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Connection

Le Shen to Humans

This is a "connection" page, showing publications Le Shen has written about Humans.
Connection Strength

0.256
  1. Cerebral Cavernous Malformation Proteins in Barrier Maintenance and Regulation. Int J Mol Sci. 2020 Jan 20; 21(2).
    View in: PubMed
    Score: 0.024
  2. The cerebral cavernous malformation disease causing gene KRIT1 participates in intestinal epithelial barrier maintenance and regulation. FASEB J. 2019 02; 33(2):2132-2143.
    View in: PubMed
    Score: 0.022
  3. The role of molecular remodeling in differential regulation of tight junction permeability. Semin Cell Dev Biol. 2014 Dec; 36:204-12.
    View in: PubMed
    Score: 0.017
  4. Tight junctions on the move: molecular mechanisms for epithelial barrier regulation. Ann N Y Acad Sci. 2012 Jul; 1258:9-18.
    View in: PubMed
    Score: 0.014
  5. Tight junction pore and leak pathways: a dynamic duo. Annu Rev Physiol. 2011; 73:283-309.
    View in: PubMed
    Score: 0.013
  6. Mechanisms and functional implications of intestinal barrier defects. Dig Dis. 2009; 27(4):443-9.
    View in: PubMed
    Score: 0.012
  7. Functional morphology of the gastrointestinal tract. Curr Top Microbiol Immunol. 2009; 337:1-35.
    View in: PubMed
    Score: 0.011
  8. The tight junction protein complex undergoes rapid and continuous molecular remodeling at steady state. J Cell Biol. 2008 May 19; 181(4):683-95.
    View in: PubMed
    Score: 0.011
  9. Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure. J Cell Sci. 2006 May 15; 119(Pt 10):2095-106.
    View in: PubMed
    Score: 0.009
  10. Role of epithelial cells in initiation and propagation of intestinal inflammation. Eliminating the static: tight junction dynamics exposed. Am J Physiol Gastrointest Liver Physiol. 2006 Apr; 290(4):G577-82.
    View in: PubMed
    Score: 0.009
  11. Circulating Plasma miRNA Homologs in Mice and Humans Reflect Familial Cerebral Cavernous Malformation Disease. Transl Stroke Res. 2023 08; 14(4):513-529.
    View in: PubMed
    Score: 0.007
  12. Antiparasitic mebendazole (MBZ) effectively overcomes cisplatin resistance in human ovarian cancer cells by inhibiting multiple cancer-associated signaling pathways. Aging (Albany NY). 2021 07 07; 13(13):17407-17427.
    View in: PubMed
    Score: 0.007
  13. Permissive microbiome characterizes human subjects with a neurovascular disease cavernous angioma. Nat Commun. 2020 05 27; 11(1):2659.
    View in: PubMed
    Score: 0.006
  14. Antibodies in cerebral cavernous malformations react with cytoskeleton autoantigens in the lesional milieu. J Autoimmun. 2020 09; 113:102469.
    View in: PubMed
    Score: 0.006
  15. ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction. Circ Res. 2020 07 03; 127(2):e28-e43.
    View in: PubMed
    Score: 0.006
  16. Idiopathic pulmonary fibrosis is associated with tight junction protein alterations. Biochim Biophys Acta Biomembr. 2020 05 01; 1862(5):183205.
    View in: PubMed
    Score: 0.006
  17. Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation. Sci Transl Med. 2019 11 27; 11(520).
    View in: PubMed
    Score: 0.006
  18. Inflammation-induced Occludin Downregulation Limits Epithelial Apoptosis by Suppressing Caspase-3 Expression. Gastroenterology. 2019 11; 157(5):1323-1337.
    View in: PubMed
    Score: 0.006
  19. Phenotypic characterization of murine models of cerebral cavernous malformations. Lab Invest. 2019 03; 99(3):319-330.
    View in: PubMed
    Score: 0.005
  20. Occludin deficiency promotes ethanol-induced disruption of colonic epithelial junctions, gut barrier dysfunction and liver damage in mice. Biochim Biophys Acta. 2016 Apr; 1860(4):765-74.
    View in: PubMed
    Score: 0.005
  21. Claudin-2-dependent paracellular channels are dynamically gated. Elife. 2015 Nov 14; 4:e09906.
    View in: PubMed
    Score: 0.005
  22. Expression of human decay-accelerating factor on intestinal epithelium of transgenic mice does not facilitate infection by the enteral route. J Virol. 2015 Apr; 89(8):4311-8.
    View in: PubMed
    Score: 0.004
  23. Microtubules are required for efficient epithelial tight junction homeostasis and restoration. Am J Physiol Cell Physiol. 2014 Aug 01; 307(3):C245-54.
    View in: PubMed
    Score: 0.004
  24. Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux. Mol Biol Cell. 2013 Oct; 24(19):3056-68.
    View in: PubMed
    Score: 0.004
  25. Lymphatic endothelial differentiation in pulmonary lymphangioleiomyomatosis cells. J Histochem Cytochem. 2013 Aug; 61(8):580-90.
    View in: PubMed
    Score: 0.004
  26. Capsaicin induces NKCC1 internalization and inhibits chloride secretion in colonic epithelial cells independently of TRPV1. Am J Physiol Gastrointest Liver Physiol. 2013 Jan 15; 304(2):G142-56.
    View in: PubMed
    Score: 0.004
  27. Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function. J Cell Biol. 2011 May 02; 193(3):565-82.
    View in: PubMed
    Score: 0.003
  28. MLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier function. Proc Natl Acad Sci U S A. 2010 May 04; 107(18):8237-41.
    View in: PubMed
    Score: 0.003
  29. Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity. J Biol Chem. 2010 Apr 16; 285(16):12037-46.
    View in: PubMed
    Score: 0.003
  30. Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions. Mol Biol Cell. 2010 Apr 01; 21(7):1200-13.
    View in: PubMed
    Score: 0.003
  31. No static at all. Ann N Y Acad Sci. 2009 May; 1165:314-22.
    View in: PubMed
    Score: 0.003
  32. Serotonin modifies cytoskeleton and brush-border membrane architecture in human intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2008 Oct; 295(4):G700-8.
    View in: PubMed
    Score: 0.003
  33. LIGHT signals directly to intestinal epithelia to cause barrier dysfunction via cytoskeletal and endocytic mechanisms. Gastroenterology. 2007 Jun; 132(7):2383-94.
    View in: PubMed
    Score: 0.002
  34. Recognition of host immune activation by Pseudomonas aeruginosa. Science. 2005 Jul 29; 309(5735):774-7.
    View in: PubMed
    Score: 0.002
  35. Distinct temporal-spatial roles for rho kinase and myosin light chain kinase in epithelial purse-string wound closure. Gastroenterology. 2005 Apr; 128(4):987-1001.
    View in: PubMed
    Score: 0.002
  36. A porous defense: the leaky epithelial barrier in intestinal disease. Lab Invest. 2004 Mar; 84(3):282-91.
    View in: PubMed
    Score: 0.002
  37. Molecular ordering of the initial signaling events of CD95. Mol Cell Biol. 2002 Jan; 22(1):207-20.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.