Dorothy Hanck to Ion Channel Gating
This is a "connection" page, showing publications Dorothy Hanck has written about Ion Channel Gating.
Connection Strength
4.059
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Lidocaine partially depolarizes the S4 segment in domain IV of the sodium channel. Pflugers Arch. 2011 Jan; 461(1):91-7.
Score: 0.315
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Using lidocaine and benzocaine to link sodium channel molecular conformations to state-dependent antiarrhythmic drug affinity. Circ Res. 2009 Aug 28; 105(5):492-9.
Score: 0.289
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Evidence for multiple effects of ProTxII on activation gating in Na(V)1.5. Toxicon. 2008 Sep 01; 52(3):489-500.
Score: 0.268
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The relationship between single-channel and whole-cell conductance in the T-type Ca2+ channel CaV3.1. Biophys J. 2008 Jul; 95(2):931-41.
Score: 0.263
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Outward stabilization of the S4 segments in domains III and IV enhances lidocaine block of sodium channels. J Physiol. 2007 Jul 01; 582(Pt 1):317-34.
Score: 0.248
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Site-3 toxins and cardiac sodium channels. Toxicon. 2007 Feb; 49(2):181-93.
Score: 0.237
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An inner pore residue (Asn406) in the Nav1.5 channel controls slow inactivation and enhances mibefradil block to T-type Ca2+ channel levels. Mol Pharmacol. 2006 Nov; 70(5):1514-23.
Score: 0.235
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Role of Domain IV/S4 outermost arginines in gating of T-type calcium channels. Pflugers Arch. 2005 Nov; 451(2):349-61.
Score: 0.220
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Charge immobilization of the voltage sensor in domain IV is independent of sodium current inactivation. J Physiol. 2005 Feb 15; 563(Pt 1):83-93.
Score: 0.209
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Polyvalent cations constitute the voltage gating particle in human connexin37 hemichannels. J Gen Physiol. 2004 Nov; 124(5):587-603.
Score: 0.208
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The role of the putative inactivation lid in sodium channel gating current immobilization. J Gen Physiol. 2000 May; 115(5):609-20.
Score: 0.152
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Lidocaine alters activation gating of cardiac Na channels. Pflugers Arch. 2000 Apr; 439(6):814-21.
Score: 0.151
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Gating of skeletal and cardiac muscle sodium channels in mammalian cells. J Physiol. 1999 Jan 15; 514 ( Pt 2):425-36.
Score: 0.139
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Nonequilibrium response spectroscopy of voltage-sensitive ion channel gating. Biophys J. 1998 Jan; 74(1):210-29.
Score: 0.129
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Optimization of a mammalian expression system for the measurement of sodium channel gating currents. Am J Physiol. 1996 Sep; 271(3 Pt 1):C1001-6.
Score: 0.118
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Modification of inactivation in cardiac sodium channels: ionic current studies with Anthopleurin-A toxin. J Gen Physiol. 1995 Oct; 106(4):601-16.
Score: 0.111
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Voltage-dependent open-state inactivation of cardiac sodium channels: gating current studies with Anthopleurin-A toxin. J Gen Physiol. 1995 Oct; 106(4):617-40.
Score: 0.111
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Kinetic effects of quaternary lidocaine block of cardiac sodium channels: a gating current study. J Gen Physiol. 1994 Jan; 103(1):19-43.
Score: 0.098
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Gating currents associated with Na channels in canine cardiac Purkinje cells. J Gen Physiol. 1990 Mar; 95(3):439-57.
Score: 0.075
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Sodium channel molecular conformations and antiarrhythmic drug affinity. Trends Cardiovasc Med. 2010 Jan; 20(1):16-21.
Score: 0.074
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Charge at the lidocaine binding site residue Phe-1759 affects permeation in human cardiac voltage-gated sodium channels. J Physiol. 2007 Jun 01; 581(Pt 2):741-55.
Score: 0.061
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Isoform-dependent interaction of voltage-gated sodium channels with protons. J Physiol. 2006 Oct 15; 576(Pt 2):493-501.
Score: 0.059
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State-dependent verapamil block of the cloned human Ca(v)3.1 T-type Ca(2+) channel. Mol Pharmacol. 2006 Aug; 70(2):718-26.
Score: 0.058
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Molecular action of lidocaine on the voltage sensors of sodium channels. J Gen Physiol. 2003 Feb; 121(2):163-75.
Score: 0.046
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The outermost lysine in the S4 of domain III contributes little to the gating charge in sodium channels. Biophys J. 2002 Jun; 82(6):3048-55.
Score: 0.044
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The Na channel voltage sensor associated with inactivation is localized to the external charged residues of domain IV, S4. Biophys J. 1999 Aug; 77(2):747-57.
Score: 0.036
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Augmentation of recovery from inactivation by site-3 Na channel toxins. A single-channel and whole-cell study of persistent currents. J Gen Physiol. 1999 Feb; 113(2):333-46.
Score: 0.035
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Heartthrobs. Science. 1998 Feb 13; 279(5353):1004.
Score: 0.033
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An intact connexin N-terminus is required for function but not gap junction formation. J Cell Sci. 2008 Aug 15; 121(Pt 16):2744-50.
Score: 0.017
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Role for Pro-13 in directing high-affinity binding of anthopleurin B to the voltage-sensitive sodium channel. Biochemistry. 1996 Nov 12; 35(45):14157-64.
Score: 0.007
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The role of exposed tryptophan residues in the activity of the cardiotonic polypeptide anthopleurin B. J Biol Chem. 1996 Sep 27; 271(39):23828-35.
Score: 0.007
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A structural motif for the voltage-gated potassium channel pore. Proc Natl Acad Sci U S A. 1995 Sep 26; 92(20):9215-9.
Score: 0.007