Yusuke Nakamura to Methylation
This is a "connection" page, showing publications Yusuke Nakamura has written about Methylation.
Connection Strength
1.694
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Dysregulation of protein methyltransferases in human cancer: An emerging target class for anticancer therapy. Cancer Sci. 2016 Apr; 107(4):377-84.
Score: 0.519
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Effects of SMYD2-mediated EML4-ALK methylation on the signaling pathway and growth in non-small-cell lung cancer cells. Cancer Sci. 2017 Jun; 108(6):1203-1209.
Score: 0.142
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WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer. Sci Rep. 2017 01 19; 7:40664.
Score: 0.139
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Critical roles of non-histone protein lysine methylation in human tumorigenesis. Nat Rev Cancer. 2015 Feb; 15(2):110-24.
Score: 0.121
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SMYD2-dependent HSP90 methylation promotes cancer cell proliferation by regulating the chaperone complex formation. Cancer Lett. 2014 Aug 28; 351(1):126-33.
Score: 0.115
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Lysyl 5-hydroxylation, a novel histone modification, by Jumonji domain containing 6 (JMJD6). J Biol Chem. 2013 Mar 01; 288(9):6053-62.
Score: 0.105
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The role of protein methyltransferases as potential novel therapeutic targets in squamous cell carcinoma of the head and neck. Oral Oncol. 2018 06; 81:100-108.
Score: 0.038
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Critical roles of protein methyltransferases and demethylases in the regulation of embryonic stem cell fate. Epigenetics. 2017; 12(12):1015-1027.
Score: 0.037
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Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization. Cancer Med. 2017 Jul; 6(7):1665-1672.
Score: 0.036
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SMYD3-mediated lysine methylation in the PH domain is critical for activation of AKT1. Oncotarget. 2016 Nov 15; 7(46):75023-75037.
Score: 0.034
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PRMT1 promotes mitosis of cancer cells through arginine methylation of INCENP. Oncotarget. 2015 Nov 03; 6(34):35173-82.
Score: 0.032
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PRMT6 increases cytoplasmic localization of p21CDKN1A in cancer cells through arginine methylation and makes more resistant to cytotoxic agents. Oncotarget. 2015 Oct 13; 6(31):30957-67.
Score: 0.032
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SUV39H2 methylates and stabilizes LSD1 by inhibiting polyubiquitination in human cancer cells. Oncotarget. 2015 Jul 10; 6(19):16939-50.
Score: 0.031
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The NSD family of protein methyltransferases in human cancer. Epigenomics. 2015 Aug; 7(5):863-74.
Score: 0.031
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Dysregulation of AKT Pathway by SMYD2-Mediated Lysine Methylation on PTEN. Neoplasia. 2015 Apr; 17(4):367-73.
Score: 0.031
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Critical role of lysine 134 methylation on histone H2AX for ?-H2AX production and DNA repair. Nat Commun. 2014 Dec 09; 5:5691.
Score: 0.030
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WHSC1 promotes oncogenesis through regulation of NIMA-related kinase-7 in squamous cell carcinoma of the head and neck. Mol Cancer Res. 2015 Feb; 13(2):293-304.
Score: 0.030
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The histone methyltransferase SMYD2 methylates PARP1 and promotes poly(ADP-ribosyl)ation activity in cancer cells. Neoplasia. 2014 Mar; 16(3):257-64, 264.e2.
Score: 0.029
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RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylation. Neoplasia. 2012 Jun; 14(6):476-86.
Score: 0.025
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Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression. Cancer Res. 2012 Jul 01; 72(13):3217-27.
Score: 0.025
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Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B. Nat Commun. 2012; 3:1072.
Score: 0.024
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The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene. Int J Cancer. 2012 Aug 01; 131(3):E179-89.
Score: 0.024
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Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway. Neoplasia. 2011 Oct; 13(10):887-98.
Score: 0.024
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Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells. Cancer Res. 2011 Feb 01; 71(3):655-60.
Score: 0.023
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The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3. Cancer Res. 2007 Nov 15; 67(22):10759-65.
Score: 0.018