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Connection

Le Shen to Animals

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This is a "connection" page, showing publications Le Shen has written about Animals.
Le Shen
Connection Strength
0.456
Animals
  1. Tight junctions on the move: molecular mechanisms for epithelial barrier regulation. Ann N Y Acad Sci. 2012 Jul; 1258:9-18.
    View in: PubMed
    Score: 0.028
  2. Tight junction pore and leak pathways: a dynamic duo. Annu Rev Physiol. 2011; 73:283-309.
    View in: PubMed
    Score: 0.025
  3. Regulation of the Paneth cell niche by exogenous L-arginine couples the intestinal stem cell function. FASEB J. 2020 08; 34(8):10299-10315.
    View in: PubMed
    Score: 0.024
  4. Functional morphology of the gastrointestinal tract. Curr Top Microbiol Immunol. 2009; 337:1-35.
    View in: PubMed
    Score: 0.022
  5. Intercellular junctions: actin the PARt. Curr Biol. 2008 Nov 11; 18(21):R1014-7.
    View in: PubMed
    Score: 0.021
  6. The tight junction protein complex undergoes rapid and continuous molecular remodeling at steady state. J Cell Biol. 2008 May 19; 181(4):683-95.
    View in: PubMed
    Score: 0.021
  7. Role of epithelial cells in initiation and propagation of intestinal inflammation. Eliminating the static: tight junction dynamics exposed. Am J Physiol Gastrointest Liver Physiol. 2006 Apr; 290(4):G577-82.
    View in: PubMed
    Score: 0.018
  8. Actin depolymerization disrupts tight junctions via caveolae-mediated endocytosis. Mol Biol Cell. 2005 Sep; 16(9):3919-36.
    View in: PubMed
    Score: 0.017
  9. Circulating Plasma miRNA Homologs in Mice and Humans Reflect Familial Cerebral Cavernous Malformation Disease. Transl Stroke Res. 2023 08; 14(4):513-529.
    View in: PubMed
    Score: 0.014
  10. Antiparasitic mebendazole (MBZ) effectively overcomes cisplatin resistance in human ovarian cancer cells by inhibiting multiple cancer-associated signaling pathways. Aging (Albany NY). 2021 07 07; 13(13):17407-17427.
    View in: PubMed
    Score: 0.013
  11. Novel Murine Models of Cerebral Cavernous Malformations. Angiogenesis. 2020 11; 23(4):651-666.
    View in: PubMed
    Score: 0.012
  12. ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction. Circ Res. 2020 07 03; 127(2):e28-e43.
    View in: PubMed
    Score: 0.012
  13. Computational Modeling of Claudin Structure and Function. Int J Mol Sci. 2020 Jan 23; 21(3).
    View in: PubMed
    Score: 0.012
  14. Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation. Sci Transl Med. 2019 11 27; 11(520).
    View in: PubMed
    Score: 0.011
  15. Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations. Acta Neuropathol Commun. 2019 08 19; 7(1):132.
    View in: PubMed
    Score: 0.011
  16. Inflammation-induced Occludin Downregulation Limits Epithelial Apoptosis by Suppressing Caspase-3 Expression. Gastroenterology. 2019 11; 157(5):1323-1337.
    View in: PubMed
    Score: 0.011
  17. A calcium transport mechanism for atrial fibrillation in Tbx5-mutant mice. Elife. 2019 03 21; 8.
    View in: PubMed
    Score: 0.011
  18. The scaffolding protein ZO-1 coordinates actomyosin and epithelial apical specializations in vitro and in vivo. J Biol Chem. 2018 11 09; 293(45):17317-17335.
    View in: PubMed
    Score: 0.011
  19. Phenotypic characterization of murine models of cerebral cavernous malformations. Lab Invest. 2019 03; 99(3):319-330.
    View in: PubMed
    Score: 0.010
  20. Molecular determination of claudin-15 organization and channel selectivity. J Gen Physiol. 2018 07 02; 150(7):949-968.
    View in: PubMed
    Score: 0.010
  21. IL-22 Upregulates Epithelial Claudin-2 to Drive Diarrhea and Enteric Pathogen Clearance. Cell Host Microbe. 2017 Jun 14; 21(6):671-681.e4.
    View in: PubMed
    Score: 0.010
  22. Micro-computed tomography in murine models of cerebral cavernous malformations as a paradigm for brain disease. J Neurosci Methods. 2016 09 15; 271:14-24.
    View in: PubMed
    Score: 0.009
  23. Occludin deficiency promotes ethanol-induced disruption of colonic epithelial junctions, gut barrier dysfunction and liver damage in mice. Biochim Biophys Acta. 2016 Apr; 1860(4):765-74.
    View in: PubMed
    Score: 0.009
  24. Claudin-2-dependent paracellular channels are dynamically gated. Elife. 2015 Nov 14; 4:e09906.
    View in: PubMed
    Score: 0.009
  25. Expression of human decay-accelerating factor on intestinal epithelium of transgenic mice does not facilitate infection by the enteral route. J Virol. 2015 Apr; 89(8):4311-8.
    View in: PubMed
    Score: 0.008
  26. Microtubules are required for efficient epithelial tight junction homeostasis and restoration. Am J Physiol Cell Physiol. 2014 Aug 01; 307(3):C245-54.
    View in: PubMed
    Score: 0.008
  27. Overactivation of intestinal SREBP2 in mice increases serum cholesterol. PLoS One. 2014; 9(1):e84221.
    View in: PubMed
    Score: 0.008
  28. TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis. Gastroenterology. 2013 Aug; 145(2):407-15.
    View in: PubMed
    Score: 0.007
  29. Capsaicin induces NKCC1 internalization and inhibits chloride secretion in colonic epithelial cells independently of TRPV1. Am J Physiol Gastrointest Liver Physiol. 2013 Jan 15; 304(2):G142-56.
    View in: PubMed
    Score: 0.007
  30. Dynamic migration of ?d intraepithelial lymphocytes requires occludin. Proc Natl Acad Sci U S A. 2012 May 01; 109(18):7097-102.
    View in: PubMed
    Score: 0.007
  31. The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding. Gastroenterology. 2011 Apr; 140(4):1208-1218.e1-2.
    View in: PubMed
    Score: 0.006
  32. MLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier function. Proc Natl Acad Sci U S A. 2010 May 04; 107(18):8237-41.
    View in: PubMed
    Score: 0.006
  33. Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo. J Cell Biol. 2010 Apr 05; 189(1):111-26.
    View in: PubMed
    Score: 0.006
  34. Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity. J Biol Chem. 2010 Apr 16; 285(16):12037-46.
    View in: PubMed
    Score: 0.006
  35. Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions. Mol Biol Cell. 2010 Apr 01; 21(7):1200-13.
    View in: PubMed
    Score: 0.006
  36. Phorbol 12-myristate 13-acetate-induced endocytosis of the Na-K-2Cl cotransporter in MDCK cells is associated with a clathrin-dependent pathway. Am J Physiol Cell Physiol. 2010 Jan; 298(1):C85-97.
    View in: PubMed
    Score: 0.006
  37. No static at all. Ann N Y Acad Sci. 2009 May; 1165:314-22.
    View in: PubMed
    Score: 0.006
  38. Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis. Gastroenterology. 2009 Feb; 136(2):551-63.
    View in: PubMed
    Score: 0.005
  39. LIGHT signals directly to intestinal epithelia to cause barrier dysfunction via cytoskeletal and endocytic mechanisms. Gastroenterology. 2007 Jun; 132(7):2383-94.
    View in: PubMed
    Score: 0.005
  40. Recognition of host immune activation by Pseudomonas aeruginosa. Science. 2005 Jul 29; 309(5735):774-7.
    View in: PubMed
    Score: 0.004
  41. A porous defense: the leaky epithelial barrier in intestinal disease. Lab Invest. 2004 Mar; 84(3):282-91.
    View in: PubMed
    Score: 0.004
  42. Molecular ordering of the initial signaling events of CD95. Mol Cell Biol. 2002 Jan; 22(1):207-20.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.