 Sep; 209:114236. PMID: 39059185.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    7. Liu H, Zakrzewicz D, Nosol K, Irobalieva RN, Mukherjee S, Bang-Sørensen R, Goldmann N, Kunz S, Rossi L, Kossiakoff AA, Urban S, Glebe D, Geyer J, Locher KP. Structure of antiviral drug bulevirtide bound to hepatitis B and D virus receptor protein NTCP. Nat Commun. 2024 Mar 20; 15(1):2476. PMID: 38509088; PMCID: PMC10954734.
      Citations: 20     Fields:    Translation:HumansCells
    8. Ciuta AD, Nosol K, Kowal J, Mukherjee S, Ramírez AS, Stieger B, Kossiakoff AA, Locher KP. Structure of human drug transporters OATP1B1 and OATP1B3. Nat Commun. 2023 09 18; 14(1):5774. PMID: 37723174; PMCID: PMC10507018.
      Citations: 41     Fields:    Translation:Humans
    9. Chen Q, Schafer CT, Mukherjee S, Gustavsson M, Agrawal P, Yao XQ, Kossiakoff AA, Handel TM, Tesmer JJG. ACKR3-arrestin2/3 complexes reveal molecular consequences of GRK-dependent barcoding. bioRxiv. 2023 Jul 19. PMID: 37502840; PMCID: PMC10370059.
      Citations:    
    10. Mukherjee S, Hurt CN, Adams R, Bateman A, Bradley KM, Bridges S, Falk S, Griffiths G, Gwynne S, Jones CM, Markham PJ, Maughan T, Nixon LS, Radhakrishna G, Roy R, Schoenbuchner S, Sheikh H, Spezi E, Hawkins M, Crosby TDL. Efficacy of early PET-CT directed switch to carboplatin and paclitaxel based definitive chemoradiotherapy in patients with oesophageal cancer who have a poor early response to induction cisplatin and capecitabine in the UK: a multi-centre randomised controlled phase II trial. EClinicalMedicine. 2023 Jul; 61:102059. PMID: 37409323; PMCID: PMC10318451.
      Citations: 2     
    11. Kern DM, Bleier J, Mukherjee S, Hill JM, Kossiakoff AA, Isacoff EY, Brohawn SG. Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels. Nat Struct Mol Biol. 2023 06; 30(6):841-852. PMID: 36928458.
      Citations: 24     Fields:    
    12. Li N, Ji X, Mukherjee S, Yang B, Ren Y, Wang C, Chen Y. A Bioinspired Skin UV Filter with Broadband UV Protection, Photostability, and Resistance to Oxidative Damage. ACS Appl Mater Interfaces. 2023 Mar 01; 15(8):10383-10397. PMID: 36800210.
      Citations: 7     Fields:    
    13. John A, Mao R, Mukherjee S, Darbre T, Scott NE, Reymond JL, Kossiakoff AA, Goddard-Borger ED, Bloch JS, Boilevin J, Irobalieva RN, Locher KP. Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase. Nat Chem Biol. 2023 05; 19(5):575-584. PMID: 36604564; PMCID: PMC10154233.
      Citations: 16     Fields:    Translation:HumansCells
    14. Jones CM, O'Connor H, O'Donovan M, Hayward D, Blasko A, Harman R, Malhotra S, Debiram-Beecham I, Alias B, Bailey A, Bateman A, Crosby TDL, Falk S, Gollins S, Hawkins MA, Kadri S, Levy S, Radhakrishna G, Roy R, Sripadam R, Fitzgerald RC, Mukherjee S. Use of a non-endoscopic immunocytological device (Cytosponge™) for post chemoradiotherapy surveillance in patients with oesophageal cancer in the UK (CYTOFLOC): A multicentre feasibility study. EClinicalMedicine. 2022 Nov; 53:101664. PMID: 36187722; PMCID: PMC9519482.
      Citations: 3     
    15. Rosenberg JE, Park SH, Kozlov V, Dao TV, Castellano D, Li JR, Mukherjee SD, Howells K, Dry H, Lanasa MC, Stewart R, Bajorin DF. Durvalumab Plus Olaparib in Previously Untreated, Platinum-Ineligible Patients With Metastatic Urothelial Carcinoma: A Multicenter, Randomized, Phase II Trial (BAYOU). J Clin Oncol. 2023 01 01; 41(1):43-53. PMID: 35737919; PMCID: PMC9788981.
      Citations: 33     Fields:    Translation:HumansCTClinical Trials
    16. Mukherjee S, Agrawal P, Kossiakoff AA, Liu H, Irobalieva RN, Bang-Sørensen R, Nosol K, Stieger B, Locher KP. Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver. Cell Res. 2022 08; 32(8):773-776. PMID: 35726088; PMCID: PMC9343345.
      Citations: 21     Fields:    Translation:Humans
    17. Bley CJ, Nie S, Mobbs GW, Petrovic S, Gres AT, Liu X, Mukherjee S, Harvey S, Huber FM, Lin DH, Brown B, Tang AW, Rundlet EJ, Correia AR, Chen S, Regmi SG, Stevens TA, Jette CA, Dasso M, Patke A, Palazzo AF, Kossiakoff AA, Hoelz A. Architecture of the cytoplasmic face of the nuclear pore. Science. 2022 06 10; 376(6598):eabm9129. PMID: 35679405; PMCID: PMC9348906.
      Citations: 87     Fields:    Translation:HumansAnimalsCells
    18. Goodwin PJ, Chen BE, Gelmon KA, Whelan TJ, Ennis M, Lemieux J, Ligibel JA, Hershman DL, Mayer IA, Hobday TJ, Bliss JM, Rastogi P, Rabaglio-Poretti M, Mukherjee SD, Mackey JR, Abramson VG, Oja C, Wesolowski R, Thompson AM, Rea DW, Stos PM, Shepherd LE, Stambolic V, Parulekar WR. Effect of Metformin vs Placebo on Invasive Disease-Free Survival in Patients With Breast Cancer: The MA.32 Randomized Clinical Trial. JAMA. 2022 05 24; 327(20):1963-1973. PMID: 35608580; PMCID: PMC9131745.
      Citations: 122     Fields:    Translation:HumansCTClinical Trials
    19. Ura M, Mukherjee S, Marcon E, Koestler SA, Kossiakoff AA. Synthetic Antibodies Detect Distinct Cellular States of Chromosome Passenger Complex Proteins. J Mol Biol. 2022 06 30; 434(12):167602. PMID: 35469831; PMCID: PMC9862951.
      Citations: 1     Fields:    Translation:HumansCells
    20. Mukherjee S, Filippova EV, Pardon E, Steyaert J, Kossiakoff AA, Bloch JS, Kowal J, Niederer M, Locher KP. Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins. Proc Natl Acad Sci U S A. 2021 11 23; 118(47). PMID: 34782475; PMCID: PMC8617411.
      Citations: 55     Fields:    Translation:AnimalsCells
    21. Yan Y, Mukherjee S, Harikumar KG, Strutzenberg TS, Zhou XE, Suino-Powell K, Xu TH, Sheldon RD, Lamp J, Brunzelle JS, Radziwon K, Ellis A, Novick SJ, Vega IE, Jones RG, Miller LJ, Xu HE, Griffin PR, Kossiakoff AA, Melcher K. Structure of an AMPK complex in an inactive, ATP-bound state. Science. 2021 07 23; 373(6553):413-419. PMID: 34437114; PMCID: PMC8428800.
      Citations: 58     Fields:    Translation:HumansCells
    22. Alhussein MM, Mokbel A, Cosman T, Aghel N, Yang EH, Mukherjee SD, Dent S, Ellis PM, Dhesy-Thind S, Leong DP. Pertuzumab Cardiotoxicity in Patients With HER2-Positive Cancer: A Systematic Review and Meta-analysis. CJC Open. 2021 Nov; 3(11):1372-1382. PMID: 34901806; PMCID: PMC8640623.
      Citations: 32     
    23. Chen Q, Plasencia M, Li Z, Mukherjee S, Patra D, Chen CL, Klose T, Yao XQ, Kossiakoff AA, Chang L, Andrews PC, Tesmer JJG. Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1. Nature. 2021 07; 595(7868):600-605. PMID: 34262173; PMCID: PMC8607881.
      Citations: 49     Fields:    Translation:AnimalsCells
    24. Goulart MR, Watt J, Siddiqui I, Lawlor RT, Imrali A, Hughes C, Saad A, ChinAleong J, Hurt C, Cox C, Salvia R, Mantovani A, Crnogorac-Jurcevic T, Mukherjee S, Scarpa A, Allavena P, Kocher HM. Pentraxin 3 is a stromally-derived biomarker for detection of pancreatic ductal adenocarcinoma. NPJ Precis Oncol. 2021 Jun 29; 5(1):61. PMID: 34188166; PMCID: PMC8242009.
      Citations: 17     
    25. Mukherjee S, Hurt C, Radhakrishna G, Gwynne S, Bateman A, Gollins S, Hawkins MA, Canham J, Grabsch HI, Falk S, Sharma RA, Ray R, Roy R, Cox C, Maynard N, Nixon L, Sebag-Montefiore DJ, Maughan T, Griffiths GO, Crosby TDL. Oxaliplatin/capecitabine or carboplatin/paclitaxel-based preoperative chemoradiation for resectable oesophageal adenocarcinoma (NeoSCOPE): Long-term results of a randomised controlled trial. Eur J Cancer. 2021 08; 153:153-161. PMID: 34157617; PMCID: PMC8330696.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    26. Eyres M, Lanfredini S, Xu H, Burns A, Blake A, Willenbrock F, Goldin R, Hughes D, Hughes S, Thapa A, Vavoulis D, Hubert A, D'Costa Z, Sabbagh A, Abraham AG, Blancher C, Jones S, Verrill C, Silva M, Soonawalla Z, Maughan T, Schuh A, Mukherjee S, O'Neill E. TET2 Drives 5hmc Marking of GATA6 and Epigenetically Defines Pancreatic Ductal Adenocarcinoma Transcriptional Subtypes. Gastroenterology. 2021 08; 161(2):653-668.e16. PMID: 33915173.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    27. Balana AT, Levine PM, Craven TW, Mukherjee S, Pedowitz NJ, Moon SP, Takahashi TT, Becker CFW, Baker D, Pratt MR. O-GlcNAc modification of small heat shock proteins enhances their anti-amyloid chaperone activity. Nat Chem. 2021 05; 13(5):441-450. PMID: 33723378; PMCID: PMC8102337.
      Citations: 48     Fields:    Translation:Humans
    28. Holyoake DLP, Robinson M, Silva M, Grose D, McIntosh D, Sebag-Montefiore D, Radhakrishna G, Mukherjee S, Hawkins MA. SPARC, a phase-I trial of pre-operative, margin intensified, stereotactic body radiation therapy for pancreatic cancer. Radiother Oncol. 2021 02; 155:278-284. PMID: 33217498.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    29. Jones CM, Radhakrishna G, Aitken K, Bridgewater J, Corrie P, Eatock M, Goody R, Ghaneh P, Good J, Grose D, Holyoake D, Hunt A, Jamieson NB, Palmer DH, Soonawalla Z, Valle JW, Hawkins MA, Mukherjee S. Reply to Comment on "The UK consensus position on the treatment of pancreatic cancer during the COVID-19 pandemic". Br J Cancer. 2021 02; 124(3):679-680. PMID: 33139799; PMCID: PMC7851158.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    30. Powles T, van der Heijden MS, Castellano D, Galsky MD, Loriot Y, Petrylak DP, Ogawa O, Park SH, Lee JL, De Giorgi U, Bögemann M, Bamias A, Eigl BJ, Gurney H, Mukherjee SD, Fradet Y, Skoneczna I, Tsiatas M, Novikov A, Suárez C, Fay AP, Duran I, Necchi A, Wildsmith S, He P, Angra N, Gupta AK, Levin W, Bellmunt J, DANUBE study investigators. Durvalumab alone and durvalumab plus tremelimumab versus chemotherapy in previously untreated patients with unresectable, locally advanced or metastatic urothelial carcinoma (DANUBE): a randomised, open-label, multicentre, phase 3 trial. Lancet Oncol. 2020 12; 21(12):1574-1588. PMID: 32971005.
      Citations: 237     Fields:    Translation:HumansCTClinical Trials
    31. Brunner TB, Haustermans K, Huguet F, Morganti AG, Mukherjee S, Belka C, Krempien R, Hawkins MA, Valentini V, Roeder F. ESTRO ACROP guidelines for target volume definition in pancreatic cancer. Radiother Oncol. 2021 01; 154:60-69. PMID: 32861703.
      Citations: 37     Fields:    Translation:Humans
    32. Thomson DJ, Yom SS, Saeed H, El Naqa I, Ballas L, Bentzen SM, Chao ST, Choudhury A, Coles CE, Dover L, Guadagnolo BA, Guckenberger M, Hoskin P, Jabbour SK, Katz MS, Mukherjee S, Rembielak A, Sebag-Montefiore D, Sher DJ, Terezakis SA, Thomas TV, Vogel J, Estes C. Radiation Fractionation Schedules Published During the COVID-19 Pandemic: A Systematic Review of the Quality of Evidence and Recommendations for Future Development. Int J Radiat Oncol Biol Phys. 2020 Oct 01; 108(2):379-389. PMID: 32798063; PMCID: PMC7834196.
      Citations: 31     Fields:    Translation:HumansPHPublic Health
    33. Tsutsumi N, Mukherjee S, Waghray D, Janda CY, Jude KM, Miao Y, Burg JS, Aduri NG, Kossiakoff AA, Gati C, Garcia KC. Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling. Elife. 2020 08 07; 9. PMID: 32762848; PMCID: PMC7442489.
      Citations: 69     Fields:    Translation:HumansCells
    34. Jones CM, Radhakrishna G, Aitken K, Bridgewater J, Corrie P, Eatock M, Goody R, Ghaneh P, Good J, Grose D, Holyoake D, Hunt A, Jamieson NB, Palmer DH, Soonawalla Z, Valle JW, Hawkins MA, Mukherjee S. Considerations for the treatment of pancreatic cancer during the COVID-19 pandemic: the UK consensus position. Br J Cancer. 2020 09; 123(5):709-713. PMID: 32641867; PMCID: PMC7341025.
      Citations: 18     Fields:    Translation:HumansCellsPHPublic Health
    35. Zhang D, Wang B, Sun Y, Wang C, Mukherjee S, Yang C, Chen Y. Injectable Enzyme-Based Hydrogel Matrix with Precisely Oxidative Stress Defense for Promoting Dermal Repair of Burn Wound. Macromol Biosci. 2020 06; 20(6):e2000036. PMID: 32239626.
      Citations: 9     Fields:    Translation:AnimalsCells
    36. Mukherjee S, Erramilli SK, Ammirati M, Alvarez FJD, Fennell KF, Purdy MD, Skrobek BM, Radziwon K, Coukos J, Kang Y, Dutka P, Gao X, Qiu X, Yeager M, Eric Xu H, Han S, Kossiakoff AA. Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins. Nat Commun. 2020 03 27; 11(1):1598. PMID: 32221310; PMCID: PMC7101349.
      Citations: 55     Fields:    Translation:HumansCells
    37. Zhang D, Cai G, Mukherjee S, Sun Y, Wang C, Mai B, Liu K, Yang C, Chen Y. Elastic, Persistently Moisture-Retentive, and Wearable Biomimetic Film Inspired by Fetal Scarless Repair for Promoting Skin Wound Healing. ACS Appl Mater Interfaces. 2020 Feb 05; 12(5):5542-5556. PMID: 31939277.
      Citations: 12     Fields:    Translation:AnimalsCells
    38. Knight JC, Goldin R, Mosley M, Dias GM, Bravo LC, Kersemans V, Allen PD, Mukherjee S, Smart S, Cornelissen B, Torres JB. Early Detection in a Mouse Model of Pancreatic Cancer by Imaging DNA Damage Response Signaling. J Nucl Med. 2020 07; 61(7):1006-1013. PMID: 31862800; PMCID: PMC7383084.
      Citations: 7     Fields:    Translation:AnimalsCells
    39. Chu KY, Cooke R, Van den Heuvel F, Mukherjee S, Hawkins MA. Impact of abdominal compression on setup error and image matching during radical abdominal radiotherapy. Tech Innov Patient Support Radiat Oncol. 2019 Dec; 12:28-33. PMID: 32095552; PMCID: PMC7033789.
      Citations: 4     
    40. Dutka P, Mukherjee S, Gao X, Kang Y, de Waal PW, Wang L, Zhuang Y, Melcher K, Zhang C, Xu HE, Kossiakoff AA. Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM. Structure. 2019 12 03; 27(12):1862-1874.e7. PMID: 31669042; PMCID: PMC7297049.
      Citations: 16     Fields:    Translation:HumansCells
    41. Warren M, Kolinsky M, Canil CM, Czaykowski P, Sridhar SS, Black PC, Booth CM, Kassouf W, Eapen L, Mukherjee SD, Blais N, Eigl BJ, Winquist E, Basappa NS, North SA, GUMOC. Canadian Urological Association/Genitourinary Medical Oncologists of Canada consensus statement: Management of unresectable locally advanced and metastatic urothelial carcinoma. Can Urol Assoc J. 2019 10; 13(10):318-327. PMID: 31059420; PMCID: PMC6788915.
      Citations: 9     
    42. Liu K, Gao S, Zheng Z, Deng X, Mukherjee S, Wang S, Xu H, Wang J, Liu J, Zhai T, Fang Y. Spatially Confined Growth of Fullerene to Super-Long Crystalline Fibers in Supramolecular Gels for High-Performance Photodetector. Adv Mater. 2019 May; 31(18):e1808254. PMID: 30873680.
      Citations: 5     Fields:    
    43. Strauss VY, Shaw R, Virdee PS, Hurt CN, Ward E, Tranter B, Patel N, Bridgewater J, Parsons P, Radhakrishna G, O'Neill E, Sebag-Montefiore D, Hawkins M, Corrie PG, Maughan T, Mukherjee S. Study protocol: a multi-centre randomised study of induction chemotherapy followed by capecitabine ± nelfinavir with high- or standard-dose radiotherapy for locally advanced pancreatic cancer (SCALOP-2). BMC Cancer. 2019 Feb 04; 19(1):121. PMID: 30717707; PMCID: PMC6360784.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    44. O'Reilly D, Fou L, Hasler E, Hawkins J, O'Connell S, Pelone F, Callaway M, Campbell F, Capel M, Charnley R, Corrie P, Elliot D, Goodburn L, Jewell A, Joharchi S, McGeeney L, Mukherjee S, Oppong K, Whelan P, Primrose J, Neoptolemos J. Diagnosis and management of pancreatic cancer in adults: A summary of guidelines from the UK National Institute for Health and Care Excellence. Pancreatology. 2018 Dec; 18(8):962-970. PMID: 30292643.
      Citations: 50     Fields:    Translation:Humans
    45. Zhang D, Yang C, Niu Z, Wang C, Mukherjee S, Wang D, Li X, Liu R, Gao J, Chen Y. Construction of Crowning ß-cyclodextrin with Temperature Response and Efficient Properties of Host-Guest Inclusion. Langmuir. 2018 09 25; 34(38):11567-11574. PMID: 30153028.
      Citations: 2     Fields:    Translation:Cells
    46. Kang Y, Kuybeda O, de Waal PW, Mukherjee S, Van Eps N, Dutka P, Zhou XE, Bartesaghi A, Erramilli S, Morizumi T, Gu X, Yin Y, Liu P, Jiang Y, Meng X, Zhao G, Melcher K, Ernst OP, Kossiakoff AA, Subramaniam S, Xu HE. Publisher Correction: Cryo-EM structure of human rhodopsin bound to an inhibitory G protein. Nature. 2018 09; 561(7724):E44. PMID: 29930353.
      Citations: 1     Fields:    
    47. Kang Y, Kuybeda O, de Waal PW, Mukherjee S, Van Eps N, Dutka P, Zhou XE, Bartesaghi A, Erramilli S, Morizumi T, Gu X, Yin Y, Liu P, Jiang Y, Meng X, Zhao G, Melcher K, Ernst OP, Kossiakoff AA, Subramaniam S, Xu HE. Cryo-EM structure of human rhodopsin bound to an inhibitory G protein. Nature. 2018 06; 558(7711):553-558. PMID: 29899450; PMCID: PMC8054211.
      Citations: 149     Fields:    Translation:HumansCells
    48. Kossiakoff AA, Mukherjee S, Horn JR. Reply to Kang and Brooks: Comment on the calculations in protein thermodynamics. J Biol Chem. 2018 04 06; 293(14):5063. PMID: 29626107; PMCID: PMC5892581.
      Citations:    Fields:    
    49. Mukherjee S, Griffin DH, Horn JR, Rizk SS, Nocula-Lugowska M, Malmqvist M, Kim SS, Kossiakoff AA. Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins. J Biol Chem. 2018 02 23; 293(8):2815-2828. PMID: 29321208; PMCID: PMC5827440.
      Citations: 20     Fields:    Translation:Cells
    50. Cox S, Hurt C, Grenader T, Mukherjee S, Bridgewater J, Crosby T. The prognostic value of derived neutrophil to lymphocyte ratio in oesophageal cancer treated with definitive chemoradiotherapy. Radiother Oncol. 2017 10; 125(1):154-159. PMID: 28893415; PMCID: PMC5648078.
      Citations: 17     Fields:    Translation:HumansCells
    51. Knight JC, Mosley MJ, Bravo LC, Kersemans V, Allen PD, Mukherjee S, O'Neill E, Cornelissen B. 89Zr-anti-?H2AX-TAT but not 18F-FDG Allows Early Monitoring of Response to Chemotherapy in a Mouse Model of Pancreatic Ductal Adenocarcinoma. Clin Cancer Res. 2017 Nov 01; 23(21):6498-6504. PMID: 28774899.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    52. Holyoake DLP, Aznar M, Mukherjee S, Partridge M, Hawkins MA. Modelling duodenum radiotherapy toxicity using cohort dose-volume-histogram data. Radiother Oncol. 2017 06; 123(3):431-437. PMID: 28600084; PMCID: PMC5486774.
      Citations: 13     Fields:    Translation:HumansPHPublic Health
    53. Virdee P, Shaw R, Strauss V, Hamill C, Hurt C, Gwynne S, Corrie P, Bridgewater J, Parsons P, Tranter B, Sebag-Montefiore D, Chu KY, Radhakrishna G, Hawkins M, O'Neill E, Campbell S, Love S, Maughan T, Mukherjee S. SCALOP-2: A multi-centre randomised study of induction chemotherapy followed by capecitabine (+/- nelfinavir) with high or standard dose radiotherapy for locally advanced non-metastatic pancreatic cancer. Ann Oncol. 2017 Jun; 28 Suppl 3:iii82-iii83. PMID: 32136037.
      Citations:    
    54. Lohmann AE, Liebman MF, Brien W, Parulekar WR, Gelmon KA, Shepherd LE, Ligibel JA, Hershman DL, Rastogi P, Mayer IA, Hobday TJ, Lemieux J, Thompson AM, Pritchard KI, Whelan TJ, Mukherjee SD, Chalchal HI, Bernstein V, Stambolic V, Chen BE, Goodwin PJ, From the CCTG, Alliance, SWOG, ECOG, NSABP Cooperative Groups. Effects of metformin versus placebo on vitamin B12 metabolism in non-diabetic breast cancer patients in CCTG MA.32. Breast Cancer Res Treat. 2017 Jul; 164(2):371-378. PMID: 28447237; PMCID: PMC5798974.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    55. Rizk SS, Mukherjee S, Koide A, Koide S, Kossiakoff AA. Targeted rescue of cancer-associated IDH1 mutant activity using an engineered synthetic antibody. Sci Rep. 2017 04 03; 7(1):556. PMID: 28373671; PMCID: PMC5429742.
      Citations: 4     Fields:    Translation:HumansCells
    56. Chi KN, Higano CS, Blumenstein B, Ferrero JM, Reeves J, Feyerabend S, Gravis G, Merseburger AS, Stenzl A, Bergman AM, Mukherjee SD, Zalewski P, Saad F, Jacobs C, Gleave M, de Bono JS. Custirsen in combination with docetaxel and prednisone for patients with metastatic castration-resistant prostate cancer (SYNERGY trial): a phase 3, multicentre, open-label, randomised trial. Lancet Oncol. 2017 04; 18(4):473-485. PMID: 28283282.
      Citations: 47     Fields:    Translation:HumansCTClinical Trials
    57. Krishnan BP, Raghu S, Mukherjee S, Sureshan KM. Organogel-assisted topochemical synthesis of multivalent glyco-polymer for high-affinity lectin binding. Chem Commun (Camb). 2016 Dec 01; 52(98):14089-14092. PMID: 27853762.
      Citations: 4     Fields:    Translation:Cells
    58. Leszczynska KB, Dobrynin G, Leslie RE, Ient J, Boumelha AJ, Senra JM, Hawkins MA, Maughan T, Mukherjee S, Hammond EM. Preclinical testing of an Atr inhibitor demonstrates improved response to standard therapies for esophageal cancer. Radiother Oncol. 2016 11; 121(2):232-238. PMID: 27839769; PMCID: PMC5154234.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    59. Holyoake DL, Ward E, Grose D, McIntosh D, Sebag-Montefiore D, Radhakrishna G, Patel N, Silva M, Mukherjee S, Strauss VY, Odondi L, Fokas E, Melcher A, Hawkins MA. A phase-I trial of pre-operative, margin intensive, stereotactic body radiation therapy for pancreatic cancer: the 'SPARC' trial protocol. BMC Cancer. 2016 09 13; 16(1):728. PMID: 27619800; PMCID: PMC5020462.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    60. Balaban EP, Mangu PB, Khorana AA, Shah MA, Mukherjee S, Crane CH, Javle MM, Eads JR, Allen P, Ko AH, Engebretson A, Herman JM, Strickler JH, Benson AB, Urba S, Yee NS. Locally Advanced, Unresectable Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline. J Clin Oncol. 2016 08 01; 34(22):2654-68. PMID: 27247216.
      Citations: 174     Fields:    Translation:Humans
    61. Kundu P, Biswas R, Mukherjee S, Reinhard L, Dutta A, Mueller-Dieckmann J, Weiss MS, Pal NK, Das AK. Structure-based Epitope Mapping of Mycobacterium tuberculosis Secretary Antigen MTC28. J Biol Chem. 2016 Jul 01; 291(27):13943-13954. PMID: 27189947; PMCID: PMC4933155.
      Citations: 4     Fields:    Translation:Cells
    62. Wilson JM, Fokas E, Dutton SJ, Patel N, Hawkins MA, Eccles C, Chu KY, Durrant L, Abraham AG, Partridge M, Woodward M, O'Neill E, Maughan T, McKenna WG, Mukherjee S, Brunner TB. ARCII: A phase II trial of the HIV protease inhibitor Nelfinavir in combination with chemoradiation for locally advanced inoperable pancreatic cancer. Radiother Oncol. 2016 05; 119(2):306-11. PMID: 27117177; PMCID: PMC4917892.
      Citations: 34     Fields:    Translation:HumansCTClinical Trials
    63. Hill EJ, Roberts C, Franklin JM, Enescu M, West N, MacGregor TP, Chu KY, Boyle L, Blesing C, Wang LM, Mukherjee S, Anderson EM, Brown G, Dutton S, Love SB, Schnabel JA, Quirke P, Muschel R, McKenna WG, Partridge M, Sharma RA. Clinical Trial of Oral Nelfinavir before and during Radiation Therapy for Advanced Rectal Cancer. Clin Cancer Res. 2016 Apr 15; 22(8):1922-31. PMID: 26861457; PMCID: PMC4835023.
      Citations: 25     Fields:    Translation:HumansCTClinical Trials
    64. Fokas E, Clifford C, Spezi E, Joseph G, Branagan J, Hurt C, Nixon L, Abrams R, Staffurth J, Mukherjee S. Comparison of investigator-delineated gross tumor volumes and quality assurance in pancreatic cancer: Analysis of the pretrial benchmark case for the SCALOP trial. Radiother Oncol. 2015 Dec; 117(3):432-7. PMID: 26328939.
      Citations: 12     Fields:    Translation:HumansCTClinical Trials
    65. Hurt CN, Mukherjee S, Bridgewater J, Falk S, Crosby T, McDonald A, Joseph G, Staffurth J, Abrams RA, Blazeby JM, Bridges S, Dutton P, Griffiths G, Maughan T, Johnson C. Health-Related Quality of Life in SCALOP, a Randomized Phase 2 Trial Comparing Chemoradiation Therapy Regimens in Locally Advanced Pancreatic Cancer. Int J Radiat Oncol Biol Phys. 2015 Nov 15; 93(4):810-8. PMID: 26530749; PMCID: PMC4627359.
      Citations: 13     Fields:    Translation:HumansCTClinical Trials
    66. Anbalagan S, Biasoli D, Leszczynska KB, Mukherjee S, Hammond EM. In Vitro Radiosensitization of Esophageal Cancer Cells with the Aminopeptidase Inhibitor CHR-2797. Radiat Res. 2015 Sep; 184(3):259-65. PMID: 26291737.
      Citations: 5     Fields:    Translation:HumansCells
    67. Mukherjee S, Ura M, Hoey RJ, Kossiakoff AA. A New Versatile Immobilization Tag Based on the Ultra High Affinity and Reversibility of the Calmodulin-Calmodulin Binding Peptide Interaction. J Mol Biol. 2015 Aug 14; 427(16):2707-25. PMID: 26159704; PMCID: PMC4523416.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    68. Goodwin PJ, Parulekar WR, Gelmon KA, Shepherd LE, Ligibel JA, Hershman DL, Rastogi P, Mayer IA, Hobday TJ, Lemieux J, Thompson AM, Pritchard KI, Whelan TJ, Mukherjee SD, Chalchal HI, Oja CD, Tonkin KS, Bernstein V, Chen BE, Stambolic V. Effect of metformin vs placebo on and metabolic factors in NCIC CTG MA.32. J Natl Cancer Inst. 2015 Mar; 107(3). PMID: 25740979; PMCID: PMC4565534.
      Citations: 72     Fields:    Translation:HumansCTClinical Trials
    69. Mukherjee S, Hurt CN, Gwynne S, Bateman A, Gollins S, Radhakrishna G, Hawkins M, Canham J, Lewis W, Grabsch HI, Sharma RA, Wade W, Maggs R, Tranter B, Roberts A, Sebag-Montefiore D, Maughan T, Griffiths G, Crosby T. NEOSCOPE: a randomised Phase II study of induction chemotherapy followed by either oxaliplatin/capecitabine or paclitaxel/carboplatin based chemoradiation as pre-operative regimen for resectable oesophageal adenocarcinoma. BMC Cancer. 2015 Feb 12; 15:48. PMID: 25880814; PMCID: PMC4329217.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    70. Roychowdhury A, Kundu A, Bose M, Gujar A, Mukherjee S, Das AK. Complete catalytic cycle of cofactor-independent phosphoglycerate mutase involves a spring-loaded mechanism. FEBS J. 2015 Mar; 282(6):1097-110. PMID: 25611430.
      Citations: 5     Fields:    Translation:Cells
    71. Rizk SS, Kouadio JL, Szymborska A, Duguid EM, Mukherjee S, Zheng J, Clevenger CV, Kossiakoff AA. Engineering synthetic antibody binders for allosteric inhibition of prolactin receptor signaling. Cell Commun Signal. 2015 Jan 15; 13:1. PMID: 25589173; PMCID: PMC4300558.
      Citations: 11     Fields:    Translation:HumansCells
    72. Wilson JM, Mukherjee S, Chu KY, Brunner TB, Partridge M, Hawkins M. Challenges in using ¹8F-fluorodeoxyglucose-PET-CT to define a biological radiotherapy boost volume in locally advanced pancreatic cancer. Radiat Oncol. 2014 Jun 24; 9:146. PMID: 24962658; PMCID: PMC4078370.
      Citations: 7     Fields:    Translation:Humans
    73. Mukherjee S, Hurt CN, Bridgewater J, Falk S, Cummins S, Wasan H, Crosby T, Jephcott C, Roy R, Radhakrishna G, McDonald A, Ray R, Joseph G, Staffurth J, Abrams RA, Griffiths G, Maughan T. Gemcitabine-based or capecitabine-based chemoradiotherapy for locally advanced pancreatic cancer (SCALOP): a multicentre, randomised, phase 2 trial. Lancet Oncol. 2013 Apr; 14(4):317-26. PMID: 23474363; PMCID: PMC3620899.
      Citations: 156     Fields:    Translation:HumansCTClinical Trials
    74. Ryan CJ, Smith MR, de Bono JS, Molina A, Logothetis CJ, de Souza P, Fizazi K, Mainwaring P, Piulats JM, Ng S, Carles J, Mulders PF, Basch E, Small EJ, Saad F, Schrijvers D, Van Poppel H, Mukherjee SD, Suttmann H, Gerritsen WR, Flaig TW, George DJ, Yu EY, Efstathiou E, Pantuck A, Winquist E, Higano CS, Taplin ME, Park Y, Kheoh T, Griffin T, Scher HI, Rathkopf DE, COU-AA-302 Investigators. Abiraterone in metastatic prostate cancer without previous chemotherapy. N Engl J Med. 2013 Jan 10; 368(2):138-48. PMID: 23228172; PMCID: PMC3683570.
      Citations: 1228     Fields:    Translation:Humans
    75. Mukherjee S, Dutta D, Saha B, Das AK. Crystal structure of glyceraldehyde-3-phosphate dehydrogenase 1 from methicillin-resistant Staphylococcus aureus MRSA252 provides novel insights into substrate binding and catalytic mechanism. J Mol Biol. 2010 Sep 03; 401(5):949-68. PMID: 20620151.
      Citations: 26     Fields:    Translation:Cells
    76. Mukherjee S, Dhar R, Das AK. Analyzing the catalytic mechanism of protein tyrosine phosphatase PtpB from Staphylococcus aureus through site-directed mutagenesis. Int J Biol Macromol. 2009 Dec 01; 45(5):463-9. PMID: 19747503.
      Citations: 3     Fields:    Translation:Cells
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