Co-Authors
This is a "connection" page, showing publications co-authored by Tong-Chuan He and Hue H. Luu.
Connection Strength
9.574
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Distinct roles of bone morphogenetic proteins in osteogenic differentiation of mesenchymal stem cells. J Orthop Res. 2007 May; 25(5):665-77.
Score: 0.297
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Increased expression of S100A6 is associated with decreased metastasis and inhibition of cell migration and anchorage independent growth in human osteosarcoma. Cancer Lett. 2005 Nov 08; 229(1):135-48.
Score: 0.268
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An orthotopic model of human osteosarcoma growth and spontaneous pulmonary metastasis. Clin Exp Metastasis. 2005; 22(4):319-29.
Score: 0.253
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Wnt/beta-catenin signaling pathway as a novel cancer drug target. Curr Cancer Drug Targets. 2004 Dec; 4(8):653-71.
Score: 0.251
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The inhibition of BRAF activity sensitizes chemoresistant human ovarian cancer cells to paclitaxel-induced cytotoxicity and tumor growth inhibition. Am J Transl Res. 2020; 12(12):8084-8098.
Score: 0.191
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A reverse transcriptase-mediated ribosomal RNA depletion (RTR2D) strategy for the cost-effective construction of RNA sequencing libraries. J Adv Res. 2020 Jul; 24:239-250.
Score: 0.179
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lncRNA Rmst acts as an important mediator of BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs) by antagonizing Notch-targeting microRNAs. Aging (Albany NY). 2019 12 11; 11(24):12476-12496.
Score: 0.178
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Monensin inhibits cell proliferation and tumor growth of chemo-resistant pancreatic cancer cells by targeting the EGFR signaling pathway. Sci Rep. 2018 12 17; 8(1):17914.
Score: 0.166
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BMP9-induced osteoblastic differentiation requires functional Notch signaling in mesenchymal stem cells. Lab Invest. 2019 01; 99(1):58-71.
Score: 0.165
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A Simplified System to Express Circularized Inhibitors of miRNA for Stable and Potent Suppression of miRNA Functions. Mol Ther Nucleic Acids. 2018 Dec 07; 13:556-567.
Score: 0.164
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CRISPR/Cas9-mediated reversibly immortalized mouse bone marrow stromal stem cells (BMSCs) retain multipotent features of mesenchymal stem cells (MSCs). Oncotarget. 2017 Dec 19; 8(67):111847-111865.
Score: 0.155
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lncRNA H19 mediates BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs) through Notch signaling. Oncotarget. 2017 Jun 27.
Score: 0.150
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lncRNA H19 mediates BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs) through Notch signaling. Oncotarget. 2017 Aug 08; 8(32):53581-53601.
Score: 0.150
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An NgAgo tool for genome editing: did CRISPR/Cas9 just find a competitor? Genes Dis. 2016 Sep; 3(3):169-170.
Score: 0.140
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Transition to resistance: An unexpected role of the EMT in cancer chemoresistance. Genes Dis. 2016 Mar; 3(1):3-6.
Score: 0.136
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The Calcium-Binding Protein S100A6 Accelerates Human Osteosarcoma Growth by Promoting Cell Proliferation and Inhibiting Osteogenic Differentiation. Cell Physiol Biochem. 2015; 37(6):2375-92.
Score: 0.135
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The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies. Lab Invest. 2016 Feb; 96(2):116-36.
Score: 0.135
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Molecular pathogenesis and therapeutic strategies of human osteosarcoma. J Biomed Res. 2015 Aug 30; 30.
Score: 0.132
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Insider information: Testing cancer drug sensitivity for personalized therapy. Genes Dis. 2015 Sep; 2(3):219-221.
Score: 0.130
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Sustained high level transgene expression in mammalian cells mediated by the optimized piggyBac transposon system. Genes Dis. 2015 Mar; 2(1):96-105.
Score: 0.128
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A simplified and versatile system for the simultaneous expression of multiple siRNAs in mammalian cells using Gibson DNA Assembly. PLoS One. 2014; 9(11):e113064.
Score: 0.125
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The piggyBac transposon-mediated expression of SV40 T antigen efficiently immortalizes mouse embryonic fibroblasts (MEFs). PLoS One. 2014; 9(5):e97316.
Score: 0.121
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Overexpression of Ad5 precursor terminal protein accelerates recombinant adenovirus packaging and amplification in HEK-293 packaging cells. Gene Ther. 2014 Jul; 21(7):629-37.
Score: 0.121
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Adenovirus-mediated efficient gene transfer into cultured three-dimensional organoids. PLoS One. 2014; 9(4):e93608.
Score: 0.120
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Adenovirus-mediated gene transfer in mesenchymal stem cells can be significantly enhanced by the cationic polymer polybrene. PLoS One. 2014; 9(3):e92908.
Score: 0.120
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Crosstalk between Wnt/ß-catenin and estrogen receptor signaling synergistically promotes osteogenic differentiation of mesenchymal progenitor cells. PLoS One. 2013; 8(12):e82436.
Score: 0.117
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Modulation of ß-catenin signaling by the inhibitors of MAP kinase, tyrosine kinase, and PI3-kinase pathways. Int J Med Sci. 2013; 10(13):1888-98.
Score: 0.117
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The E-F hand calcium-binding protein S100A4 regulates the proliferation, survival and differentiation potential of human osteosarcoma cells. Cell Physiol Biochem. 2013; 32(4):1083-96.
Score: 0.117
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Characterization of scaffold carriers for BMP9-transduced osteoblastic progenitor cells in bone regeneration. J Biomed Mater Res A. 2014 Oct; 102(10):3429-38.
Score: 0.116
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BMP signaling in mesenchymal stem cell differentiation and bone formation. J Biomed Sci Eng. 2013 Aug; 6(8A):32-52.
Score: 0.115
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Decellularized liver scaffolds effectively support the proliferation and differentiation of mouse fetal hepatic progenitors. J Biomed Mater Res A. 2014 Apr; 102(4):1017-25.
Score: 0.113
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IGFBP5 domains exert distinct inhibitory effects on the tumorigenicity and metastasis of human osteosarcoma. Cancer Lett. 2013 Aug 09; 336(1):222-30.
Score: 0.113
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BMP9 signaling in stem cell differentiation and osteogenesis. Am J Stem Cells. 2013; 2(1):1-21.
Score: 0.111
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Wnt signaling in bone formation and its therapeutic potential for bone diseases. Ther Adv Musculoskelet Dis. 2013 Feb; 5(1):13-31.
Score: 0.111
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The Current and Future Therapies for Human Osteosarcoma. Curr Cancer Ther Rev. 2013 Feb; 9(1):55-77.
Score: 0.111
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Growth hormone synergizes with BMP9 in osteogenic differentiation by activating the JAK/STAT/IGF1 pathway in murine multilineage cells. J Bone Miner Res. 2012 Jul; 27(7):1566-75.
Score: 0.106
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Conditional immortalization establishes a repertoire of mouse melanocyte progenitors with distinct melanogenic differentiation potential. J Invest Dermatol. 2012 Oct; 132(10):2479-2483.
Score: 0.105
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Conditionally immortalized mouse embryonic fibroblasts retain proliferative activity without compromising multipotent differentiation potential. PLoS One. 2012; 7(2):e32428.
Score: 0.104
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Epigenetic regulation of mesenchymal stem cells: a focus on osteogenic and adipogenic differentiation. Stem Cells Int. 2011; 2011:201371.
Score: 0.099
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BMP-9 induced osteogenic differentiation of mesenchymal stem cells: molecular mechanism and therapeutic potential. Curr Gene Ther. 2011 Jun; 11(3):229-40.
Score: 0.099
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Defective osteogenic differentiation in the development of osteosarcoma. Sarcoma. 2011; 2011:325238.
Score: 0.097
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The therapeutic potential of the Wnt signaling pathway in bone disorders. Curr Mol Pharmacol. 2011 Jan; 4(1):14-25.
Score: 0.096
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Mesenchymal Progenitor Cells and Their Orthopedic Applications: Forging a Path towards Clinical Trials. Stem Cells Int. 2010 Dec 16; 2010:519028.
Score: 0.095
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Lysophosphatidic acid acyltransferase ß (LPAATß) promotes the tumor growth of human osteosarcoma. PLoS One. 2010 Dec 01; 5(12):e14182.
Score: 0.095
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Tetrandrine inhibits Wnt/ß-catenin signaling and suppresses tumor growth of human colorectal cancer. Mol Pharmacol. 2011 Feb; 79(2):211-9.
Score: 0.095
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Mesenchymal stem cells: Molecular characteristics and clinical applications. World J Stem Cells. 2010 Aug 26; 2(4):67-80.
Score: 0.093
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TGFbeta/BMP type I receptors ALK1 and ALK2 are essential for BMP9-induced osteogenic signaling in mesenchymal stem cells. J Biol Chem. 2010 Sep 17; 285(38):29588-98.
Score: 0.093
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Molecular basis of differentiation therapy for soft tissue sarcomas. Trends Cancer Res. 2010; 6:69-90.
Score: 0.089
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Activation of RXR and RAR signaling promotes myogenic differentiation of myoblastic C2C12 cells. Differentiation. 2009 Nov; 78(4):195-204.
Score: 0.086
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A comprehensive analysis of the dual roles of BMPs in regulating adipogenic and osteogenic differentiation of mesenchymal progenitor cells. Stem Cells Dev. 2009 May; 18(4):545-59.
Score: 0.085
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Establishment and characterization of a new highly metastatic human osteosarcoma cell line. Clin Exp Metastasis. 2009; 26(7):599-610.
Score: 0.085
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Hey1 basic helix-loop-helix protein plays an important role in mediating BMP9-induced osteogenic differentiation of mesenchymal progenitor cells. J Biol Chem. 2009 Jan 02; 284(1):649-659.
Score: 0.082
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BMP-9-induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/beta-catenin signalling. J Cell Mol Med. 2009 Aug; 13(8B):2448-2464.
Score: 0.082
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Osteogenic BMPs promote tumor growth of human osteosarcomas that harbor differentiation defects. Lab Invest. 2008 Dec; 88(12):1264-77.
Score: 0.082
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S100A6 expression and function in human osteosarcoma. Clin Orthop Relat Res. 2008 Sep; 466(9):2060-70.
Score: 0.081
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Regulation of osteogenic differentiation during skeletal development. Front Biosci. 2008 Jan 01; 13:2001-21.
Score: 0.078
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Selection and validation of optimal siRNA target sites for RNAi-mediated gene silencing. Gene. 2007 Jun 15; 395(1-2):160-9.
Score: 0.074
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Wnt signaling and human diseases: what are the therapeutic implications? Lab Invest. 2007 Feb; 87(2):97-103.
Score: 0.073
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Osteosarcoma and osteoblastic differentiation: a new perspective on oncogenesis. Clin Orthop Relat Res. 2007 Jan; 454:237-46.
Score: 0.073
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A protocol for rapid generation of recombinant adenoviruses using the AdEasy system. Nat Protoc. 2007; 2(5):1236-47.
Score: 0.073
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CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells. Mol Cell Biol. 2006 Apr; 26(8):2955-64.
Score: 0.069
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Gene therapy for bone regeneration. Curr Gene Ther. 2005 Apr; 5(2):167-79.
Score: 0.064
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Connective tissue growth factor (CTGF) is regulated by Wnt and bone morphogenetic proteins signaling in osteoblast differentiation of mesenchymal stem cells. J Biol Chem. 2004 Dec 31; 279(53):55958-68.
Score: 0.062
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Inhibitor of DNA binding/differentiation helix-loop-helix proteins mediate bone morphogenetic protein-induced osteoblast differentiation of mesenchymal stem cells. J Biol Chem. 2004 Jul 30; 279(31):32941-9.
Score: 0.061
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Dual regulation of gene expression mediated by tetracycline and Cre recombinase. Biotechniques. 2004 Mar; 36(3):390-2, 394, 396.
Score: 0.060
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Transcriptional characterization of bone morphogenetic proteins (BMPs)-mediated osteogenic signaling. J Cell Biochem. 2003 Dec 15; 90(6):1149-65.
Score: 0.059
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Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs). J Bone Joint Surg Am. 2003 Aug; 85(8):1544-52.
Score: 0.057
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Tyrosine kinase inhibitor STI-571/Gleevec down-regulates the beta-catenin signaling activity. Cancer Lett. 2003 Apr 25; 193(2):161-70.
Score: 0.056
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Long non-coding RNA (LncRNA) HOTAIR regulates BMP9-induced osteogenic differentiation by targeting the proliferation of mesenchymal stem cells (MSCs). Aging (Albany NY). 2021 01 10; 13(3):4199-4214.
Score: 0.048
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Blockade of IGF/IGF-1R signaling axis with soluble IGF-1R mutants suppresses the cell proliferation and tumor growth of human osteosarcoma. Am J Cancer Res. 2020; 10(10):3248-3266.
Score: 0.047
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Highly expressed BMP9/GDF2 in postnatal mouse liver and lungs may account for its pleiotropic effects on stem cell differentiation, angiogenesis, tumor growth and metabolism. Genes Dis. 2020 Jun; 7(2):235-244.
Score: 0.044
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Developing a Versatile Shotgun Cloning Strategy for Single-Vector-Based Multiplex Expression of Short Interfering RNAs (siRNAs) in Mammalian Cells. ACS Synth Biol. 2019 09 20; 8(9):2092-2105.
Score: 0.044
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The wonders of BMP9: From mesenchymal stem cell differentiation, angiogenesis, neurogenesis, tumorigenesis, and metabolism to regenerative medicine. Genes Dis. 2019 Sep; 6(3):201-223.
Score: 0.043
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A simplified system for the effective expression and delivery of functional mature microRNAs in mammalian cells. Cancer Gene Ther. 2020 06; 27(6):424-437.
Score: 0.043
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Transcriptomic landscape regulated by the 14 types of bone morphogenetic proteins (BMPs) in lineage commitment and differentiation of mesenchymal stem cells (MSCs). Genes Dis. 2019 Sep; 6(3):258-275.
Score: 0.043
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Reversibly immortalized human umbilical cord-derived mesenchymal stem cells (UC-MSCs) are responsive to BMP9-induced osteogenic and adipogenic differentiation. J Cell Biochem. 2018 11; 119(11):8872-8886.
Score: 0.041
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A blockade of PI3K? signaling effectively mitigates angiotensin II-induced renal injury and fibrosis in a mouse model. Sci Rep. 2018 Jul 20; 8(1):10988.
Score: 0.040
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Niclosamide Exhibits Potent Anticancer Activity and Synergizes with Sorafenib in Human Renal Cell Cancer Cells. Cell Physiol Biochem. 2018; 47(3):957-971.
Score: 0.040
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Breast cancer development and progression: Risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesis. Genes Dis. 2018 Jun; 5(2):77-106.
Score: 0.040
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Characterization of the essential role of bone morphogenetic protein 9 (BMP9) in osteogenic differentiation of mesenchymal stem cells (MSCs) through RNA interference. Genes Dis. 2018 Jun; 5(2):172-184.
Score: 0.040
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Establishment and functional characterization of the reversibly immortalized mouse glomerular podocytes (imPODs). Genes Dis. 2018 Jun; 5(2):137-149.
Score: 0.040
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The development of a sensitive fluorescent protein-based transcript reporter for high throughput screening of negative modulators of lncRNAs. Genes Dis. 2018 Mar; 5(1):62-74.
Score: 0.039
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3-D bioprinting technologies in tissue engineering and regenerative medicine: Current and future trends. Genes Dis. 2017 Dec; 4(4):185-195.
Score: 0.039
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Noncanonical Wnt signaling plays an important role in modulating canonical Wnt-regulated stemness, proliferation and terminal differentiation of hepatic progenitors. Oncotarget. 2017 Apr 18; 8(16):27105-27119.
Score: 0.037
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Notch Signaling Augments BMP9-Induced Bone Formation by Promoting the Osteogenesis-Angiogenesis Coupling Process in Mesenchymal Stem Cells (MSCs). Cell Physiol Biochem. 2017; 41(5):1905-1923.
Score: 0.037
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Anthelmintic mebendazole enhances cisplatin's effect on suppressing cell proliferation and promotes differentiation of head and neck squamous cell carcinoma (HNSCC). Oncotarget. 2017 Feb 21; 8(8):12968-12982.
Score: 0.037
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Wnt and BMP Signaling Crosstalk in Regulating Dental Stem Cells: Implications in Dental Tissue Engineering. Genes Dis. 2016 Dec; 3(4):263-276.
Score: 0.036
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A Blockade of IGF Signaling Sensitizes Human Ovarian Cancer Cells to the Anthelmintic Niclosamide-Induced Anti-Proliferative and Anticancer Activities. Cell Physiol Biochem. 2016; 39(3):871-88.
Score: 0.035
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Antibiotic monensin synergizes with EGFR inhibitors and oxaliplatin to suppress the proliferation of human ovarian cancer cells. Sci Rep. 2015 Dec 07; 5:17523.
Score: 0.034
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Multifaceted signaling regulators of chondrogenesis: Implications in cartilage regeneration and tissue engineering. Genes Dis. 2015 Dec; 2(4):307-327.
Score: 0.033
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Damage control: Harnessing prostaglandin E2 as a potential healing factor of tissue injuries. Genes Dis. 2015 Dec; 2(4):295-298.
Score: 0.033
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TqPCR: A Touchdown qPCR Assay with Significantly Improved Detection Sensitivity and Amplification Efficiency of SYBR Green qPCR. PLoS One. 2015; 10(7):e0132666.
Score: 0.033
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The Anthelmintic Drug Niclosamide Inhibits the Proliferative Activity of Human Osteosarcoma Cells by Targeting Multiple Signal Pathways. Curr Cancer Drug Targets. 2015; 15(8):726-38.
Score: 0.032
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Canonical Wnt signaling acts synergistically on BMP9-induced osteo/odontoblastic differentiation of stem cells of dental apical papilla (SCAPs). Biomaterials. 2015 Jan; 39:145-54.
Score: 0.031
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Functional characteristics of reversibly immortalized hepatic progenitor cells derived from mouse embryonic liver. Cell Physiol Biochem. 2014; 34(4):1318-38.
Score: 0.031
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Bone morphogenetic protein 2 inhibits the proliferation and growth of human colorectal cancer cells. Oncol Rep. 2014 Sep; 32(3):1013-20.
Score: 0.031
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Reversibly Immortalized Mouse Articular Chondrocytes Acquire Long-Term Proliferative Capability While Retaining Chondrogenic Phenotype. Cell Transplant. 2015; 24(6):1053-66.
Score: 0.030
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Characterization of constitutive promoters for piggyBac transposon-mediated stable transgene expression in mesenchymal stem cells (MSCs). PLoS One. 2014; 9(4):e94397.
Score: 0.030
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Bone morphogenetic protein-9 effectively induces osteo/odontoblastic differentiation of the reversibly immortalized stem cells of dental apical papilla. Stem Cells Dev. 2014 Jun 15; 23(12):1405-16.
Score: 0.030
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Targeting BMP9-promoted human osteosarcoma growth by inactivation of notch signaling. Curr Cancer Drug Targets. 2014; 14(3):274-85.
Score: 0.029
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Destabilization of heterologous proteins mediated by the GSK3ß phosphorylation domain of the ß-catenin protein. Cell Physiol Biochem. 2013; 32(5):1187-99.
Score: 0.029
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Endoplasmic reticulum (ER) stress inducible factor cysteine-rich with EGF-like domains 2 (Creld2) is an important mediator of BMP9-regulated osteogenic differentiation of mesenchymal stem cells. PLoS One. 2013; 8(9):e73086.
Score: 0.029
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Inhibition of histone deacetylases potentiates BMP9-induced osteogenic signaling in mouse mesenchymal stem cells. Cell Physiol Biochem. 2013; 32(2):486-98.
Score: 0.029
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Noggin resistance contributes to the potent osteogenic capability of BMP9 in mesenchymal stem cells. J Orthop Res. 2013 Nov; 31(11):1796-803.
Score: 0.029
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Cross-talk between EGF and BMP9 signalling pathways regulates the osteogenic differentiation of mesenchymal stem cells. J Cell Mol Med. 2013 Sep; 17(9):1160-72.
Score: 0.029
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Establishment and characterization of the reversibly immortalized mouse fetal heart progenitors. Int J Med Sci. 2013; 10(8):1035-46.
Score: 0.028
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Characterization of chondrocyte scaffold carriers for cell-based gene therapy in articular cartilage repair. J Biomed Mater Res A. 2013 Dec; 101(12):3542-50.
Score: 0.028
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BMP9-regulated angiogenic signaling plays an important role in the osteogenic differentiation of mesenchymal progenitor cells. J Cell Sci. 2013 Jan 15; 126(Pt 2):532-41.
Score: 0.027
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Ginsenoside Rg3 inhibits colorectal tumor growth through the down-regulation of Wnt/ß-catenin signaling. Int J Oncol. 2011 Feb; 38(2):437-45.
Score: 0.024
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Insulin-like growth factor 2 (IGF-2) potentiates BMP-9-induced osteogenic differentiation and bone formation. J Bone Miner Res. 2010 Nov; 25(11):2447-59.
Score: 0.024
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Retinoic acids potentiate BMP9-induced osteogenic differentiation of mesenchymal progenitor cells. PLoS One. 2010 Jul 30; 5(7):e11917.
Score: 0.023
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The CCN proteins: important signaling mediators in stem cell differentiation and tumorigenesis. Histol Histopathol. 2010 06; 25(6):795-806.
Score: 0.023
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Synergistic antitumor effect of the activated PPARgamma and retinoid receptors on human osteosarcoma. Clin Cancer Res. 2010 Apr 15; 16(8):2235-45.
Score: 0.023
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Therapeutic Implications of PPARgamma in Human Osteosarcoma. PPAR Res. 2010; 2010:956427.
Score: 0.023
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Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov; 29(10):1569-81.
Score: 0.022
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Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Sep 01; 108(1):295-303.
Score: 0.022
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BMP-14 gene therapy increases tendon tensile strength in a rat model of Achilles tendon injury. J Bone Joint Surg Am. 2007 Jun; 89(6):1315-20.
Score: 0.019