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Connection

Tobin Sosnick to Thermodynamics

This is a "connection" page, showing publications Tobin Sosnick has written about Thermodynamics.
Connection Strength

3.422
  1. Context and force field dependence of the loss of protein backbone entropy upon folding using realistic denatured and native state ensembles. J Am Chem Soc. 2012 Sep 26; 134(38):15929-36.
    View in: PubMed
    Score: 0.354
  2. Practical Tips for the Application of HDX-MS to Membrane Proteins, Biomolecular Condensates, and Weak Protein Binders. J Am Soc Mass Spectrom. 2025 Aug 06; 36(8):1575-1587.
    View in: PubMed
    Score: 0.214
  3. Collapse and Protein Folding: Should We Be Surprised That Biothermodynamics Works So Well? Annu Rev Biophys. 2025 05; 54(1):17-34.
    View in: PubMed
    Score: 0.207
  4. HDX-MS finds that partial unfolding with sequential domain activation controls condensation of a cellular stress marker. Proc Natl Acad Sci U S A. 2024 Mar 26; 121(13):e2321606121.
    View in: PubMed
    Score: 0.197
  5. Contribution of hydrogen bonding to protein stability estimated from isotope effects. Biochemistry. 2002 Feb 19; 41(7):2120-9.
    View in: PubMed
    Score: 0.170
  6. Engineered Metal-Binding Sites to Probe Protein Folding Transition States: Psi Analysis. Methods Mol Biol. 2022; 2376:31-63.
    View in: PubMed
    Score: 0.169
  7. Trajectory-based training enables protein simulations with accurate folding and Boltzmann ensembles in cpu-hours. PLoS Comput Biol. 2018 12; 14(12):e1006578.
    View in: PubMed
    Score: 0.137
  8. Accurate calculation of side chain packing and free energy with applications to protein molecular dynamics. PLoS Comput Biol. 2018 12; 14(12):e1006342.
    View in: PubMed
    Score: 0.137
  9. A Membrane Burial Potential with H-Bonds and Applications to Curved Membranes and Fast Simulations. Biophys J. 2018 11 20; 115(10):1872-1884.
    View in: PubMed
    Score: 0.135
  10. Cooperative folding near the downhill limit determined with amino acid resolution by hydrogen exchange. Proc Natl Acad Sci U S A. 2016 Apr 26; 113(17):4747-52.
    View in: PubMed
    Score: 0.113
  11. Even with nonnative interactions, the updated folding transition states of the homologs Proteins G & L are extensive and similar. Proc Natl Acad Sci U S A. 2015 Jul 07; 112(27):8302-7.
    View in: PubMed
    Score: 0.107
  12. Protein vivisection reveals elusive intermediates in folding. J Mol Biol. 2010 Apr 02; 397(3):777-88.
    View in: PubMed
    Score: 0.074
  13. Metal binding kinetics of bi-histidine sites used in psi analysis: evidence of high-energy protein folding intermediates. Biochemistry. 2009 Apr 07; 48(13):2950-9.
    View in: PubMed
    Score: 0.070
  14. Quantifying the structural requirements of the folding transition state of protein A and other systems. J Mol Biol. 2008 Sep 19; 381(5):1362-81.
    View in: PubMed
    Score: 0.066
  15. Small proteins fold through transition states with native-like topologies. J Mol Biol. 2006 Aug 25; 361(4):755-70.
    View in: PubMed
    Score: 0.058
  16. Characterizing the protein folding transition state using psi analysis. Chem Rev. 2006 May; 106(5):1862-76.
    View in: PubMed
    Score: 0.057
  17. Structure of a folding intermediate reveals the interplay between core and peripheral elements in RNA folding. J Mol Biol. 2005 Sep 23; 352(3):712-22.
    View in: PubMed
    Score: 0.055
  18. Differences in the folding transition state of ubiquitin indicated by phi and psi analyses. Proc Natl Acad Sci U S A. 2004 Dec 14; 101(50):17377-82.
    View in: PubMed
    Score: 0.052
  19. Barrier-limited, microsecond folding of a stable protein measured with hydrogen exchange: Implications for downhill folding. Proc Natl Acad Sci U S A. 2004 Nov 02; 101(44):15639-44.
    View in: PubMed
    Score: 0.051
  20. Early collapse is not an obligate step in protein folding. J Mol Biol. 2004 Apr 23; 338(2):369-82.
    View in: PubMed
    Score: 0.049
  21. Discerning the structure and energy of multiple transition states in protein folding using psi-analysis. J Mol Biol. 2004 Mar 19; 337(2):463-75.
    View in: PubMed
    Score: 0.049
  22. Fast and slow intermediate accumulation and the initial barrier mechanism in protein folding. J Mol Biol. 2002 Nov 22; 324(2):359-71.
    View in: PubMed
    Score: 0.045
  23. Getting hotter with RNA. Nat Struct Biol. 2002 Nov; 9(11):795-6.
    View in: PubMed
    Score: 0.045
  24. Dynamics of hydrogen bond desolvation in protein folding. J Mol Biol. 2002 Aug 23; 321(4):659-75.
    View in: PubMed
    Score: 0.044
  25. Understanding protein hydrogen bond formation with kinetic H/D amide isotope effects. Nat Struct Biol. 2002 Jun; 9(6):458-63.
    View in: PubMed
    Score: 0.043
  26. Engineered metal binding sites map the heterogeneous folding landscape of a coiled coil. Nat Struct Biol. 2001 Dec; 8(12):1042-7.
    View in: PubMed
    Score: 0.042
  27. Characterization of tertiary folding of RNA by circular dichroism and urea. Curr Protoc Nucleic Acid Chem. 2001 May; Chapter 11:Unit 11.5.
    View in: PubMed
    Score: 0.040
  28. The thermodynamic origin of the stability of a thermophilic ribozyme. Proc Natl Acad Sci U S A. 2001 Apr 10; 98(8):4355-60.
    View in: PubMed
    Score: 0.040
  29. Distinguishing between two-state and three-state models for ubiquitin folding. Biochemistry. 2000 Sep 26; 39(38):11696-701.
    View in: PubMed
    Score: 0.039
  30. Mg2+-dependent compaction and folding of yeast tRNAPhe and the catalytic domain of the B. subtilis RNase P RNA determined by small-angle X-ray scattering. Biochemistry. 2000 Sep 12; 39(36):11107-13.
    View in: PubMed
    Score: 0.038
  31. D/H amide kinetic isotope effects reveal when hydrogen bonds form during protein folding. Nat Struct Biol. 2000 Jan; 7(1):62-71.
    View in: PubMed
    Score: 0.037
  32. A thermodynamic framework and cooperativity in the tertiary folding of a Mg2+-dependent ribozyme. Biochemistry. 1999 Dec 21; 38(51):16840-6.
    View in: PubMed
    Score: 0.037
  33. Mg2+-dependent folding of a large ribozyme without kinetic traps. Nat Struct Biol. 1999 Dec; 6(12):1091-5.
    View in: PubMed
    Score: 0.036
  34. Transition state heterogeneity in GCN4 coiled coil folding studied by using multisite mutations and crosslinking. Proc Natl Acad Sci U S A. 1999 Sep 14; 96(19):10699-704.
    View in: PubMed
    Score: 0.036
  35. Pathway modulation, circular permutation and rapid RNA folding under kinetic control. J Mol Biol. 1999 Feb 26; 286(3):721-31.
    View in: PubMed
    Score: 0.035
  36. Viscosity dependence of the folding kinetics of a dimeric and monomeric coiled coil. Biochemistry. 1999 Feb 23; 38(8):2601-9.
    View in: PubMed
    Score: 0.035
  37. Perplexing cooperative folding and stability of a low-sequence complexity, polyproline 2 protein lacking a hydrophobic core. Proc Natl Acad Sci U S A. 2017 02 28; 114(9):2241-2246.
    View in: PubMed
    Score: 0.030
  38. Protein minimization: downsizing through mutation. Proc Natl Acad Sci U S A. 1996 Jun 11; 93(12):5680-1.
    View in: PubMed
    Score: 0.029
  39. Molecular collapse: the rate-limiting step in two-state cytochrome c folding. Proteins. 1996 Apr; 24(4):413-26.
    View in: PubMed
    Score: 0.028
  40. The role of helix formation in the folding of a fully alpha-helical coiled coil. Proteins. 1996 Apr; 24(4):427-32.
    View in: PubMed
    Score: 0.028
  41. Ionic strength independence of charge distributions in solvation of biomolecules. J Chem Phys. 2014 Dec 14; 141(22):22D503.
    View in: PubMed
    Score: 0.026
  42. Denatured states of ribonuclease A have compact dimensions and residual secondary structure. Biochemistry. 1992 Sep 08; 31(35):8329-35.
    View in: PubMed
    Score: 0.022
  43. Principal determinants leading to transition state formation of a protein-protein complex, orientation trumps side-chain interactions. Proc Natl Acad Sci U S A. 2009 Feb 24; 106(8):2559-64.
    View in: PubMed
    Score: 0.017
  44. Single-molecule nonequilibrium periodic Mg2+-concentration jump experiments reveal details of the early folding pathways of a large RNA. Proc Natl Acad Sci U S A. 2008 May 06; 105(18):6602-7.
    View in: PubMed
    Score: 0.016
  45. The highly cooperative folding of small naturally occurring proteins is likely the result of natural selection. Cell. 2007 Feb 09; 128(3):613-24.
    View in: PubMed
    Score: 0.015
  46. Minimalist representations and the importance of nearest neighbor effects in protein folding simulations. J Mol Biol. 2006 Nov 03; 363(4):835-57.
    View in: PubMed
    Score: 0.015
  47. On the precision of experimentally determined protein folding rates and phi-values. Protein Sci. 2006 Mar; 15(3):553-63.
    View in: PubMed
    Score: 0.014
  48. Random-coil behavior and the dimensions of chemically unfolded proteins. Proc Natl Acad Sci U S A. 2004 Aug 24; 101(34):12491-6.
    View in: PubMed
    Score: 0.013
  49. Stepwise conversion of a mesophilic to a thermophilic ribozyme. J Mol Biol. 2003 Jul 04; 330(2):177-83.
    View in: PubMed
    Score: 0.012
  50. Large-scale context in protein folding: villin headpiece. Biochemistry. 2003 Jan 28; 42(3):664-71.
    View in: PubMed
    Score: 0.011
  51. Modular construction of a tertiary RNA structure: the specificity domain of the Bacillus subtilis RNase P RNA. Biochemistry. 2001 Sep 18; 40(37):11202-10.
    View in: PubMed
    Score: 0.010
  52. Altering the intermediate in the equilibrium folding of unmodified yeast tRNAPhe with monovalent and divalent cations. Biochemistry. 2001 Mar 27; 40(12):3629-38.
    View in: PubMed
    Score: 0.010
  53. Applicability of urea in the thermodynamic analysis of secondary and tertiary RNA folding. Biochemistry. 1999 Dec 21; 38(51):16831-9.
    View in: PubMed
    Score: 0.009
  54. Protein folding intermediates: native-state hydrogen exchange. Science. 1995 Jul 14; 269(5221):192-7.
    View in: PubMed
    Score: 0.007
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.