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Stephen Archer to Humans

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This is a "connection" page, showing publications Stephen Archer has written about Humans.
Stephen Archer
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1.775
Humans
  1. Novel Drp1 GTPase Inhibitor, Drpitor1a: Efficacy in Pulmonary Hypertension. Hypertension. 2024 Oct; 81(10):2189-2201.
    View in: PubMed
    Score: 0.031
  2. Complete Revascularization of the Pulmonary Circulation in Chronic Thromboembolic Pulmonary Hypertension: Value of Addressing Chronic Total Occlusions. Can J Cardiol. 2024 Apr; 40(4):634-636.
    View in: PubMed
    Score: 0.030
  3. The Role of Clonal Hematopoiesis of Indeterminant Potential and DNA (Cytosine-5)-Methyltransferase Dysregulation in Pulmonary Arterial Hypertension and Other Cardiovascular Diseases. Cells. 2023 10 26; 12(21).
    View in: PubMed
    Score: 0.029
  4. The Role of Mitochondrial Dynamics and Mitotic Fission in Regulating the Cell Cycle in Cancer and Pulmonary Arterial Hypertension: Implications for Dynamin-Related Protein 1 and Mitofusin2 in Hyperproliferative Diseases. Cells. 2023 07 20; 12(14).
    View in: PubMed
    Score: 0.029
  5. Electron Leak From the Mitochondrial Electron Transport Chain Complex I at Site IQ Is Crucial for Oxygen Sensing in Rabbit and Human Ductus Arteriosus. J Am Heart Assoc. 2023 07 04; 12(13):e029131.
    View in: PubMed
    Score: 0.029
  6. Using omics to breathe new life into our understanding of the ductus arteriosus oxygen response. Semin Perinatol. 2023 03; 47(2):151715.
    View in: PubMed
    Score: 0.028
  7. SARS-CoV-2 mitochondriopathy in COVID-19 pneumonia exacerbates hypoxemia. Redox Biol. 2022 12; 58:102508.
    View in: PubMed
    Score: 0.027
  8. Exertional Dyspnea and Chronotropic Incompetence Caused by Extrinsic Compression of the Right Carotid Body by a Giant Lipoma. Can J Cardiol. 2022 10; 38(10):1588-1590.
    View in: PubMed
    Score: 0.027
  9. Mitochondria in human neutrophils mediate killing of Staphylococcus aureus. Redox Biol. 2022 02; 49:102225.
    View in: PubMed
    Score: 0.026
  10. Carvedilol for Treatment of Right Ventricular Dysfunction in Pulmonary Arterial Hypertension. J Am Heart Assoc. 2021 07 20; 10(14):e021518.
    View in: PubMed
    Score: 0.025
  11. Scientist on the Spot: Exploring the cause and cure for pulmonary arterial hypertension. Cardiovasc Res. 2021 05 25; 117(6):e82-e83.
    View in: PubMed
    Score: 0.025
  12. Oxygen sensing, mitochondrial biology and experimental therapeutics for pulmonary hypertension and cancer. Free Radic Biol Med. 2021 07; 170:150-178.
    View in: PubMed
    Score: 0.024
  13. Providing care for the 99.9% during the COVID-19 pandemic: How ethics, equity, epidemiology, and cost per QALY inform healthcare policy. Healthc Manage Forum. 2020 Sep; 33(5):239-242.
    View in: PubMed
    Score: 0.023
  14. Differentiating COVID-19 Pneumonia From Acute Respiratory Distress Syndrome and High Altitude Pulmonary Edema: Therapeutic Implications. Circulation. 2020 07 14; 142(2):101-104.
    View in: PubMed
    Score: 0.023
  15. An epigenetic increase in mitochondrial fission by MiD49 and MiD51 regulates the cell cycle in cancer: Diagnostic and therapeutic implications. FASEB J. 2020 04; 34(4):5106-5127.
    View in: PubMed
    Score: 0.023
  16. Identification of novel dynamin-related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia-reperfusion injury. FASEB J. 2020 01; 34(1):1447-1464.
    View in: PubMed
    Score: 0.022
  17. Home Virtual Visits for Outpatient Follow-Up Stroke Care: Cross-Sectional Study. J Med Internet Res. 2019 10 07; 21(10):e13734.
    View in: PubMed
    Score: 0.022
  18. Response by Dunham-Snary and Archer to Letter Regarding Article, "Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction". Circ Res. 2019 09 27; 125(8):e35-e36.
    View in: PubMed
    Score: 0.022
  19. Metabolic Syndrome Exacerbates Pulmonary Hypertension due to Left Heart Disease. Circ Res. 2019 08 02; 125(4):449-466.
    View in: PubMed
    Score: 0.022
  20. Repurposing Medications for Treatment of Pulmonary Arterial Hypertension: What's Old Is New Again. J Am Heart Assoc. 2019 01 08; 8(1):e011343.
    View in: PubMed
    Score: 0.021
  21. Transcriptomic Signature of Right Ventricular Failure in Experimental Pulmonary Arterial Hypertension: Deep Sequencing Demonstrates Mitochondrial, Fibrotic, Inflammatory and Angiogenic Abnormalities. Int J Mol Sci. 2018 Sep 12; 19(9).
    View in: PubMed
    Score: 0.021
  22. A Step Closer to Understanding How Riociguat Results in Remodelling of the Right Ventricle in Chronic Thromboembolic Pulmonary Hypertension. Can J Cardiol. 2018 09; 34(9):1098-1101.
    View in: PubMed
    Score: 0.020
  23. Pulmonary arterial hypertension: pathogenesis and clinical management. BMJ. 2018 03 14; 360:j5492.
    View in: PubMed
    Score: 0.020
  24. Increasing Incidence and Prevalence of World Health Organization Groups 1 to 4 Pulmonary Hypertension: A Population-Based Cohort Study in Ontario, Canada. Circ Cardiovasc Qual Outcomes. 2018 02; 11(2):e003973.
    View in: PubMed
    Score: 0.020
  25. Pyruvate Kinase and Warburg Metabolism in Pulmonary Arterial Hypertension: Uncoupled Glycolysis and the Cancer-Like Phenotype of Pulmonary Arterial Hypertension. Circulation. 2017 12 19; 136(25):2486-2490.
    View in: PubMed
    Score: 0.020
  26. Models and Molecular Mechanisms of World Health Organization Group 2 to 4 Pulmonary Hypertension. Hypertension. 2018 01; 71(1):34-55.
    View in: PubMed
    Score: 0.020
  27. MicroRNA-138 and MicroRNA-25 Down-regulate Mitochondrial Calcium Uniporter, Causing the Pulmonary Arterial Hypertension Cancer Phenotype. Am J Respir Crit Care Med. 2017 Feb 15; 195(4):515-529.
    View in: PubMed
    Score: 0.019
  28. The role of Drp1 adaptor proteins MiD49 and MiD51 in mitochondrial fission: implications for human disease. Clin Sci (Lond). 2016 11 01; 130(21):1861-74.
    View in: PubMed
    Score: 0.018
  29. Hypoxic Pulmonary Vasoconstriction: From Molecular Mechanisms to Medicine. Chest. 2017 Jan; 151(1):181-192.
    View in: PubMed
    Score: 0.018
  30. Pulmonary hypertension begets pulmonary hypertension: mutually reinforcing roles for haemodynamics, inflammation, and cancer-like phenotypes. Cardiovasc Res. 2016 07 01; 111(1):1-4.
    View in: PubMed
    Score: 0.018
  31. Acquired Mitochondrial Abnormalities, Including Epigenetic Inhibition of Superoxide Dismutase 2, in Pulmonary Hypertension and Cancer: Therapeutic Implications. Adv Exp Med Biol. 2016; 903:29-53.
    View in: PubMed
    Score: 0.017
  32. Gone fission: an asymptomatic STAT2 mutation elongates mitochondria and causes human disease following viral infection. Brain. 2015 Oct; 138(Pt 10):2802-6.
    View in: PubMed
    Score: 0.017
  33. A mitochondrial redox oxygen sensor in the pulmonary vasculature and ductus arteriosus. Pflugers Arch. 2016 Jan; 468(1):43-58.
    View in: PubMed
    Score: 0.017
  34. Emerging concepts in the molecular basis of pulmonary arterial hypertension: part I: metabolic plasticity and mitochondrial dynamics in the pulmonary circulation and right ventricle in pulmonary arterial hypertension. Circulation. 2015 May 12; 131(19):1691-702.
    View in: PubMed
    Score: 0.016
  35. Mitochondrial dynamics in pulmonary arterial hypertension. J Mol Med (Berl). 2015 Mar; 93(3):229-42.
    View in: PubMed
    Score: 0.016
  36. Mitochondrial dynamics in cardiovascular disease: fission and fusion foretell form and function. J Mol Med (Berl). 2015 Mar; 93(3):225-8.
    View in: PubMed
    Score: 0.016
  37. Right ventricular adaptation and failure in pulmonary arterial hypertension. Can J Cardiol. 2015 Apr; 31(4):391-406.
    View in: PubMed
    Score: 0.016
  38. Soluble guanylate cyclase: a new therapeutic target for pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension. Clin Pharmacol Ther. 2015 Jan; 97(1):88-102.
    View in: PubMed
    Score: 0.016
  39. The right ventricle in pulmonary arterial hypertension: disorders of metabolism, angiogenesis and adrenergic signaling in right ventricular failure. Circ Res. 2014 Jun 20; 115(1):176-88.
    View in: PubMed
    Score: 0.015
  40. Mitochondrial fission and fusion in human diseases. N Engl J Med. 2014 03 13; 370(11):1074.
    View in: PubMed
    Score: 0.015
  41. Mitochondrial dynamics--mitochondrial fission and fusion in human diseases. N Engl J Med. 2013 Dec 05; 369(23):2236-51.
    View in: PubMed
    Score: 0.015
  42. Atrioventricular heart block and syncope coincident with diagnosis of systemic lupus erythematosus. Can J Cardiol. 2013 Oct; 29(10):1330.e5-1330.e7.
    View in: PubMed
    Score: 0.014
  43. Riociguat for pulmonary hypertension--a glass half full. N Engl J Med. 2013 Jul 25; 369(4):386-8.
    View in: PubMed
    Score: 0.014
  44. PGC1a-mediated mitofusin-2 deficiency in female rats and humans with pulmonary arterial hypertension. Am J Respir Crit Care Med. 2013 Apr 15; 187(8):865-78.
    View in: PubMed
    Score: 0.014
  45. The role of redox signaling in epigenetics and cardiovascular disease. Antioxid Redox Signal. 2013 May 20; 18(15):1920-36.
    View in: PubMed
    Score: 0.014
  46. Role of dynamin-related protein 1 (Drp1)-mediated mitochondrial fission in oxygen sensing and constriction of the ductus arteriosus. Circ Res. 2013 Mar 01; 112(5):802-15.
    View in: PubMed
    Score: 0.014
  47. Rodent models of group 1 pulmonary hypertension. Handb Exp Pharmacol. 2013; 218:105-49.
    View in: PubMed
    Score: 0.014
  48. FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate. J Mol Med (Berl). 2013 Mar; 91(3):333-46.
    View in: PubMed
    Score: 0.014
  49. GRK2-mediated inhibition of adrenergic and dopaminergic signaling in right ventricular hypertrophy: therapeutic implications in pulmonary hypertension. Circulation. 2012 Dec 11; 126(24):2859-69.
    View in: PubMed
    Score: 0.014
  50. Evolving epidemiology of pulmonary arterial hypertension. Am J Respir Crit Care Med. 2012 Oct 15; 186(8):707-9.
    View in: PubMed
    Score: 0.014
  51. Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension. Circ Res. 2012 May 25; 110(11):1484-97.
    View in: PubMed
    Score: 0.013
  52. QTc prolongation is associated with impaired right ventricular function and predicts mortality in pulmonary hypertension. Int J Cardiol. 2013 Aug 10; 167(3):669-76.
    View in: PubMed
    Score: 0.013
  53. Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer. FASEB J. 2012 May; 26(5):2175-86.
    View in: PubMed
    Score: 0.013
  54. Pulmonary endarterectomy surgery--a technically demanding cure for WHO Group IV Pulmonary Hypertension: requirements for centres of excellence and availability in Canada. Can J Cardiol. 2011 Nov-Dec; 27(6):671-4.
    View in: PubMed
    Score: 0.013
  55. A KCNE1 missense variant (V47I) causing exercise-induced long QT syndrome (Romano Ward). Int J Cardiol. 2012 Apr 19; 156(2):e33-5.
    View in: PubMed
    Score: 0.013
  56. Paracrine proliferative signaling by senescent cells in world health organization group 3 pulmonary hypertension: age corrupting youth? Circ Res. 2011 Aug 19; 109(5):476-9.
    View in: PubMed
    Score: 0.013
  57. Rodent models of pulmonary hypertension: harmonisation with the world health organisation's categorisation of human PH. Int J Clin Pract Suppl. 2011 Aug; (172):15-34.
    View in: PubMed
    Score: 0.013
  58. A central role for CD68(+) macrophages in hepatopulmonary syndrome. Reversal by macrophage depletion. Am J Respir Crit Care Med. 2011 Apr 15; 183(8):1080-91.
    View in: PubMed
    Score: 0.012
  59. Long-term effects of epoprostenol on the pulmonary vasculature in idiopathic pulmonary arterial hypertension. Chest. 2010 Nov; 138(5):1234-9.
    View in: PubMed
    Score: 0.012
  60. Mitochondrial metabolic adaptation in right ventricular hypertrophy and failure. J Mol Med (Berl). 2010 Oct; 88(10):1011-20.
    View in: PubMed
    Score: 0.012
  61. The role of redox changes in oxygen sensing. Respir Physiol Neurobiol. 2010 Dec 31; 174(3):182-91.
    View in: PubMed
    Score: 0.012
  62. Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: a basis for excessive cell proliferation and a new therapeutic target. Circulation. 2010 Jun 22; 121(24):2661-71.
    View in: PubMed
    Score: 0.012
  63. Basic science of pulmonary arterial hypertension for clinicians: new concepts and experimental therapies. Circulation. 2010 May 11; 121(18):2045-66.
    View in: PubMed
    Score: 0.012
  64. Diagnosis and management of pulmonary hypertension in systemic sclerosis. Curr Rheumatol Rep. 2010 Feb; 12(1):8-18.
    View in: PubMed
    Score: 0.011
  65. A proposed mitochondrial-metabolic mechanism for initiation and maintenance of pulmonary arterial hypertension in fawn-hooded rats: the Warburg model of pulmonary arterial hypertension. Adv Exp Med Biol. 2010; 661:171-85.
    View in: PubMed
    Score: 0.011
  66. The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle. J Mol Med (Berl). 2010 Jan; 88(1):47-60.
    View in: PubMed
    Score: 0.011
  67. Cardiac EASE (Ensuring Access and Speedy Evaluation) - the impact of a single-point-of-entry multidisciplinary outpatient cardiology consultation program on wait times in Canada. Can J Cardiol. 2009 Dec; 25(12):697-702.
    View in: PubMed
    Score: 0.011
  68. Phosphodiesterase type 5 inhibitors for pulmonary arterial hypertension. N Engl J Med. 2009 Nov 05; 361(19):1864-71.
    View in: PubMed
    Score: 0.011
  69. Dilated cardiomyopathy and left bundle branch block associated with ingestion of colloidal gold and silver is reversed by British antiLewisite and vitamin E: the potential toxicity of metals used as health supplements. Can J Cardiol. 2008 May; 24(5):397-9.
    View in: PubMed
    Score: 0.010
  70. Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1alpha-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer. Am J Physiol Heart Circ Physiol. 2008 Feb; 294(2):H570-8.
    View in: PubMed
    Score: 0.010
  71. Potassium channel diversity in the pulmonary arteries and pulmonary veins: implications for regulation of the pulmonary vasculature in health and during pulmonary hypertension. Pharmacol Ther. 2007 Jul; 115(1):56-69.
    View in: PubMed
    Score: 0.009
  72. A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth. Cancer Cell. 2007 Jan; 11(1):37-51.
    View in: PubMed
    Score: 0.009
  73. The role of k+ channels in determining pulmonary vascular tone, oxygen sensing, cell proliferation, and apoptosis: implications in hypoxic pulmonary vasoconstriction and pulmonary arterial hypertension. Microcirculation. 2006 Dec; 13(8):615-32.
    View in: PubMed
    Score: 0.009
  74. Counterpoint: Hypoxic pulmonary vasoconstriction is not mediated by increased production of reactive oxygen species. J Appl Physiol (1985). 2006 Sep; 101(3):995-8; discussion 998.
    View in: PubMed
    Score: 0.009
  75. An evidence-based approach to the management of pulmonary arterial hypertension. Curr Opin Cardiol. 2006 Jul; 21(4):385-92.
    View in: PubMed
    Score: 0.009
  76. Images in cardiovascular medicine. Untreated 37-year-old homozygous familial hypercholesterolemic smoker. Circulation. 2006 May 30; 113(21):e777.
    View in: PubMed
    Score: 0.009
  77. A central role for oxygen-sensitive K+ channels and mitochondria in the specialized oxygen-sensing system. Novartis Found Symp. 2006; 272:157-71; discussion 171-5, 214-7.
    View in: PubMed
    Score: 0.009
  78. Pre-B-cell colony-enhancing factor regulates vascular smooth muscle maturation through a NAD+-dependent mechanism: recognition of a new mechanism for cell diversity and redox regulation of vascular tone and remodeling. Circ Res. 2005 Jul 08; 97(1):4-7.
    View in: PubMed
    Score: 0.008
  79. Hypoxic pulmonary vasoconstriction. J Appl Physiol (1985). 2005 Jan; 98(1):390-403.
    View in: PubMed
    Score: 0.008
  80. Aetiology and management of male erectile dysfunction and female sexual dysfunction in patients with cardiovascular disease. Drugs Aging. 2005; 22(10):823-44.
    View in: PubMed
    Score: 0.008
  81. Differences in food habits and cardiovascular disease risk factors among Native Americans with and without diabetes: the Inter-Tribal Heart Project. Public Health Nutr. 2004 Dec; 7(8):1025-32.
    View in: PubMed
    Score: 0.008
  82. The neurovascular mechanism of clitoral erection: nitric oxide and cGMP-stimulated activation of BKCa channels. FASEB J. 2004 Sep; 18(12):1382-91.
    View in: PubMed
    Score: 0.008
  83. Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells. Circ Res. 2004 Aug 06; 95(3):308-18.
    View in: PubMed
    Score: 0.008
  84. Use of sildenafil for safe improvement of erectile function and quality of life in men with New York Heart Association classes II and III congestive heart failure: a prospective, placebo-controlled, double-blind crossover trial. Arch Intern Med. 2004 Mar 08; 164(5):514-20.
    View in: PubMed
    Score: 0.008
  85. O2 sensing in the human ductus arteriosus: redox-sensitive K+ channels are regulated by mitochondria-derived hydrogen peroxide. Biol Chem. 2004 Mar-Apr; 385(3-4):205-16.
    View in: PubMed
    Score: 0.008
  86. Pulmonary hypertension. Nat Rev Dis Primers. 2024 Jan 04; 10(1):1.
    View in: PubMed
    Score: 0.007
  87. The Herpes Simplex Virus pUL16 and pUL21 Proteins Prevent Capsids from Docking at Nuclear Pore Complexes. PLoS Pathog. 2023 Dec; 19(12):e1011832.
    View in: PubMed
    Score: 0.007
  88. Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension. Circulation. 2003 Oct 28; 108(17):2066-9.
    View in: PubMed
    Score: 0.007
  89. Association of education with dietary intake among young adults in the bi-ethnic Coronary Artery Risk Development in Young Adults (CARDIA) cohort. Public Health Nutr. 2003 Oct; 6(7):689-95.
    View in: PubMed
    Score: 0.007
  90. Multi-omic and multispecies analysis of right ventricular dysfunction. J Heart Lung Transplant. 2024 02; 43(2):303-313.
    View in: PubMed
    Score: 0.007
  91. Effect of Chronic Digoxin Use on Mortality and Heart Failure Hospitalization in Pulmonary Arterial Hypertension. J Am Heart Assoc. 2023 03 21; 12(6):e027559.
    View in: PubMed
    Score: 0.007
  92. Endothelium-derived hyperpolarizing factor in human internal mammary artery is 11,12-epoxyeicosatrienoic acid and causes relaxation by activating smooth muscle BK(Ca) channels. Circulation. 2003 Feb 11; 107(5):769-76.
    View in: PubMed
    Score: 0.007
  93. The NO - K+ channel axis in pulmonary arterial hypertension. Activation by experimental oral therapies. Adv Exp Med Biol. 2003; 543:293-322.
    View in: PubMed
    Score: 0.007
  94. The mechanism(s) of hypoxic pulmonary vasoconstriction: potassium channels, redox O(2) sensors, and controversies. News Physiol Sci. 2002 Aug; 17:131-7.
    View in: PubMed
    Score: 0.007
  95. Diversity in mitochondrial function explains differences in vascular oxygen sensing. Circ Res. 2002 Jun 28; 90(12):1307-15.
    View in: PubMed
    Score: 0.007
  96. Oral sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary arterial hypertension: comparison with inhaled nitric oxide. Circulation. 2002 May 21; 105(20):2398-403.
    View in: PubMed
    Score: 0.007
  97. Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance. Nat Cell Biol. 2022 02; 24(2):168-180.
    View in: PubMed
    Score: 0.007
  98. PINK1-induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial hypertension. FASEB J. 2021 08; 35(8):e21771.
    View in: PubMed
    Score: 0.006
  99. The molecular mechanisms of oxygen-sensing in human ductus arteriosus smooth muscle cells: A comprehensive transcriptome profile reveals a central role for mitochondria. Genomics. 2021 09; 113(5):3128-3140.
    View in: PubMed
    Score: 0.006
  100. Diagnosis and Treatment of Right Heart Failure in Pulmonary Vascular Diseases: A National Heart, Lung, and Blood Institute Workshop. Circ Heart Fail. 2021 06; 14(6).
    View in: PubMed
    Score: 0.006
  101. Gene transfer and metabolic modulators as new therapies for pulmonary hypertension. Increasing expression and activity of potassium channels in rat and human models. Adv Exp Med Biol. 2001; 502:401-18.
    View in: PubMed
    Score: 0.006
  102. Primary pulmonary hypertension: a vascular biology and translational research "Work in progress". Circulation. 2000 Nov 28; 102(22):2781-91.
    View in: PubMed
    Score: 0.006
  103. Sildenafil: from the bench to the bedside. CMAJ. 2000 Oct 31; 163(9):1171-5.
    View in: PubMed
    Score: 0.006
  104. Endothelial BMPR2 Loss Drives a Proliferative Response to BMP (Bone Morphogenetic Protein) 9 via Prolonged Canonical Signaling. Arterioscler Thromb Vasc Biol. 2020 11; 40(11):2605-2618.
    View in: PubMed
    Score: 0.006
  105. Excess Protein O-GlcNAcylation Links Metabolic Derangements to Right Ventricular Dysfunction in Pulmonary Arterial Hypertension. Int J Mol Sci. 2020 Oct 01; 21(19).
    View in: PubMed
    Score: 0.006
  106. Identification of Long Noncoding RNA H19 as a New Biomarker and Therapeutic Target in Right Ventricular Failure in Pulmonary Arterial Hypertension. Circulation. 2020 10 13; 142(15):1464-1484.
    View in: PubMed
    Score: 0.006
  107. Voltage-gated potassium channels in human ductus arteriosus. Lancet. 2000 Jul 08; 356(9224):134-7.
    View in: PubMed
    Score: 0.006
  108. Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension. Circulation. 2020 06 16; 141(24):1986-2000.
    View in: PubMed
    Score: 0.006
  109. Mitochondria in the Pulmonary Vasculature in Health and Disease: Oxygen-Sensing, Metabolism, and Dynamics. Compr Physiol. 2020 03 12; 10(2):713-765.
    View in: PubMed
    Score: 0.006
  110. Hypochloremia Is a Noninvasive Predictor of Mortality in Pulmonary Arterial Hypertension. J Am Heart Assoc. 2020 03 03; 9(5):e015221.
    View in: PubMed
    Score: 0.006
  111. Molecular identification of O2 sensors and O2-sensitive potassium channels in the pulmonary circulation. Adv Exp Med Biol. 2000; 475:219-40.
    View in: PubMed
    Score: 0.006
  112. Clinical Determinants and Prognostic Implications of Right Ventricular Dysfunction in Pulmonary Hypertension Caused by Chronic Lung Disease. J Am Heart Assoc. 2019 01 22; 8(2):e011464.
    View in: PubMed
    Score: 0.005
  113. Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis. Lancet Respir Med. 2019 03; 7(3):227-238.
    View in: PubMed
    Score: 0.005
  114. Relationship between changes in dietary sucrose and high density lipoprotein cholesterol: the CARDIA study. Coronary Artery Risk Development in Young Adults. Ann Epidemiol. 1998 Oct; 8(7):433-8.
    View in: PubMed
    Score: 0.005
  115. Nitric oxide deficiency in fenfluramine- and dexfenfluramine-induced pulmonary hypertension. Am J Respir Crit Care Med. 1998 Oct; 158(4):1061-7.
    View in: PubMed
    Score: 0.005
  116. Survival in pulmonary hypertension due to chronic lung disease: Influence of low diffusion capacity of the lungs for carbon monoxide. J Heart Lung Transplant. 2019 02; 38(2):145-155.
    View in: PubMed
    Score: 0.005
  117. A role for potassium channels in smooth muscle cells and platelets in the etiology of primary pulmonary hypertension. Chest. 1998 Sep; 114(3 Suppl):200S-204S.
    View in: PubMed
    Score: 0.005
  118. Assessment of Right Ventricular Function in the Research Setting: Knowledge Gaps and Pathways Forward. An Official American Thoracic Society Research Statement. Am J Respir Crit Care Med. 2018 08 15; 198(4):e15-e43.
    View in: PubMed
    Score: 0.005
  119. Association of dietary fish and n-3 fatty acid intake with hemostatic factors in the coronary artery risk development in young adults (CARDIA) study. Arterioscler Thromb Vasc Biol. 1998 Jul; 18(7):1119-23.
    View in: PubMed
    Score: 0.005
  120. Pulmonary vasoconstriction, oxygen sensing, and the role of ion channels: Thomas A. Neff lecture. Chest. 1998 Jul; 114(1 Suppl):17S-22S.
    View in: PubMed
    Score: 0.005
  121. A pro-con debate: current controversies in PAH pathogenesis at the American Thoracic Society International Conference in 2017. Am J Physiol Lung Cell Mol Physiol. 2018 10 01; 315(4):L502-L516.
    View in: PubMed
    Score: 0.005
  122. Disproportionate Right Ventricular Dysfunction and Poor Survival in Group 3 Pulmonary Hypertension. Am J Respir Crit Care Med. 2018 06 01; 197(11):1496-1499.
    View in: PubMed
    Score: 0.005
  123. Standards and Methodological Rigor in Pulmonary Arterial Hypertension Preclinical and Translational Research. Circ Res. 2018 03 30; 122(7):1021-1032.
    View in: PubMed
    Score: 0.005
  124. Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension: Mechanistic and Therapeutic Implications. Circulation. 2018 07 17; 138(3):287-304.
    View in: PubMed
    Score: 0.005
  125. The measurement of NO in biological systems using chemiluminescence. Methods Mol Biol. 1998; 100:111-27.
    View in: PubMed
    Score: 0.005
  126. Abnormal angiogenesis in blood outgrowth endothelial cells derived from von Willebrand disease patients. Blood Coagul Fibrinolysis. 2017 Oct; 28(7):521-533.
    View in: PubMed
    Score: 0.005
  127. Interleukin-6 is independently associated with right ventricular function in pulmonary arterial hypertension. J Heart Lung Transplant. 2018 03; 37(3):376-384.
    View in: PubMed
    Score: 0.005
  128. Potassium channel diversity in vascular smooth muscle cells. Can J Physiol Pharmacol. 1997 Jul; 75(7):889-97.
    View in: PubMed
    Score: 0.005
  129. Origins of breath nitric oxide in humans. Chest. 1996 Oct; 110(4):930-8.
    View in: PubMed
    Score: 0.005
  130. Critical Genomic Networks and Vasoreactive Variants in Idiopathic Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2016 08 15; 194(4):464-75.
    View in: PubMed
    Score: 0.004
  131. A placebo-controlled trial of prostacyclin in acute respiratory failure in COPD. Chest. 1996 Mar; 109(3):750-5.
    View in: PubMed
    Score: 0.004
  132. Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society. Circulation. 2015 Nov 24; 132(21):2037-99.
    View in: PubMed
    Score: 0.004
  133. The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels. FASEB J. 1995 Feb; 9(2):183-9.
    View in: PubMed
    Score: 0.004
  134. Peripheral blood signature of vasodilator-responsive pulmonary arterial hypertension. Circulation. 2015 Jan 27; 131(4):401-9; discussion 409.
    View in: PubMed
    Score: 0.004
  135. Activation of the EGFR/p38/JNK pathway by mitochondrial-derived hydrogen peroxide contributes to oxygen-induced contraction of ductus arteriosus. J Mol Med (Berl). 2014 Sep; 92(9):995-1007.
    View in: PubMed
    Score: 0.004
  136. An official American Thoracic Society Statement: pulmonary hypertension phenotypes. Am J Respir Crit Care Med. 2014 Feb 01; 189(3):345-55.
    View in: PubMed
    Score: 0.004
  137. Usefulness of mean aortic valve gradient and left ventricular diastolic filling pattern for distinguishing symptomatic from asymptomatic patients. Am J Cardiol. 1994 Feb 01; 73(4):275-81.
    View in: PubMed
    Score: 0.004
  138. Relevant issues in the pathology and pathobiology of pulmonary hypertension. J Am Coll Cardiol. 2013 Dec 24; 62(25 Suppl):D4-12.
    View in: PubMed
    Score: 0.004
  139. SIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stress. Mol Cell Biol. 2014 Mar; 34(5):807-19.
    View in: PubMed
    Score: 0.004
  140. Diagnosis of pulmonary vein varix by transesophageal echocardiography. Chest. 1993 Jun; 103(6):1901-3.
    View in: PubMed
    Score: 0.004
  141. Measurement of nitric oxide in biological models. FASEB J. 1993 Feb 01; 7(2):349-60.
    View in: PubMed
    Score: 0.003
  142. Noninvasive cardiac output measurements in patients with pulmonary hypertension. Eur Respir J. 2013 Jul; 42(1):125-33.
    View in: PubMed
    Score: 0.003
  143. Persistence of complex vascular lesions despite prolonged prostacyclin therapy of pulmonary arterial hypertension. Histopathology. 2012 Oct; 61(4):597-609.
    View in: PubMed
    Score: 0.003
  144. Late gadolinium enhancement cardiovascular magnetic resonance predicts clinical worsening in patients with pulmonary hypertension. J Cardiovasc Magn Reson. 2012 Feb 01; 14:11.
    View in: PubMed
    Score: 0.003
  145. Myocardial damage in patients with sarcoidosis and preserved left ventricular systolic function: an observational study. Eur J Heart Fail. 2011 Nov; 13(11):1231-7.
    View in: PubMed
    Score: 0.003
  146. Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, and chronic thromboembolic pulmonary hypertension: a scientific statement from the American Heart Association. Circulation. 2011 Apr 26; 123(16):1788-830.
    View in: PubMed
    Score: 0.003
  147. Strategic plan for lung vascular research: An NHLBI-ORDR Workshop Report. Am J Respir Crit Care Med. 2010 Dec 15; 182(12):1554-62.
    View in: PubMed
    Score: 0.003
  148. Five-year follow-up of a multicenter, double-blind randomized clinical trial of laparoscopic Nissen vs anterior 90 degrees partial fundoplication. Arch Surg. 2010 Jun; 145(6):552-7.
    View in: PubMed
    Score: 0.003
  149. The membrane protein MiRP3 regulates Kv4.2 channels in a KChIP-dependent manner. J Physiol. 2010 Jul 15; 588(Pt 14):2657-68.
    View in: PubMed
    Score: 0.003
  150. Survival in pulmonary arterial hypertension: a reappraisal of the NIH risk stratification equation. Eur Respir J. 2010 May; 35(5):1079-87.
    View in: PubMed
    Score: 0.003
  151. A dosing/cross-development study of the multikinase inhibitor sorafenib in patients with pulmonary arterial hypertension. Clin Pharmacol Ther. 2010 Mar; 87(3):303-10.
    View in: PubMed
    Score: 0.003
  152. Carbon monoxide diffusing capacity and mortality in pulmonary arterial hypertension. J Heart Lung Transplant. 2010 Feb; 29(2):181-7.
    View in: PubMed
    Score: 0.003
  153. Cellular and molecular basis of pulmonary arterial hypertension. J Am Coll Cardiol. 2009 Jun 30; 54(1 Suppl):S20-S31.
    View in: PubMed
    Score: 0.003
  154. The association between erectile dysfunction and peripheral arterial disease as determined by screening ankle-brachial index testing. Atherosclerosis. 2009 Dec; 207(2):440-4.
    View in: PubMed
    Score: 0.003
  155. Value of exercise treadmill testing in the risk stratification of patients with pulmonary hypertension. Circ Heart Fail. 2009 Jul; 2(4):278-86.
    View in: PubMed
    Score: 0.003
  156. ACCF/AHA 2009 expert consensus document on pulmonary hypertension a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association developed in collaboration with the American College of Chest Physicians; American Thoracic Society, Inc.; and the Pulmonary Hypertension Association. J Am Coll Cardiol. 2009 Apr 28; 53(17):1573-619.
    View in: PubMed
    Score: 0.003
  157. ACCF/AHA 2009 expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: developed in collaboration with the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association. Circulation. 2009 Apr 28; 119(16):2250-94.
    View in: PubMed
    Score: 0.003
  158. Blunted hypoxic pulmonary vasoconstriction in experimental neonatal chronic lung disease. Am J Respir Crit Care Med. 2008 Aug 15; 178(4):399-406.
    View in: PubMed
    Score: 0.003
  159. Association of serum creatinine with abnormal hemodynamics and mortality in pulmonary arterial hypertension. Circulation. 2008 May 13; 117(19):2475-83.
    View in: PubMed
    Score: 0.003
  160. Developmental absence of the O2 sensitivity of L-type calcium channels in preterm ductus arteriosus smooth muscle cells impairs O2 constriction contributing to patent ductus arteriosus. Pediatr Res. 2008 Feb; 63(2):176-81.
    View in: PubMed
    Score: 0.002
  161. Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility. Circulation. 2007 Jul 17; 116(3):238-48.
    View in: PubMed
    Score: 0.002
  162. The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted. Proc Natl Acad Sci U S A. 2007 Jul 03; 104(27):11418-23.
    View in: PubMed
    Score: 0.002
  163. Exercise thallium testing in ventricular preexcitation. Am J Cardiol. 1987 May 01; 59(12):1103-6.
    View in: PubMed
    Score: 0.002
  164. Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen species: a newly recognized mechanism for sustaining ductal constriction. Circulation. 2007 Apr 03; 115(13):1777-88.
    View in: PubMed
    Score: 0.002
  165. Angiogenic gene therapy in patients with nonrevascularizable ischemic heart disease: a phase 2 randomized, controlled trial of AdVEGF(121) (AdVEGF121) versus maximum medical treatment. Gene Ther. 2006 Nov; 13(21):1503-11.
    View in: PubMed
    Score: 0.002
  166. Redox status in the control of pulmonary vascular tone. Herz. 1986 Jun; 11(3):127-41.
    View in: PubMed
    Score: 0.002
  167. An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension. Circulation. 2006 Jun 06; 113(22):2630-41.
    View in: PubMed
    Score: 0.002
  168. Acute oxygen-sensing mechanisms. N Engl J Med. 2005 Nov 10; 353(19):2042-55.
    View in: PubMed
    Score: 0.002
  169. Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury: evidence that angiogenesis participates in alveolarization. Circulation. 2005 Oct 18; 112(16):2477-86.
    View in: PubMed
    Score: 0.002
  170. Canadian Cardiovascular Society and Canadian Thoracic Society position statement on pulmonary arterial hypertension. Can J Cardiol. 2005 Sep; 21(11):909-14.
    View in: PubMed
    Score: 0.002
  171. Canadian Cardiovascular Society and Canadian Thoracic Society position statement on pulmonary arterial hypertension. Can Respir J. 2005 Sep; 12(6):303-15.
    View in: PubMed
    Score: 0.002
  172. Pergolide is an inhibitor of voltage-gated potassium channels, including Kv1.5, and causes pulmonary vasoconstriction. Circulation. 2005 Sep 06; 112(10):1494-9.
    View in: PubMed
    Score: 0.002
  173. Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension. J Clin Invest. 2005 Jun; 115(6):1479-91.
    View in: PubMed
    Score: 0.002
  174. Hypoxic pulmonary vasoconstriction: redox regulation of O2-sensitive K+ channels by a mitochondrial O2-sensor in resistance artery smooth muscle cells. J Mol Cell Cardiol. 2004 Dec; 37(6):1119-36.
    View in: PubMed
    Score: 0.002
  175. Oxygen-sensitive Kv channel gene transfer confers oxygen responsiveness to preterm rabbit and remodeled human ductus arteriosus: implications for infants with patent ductus arteriosus. Circulation. 2004 Sep 14; 110(11):1372-9.
    View in: PubMed
    Score: 0.002
  176. Pulmonary arterial hypertension: future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop. Circulation. 2004 Jun 22; 109(24):2947-52.
    View in: PubMed
    Score: 0.002
  177. Cellular and molecular pathobiology of pulmonary arterial hypertension. J Am Coll Cardiol. 2004 Jun 16; 43(12 Suppl S):13S-24S.
    View in: PubMed
    Score: 0.002
  178. Innovative strategic Canadian research training from TomorrOw's Research Cardiovascular Health Care Professionals (TORCH). Clin Invest Med. 2004 Feb; 27(1):33-41.
    View in: PubMed
    Score: 0.002
  179. Pulmonary and systemic nitric oxide measurements during CCK-5-induced panic attacks. Neuropsychopharmacology. 2003 Oct; 28(10):1840-5.
    View in: PubMed
    Score: 0.002
  180. O2 sensing in the human ductus arteriosus: regulation of voltage-gated K+ channels in smooth muscle cells by a mitochondrial redox sensor. Circ Res. 2002 Sep 20; 91(6):478-86.
    View in: PubMed
    Score: 0.002
  181. Hypoxic fetoplacental vasoconstriction in humans is mediated by potassium channel inhibition. Am J Physiol Heart Circ Physiol. 2002 Dec; 283(6):H2440-9.
    View in: PubMed
    Score: 0.002
  182. Case 2. Recurrence of myocardial infarction. Can J Cardiol. 2000 Aug; 16 Suppl E:24E-26E.
    View in: PubMed
    Score: 0.001
  183. Ion channels in the pulmonary vasculature. Pulm Pharmacol Ther. 1997 Oct-Dec; 10(5-6):243-52.
    View in: PubMed
    Score: 0.001
  184. Acute hypoxic pulmonary vasoconstriction: a model of oxygen sensing. Physiol Res. 1995; 44(6):361-7.
    View in: PubMed
    Score: 0.001
  185. Chronic primary and secondary thromboembolic pulmonary hypertension. Chest. 1988 Mar; 93(3 Suppl):149S-154S.
    View in: PubMed
    Score: 0.001
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Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.