"Methylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Addition of methyl groups. In histo-chemistry methylation is used to esterify carboxyl groups and remove sulfate groups by treating tissue sections with hot methanol in the presence of hydrochloric acid. (From Stedman, 25th ed)
| Descriptor ID |
D008745
|
| MeSH Number(s) |
G02.111.035.538 G02.607.094.538 G03.059.538
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Methylation".
Below are MeSH descriptors whose meaning is more specific than "Methylation".
This graph shows the total number of publications written about "Methylation" by people in this website by year, and whether "Methylation" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 6 | 6 |
| 2006 | 0 | 6 | 6 |
| 2007 | 3 | 5 | 8 |
| 2008 | 0 | 4 | 4 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 13 | 13 |
| 2011 | 0 | 10 | 10 |
| 2012 | 0 | 12 | 12 |
| 2013 | 0 | 12 | 12 |
| 2014 | 0 | 9 | 9 |
| 2015 | 0 | 16 | 16 |
| 2016 | 1 | 14 | 15 |
| 2017 | 0 | 13 | 13 |
| 2018 | 0 | 20 | 20 |
| 2019 | 1 | 13 | 14 |
| 2020 | 0 | 10 | 10 |
| 2021 | 0 | 7 | 7 |
| 2022 | 0 | 7 | 7 |
| 2023 | 0 | 11 | 11 |
| 2024 | 0 | 11 | 11 |
| 2025 | 0 | 5 | 5 |
| 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "Methylation" by people in Profiles.
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m6A mRNA methylation regulates pancreatic a-cell plasticity. Nat Metab. 2026 Sep; 8(9):1948-1970.
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YTHDF2 regulates self non-coding RNA metabolism to control inflammation and tumorigenesis. Nat Commun. 2025 Nov 12; 16(1):9946.
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m6A mRNA methylation decorates genes involved in fibrinogen synthesis to regulate liver regeneration in mice. Am J Physiol Gastrointest Liver Physiol. 2025 11 01; 329(5):G614-G627.
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NNMT inhibition in cancer-associated fibroblasts restores antitumour immunity. Nature. 2025 09; 645(8082):1051-1059.
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SSB cooperates with METTL16-mediated m6A RNA methylation to promote chemoresistance in colorectal cancer cells. Cell Rep. 2025 Jul 22; 44(7):115926.
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Endotoxin-induced m6A RNA methylation landscape in lung endothelial cells: role of METTL3 in regulating inflammation and injury during acute lung injury. Biochim Biophys Acta Mol Basis Dis. 2025 08; 1871(6):167907.
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Central control of dynamic gene circuits governs T cell rest and activation. Nature. 2025 01; 637(8047):930-939.
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Post-transcriptional methylation of mitochondrial-tRNA differentially contributes to mitochondrial pathology. Nat Commun. 2024 10 18; 15(1):9008.
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m6A mRNA methylation by METTL14 regulates early pancreatic cell differentiation. EMBO J. 2024 Nov; 43(22):5445-5468.
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m6A mRNA methylation in brown fat regulates systemic insulin sensitivity via an inter-organ prostaglandin signaling axis independent of UCP1. Cell Metab. 2024 Oct 01; 36(10):2207-2227.e9.