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Alan Leff

TitleEmeritus/Emerita
InstitutionUniversity of Chicago
DepartmentMedicine
AddressChicago IL 60637
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    Collapse Research 
    Collapse research activities and funding
    R01HL085779     (LEFF, ALAN RICHARD)Apr 1, 2007 - Jan 31, 2011
    NIH
    Transcellular Communication in Airway Inflammation and Airway Hyperresponsiveness
    Role: Principal Investigator
    U01AI034566     (LEFF, ALAN)Aug 1, 1993 - Jul 31, 1998
    NIH
    AIRWAY BIOLOGY OF ASTHMA
    Role: Principal Investigator
    R01HL046368     (LEFF, ALAN RICHARD)Apr 1, 1991 - Mar 31, 2007
    NIH
    MECHANISMS OF AIRWAY HYPERRESPONSIVENESS
    Role: Principal Investigator
    R01HL035718     (LEFF, ALAN)Sep 30, 1985 - Nov 30, 1996
    NIH
    MATURATIONAL CORRELATES OF AIRWAY CONTRACTION
    Role: Principal Investigator
    R01HL032495     (LEFF, ALAN)Jul 1, 1985 - Jun 30, 1994
    NIH
    AUTONOMIC REGULATION OF RESPIRATORY MUSCLE &SECRETION
    Role: Principal Investigator
    K04HL001398     (LEFF, ALAN)Jul 15, 1984 - Jul 14, 1989
    NIH
    AUTONOMIC PHARMACOLOGY OF RESPIRATORY MUSCLE &SECRETION
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Li J, Wang H, Zhong Q, Zhu X, Chen SJ, Qian Y, Costakis J, Bunney G, Beiser DG, Leff AR, Lewandowski ED, Vanden Hoek TL, ÓDonnell JM. A novel pharmacological strategy by PTEN inhibition for improving metabolic resuscitation and survival after mouse cardiac arrest. Am J Physiol Heart Circ Physiol. 2015 Jun 01; 308(11):H1414-22. PMID: 25795713; PMCID: PMC4451301.
      Citations: 13     Fields:    Translation:Animals
    2. Meng F, Mambetsariev I, Tian Y, Beckham Y, Meliton A, Leff A, Gardel ML, Allen MJ, Birukov KG, Birukova AA. Attenuation of lipopolysaccharide-induced lung vascular stiffening by lipoxin reduces lung inflammation. Am J Respir Cell Mol Biol. 2015 Feb; 52(2):152-61. PMID: 24992633; PMCID: PMC4370244.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    3. Zhu X, Shao ZH, Li C, Li J, Zhong Q, Learoyd J, Meliton A, Meliton L, Leff AR, Vanden Hoek TL. TAT-protein blockade during ischemia/reperfusion reveals critical role for p85 PI3K-PTEN interaction in cardiomyocyte injury. PLoS One. 2014; 9(4):e95622. PMID: 24752319; PMCID: PMC3994094.
      Citations: 8     Fields:    Translation:AnimalsCells
    4. Meliton AY, Meliton LN, Birukova AA, Leff AR, Birukov KG, Muñoz NM. Mechanical induction of group V phospholipase A(2) causes lung inflammation and acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2013 May 15; 304(10):L689-700. PMID: 23525785; PMCID: PMC3652060.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    5. Kratzer E, Tian Y, Sarich N, Wu T, Meliton A, Leff A, Birukova AA. Oxidative stress contributes to lung injury and barrier dysfunction via microtubule destabilization. Am J Respir Cell Mol Biol. 2012 Nov; 47(5):688-97. PMID: 22842495; PMCID: PMC3547103.
      Citations: 70     Fields:    Translation:HumansAnimalsCells
    6. Birukova AA, Wu T, Tian Y, Meliton A, Sarich N, Tian X, Leff A, Birukov KG. Iloprost improves endothelial barrier function in lipopolysaccharide-induced lung injury. Eur Respir J. 2013 Jan; 41(1):165-76. PMID: 22790920; PMCID: PMC3661223.
      Citations: 40     Fields:    Translation:AnimalsCells
    7. Desai A, Meliton LN, Meliton AY, Zhou T, Leff AR, Dudek SM, Muñoz NM. Group V phospholipase A(2) increases pulmonary endothelial permeability through direct hydrolysis of the cell membrane. Pulm Circ. 2012 Apr-Jun; 2(2):182-92. PMID: 22837859; PMCID: PMC3401872.
      Citations: 9     
    8. Birukova AA, Tian Y, Meliton A, Leff A, Wu T, Birukov KG. Stimulation of Rho signaling by pathologic mechanical stretch is a "second hit" to Rho-independent lung injury induced by IL-6. Am J Physiol Lung Cell Mol Physiol. 2012 May 01; 302(9):L965-75. PMID: 22345573; PMCID: PMC3362159.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    9. Duan Y, Learoyd J, Meliton AY, Leff AR, Zhu X. Inhibition of Pyk2 blocks lung inflammation and injury in a mouse model of acute lung injury. Respir Res. 2012 Jan 18; 13:4. PMID: 22257498; PMCID: PMC3275485.
      Citations: 29     Fields:    Translation:Animals
    10. Li J, Beiser DG, Wang H, Das A, Berdyshev E, Li J, Leff AR, Stern SA, Vanden Hoek TL. Therapeutic hypothermia cardioprotection in murine hemorrhagic shock/resuscitation differentially affects p38a/p38?, Akt, and HspB1. J Trauma. 2011 Nov; 71(5):1262-70. PMID: 22071928.
      Citations: 7     Fields:    Translation:AnimalsCells
    11. Leff AR. The "other" airway. Proc Am Thorac Soc. 2011 Mar; 8(1):29. PMID: 21364217.
      Citations:    Fields:    Translation:Humans
    12. Wang L, Learoyd J, Duan Y, Leff AR, Zhu X. Hematopoietic Pyk2 regulates migration of differentiated HL-60 cells. J Inflamm (Lond). 2010 May 27; 7:26. PMID: 20507587; PMCID: PMC2892486.
      Citations: 9     
    13. Dudek SM, Desai A, Osan CM, Meliton AY, Leff AR, Muñoz NM. Group V phospholipase A2 mediates barrier disruption of human pulmonary endothelial cells caused by LPS in vitro. Am J Respir Cell Mol Biol. 2011 Mar; 44(3):361-8. PMID: 20448053; PMCID: PMC3095937.
      Citations: 16     Fields:    Translation:HumansCells
    14. Meliton AY, Meliton LN, Binder DC, Osan CM, Zhu X, Dudek SM, Leff AR, Muñoz NM. Cytosolic group IVa phospholipase A2 mediates IL-8/CXCL8-induced transmigration of human polymorphonuclear leukocytes in vitro. J Inflamm (Lond). 2010 Mar 18; 7:14. PMID: 20298597; PMCID: PMC2848033.
      Citations: 14     
    15. Brusasco V, Dinh-Xuan AT, Leff AR, Adler KB, Glenny RW, Dempsey JA, Levy ML, Panettieri R, Reddel HK, Singh D, Virchow JC. Impact factor and its role in academic promotion. Eur Respir J. 2009 Dec; 34(6):1499-500. PMID: 19948921.
      Citations: 1     Fields:    Translation:Humans
    16. Meliton AY, Osan CM, Meliton LN, Leff AR, Muñoz NM. Leukotriene D4 activates {beta}2-integrin adhesion in human polymorphonuclear leukocytes. Eur Respir J. 2010 Feb; 35(2):402-9. PMID: 19679609.
      Citations: 3     Fields:    Translation:HumansCells
    17. Leff AR. Impact factor and its role in academic promotion. Proc Am Thorac Soc. 2009 Aug 01; 6(4):337. PMID: 19675343.
      Citations:    Fields:    Translation:Humans
    18. Duan Y, Learoyd J, Meliton AY, Clay BS, Leff AR, Zhu X. Inhibition of Pyk2 blocks airway inflammation and hyperresponsiveness in a mouse model of asthma. Am J Respir Cell Mol Biol. 2010 Apr; 42(4):491-7. PMID: 19520918; PMCID: PMC2848740.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    19. Meliton AY, Meliton LN, Dudek SM, Leff AR, Muñoz NM. Secretory group V phospholipase A2 regulates acute lung injury and neutrophilic inflammation caused by LPS in mice. Am J Physiol Lung Cell Mol Physiol. 2009 Jun; 296(6):L879-87. PMID: 19286925; PMCID: PMC2692807.
      Citations: 28     Fields:    Translation:AnimalsCells
    20. Abraham E, Adler KB, Shapiro SD, Leff AR. The ATS journals' policy on image manipulation. Proc Am Thorac Soc. 2008 Dec 15; 5(9):869. PMID: 19056709.
      Citations: 1     Fields:    Translation:Humans
    21. Rennard SI, Higenbottam T, Leff AR. Foreword: "The Big Three". Proc Am Thorac Soc. 2008 Dec 01; 5(8):795. PMID: 19017731.
      Citations:    Fields:    Translation:Humans
    22. Abraham E, Adler KB, Shapiro SD, Leff AR. The ATS Journals' policy on image manipulation. Am J Respir Cell Mol Biol. 2008 Nov; 39(5):499. PMID: 18927351.
      Citations: 1     Fields:    
    23. Zhu X, Boetticher E, Wang L, Duan Y, Learoyd J, Leff AR. Proline-rich tyrosine kinase 2 regulates spreading and migration of eosinophils after beta2-integrin adhesion. Am J Respir Cell Mol Biol. 2008 Sep; 39(3):263-9. PMID: 18367725; PMCID: PMC2542445.
      Citations: 13     Fields:    Translation:HumansCells
    24. Leff AR, Muñoz NM. Future treatment to lessen exacerbations of chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2007 Dec; 4(8):659-66. PMID: 18073398.
      Citations: 1     Fields:    Translation:HumansCells
    25. Meliton AY, Munoz NM, Zhu X, Leff AR. Attenuated translocation of group IVa phospholipase A2 and up-regulated annexin-1 synthesis by glucocorticoid blocks beta 2-integrin adhesion in neutrophils. J Leukoc Biol. 2008 Feb; 83(2):344-51. PMID: 17971499.
      Citations: 7     Fields:    Translation:HumansCells
    26. Meliton AY, Arm JP, Bonventre JV, Cho W, Leff AR, Muñoz NM. Deletion of secretory group V phospholipase A2 attenuates cell migration and airway hyperresponsiveness in immunosensitized mice. J Immunol. 2007 Oct 01; 179(7):4800-7. PMID: 17878379.
      Citations: 41     Fields:    Translation:AnimalsCells
    27. Meliton AY, Munoz NM, Leff AR. Blockade of avidity and focal clustering of beta 2-integrin by cysteinyl leukotriene antagonism attenuates eosinophil adhesion. J Allergy Clin Immunol. 2007 Dec; 120(6):1316-23. PMID: 17904626.
      Citations: 6     Fields:    Translation:HumansCells
    28. Leff AR. Racemic = R enantiomer: a dual citation. Am J Respir Crit Care Med. 2007 Mar 15; 175(6):628; author reply 628-9. PMID: 17341650.
      Citations:    Fields:    Translation:HumansCells
    29. Zhao Y, He D, Zhao J, Wang L, Leff AR, Spannhake EW, Georas S, Natarajan V. Lysophosphatidic acid induces interleukin-13 (IL-13) receptor alpha2 expression and inhibits IL-13 signaling in primary human bronchial epithelial cells. J Biol Chem. 2007 Apr 06; 282(14):10172-9. PMID: 17287216; PMCID: PMC2659592.
      Citations: 24     Fields:    Translation:HumansCells
    30. Zhu X, Learoyd J, Butt S, Zhu L, Usatyuk PV, Natarajan V, Munoz NM, Leff AR. Regulation of eosinophil adhesion by lysophosphatidylcholine via a non-store-operated Ca2+ channel. Am J Respir Cell Mol Biol. 2007 May; 36(5):585-93. PMID: 17218614; PMCID: PMC1899330.
      Citations: 17     Fields:    Translation:HumansCells
    31. Meliton AY, Lambertino A, Boetticher E, Learoyd J, Sultan F, Zhu X, Cho W, Leff AR, Muñoz NM. Transcellular secretion of group V phospholipase A2 from epithelium induces beta 2-integrin-mediated adhesion and synthesis of leukotriene C4 in eosinophils. J Immunol. 2006 Jul 01; 177(1):574-82. PMID: 16785555.
      Citations: 14     Fields:    Translation:HumansCells
    32. Meliton AY, Lambertino A, Boetticher E, Learoyd J, Zhu X, Leff AR, Muñoz NM. Phosphodiesterase 4 inhibition of beta2-integrin adhesion caused by leukotriene B4 and TNF-alpha in human neutrophils. Eur Respir J. 2006 Nov; 28(5):920-8. PMID: 16807266.
      Citations: 7     Fields:    Translation:HumansCells
    33. Munoz NM, Leff AR. Highly purified selective isolation of eosinophils from human peripheral blood by negative immunomagnetic selection. Nat Protoc. 2006; 1(6):2613-20. PMID: 17406516.
      Citations: 19     Fields:    Translation:HumansCells
    34. Abraham E, Shapiro SD, Leff AR. The NIH Public Access Policy and ATS journals. Am J Respir Crit Care Med. 2005 Apr 01; 171(7):671-2. PMID: 15790862.
      Citations:    Fields:    Translation:Humans
    35. Sano M, Leff AR, Myou S, Boetticher E, Meliton AY, Learoyd J, Lambertino AT, Munoz NM, Zhu X. Regulation of interleukin-5-induced beta2-integrin adhesion of human eosinophils by phosphoinositide 3-kinase. Am J Respir Cell Mol Biol. 2005 Jul; 33(1):65-70. PMID: 15802551; PMCID: PMC2715304.
      Citations: 23     Fields:    Translation:HumansCells
    36. Liu J, Zhu X, Myo S, Lambertino AT, Xu C, Boetticher E, Sano M, Cordoba M, Learoyd J, Meliton A, Johnson M, Leff AR, Muñoz NM. Glucocorticoid-induced surface expression of annexin 1 blocks beta2-integrin adhesion of human eosinophils to intercellular adhesion molecule 1 surrogate protein. J Allergy Clin Immunol. 2005 Mar; 115(3):493-500. PMID: 15753895.
      Citations: 4     Fields:    Translation:HumansCells
    37. Abraham E, Shapiro SD, Leff AR. The NIH Public Access Policy and ATS journals. Proc Am Thorac Soc. 2005; 2(1):1-2. PMID: 16113460.
      Citations:    Fields:    
    38. Leff AR, Shapiro SD, Abraham E. The unintended consequences of noble intentions to inform. Proc Am Thorac Soc. 2005; 2(1):2-3. PMID: 16113461.
      Citations:    Fields:    
    39. Cox PG, Miller J, Mitzner W, Leff AR. Radiofrequency ablation of airway smooth muscle for sustained treatment of asthma: preliminary investigations. Eur Respir J. 2004 Oct; 24(4):659-63. PMID: 15459147.
      Citations: 37     Fields:    Translation:HumansAnimals
    40. Bates J, Irvin C, Brusasco V, Drazen J, Fredberg J, Loring S, Eidelman D, Ludwig M, Macklem P, Martin J, Milic-Emili J, Hantos Z, Hyatt R, Lai-Fook S, Leff A, Solway J, Lutchen K, Suki B, Mitzner W, Pride N, Sly P, Paré P. The use and misuse of Penh in animal models of lung disease. Am J Respir Cell Mol Biol. 2004 Sep; 31(3):373-4. PMID: 15317683.
      Citations: 72     Fields:    Translation:Animals
    41. Danek CJ, Lombard CM, Dungworth DL, Cox PG, Miller JD, Biggs MJ, Keast TM, Loomas BE, Wizeman WJ, Hogg JC, Leff AR. Reduction in airway hyperresponsiveness to methacholine by the application of RF energy in dogs. J Appl Physiol (1985). 2004 Nov; 97(5):1946-53. PMID: 15258133.
      Citations: 39     Fields:    Translation:Animals
    42. Myo S, Zhu X, Myou S, Meliton AY, Liu J, Boetticher E, Lambertino AT, Xu C, Leff AR, Muñoz NM. Additive blockade of beta 2-integrin adhesion of eosinophils by salmeterol and fluticasone propionate. Eur Respir J. 2004 Apr; 23(4):511-7. PMID: 15083746.
      Citations: 2     Fields:    Translation:HumansCells
    43. Liu J, Meliton AY, Zhu X, Lambertino AT, Xu C, Myo S, Myou S, Boetticher E, Johnson M, Leff AR, Muñoz NM. Beta2-integrin adhesion caused by eotaxin but not IL-5 is blocked by PDE-4 inhibition and beta2-adrenoceptor activation in human eosinophils. Pulm Pharmacol Ther. 2004; 17(2):73-9. PMID: 15123228.
      Citations: 3     Fields:    Translation:HumansCells
    44. Myou S, Leff AR, Myo S, Boetticher E, Tong J, Meliton AY, Liu J, Munoz NM, Zhu X. Blockade of inflammation and airway hyperresponsiveness in immune-sensitized mice by dominant-negative phosphoinositide 3-kinase-TAT. J Exp Med. 2003 Nov 17; 198(10):1573-82. PMID: 14623911; PMCID: PMC2194122.
      Citations: 102     Fields:    Translation:Animals
    45. Zhu X, Lambertino AT, Houghton TJ, McGilvra JD, Xu C, Rawal VH, Leff AR. Structural determinants of blockade of eosinophil activation, adhesion and secretion by synthetic analogs of phomactin. Life Sci. 2003 Oct 24; 73(23):3005-16. PMID: 14519449.
      Citations: 5     Fields:    Translation:HumansCells
    46. Myou S, Zhu X, Myo S, Boetticher E, Meliton AY, Liu J, Munoz NM, Leff AR. Blockade of airway inflammation and hyperresponsiveness by HIV-TAT-dominant negative Ras. J Immunol. 2003 Oct 15; 171(8):4379-84. PMID: 14530363.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    47. Myou S, Leff AR, Myo S, Boetticher E, Meliton AY, Lambertino AT, Liu J, Xu C, Munoz NM, Zhu X. Activation of group IV cytosolic phospholipase A2 in human eosinophils by phosphoinositide 3-kinase through a mitogen-activated protein kinase-independent pathway. J Immunol. 2003 Oct 15; 171(8):4399-405. PMID: 14530366.
      Citations: 12     Fields:    Translation:HumansCells
    48. Meliton AY, Liu J, Lambertino AT, Boetticher E, Myo S, Myou S, Zhu X, Johnson M, Leff AR, Muñoz NM. Blockade of LTC4 synthesis caused by additive inhibition of gIV-PLA2 phosphorylation: Effect of salmeterol and PDE4 inhibition in human eosinophils. J Allergy Clin Immunol. 2003 Aug; 112(2):404-10. PMID: 12897749.
      Citations: 2     Fields:    Translation:HumansCells
    49. Kim YJ, Meliton AY, Kim KP, Han SK, Boetticher E, O'Leary E, Myou S, Zhu X, Bonventre JV, Leff AR, Cho W, Muñoz NM. Human group V phospholipase A2 induces group IVA phospholipase A2-independent cysteinyl leukotriene synthesis in human eosinophils. J Biol Chem. 2003 Oct 03; 278(40):38813-20. PMID: 12796497.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    50. Noth I, Strek ME, Leff AR. Churg-Strauss syndrome. Lancet. 2003 Feb 15; 361(9357):587-94. PMID: 12598156.
      Citations: 96     Fields:    Translation:Humans
    51. Zhu X, Jacobs B, Boetticher E, Myou S, Meliton A, Sano H, Lambertino AT, Leff AR, Muñoz NM. IL-5-induced integrin adhesion of human eosinophils caused by ERK1/2-mediated activation of cPLA2. J Leukoc Biol. 2002 Nov; 72(5):1046-53. PMID: 12429728.
      Citations: 14     Fields:    Translation:HumansCells
    52. Myou S, Zhu X, Boetticher E, Myo S, Meliton A, Lambertino A, Munoz NM, Leff AR. Blockade of focal clustering and active conformation in beta 2-integrin-mediated adhesion of eosinophils to intercellular adhesion molecule-1 caused by transduction of HIV TAT-dominant negative Ras. J Immunol. 2002 Sep 01; 169(5):2670-6. PMID: 12193740.
      Citations: 13     Fields:    Translation:HumansCells
    53. Myou S, Zhu X, Boetticher E, Qin Y, Myo S, Meliton A, Lambertino A, Munoz NM, Hamann KJ, Leff AR. Regulation of adhesion of AML14.3D10 cells by surface clustering of beta2-integrin caused by ERK-independent activation of cPLA2. Immunology. 2002 Sep; 107(1):77-85. PMID: 12225365; PMCID: PMC1782764.
      Citations: 4     Fields:    Translation:HumansCells
    54. Kim YJ, Kim KP, Han SK, Munoz NM, Zhu X, Sano H, Leff AR, Cho W. Group V phospholipase A2 induces leukotriene biosynthesis in human neutrophils through the activation of group IVA phospholipase A2. J Biol Chem. 2002 Sep 27; 277(39):36479-88. PMID: 12124392.
      Citations: 24     Fields:    Translation:HumansCells
    55. Schmidt DT, Dent G, Leff AR, Rabe KF, Rühlmann E, Muñoz NM. Studying human airway pharmacology in microsections: application of videomicrometry. Eur Respir J. 2002 Jun; 19(6):991-6. PMID: 12108884.
      Citations: 4     Fields:    Translation:HumansCells
    56. Boetticher E, Sperling AI, Kim KP, Meliton AY, Zhu X, Lambertino A, Cho W, Leff AR, Muñoz NM. Quantitation of secretory group V phospholipase A(2) in human tissues by sandwich enzyme-linked immunosorbent assay. J Immunol Methods. 2002 Apr 01; 262(1-2):41-51. PMID: 11983218.
      Citations: 1     Fields:    Translation:HumansCells
    57. Sano A, Zhu X, Sano H, Boetticher E, Leff AR, Muñoz NM. Regulation of eosinophil function by phosphatidylinositol-specific PLC and cytosolic PLA(2). Am J Physiol Lung Cell Mol Physiol. 2001 Oct; 281(4):L844-51. PMID: 11557588.
      Citations: 4     Fields:    Translation:HumansCells
    58. Zhu X, Sano H, Kim KP, Sano A, Boetticher E, Cho W, Leff AR, Muñoz NM. Role of mitogen-activated protein kinase-mediated cytosolic phospholipase A2 activation in arachidonic acid metabolism in human eosinophils. J Immunol. 2001 Jul 01; 167(1):461-8. PMID: 11418683.
      Citations: 9     Fields:    Translation:HumansCells
    59. Leff AR. The Antileukotriene Working Group consensus conference overview. Ann Allergy Asthma Immunol. 2001 Jun; 86(6 Suppl 1):1-3. PMID: 11426911.
      Citations:    Fields:    Translation:Humans
    60. Leff AR, Antileukotriene Working Group. Discovery of leukotrienes and development of antileukotriene agents. Ann Allergy Asthma Immunol. 2001 Jun; 86(6 Suppl 1):4-8. PMID: 11426915.
      Citations: 6     Fields:    Translation:HumansAnimals
    61. Sano H, Zhu X, Sano A, Boetticher EE, Shioya T, Jacobs B, Munoz NM, Leff AR. Extracellular signal-regulated kinase 1/2-mediated phosphorylation of cytosolic phospholipase A2 is essential for human eosinophil adhesion to fibronectin. J Immunol. 2001 Mar 01; 166(5):3515-21. PMID: 11207311.
      Citations: 11     Fields:    Translation:HumansCells
    62. Myou S, Sano H, Fujimura M, Zhu X, Kurashima K, Kita T, Nakao S, Nonomura A, Shioya T, Kim KP, Munoz NM, Cho W, Leff AR. Blockade of eosinophil migration and airway hyperresponsiveness by cPLA2-inhibition. Nat Immunol. 2001 Feb; 2(2):145-9. PMID: 11175812.
      Citations: 19     Fields:    Translation:AnimalsCells
    63. Leff AR. Regulation of leukotrienes in the management of asthma: biology and clinical therapy. Annu Rev Med. 2001; 52:1-14. PMID: 11160764.
      Citations: 13     Fields:    Translation:Humans
    64. Kim KP, Rafter JD, Bittova L, Han SK, Snitko Y, Munoz NM, Leff AR, Cho W. Mechanism of human group V phospholipase A2 (PLA2)-induced leukotriene biosynthesis in human neutrophils. A potential role of heparan sulfate binding in PLA2 internalization and degradation. J Biol Chem. 2001 Apr 06; 276(14):11126-34. PMID: 11118430.
      Citations: 22     Fields:    Translation:HumansCells
    65. Leff AR. Role of leukotrienes in bronchial hyperresponsiveness and cellular responses in airways. Thorax. 2000 Oct; 55 Suppl 2:S32-7. PMID: 10992554; PMCID: PMC1765960.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    66. Zhu X, Subbaraman R, Sano H, Jacobs B, Sano A, Boetticher E, Leff AR, Muñoz NM. A surrogate method for assessment of beta(2)-integrin-dependent adhesion of human eosinophils to ICAM-1. J Immunol Methods. 2000 Jun 23; 240(1-2):157-64. PMID: 10854610.
      Citations: 17     Fields:    Translation:HumansCells
    67. van Seventer GA, Semnani RT, Leff AR, Muñoz NM. Augmentation of LTC(4) synthesis in human eosinophils caused by CD3-stimulated Th2-like cells in vitro. Am J Physiol Lung Cell Mol Physiol. 2000 Jun; 278(6):L1172-9. PMID: 10835322.
      Citations: 1     Fields:    Translation:HumansCells
    68. Munoz NM, Zhu X, Magnussen H, Leff AR, Rabe KF, Dent G, Rühlmann E. Involvement of protein tyrosine kinases in activation of human eosinophils by platelet-activating factor. Immunology. 2000 Jun; 100(2):231-7. PMID: 10886400; PMCID: PMC2327005.
      Citations: 5     Fields:    Translation:HumansCells
    69. Kim KP, Han SK, Boetticher E, Sperling AI, Sano H, Zhu X, Cho W, Leff AR, Muñoz NM. Characterization of monoclonal antibodies specific for 14-kDa human group V secretory phospholipase A2 (hVPLA2). Hybridoma. 2000 Apr; 19(2):171-6. PMID: 10868798.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    70. Douglas IS, Leff AR, Sperling AI. CD4+ T cell and eosinophil adhesion is mediated by specific ICAM-3 ligation and results in eosinophil activation. J Immunol. 2000 Mar 15; 164(6):3385-91. PMID: 10706734.
      Citations: 4     Fields:    Translation:HumansCells
    71. Leff AR. Role of leukotrienes in bronchial hyperresponsiveness and cellular responses in airways. Am J Respir Crit Care Med. 2000 Feb; 161(2 Pt 2):S125-32. PMID: 10673241.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    72. Ndukwu IM, Naureckas ET, Maxwell C, Waldman M, Leff AR. Relationship of cellular transmigration and airway response after allergen challenge. Am J Respir Crit Care Med. 1999 Nov; 160(5 Pt 1):1516-24. PMID: 10556114.
      Citations: 5     Fields:    Translation:HumansCells
    73. Hamann KJ, Rabe KF, Sano H, Zhu X, Leff AR, Muñoz NM. Augmentation of eosinophil degranulation and LTC(4) secretion by integrin-mediated endothelial cell adhesion. Am J Physiol. 1999 10; 277(4):L802-10. PMID: 10516222.
      Citations: 4     Fields:    Translation:HumansCells
    74. Zhu X, Kim KP, Sano H, Cho W, Leff AR, Muñoz NM. Cytosolic phospholipase A2 activation is essential for beta 1 and beta 2 integrin-dependent adhesion of human eosinophils. J Immunol. 1999 Sep 15; 163(6):3423-9. PMID: 10477614.
      Citations: 17     Fields:    Translation:HumansCells
    75. Sano A, Sano H, Choi J, Zhu X, Jacobs B, Leff AR, Muñoz NM. Inhibition of cPLA2 translocation and leukotriene C4 secretion by fluticasone propionate in exogenously activated human eosinophils. Am J Respir Crit Care Med. 1999 Jun; 159(6):1903-9. PMID: 10351938.
      Citations: 6     Fields:    Translation:HumansCells
    76. Carson SS, Bach PB, Brzozowski L, Leff A. Outcomes after long-term acute care. An analysis of 133 mechanically ventilated patients. Am J Respir Crit Care Med. 1999 May; 159(5 Pt 1):1568-73. PMID: 10228128.
      Citations: 69     Fields:    Translation:Humans
    77. Han SK, Kim KP, Koduri R, Bittova L, Munoz NM, Leff AR, Wilton DC, Gelb MH, Cho W. Roles of Trp31 in high membrane binding and proinflammatory activity of human group V phospholipase A2. J Biol Chem. 1999 Apr 23; 274(17):11881-8. PMID: 10207008.
      Citations: 34     Fields:    Translation:HumansCells
    78. Sano H, Sano A, Zhu X, Herrnreiter A, Choi J, Leff AR, Muñoz NM. Upregulated surface expression of intracellularly sequestered Igepsilon receptors (FcepsilonRII/CD23) following activation in human peripheral blood eosinophils. Proc Assoc Am Physicians. 1999 Jan-Feb; 111(1):82-91. PMID: 9893160.
      Citations: 1     Fields:    Translation:HumansCells
    79. Bach PB, Carson SS, Leff A. Outcomes and resource utilization for patients with prolonged critical illness managed by university-based or community-based subspecialists. Am J Respir Crit Care Med. 1998 Nov; 158(5 Pt 1):1410-5. PMID: 9817687.
      Citations: 9     Fields:    Translation:Humans
    80. Leff AR. Biology of airway smooth muscle. Conference summary. Am J Respir Crit Care Med. 1998 Nov; 158(5 Pt 3):S78-9. PMID: 9817729.
      Citations:    Fields:    Translation:HumansAnimals
    81. Zhu X, Hamann KJ, Rubio N, Mayer D, Hernrreiter A, Leff AR, Muñoz NM. Intracellular expression of Fc gamma RIII (CD16) and its mobilization by chemoattractants in human eosinophils. J Immunol. 1998 Sep 01; 161(5):2574-9. PMID: 9725258.
      Citations: 6     Fields:    Translation:HumansCells
    82. Mitchell RW, Cozzi P, Ndukwu IM, Spaethe S, Leff AR, Padrid PA. Differential effects of cyclosporine A after acute antigen challenge in sensitized cats in vivo and ex vivo. Br J Pharmacol. 1998 Mar; 123(6):1198-204. PMID: 9559905; PMCID: PMC1565269.
      Citations: 4     Fields:    Translation:AnimalsCells
    83. White SR, Tenor H, Bodtke K, Schudt C, Leff AR, Magnussen H, Rabe KF, Dent G. Cyclic nucleotide phosphodiesterase in human bronchial epithelial cells: characterization of isoenzymes and functional effects of PDE inhibitors. Pulm Pharmacol Ther. 1998 Feb; 11(1):47-56. PMID: 9802963.
      Citations: 16     Fields:    Translation:HumansCells
    84. Leff AR. Pharmacologic management of asthma. J Allergy Clin Immunol. 1998 Feb; 101(2 Pt 2):S397-9. PMID: 9500737.
      Citations:    Fields:    Translation:Humans
    85. Zhu X, Leff AR, Magnussen H, Rabe KF, Dent G, Muñoz NM, Rühlmann E. Protein kinase C inhibition enhances platelet-activating factor-induced eicosanoid production in human eosinophils. Am J Respir Cell Mol Biol. 1998 Jan; 18(1):136-44. PMID: 9448055.
      Citations: 4     Fields:    Translation:HumansCells
    86. Garland A, Necheles J, White SR, Neeley SP, Leff AR, Carson SS, Alger LE, McAllister K, Solway J. Activated eosinophils elicit substance P release from cultured dorsal root ganglion neurons. Am J Physiol. 1997 11; 273(5):L1096-102. PMID: 9374740.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    87. Leff DR, Leff AR. Tuberculosis control policies in major metropolitan health departments in the United States. VI. Standard of practice in 1996. Am J Respir Crit Care Med. 1997 Nov; 156(5):1487-94. PMID: 9372665.
      Citations: 3     Fields:    Translation:Humans
    88. Leff A. Dose-response relationships in determining the safety:efficacy ratio. Respir Med. 1997 Nov; 91 Suppl A:34-7. PMID: 9474367.
      Citations:    Fields:    Translation:Humans
    89. Mitchell RW, Rabe KF, Magnussen H, Leff AR. Passive sensitization of human airways induces myogenic contractile responses in vitro. J Appl Physiol (1985). 1997 Oct; 83(4):1276-81. PMID: 9338437.
      Citations: 7     Fields:    Translation:HumansCells
    90. Heuertz RM, Hamann KJ, Hershenson MB, Leff AR. Adhesion of bovine airway smooth muscle cells activates extracellular signal-regulated kinases. Am J Respir Cell Mol Biol. 1997 Oct; 17(4):456-61. PMID: 9376120.
      Citations: 3     Fields:    Translation:AnimalsCells
    91. Palmer JS, Cromie WJ, Plzak LF, Leff AR. A platelet activating factor antagonist attenuates the effects of testicular ischemia. J Urol. 1997 Sep; 158(3 Pt 2):1186-90. PMID: 9258168.
      Citations: 5     Fields:    Translation:Animals
    92. Ndukwu IM, White SR, Leff AR, Mitchell RW. EP1 receptor blockade attenuates both spontaneous tone and PGE2-elicited contraction in guinea pig trachealis. Am J Physiol. 1997 Sep; 273(3 Pt 1):L626-33. PMID: 9316498.
      Citations: 7     Fields:    Translation:Animals
    93. Saito M, Sato R, Herrnreiter A, Oyaizu M, Kasugai H, Narahashi T, Leff AR, Muñoz NM. Association of granular exocytosis with Ca(2+)-activated K+ channels in human eosinophils. Am J Physiol. 1997 Jul; 273(1 Pt 1):L16-21. PMID: 9252535.
      Citations: 4     Fields:    Translation:HumansCells
    94. Mitchell RW, Ndukwu IM, Leff AR, Padrid PA. Muscarinic hyperresponsiveness of antigen-sensitized feline airway smooth muscle in vitro. Am J Vet Res. 1997 Jun; 58(6):672-6. PMID: 9185978.
      Citations: 1     Fields:    Translation:Animals
    95. Douglas I, Mayer D, Herrnreiter A, Zhu X, Leff AR, Muñoz NM. Eosinophil chemotaxis inhibited by 5-lipoxygenase blockade and leukotriene receptor antagonism. Am J Respir Crit Care Med. 1997 Apr; 155(4):1398-403. PMID: 9105085.
      Citations: 11     Fields:    Translation:AnimalsCells
    96. Mitchell RW, Magnussen H, Leff AR, Rabe KF, Rühlmann E, Muñoz NM. Conservation of bronchiolar wall area during constriction and dilation of human airways. J Appl Physiol (1985). 1997 Mar; 82(3):954-8. PMID: 9074987.
      Citations: 1     Fields:    Translation:Humans
    97. Leff AR. Future directions in asthma therapy. Is a cure possible? Chest. 1997 Feb; 111(2 Suppl):61S-68S. PMID: 9042028.
      Citations: 2     Fields:    Translation:Humans
    98. Leff AR, Herrnreiter A, Naclerio RM, Baroody FM, Handley DA, Muñoz NM. Effect of enantiomeric forms of albuterol on stimulated secretion of granular protein from human eosinophils. Pulm Pharmacol Ther. 1997; 10(2):97-104. PMID: 9425641.
      Citations: 8     Fields:    Translation:HumansCells
    99. Zhu X, Rubio N, Herrnreiter A, Mayer D, Douglas I, Leff AR, Muñoz NM. Quantitation of the cytosolic phospholipase A2 (type IV) in isolated human peripheral blood eosinophils by sandwich-ELISA. J Immunol Methods. 1996 Dec 15; 199(2):119-26. PMID: 8982353.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    100. Padrid PA, Cozzi P, Leff AR. Cyclosporine A inhibits airway reactivity and remodeling after chronic antigen challenge in cats. Am J Respir Crit Care Med. 1996 Dec; 154(6 Pt 1):1812-8. PMID: 8970375.
      Citations: 9     Fields:    Translation:AnimalsCellsPHPublic Health
    101. Leff AR. Identifying patients at risk from the use of beta-adrenergic agonists. Am J Respir Crit Care Med. 1996 Dec; 154(6 Pt 1):1593. PMID: 8970339.
      Citations: 1     Fields:    Translation:Humans
    102. Hamann KJ, Neeley SP, Dowling TL, Grant JA, Leff AR. Effect of interleukin-5 exposure during in vitro eosinophilopiesis on MAC-1 adhesion molecule expression and function on cultured human eosinophils. Blood. 1996 Nov 01; 88(9):3575-82. PMID: 8896426.
      Citations:    Fields:    Translation:HumansCells
    103. Rabe KF, Neeley SP, Herrnreiter A, Zhu X, McAllister K, Mayer D, Magnussen H, Galens S, Leff AR, Muñoz NM. Eosinophil VLA-4 binding to fibronectin augments bronchial narrowing through 5-lipoxygenase activation. Am J Physiol. 1996 Apr; 270(4 Pt 1):L587-94. PMID: 8928818.
      Citations: 3     Fields:    Translation:HumansCells
    104. Strek ME, Williams FS, Gleich GJ, Leff AR, White SR. Mechanisms of smooth muscle contraction elicited by cationic proteins in guinea pig trachealis. Am J Physiol. 1996 Jan; 270(1 Pt 1):L133-40. PMID: 8772536.
      Citations: 3     Fields:    Translation:Animals
    105. Mitchell RW, Ndukwu IM, Herrnreiter A, Uzendoski K, Gitter B, Solway J, Leff AR. Differential tachykinin receptor subtype activation in capsaicin and KCl contractions of guinea pig trachealis. Am J Physiol. 1995 Dec; 269(6 Pt 1):L837-42. PMID: 8572245.
      Citations: 2     Fields:    Translation:Animals
    106. Cozzi PJ, Padrid P, Tompkins MB, Alegre ML, Takeda J, Leff AR. Bioactivity of recombinant feline interleukin-2 on human and feline leukocytes. Vet Immunol Immunopathol. 1995 Sep; 48(1-2):27-33. PMID: 8533314.
      Citations:    Fields:    Translation:HumansAnimalsCells
    107. Leff AR. The cost of our good intentions. Am J Respir Crit Care Med. 1995 Sep; 152(3):837. PMID: 7663794.
      Citations:    Fields:    Translation:Humans
    108. Rabe KF, Vita AJ, McAllister K, Mayer D, Weiss M, Leff AR, Muñoz NM. Paradoxical blockade of beta adrenergically mediated inhibition of stimulated eosinophil secretion by salmeterol. J Pharmacol Exp Ther. 1995 May; 273(2):850-4. PMID: 7752089.
      Citations: 5     Fields:    Translation:HumansCells
    109. Hamann KJ, Dowling TL, Neeley SP, Grant JA, Leff AR. Hyaluronic acid enhances cell proliferation during eosinopoiesis through the CD44 surface antigen. J Immunol. 1995 Apr 15; 154(8):4073-80. PMID: 7535820.
      Citations: 21     Fields:    Translation:HumansCells
    110. Munoz NM, Leff AR. New method for real-time measurements of changes in lumenal area of microsection explants of airways by videomicrometry. Chest. 1995 Mar; 107(3 Suppl):146S-147S. PMID: 7875000.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    111. Leff AR, Muñoz NM. Blockade of eosinophil migration by 5-lipoxygenase and cyclooxygenase inhibition in explanted guinea pig trachealis. Am J Physiol. 1995 Mar; 268(3 Pt 1):L446-54. PMID: 7900826.
      Citations: 3     Fields:    Translation:AnimalsCells
    112. Galens S, Rabe KF, Herrnreiter A, Mayer D, Morton B, McAllister K, Leff AR, Muñoz NM. Assessment of agonist- and cell-mediated responses in airway microsections by computerized videomicrometry. Am J Physiol. 1995 Mar; 268(3 Pt 1):L519-25. PMID: 7900832.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    113. Padrid P, Snook S, Finucane T, Shiue P, Cozzi P, Solway J, Leff AR. Persistent airway hyperresponsiveness and histologic alterations after chronic antigen challenge in cats. Am J Respir Crit Care Med. 1995 Jan; 151(1):184-93. PMID: 7812551.
      Citations: 46     Fields:    Translation:AnimalsCellsPHPublic Health
    114. Padrid PA, Mitchell RW, Ndukwu IM, Spaethe S, Shiue P, Cozzi P, Leff AR, Shiou P [corrected to Shiue P]. Cyproheptadine-induced attenuation of type-I immediate-hypersensitivity reactions of airway smooth muscle from immune-sensitized cats. Am J Vet Res. 1995 Jan; 56(1):109-15. PMID: 7695137.
      Citations: 1     Fields:    Translation:Animals
    115. Leff AR. Inflammatory mediation of airway hyperresponsiveness by peripheral blood granulocytes. The case for the eosinophil. Chest. 1994 Oct; 106(4):1202-8. PMID: 7924496.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    116. Vita AJ, Morton BE, Magnussen H, Leff AR, Rabe KF, Muñoz NM. Contraction of human bronchial smooth muscle caused by activated human eosinophils. Am J Physiol. 1994 Sep; 267(3 Pt 1):L326-34. PMID: 7943259.
      Citations: 6     Fields:    Translation:HumansCells
    117. Leff AR. Your kinda journal. Am J Respir Crit Care Med. 1994 Sep; 150(3):606. PMID: 8087323.
      Citations:    Fields:    
    118. Sanghavi JN, Rabe KF, Kim JS, Magnussen H, Leff AR, White SR. Migration of human and guinea pig airway epithelial cells in response to calcitonin gene-related peptide. Am J Respir Cell Mol Biol. 1994 Aug; 11(2):181-7. PMID: 8049078.
      Citations: 6     Fields:    Translation:AnimalsCells
    119. Neeley SP, Hamann KJ, Dowling TL, McAllister KT, White SR, Leff AR. Augmentation of stimulated eosinophil degranulation by VLA-4 (CD49d)-mediated adhesion to fibronectin. Am J Respir Cell Mol Biol. 1994 Aug; 11(2):206-13. PMID: 8049081.
      Citations: 5     Fields:    Translation:HumansCells
    120. Mitchell RW, Magnussen H, Leff AR, Rabe KF, Rühlmann E. Passive sensitization of human bronchi augments smooth muscle shortening velocity and capacity. Am J Physiol. 1994 Aug; 267(2 Pt 1):L218-22. PMID: 8074246.
      Citations: 26     Fields:    Translation:Humans
    121. Ndukwu IM, Solway J, Arbetter K, Uzendoski K, Leff AR, Mitchell RW. Immune sensitization augments epithelium-dependent spontaneous tone in guinea pig trachealis. Am J Physiol. 1994 May; 266(5 Pt 1):L485-92. PMID: 8203543.
      Citations: 2     Fields:    Translation:AnimalsPHPublic Health
    122. Murphy TM, Ray DW, Alger LE, Phillips IJ, Roach JC, Leff AR, Solway J. Ontogeny of dry gas hyperpnea-induced bronchoconstriction in guinea pigs. J Appl Physiol (1985). 1994 Mar; 76(3):1150-5. PMID: 8005858.
      Citations: 2     Fields:    Translation:AnimalsCells
    123. Munoz NM, Vita AJ, Neeley SP, McAllister K, Spaethe SM, White SR, Leff AR. Beta adrenergic modulation of formyl-methionine-leucine-phenylalanine-stimulated secretion of eosinophil peroxidase and leukotriene C4. J Pharmacol Exp Ther. 1994 Jan; 268(1):139-43. PMID: 8301549.
      Citations: 11     Fields:    Translation:HumansCells
    124. Mitchell RW, Ndukwu IM, Arbetter K, Solway J, Leff AR. Effect of airway inflammation on smooth muscle shortening and contractility in guinea pig trachealis. Am J Physiol. 1993 Dec; 265(6 Pt 1):L549-54. PMID: 8279571.
      Citations: 4     Fields:    Translation:Animals
    125. Leff DR, Leff AR. Tuberculosis control policies in major metropolitan health departments in the United States. V. Standard of practice in 1992. Am Rev Respir Dis. 1993 Dec; 148(6 Pt 1):1530-6. PMID: 8256895.
      Citations:    Fields:    Translation:Humans
    126. Hamann KJ, Strek ME, Baranowski SL, Munoz NM, Williams FS, White SR, Vita A, Leff AR. Effects of activated eosinophils cultured from human umbilical cord blood on guinea pig trachealis. Am J Physiol. 1993 Sep; 265(3 Pt 1):L301-7. PMID: 8214090.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    127. Ferguson MK, Williams UE, Leff AR, Mitchell RW. Heterogeneity of tracheobronchial lymphatic smooth muscle responses to histamine and 5-hydroxytryptamine. Lymphology. 1993 Sep; 26(3):113-9. PMID: 8258984.
      Citations: 1     Fields:    Translation:Animals
    128. Cozzi PJ, Padrid PA, Takeda J, Alegre ML, Yuhki N, Leff AR. Sequence and functional characterization of feline interleukin 2. Biochem Biophys Res Commun. 1993 Aug 16; 194(3):1038-43. PMID: 8352761.
      Citations: 2     Fields:    Translation:AnimalsCells
    129. Hsiue TR, Leff AR, Garland A, Hershenson MB, Ray DW, Solway J. Impaired sensorineural function after allergen-induced mediator release. Am Rev Respir Dis. 1993 Aug; 148(2):447-54. PMID: 7688201.
      Citations: 2     Fields:    Translation:AnimalsCells
    130. Solway J, Kao BM, Jordan JE, Gitter B, Rodger IW, Howbert JJ, Alger LE, Necheles J, Leff AR, Garland A. Tachykinin receptor antagonists inhibit hyperpnea-induced bronchoconstriction in guinea pigs. J Clin Invest. 1993 Jul; 92(1):315-23. PMID: 8392088; PMCID: PMC293598.
      Citations: 3     Fields:    Translation:Animals
    131. Mitchell RW, Ndukuw IM, Ikeda K, Arbetter K, Leff AR. Effect of immune sensitization on stimulated ACh release from trachealis muscle in vitro. Am J Physiol. 1993 Jul; 265(1 Pt 1):L13-8. PMID: 8338177.
      Citations: 3     Fields:    Translation:AnimalsPHPublic Health
    132. Padrid P, Wolf R, Munoz NM, Spaethe S, Finucane T, Solway J, Leff AR. Augmented muscarinic responsiveness caused by 5-lipoxygenase products secreted from alveolar macrophages in isolated-perfused rat lung. Am Rev Respir Dis. 1993 Jun; 147(6 Pt 1):1514-20. PMID: 8503563.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    133. Strek ME, White SR, Ndukwu IM, Munoz NM, Williams FS, Vita AJ, Leff AR, Mitchell RW. Physiologic significance of epithelial removal on guinea pig tracheal smooth muscle response to acetylcholine and serotonin. Am Rev Respir Dis. 1993 Jun; 147(6 Pt 1):1477-82. PMID: 8503558.
      Citations: 1     Fields:    Translation:Animals
    134. Neeley SP, Hamann KJ, White SR, Baranowski SL, Burch RA, Leff AR. Selective regulation of expression of surface adhesion molecules Mac-1, L-selectin, and VLA-4 on human eosinophils and neutrophils. Am J Respir Cell Mol Biol. 1993 Jun; 8(6):633-9. PMID: 7686761.
      Citations: 12     Fields:    Translation:HumansCells
    135. White SR, Strek ME, Kulp GV, Spaethe SM, Burch RA, Neeley SP, Leff AR. Regulation of human eosinophil degranulation and activation by endogenous phospholipase A2. J Clin Invest. 1993 May; 91(5):2118-25. PMID: 8387540; PMCID: PMC288212.
      Citations: 9     Fields:    Translation:Cells
    136. Strek ME, White SR, Hsiue TR, Kulp GV, Williams FS, Leff AR. Effect of mode of activation of human eosinophils on tracheal smooth muscle contraction in guinea pigs. Am J Physiol. 1993 May; 264(5 Pt 1):L475-81. PMID: 8498524.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    137. Barron WM, Leff AR. Asthma in pregnancy. Am Rev Respir Dis. 1993 Mar; 147(3):510-1. PMID: 8442579.
      Citations: 1     Fields:    Translation:Humans
    138. Munoz NM, Hamann KJ, Vita A, Cozzi PJ, Baranowski S, Solway J, Leff AR. Activation of tracheal smooth muscle responsiveness by fMLP-treated HL-60 cells and neutrophils. Am J Physiol. 1993 Mar; 264(3 Pt 1):L222-8. PMID: 8460711.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    139. Ferguson MK, Williams U, Leff AR, Mitchell RW. Length-tension characteristics of bovine tracheobronchial lymphatic smooth muscle. Lymphology. 1993 Mar; 26(1):19-24. PMID: 8464221.
      Citations: 2     Fields:    Translation:Animals
    140. Munoz NM, Zak R, Panettieri RA, Wiesner R, Leff AR. Changes in levels of mRNA encoding myosin heavy chain in porcine trachealis during ontogenesis. Am J Respir Cell Mol Biol. 1993 Mar; 8(3):252-7. PMID: 8448016.
      Citations: 1     Fields:    Translation:AnimalsCells
    141. Mitchell RW, Koenig SM, Popovich KJ, Kelly E, Tallet J, Leff AR. Pertussis toxin augments beta-adrenergic relaxation of muscarinic contraction in canine trachealis. Am Rev Respir Dis. 1993 Feb; 147(2):327-31. PMID: 8381630.
      Citations: 5     Fields:    Translation:Animals
    142. Hsiue TR, Garland A, Ray DW, Hershenson MB, Leff AR, Solway J. Endogenous sensory neuropeptide release enhances nonspecific airway responsiveness in guinea pigs. Am Rev Respir Dis. 1992 Jul; 146(1):148-53. PMID: 1320818.
      Citations: 7     Fields:    Translation:AnimalsCells
    143. Strek ME, Garland A, Abrahams C, Leff AR, White SR. Direct effects and augmentation of airway smooth muscle contraction caused by phospholipase A2. Am Rev Respir Dis. 1992 Jun; 145(6):1463-8. PMID: 1596019.
      Citations: 1     Fields:    Translation:Animals
    144. Mitchell RW, Murphy TM, Leff AR. Physiological mechanisms mediating enhanced force generation during development and immune sensitization. Can J Physiol Pharmacol. 1992 Apr; 70(4):615-23. PMID: 1498727.
      Citations: 2     Fields:    Translation:AnimalsPHPublic Health
    145. Ikeda K, Mitchell RW, Guest KA, Seow CY, Kirchhoff CF, Murphy TM, Leff AR. Ontogeny of shortening velocity in porcine trachealis. Am J Physiol. 1992 Mar; 262(3 Pt 1):L280-5. PMID: 1550250.
      Citations: 1     Fields:    Translation:Animals
    146. Covert RF, Schreiber MD, Leff AR, White SR, Munoz NM, Torgerson LJ. Oxygen metabolism and catecholamine secretion during chloralose anesthesia in lambs. J Dev Physiol. 1992 Mar; 17(3):125-32. PMID: 1527368.
      Citations: 2     Fields:    Translation:Animals
    147. White SR, Hathaway DP, Umans JG, Leff AR. Direct effects on airway smooth muscle contractile response caused by endothelin-1 in guinea pig trachealis. Am Rev Respir Dis. 1992 Feb; 145(2 Pt 1):491-3. PMID: 1736763.
      Citations: 3     Fields:    Translation:Animals
    148. Solway J, Leff AR. Sensory neuropeptides and airway function. J Appl Physiol (1985). 1991 Dec; 71(6):2077-87. PMID: 1663932.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    149. White SR, Kulp GV, Spaethe SM, Van Alstyne E, Leff AR. A kinetic assay for eosinophil peroxidase activity in eosinophils and eosinophil conditioned media. J Immunol Methods. 1991 Nov 22; 144(2):257-63. PMID: 1660059.
      Citations: 10     Fields:    Translation:HumansCells
    150. Mitchell RW, Murphy TM, Kelly E, Leff AR. Extracellular Ca2+ mobilization in potential-dependent contraction of trachealis of maturing swine. J Appl Physiol (1985). 1991 Oct; 71(4):1489-95. PMID: 1757374.
      Citations: 1     Fields:    Translation:AnimalsCells
    151. Murphy TM, Mitchell RW, Phillips IJ, Leff AR. Ontogenic expression of acetylcholinesterase activity in trachealis of young swine. Am J Physiol. 1991 Oct; 261(4 Pt 1):L322-6. PMID: 1928367.
      Citations: 2     Fields:    Translation:Animals
    152. White SR, Hathaway DP, Umans JG, Tallet J, Abrahams C, Leff AR. Epithelial modulation of airway smooth muscle response to endothelin-1. Am Rev Respir Dis. 1991 Aug; 144(2):373-8. PMID: 1859062.
      Citations: 6     Fields:    Translation:Animals
    153. Mitchell RW, Kelly E, Leff AR. Reduced activity of acetylcholinesterase in canine tracheal smooth muscle homogenates after active immune-sensitization. Am J Respir Cell Mol Biol. 1991 Jul; 5(1):56-62. PMID: 1908687.
      Citations: 8     Fields:    Translation:AnimalsPHPublic Health
    154. Murphy TM, Mitchell RW, Halayko A, Roach J, Roy L, Kelly EA, Munoz NM, Stephens NL, Leff AR. Effect of maturational changes in myosin content and morphometry on airway smooth muscle contraction. Am J Physiol. 1991 Jun; 260(6 Pt 1):L471-80. PMID: 2058690.
      Citations: 3     Fields:    Translation:Animals
    155. Munoz NM, Kirchhoff CF, Strek ME, Blumenthal RN, Leff AR. Effects of PAF on isolated rat airways perfused with blood-free solution. Am J Physiol. 1991 Apr; 260(4 Pt 1):L260-7. PMID: 2018147.
      Citations: 1     Fields:    Translation:Animals
    156. Leff AR, Hamann KJ, Wegner CD. Inflammation and cell-cell interactions in airway hyperresponsiveness. Am J Physiol. 1991 Apr; 260(4 Pt 1):L189-206. PMID: 2018143.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    157. Mitchell RW, Kelly E, Leff AR. Effect of in vitro preconditioning on tracheal smooth muscle responsiveness. Am J Physiol. 1991 Feb; 260(2 Pt 1):L168-73. PMID: 1996660.
      Citations:    Fields:    Translation:Animals
    158. Murphy TM, Roy L, Phillips IJ, Mitchell RW, Kelly EA, Munoz NM, Leff AR. Effect of maturation on topographic distribution of bronchoconstrictor responses in large diameter airways of young swine. Am Rev Respir Dis. 1991 Jan; 143(1):126-31. PMID: 1670916.
      Citations: 1     Fields:    Translation:Animals
    159. Wylam ME, Samsel RW, Umans JG, Mitchell RW, Leff AR, Schumacker PT. Endotoxin in vivo impairs endothelium-dependent relaxation of canine arteries in vitro. Am Rev Respir Dis. 1990 Dec; 142(6 Pt 1):1263-7. PMID: 2252242.
      Citations: 6     Fields:    Translation:AnimalsCells
    160. Bethel RA, Tanaka DT, Mitchell LS, Curtis SP, Leff AR, Irvin CG. Effect of cooling on the responsiveness of canine tracheal muscle. Am Rev Respir Dis. 1990 Dec; 142(6 Pt 1):1402-6. PMID: 2252259.
      Citations: 2     Fields:    Translation:Animals
    161. Harris IE, Leff AR, Gitelis S, Simon MA. Function after amputation, arthrodesis, or arthroplasty for tumors about the knee. J Bone Joint Surg Am. 1990 Dec; 72(10):1477-85. PMID: 2254355.
      Citations: 41     Fields:    Translation:Humans
    162. Ray DW, Eappen S, Hernandez C, Jackson M, Alger LE, Leff AR, Solway J. Distribution of airway narrowing during hyperpnea-induced bronchoconstriction in guinea pigs. J Appl Physiol (1985). 1990 Oct; 69(4):1323-9. PMID: 2262449.
      Citations: 1     Fields:    Translation:Animals
    163. White SR, Ohno S, Munoz NM, Gleich GJ, Abrahams C, Solway J, Leff AR. Epithelium-dependent contraction of airway smooth muscle caused by eosinophil MBP. Am J Physiol. 1990 Oct; 259(4 Pt 1):L294-303. PMID: 2221089.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    164. Brofman JD, Leff AR, Munoz NM, Kirchhoff C, White SR. Sympathetic secretory response to hypercapnic acidosis in swine. J Appl Physiol (1985). 1990 Aug; 69(2):710-7. PMID: 2121704.
      Citations: 10     Fields:    Translation:Animals
    165. Mitchell RW, Murphy TM, Kelly E, Leff AR. Maturation of acetylcholinesterase expression in tracheal smooth muscle contraction. Am J Physiol. 1990 Aug; 259(2 Pt 1):L130-5. PMID: 2382731.
      Citations:    Fields:    Translation:Animals
    166. Leff AR. Toward the formulation of a theory of asthma. Perspect Biol Med. 1990; 33(2):292-302. PMID: 2406699.
      Citations:    Fields:    Translation:Humans
    167. Shioya T, Munoz NM, Leff AR. Translation of contractile force to constriction in major diameter canine airways in vivo. Am Rev Respir Dis. 1989 Sep; 140(3):687-94. PMID: 2675705.
      Citations:    Fields:    Translation:Animals
    168. Munoz NM, Tutins C, Leff AR. Highly sensitive determination of catecholamine and serotonin concentrations in plasma by liquid chromatography-electrochemistry. J Chromatogr. 1989 Aug 25; 493(1):157-63. PMID: 2778006.
      Citations: 1     Fields:    Translation:HumansAnimals
    169. Koenig SM, Mitchell RW, Kelly E, White SR, Leff AR, Popovich KJ. Beta-adrenergic relaxation of dog trachealis: contractile agonist-specific interaction. J Appl Physiol (1985). 1989 Jul; 67(1):181-5. PMID: 2474528.
      Citations: 1     Fields:    Translation:Animals
    170. Murphy TM, Mitchell RW, Blake JS, Mack MM, Kelly EA, Munoz NM, Leff AR. Expression of airway contractile properties and acetylcholinesterase activity in swine. J Appl Physiol (1985). 1989 Jul; 67(1):174-80. PMID: 2759942.
      Citations: 4     Fields:    Translation:Animals
    171. Leff DR, Leff AR. Tuberculosis control policies in major metropolitan health departments in the United States. IV. Standards in 1988. Am Rev Respir Dis. 1989 Jun; 139(6):1350-5. PMID: 2729748.
      Citations: 2     Fields:    Translation:Humans
    172. Bethel RA, Curtis SP, Lien DC, Irvin CG, Worthen GS, Leff AR, Henson PM. Effect of PAF on parasympathetic contraction of canine airways. J Appl Physiol (1985). 1989 Jun; 66(6):2629-34. PMID: 2745324.
      Citations: 5     Fields:    Translation:Animals
    173. White SR, Blake JS, Murphy TM, Mack MM, Munoz NM, Leff AR. Effects of vasomotor- and mediator-induced hypotension on bronchomotor tone in swine. J Appl Physiol (1985). 1989 Apr; 66(4):1852-9. PMID: 2732177.
      Citations:    Fields:    Translation:Animals
    174. Munoz NM, Stimler-Gerard NP, Mack MM, Tutins C, Blake JS, Kelly E, Murphy TM, Leff AR. Evidence for platelet-activating factor secretion during immune activation in dogs. J Appl Physiol (1985). 1989 Apr; 66(4):1860-6. PMID: 2732178.
      Citations:    Fields:    Translation:Animals
    175. Brofman JD, White SR, Blake JS, Munoz NM, Gleich GJ, Leff AR. Epithelial augmentation of trachealis contraction caused by major basic protein of eosinophils. J Appl Physiol (1985). 1989 Apr; 66(4):1867-73. PMID: 2732179.
      Citations: 10     Fields:    Translation:AnimalsCells
    176. Ray DW, Hernandez C, Leff AR, Drazen JM, Solway J. Tachykinins mediate bronchoconstriction elicited by isocapnic hyperpnea in guinea pigs. J Appl Physiol (1985). 1989 Mar; 66(3):1108-12. PMID: 2496085.
      Citations: 3     Fields:    Translation:Animals
    177. Mitchell RW, Koenig SM, Kelly E, Stephens NL, Leff AR. Ca2+-dependent facilitated shortening in isotonic contraction of trachealis muscle. J Appl Physiol (1985). 1989 Feb; 66(2):632-7. PMID: 2708194.
      Citations:    Fields:    Translation:Animals
    178. Murphy TM, Munoz NM, Moss J, Blake JS, Mack MM, Leff AR. PAF-induced contraction of canine trachea mediated by 5-hydroxytryptamine in vivo. J Appl Physiol (1985). 1989 Feb; 66(2):638-43. PMID: 2708195.
      Citations:    Fields:    Translation:Animals
    179. White SR, Stimler-Gerard NP, Munoz NM, Popovich KJ, Murphy TM, Blake JS, Mack MM, Leff AR. Effect of beta-adrenergic blockade and sympathetic stimulation on canine bronchial mast cell response to immune degranulation in vivo. Am Rev Respir Dis. 1989 Jan; 139(1):73-9. PMID: 2463779.
      Citations:    Fields:    Translation:AnimalsCells
    180. Munoz NM, Chang SW, Murphy TM, Stimler-Gerard NP, Blake J, Mack M, Irvin C, Voelkel NF, Leff AR. Distribution of bronchoconstrictor responses in isolated-perfused rat lung. J Appl Physiol (1985). 1989 Jan; 66(1):202-9. PMID: 2917922.
      Citations: 2     Fields:    Translation:AnimalsCells
    181. Ferguson MK, Little L, Rizzo L, Popovich KJ, Glonek GF, Leff A, Manjoney D, Little AG. Diffusing capacity predicts morbidity and mortality after pulmonary resection. J Thorac Cardiovasc Surg. 1988 Dec; 96(6):894-900. PMID: 3193801.
      Citations: 28     Fields:    Translation:Humans
    182. Kremser CB, Levitt NS, Borow KM, Jaspan JB, Lindbloom C, Polonsky KS, Leff AR. Oxygen uptake kinetics during exercise in diabetic neuropathy. J Appl Physiol (1985). 1988 Dec; 65(6):2665-71. PMID: 3215866.
      Citations: 3     Fields:    Translation:HumansCells
    183. Popovich KJ, Sheldon G, Mack M, Munoz NM, Denberg P, Blake J, White SR, Leff AR. Role of platelets in contraction of canine tracheal muscle elicited by PAF in vitro. J Appl Physiol (1985). 1988 Aug; 65(2):914-20. PMID: 3170437.
      Citations: 4     Fields:    Translation:AnimalsCells
    184. Ray DW, Hernandez C, Munoz N, Leff AR, Solway J. Bronchoconstriction elicited by isocapnic hyperpnea in guinea pigs. J Appl Physiol (1985). 1988 Aug; 65(2):934-9. PMID: 3170439.
      Citations: 4     Fields:    Translation:Animals
    185. White SR, Popovich KJ, Mitchell RW, Koenig SM, Mack MM, Munoz NM, Leff AR. Antagonism of relaxation to isoproterenol caused by agonist interactions. J Appl Physiol (1985). 1988 Jun; 64(6):2501-7. PMID: 3403434.
      Citations:    Fields:    Translation:Animals
    186. Leff AR. Neurohumoral regulation of airway contractile responses. Chest. 1988 Jun; 93(6):1285-7. PMID: 2897271.
      Citations:    Fields:    Translation:HumansAnimals
    187. Leff AR. Endogenous regulation of bronchomotor tone. Am Rev Respir Dis. 1988 May; 137(5):1198-216. PMID: 3057958.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    188. Leff AR, Munoz NM, Shioya T. Comparative distribution of cholinomimetic and parasympathetic contractile responses in the major diameter airways of dogs. Pulm Pharmacol. 1988; 1(3):107-12. PMID: 2980294.
      Citations:    Fields:    Translation:Animals
    189. Murphy TM, Munoz NM, Hirshman CA, Blake JS, Leff AR. Mechanisms of airway hypercontractility in basenji-greyhound dogs. J Appl Physiol (1985). 1987 Nov; 63(5):2008-14. PMID: 3320013.
      Citations:    Fields:    Translation:Animals
    190. Shioya T, Pollack ER, Munoz NM, Leff AR. Distribution of airway contractile responses in major resistance airways of the dog. Am J Pathol. 1987 Oct; 129(1):102-8. PMID: 3310648; PMCID: PMC1899706.
      Citations: 1     Fields:    Translation:Animals
    191. Leff A. Need and responsibility of the NIH to insure that research projects have health-directed applications. Am Rev Respir Dis. 1987 Jul; 136(1):7-8. PMID: 3605846.
      Citations:    Fields:    Translation:HumansAnimals
    192. Breen PH, Becker LJ, Ruygrok P, Mayers I, Long GR, Leff A, Wood LD. Canine bronchoconstriction, gas trapping, and hypoxia with methacholine. J Appl Physiol (1985). 1987 Jul; 63(1):262-9. PMID: 3305467.
      Citations: 3     Fields:    Translation:Animals
    193. Shioya T, Solway J, Munoz NM, Mack M, Leff AR. Distribution of airway contractile responses within the major diameter bronchi during exogenous bronchoconstriction. Am Rev Respir Dis. 1987 May; 135(5):1105-11. PMID: 3555187.
      Citations: 4     Fields:    Translation:Animals
    194. Kremser CB, O'Toole MF, Leff AR. Oscillatory hyperventilation in severe congestive heart failure secondary to idiopathic dilated cardiomyopathy or to ischemic cardiomyopathy. Am J Cardiol. 1987 Apr 01; 59(8):900-5. PMID: 3825954.
      Citations: 26     Fields:    Translation:Humans
    195. Smith HS, Wolman SR, Dairkee SH, Hancock MC, Lippman M, Leff A, Hackett AJ. Immortalization in culture: occurrence at a late stage in the progression of breast cancer. J Natl Cancer Inst. 1987 Apr; 78(4):611-5. PMID: 3470538.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    196. White SR, Sands MF, Popovich KJ, Murphy TM, Munoz NM, Blake J, Mack M, Shioya T, Leff AR. Homeostatic regulation of airway smooth muscle tone by catecholamine secretion in swine. J Appl Physiol (1985). 1987 Mar; 62(3):972-7. PMID: 3471753.
      Citations: 1     Fields:    Translation:Animals
    197. Shioya T, Munoz NM, Leff AR. Effect of resting smooth muscle length on contractile response in resistance airways. J Appl Physiol (1985). 1987 Feb; 62(2):711-7. PMID: 3558230.
      Citations: 3     Fields:    Translation:Humans
    198. Leff AR, White SR, Munoz NM, Popovich KJ, Shioya T, Stimler-Gerard NP. Parasympathetic involvement in PAF-induced contraction in canine trachealis in vivo. J Appl Physiol (1985). 1987 Feb; 62(2):599-605. PMID: 2881917.
      Citations: 5     Fields:    Translation:Animals
    199. Solway J, Leff AR, Dreshaj I, Munoz NM, Ingenito EP, Michaels D, Ingram RH, Drazen JM. Circulatory heat sources for canine respiratory heat exchange. J Clin Invest. 1986 Oct; 78(4):1015-9. PMID: 3760181; PMCID: PMC423747.
      Citations: 4     Fields:    Translation:Animals
    200. Munoz NM, Shioya T, Murphy TM, Primack S, Dame C, Sands MF, Leff AR. Potentiation of vagal contractile response by thromboxane mimetic U-46619. J Appl Physiol (1985). 1986 Sep; 61(3):1173-9. PMID: 3759757.
      Citations: 5     Fields:    Translation:Animals
    201. Tallet J, Munoz NM, Fried R, Leff AR. Endogenous modulation of alpha-adrenergic contraction in canine tracheal muscle. J Appl Physiol (1985). 1986 Aug; 61(2):464-71. PMID: 2875054.
      Citations: 1     Fields:    Translation:Animals
    202. Leff AR, Stimler NP, Munoz NM, Shioya T, Tallet J, Dame C. Augmentation of respiratory mast cell secretion of histamine caused by vagus nerve stimulation during antigen challenge. J Immunol. 1986 Feb 01; 136(3):1066-73. PMID: 2416826.
      Citations: 12     Fields:    Translation:AnimalsCells
    203. Leff AR, Tallet J, Munoz NM, Shoulberg N. Physiological antagonism caused by adrenergic stimulation of canine tracheal muscle. J Appl Physiol (1985). 1986 Jan; 60(1):216-24. PMID: 2867987.
      Citations: 1     Fields:    Translation:Animals
    204. Leff AR, Leff DR. Tuberculosis: a reflection of political institutions and social concerns in the United States. Perspect Biol Med. 1986; 30(1):27-39. PMID: 3797211.
      Citations: 1     Fields:    Translation:Humans
    205. Sands MF, Douglas FL, Green J, Banner AS, Robertson GL, Leff AR. Homeostatic regulation of bronchomotor tone by sympathetic activation during bronchoconstriction in normal and asthmatic humans. Am Rev Respir Dis. 1985 Nov; 132(5):993-8. PMID: 4062054.
      Citations: 1     Fields:    Translation:Humans
    206. Garrity ER, Stimler NP, Munoz NM, Tallet J, David AC, Leff AR. Sympathetic modulation of biochemical and physiological response to immune degranulation in canine bronchial airways in vivo. J Clin Invest. 1985 Jun; 75(6):2038-46. PMID: 2409114; PMCID: PMC425565.
      Citations: 2     Fields:    Translation:AnimalsCells
    207. Leff AR, Munoz NM, Tallet J, Cavigelli M, David AC. Augmentation of parasympathetic contraction in tracheal and bronchial airways by PGF2 alpha in situ. J Appl Physiol (1985). 1985 May; 58(5):1558-64. PMID: 3858274.
      Citations: 1     Fields:    Translation:Animals
    208. Leff AR, Munoz NM, Tallet J, David AC, Cavigelli MA, Garrity ER. Autonomic response characteristics of porcine airway smooth muscle in vivo. J Appl Physiol (1985). 1985 Apr; 58(4):1176-88. PMID: 2859266.
      Citations: 2     Fields:    Translation:Animals
    209. Leff DR, Leff AR. Current treatment modes for tuberculosis. Public policy and implementation. Chest. 1985 Feb; 87(2):139-40. PMID: 3967520.
      Citations: 4     Fields:    Translation:Humans
    210. Leff DR, Leff AR. Tuberculosis control practices in major metropolitan health departments in the United States. 3. Standard of practice in 1984. Chest. 1985 Feb; 87(2):206-11. PMID: 3967528.
      Citations: 1     Fields:    Translation:Humans
    211. Kearns TJ, Cole CH, Farer LS, Leff AR, Reza RJ, Sbarbaro JA, Stead WW. Public health issues in control of tuberculosis. Surveillance techniques and the role of health care providers. Chest. 1985 Feb; 87(2 Suppl):135S-138S. PMID: 3967549.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    212. Munoz NM, Cera LM, Leff AR. Distribution of innervation and circulation in porcine cervical trachea. Am J Vet Res. 1984 Oct; 45(10):1937-40. PMID: 6497090.
      Citations:    Fields:    Translation:Animals
    213. Leff AR, Garrity ER, Munoz NM, Tallet J, Cavigelli M, Deitchman D, Rajfer SI. Selectivity of the intrinsic sympathomimetic activity of the beta-adrenergic blocking drug bucindolol. J Cardiovasc Pharmacol. 1984 Sep-Oct; 6(5):859-66. PMID: 6209492.
      Citations: 1     Fields:    Translation:Animals
    214. Brown JK, Frey MJ, Reed BR, Leff AR, Shields R, Gold WM. Radioenzymatic assay for measurement of tissue concentrations of histamine: adaptation to correct for adherence of histamine to mechanical homogenizers. J Allergy Clin Immunol. 1984 Apr; 73(4):473-8. PMID: 6368647.
      Citations: 1     Fields:    Translation:Animals
    215. Garrity ER, Stimler NP, Munoz NM, Fried R, Leff AR. Response of bronchial smooth muscle to mast cell degranulation in situ. J Appl Physiol Respir Environ Exerc Physiol. 1983 Dec; 55(6):1803-10. PMID: 6662771.
      Citations: 1     Fields:    Translation:AnimalsCells
    216. Leff AR, Munoz NM, Hendrix SG. Parasympathetic and adrenergic contractile responses in canine trachea and bronchus. J Appl Physiol Respir Environ Exerc Physiol. 1983 Jul; 55(1 Pt 1):113-20. PMID: 6885560.
      Citations: 1     Fields:    Translation:AnimalsCells
    217. Leff AR, Brown JK, Frey M, Reed B, Gold WM. Biochemical and physiological effects of compound 48/80 on canine trachea in vivo. J Appl Physiol Respir Environ Exerc Physiol. 1983 Mar; 54(3):720-9. PMID: 6188736.
      Citations: 1     Fields:    Translation:Animals
    218. Leff AR, Munoz NM, Hendrix SG. Comparative distribution of smooth muscle postsynaptic contractile responses in canine trachea and bronchus in vivo. J Pharmacol Exp Ther. 1983 Feb; 224(2):259-64. PMID: 6130142.
      Citations: 1     Fields:    Translation:Animals
    219. Hendrix SG, Munoz NM, Leff AR. Physiological and pharmacological response of canine bronchial smooth muscle in situ. J Appl Physiol Respir Environ Exerc Physiol. 1983 Jan; 54(1):215-24. PMID: 6826407.
      Citations: 3     Fields:    Translation:Animals
    220. Leff A, Rajfer SI, Addington WW. Subtype-specific pharmacology. The magic and the myth. Chest. 1982 Dec; 82(6):661. PMID: 7140389.
      Citations:    Fields:    Translation:Humans
    221. Brown JK, Leff AR, Frey MJ, Reed BR, Lazarus SC, Shields R, Gold WM. Characterization of tracheal mast cell reactions in vivo. Inhibition by a beta-adrenergic agonist. Am Rev Respir Dis. 1982 Nov; 126(5):842-8. PMID: 6183998.
      Citations: 5     Fields:    Translation:AnimalsCells
    222. Leff AR, Munoz NM, Hendrix SG. Sympathetic inhibition of histamine-induced contraction of canine trachealis in vivo. J Appl Physiol Respir Environ Exerc Physiol. 1982 Jul; 53(1):21-9. PMID: 7118633.
      Citations: 1     Fields:    Translation:Animals
    223. Leff A. Patholphysiology of asthmatic bronchoconstriction. Chest. 1982 Jul; 82(1 Suppl):13S-21S. PMID: 6282546.
      Citations: 1     Fields:    Translation:Humans
    224. Leff AR, Munoz NM, Alderman B. Measurement of airway response by isometric and nonisometric techniques in situ. J Appl Physiol Respir Environ Exerc Physiol. 1982 May; 52(5):1363-7. PMID: 7047473.
      Citations: 2     Fields:    Translation:Animals
    225. Leff A. Pathogenesis of asthma. Neurophysiology and pharmacology of bronchospasm. Chest. 1982 Feb; 81(2):224-9. PMID: 6276107.
      Citations: 4     Fields:    Translation:HumansAnimals
    226. Leff AR, Munoz NM. Interrelationship between alpha- and beta-adrenergic agonists and histamine in canine airways. J Allergy Clin Immunol. 1981 Oct; 68(4):300-9. PMID: 6116729.
      Citations:    Fields:    Translation:Animals
    227. Leff AR, Munoz NM. Cholinergic and alpha adrenergic augmentation of histamine-induced contraction of canine airway smooth muscle. J Pharmacol Exp Ther. 1981 Sep; 218(3):582-7. PMID: 6267247.
      Citations: 1     Fields:    Translation:Animals
    228. Leff AR, Munoz NM. Selective autonomic stimulation of canine trachealis with dimethylphenylpiperazinium. J Appl Physiol Respir Environ Exerc Physiol. 1981 Aug; 51(2):428-37. PMID: 6114944.
      Citations: 1     Fields:    Translation:Animals
    229. Leff AR, Munoz NM. Evidence for two subtypes of alpha adrenergic receptors in canine airway smooth muscle. J Pharmacol Exp Ther. 1981 May; 217(2):530-5. PMID: 6262489.
      Citations: 7     Fields:    Translation:Animals
    230. Leff AR, Leff DR, Brewin A. Tuberculosis chemotherapy practices in major metropolitan health departments in the United States. Am Rev Respir Dis. 1981 Feb; 123(2):176-80. PMID: 7235356.
      Citations: 4     Fields:    Translation:Humans
    231. Brown JK, Leff AR, Frey MJ, Reed BR, Gold WM. Physiological and pharmacological properties of canine trachealis muscle in vivo. J Appl Physiol Respir Environ Exerc Physiol. 1980 Jul; 49(1):84-94. PMID: 7399996.
      Citations: 2     Fields:    Translation:Animals
    232. Fein A, Leff A, Hopewell PC. Pathophysiology and management of the complications resulting from fire and the inhaled products of combustion: review of the literature. Crit Care Med. 1980 Feb; 8(2):94-8. PMID: 7353393.
      Citations: 12     Fields:    Translation:Humans
    233. Geppert EF, Leff A. The pathogenesis of pulmonary and miliary tuberculosis. Arch Intern Med. 1979 Dec; 139(12):1381-3. PMID: 518221.
      Citations: 5     Fields:    Translation:HumansCells
    234. Leff A, Herskowitz D, Gibert J, Brewin A. Tuberculosis chemoprophylaxis practices in metropolitan clinics. Am Rev Respir Dis. 1979 Jan; 119(1):161-70. PMID: 420430.
      Citations: 2     Fields:    Translation:Humans
    235. Leff A, Jacobs R, Gooding V, Hauch J, Conte J, Stulbarg M. Bacillus cereus pneumonia. Survival in a patient with cavitary disease treated with gentamicin. Am Rev Respir Dis. 1977 Jan; 115(1):151-4. PMID: 402096.
      Citations: 11     Fields:    Translation:HumansCells
    236. Whitnack E, Leff A, Mohammed S, Gaffney TE. The effect of L-dopa on chronotropic responses to cardioaccelerator nerve stimulation in dogs. J Pharmacol Exp Ther. 1971 May; 177(2):409-14. PMID: 5568797.
      Citations: 3     Fields:    Translation:Animals
    237. Josimovich JB, Wilson EL, Leff A. Vaginal mucification induced by pituitary prolactin and placental lactogen in mice. A luteotrophic test for protein hormone preparations. Gynecol Invest. 1970; 1(4):210-21. PMID: 5522107.
      Citations:    Fields:    Translation:Animals
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