Louis Philipson to Insulin
This is a "connection" page, showing publications Louis Philipson has written about Insulin.
Connection Strength
5.058
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Insulin dosing in pediatric diabetic ketoacidosis: where to start? JAMA. 2015 Jun 09; 313(22):2274-5.
Score: 0.359
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Ion channels and regulation of insulin secretion in human ß-cells: a computational systems analysis. Islets. 2013 Jan-Feb; 5(1):1-15.
Score: 0.304
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SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretion. Am J Physiol Endocrinol Metab. 2012 Mar 15; 302(6):E714-23.
Score: 0.284
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Coupling of metabolic, second messenger pathways and insulin granule dynamics in pancreatic beta-cells: a computational analysis. Prog Biophys Mol Biol. 2011 Nov; 107(2):293-303.
Score: 0.277
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Glucose-induced ERM protein activation and translocation regulates insulin secretion. Am J Physiol Endocrinol Metab. 2010 Nov; 299(5):E772-85.
Score: 0.258
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In vitro processing and secretion of mutant insulin proteins that cause permanent neonatal diabetes. Am J Physiol Endocrinol Metab. 2010 Mar; 298(3):E403-10.
Score: 0.245
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Action potentials and insulin secretion: new insights into the role of Kv channels. Diabetes Obes Metab. 2007 Nov; 9 Suppl 2:89-98.
Score: 0.212
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5-amino-imidazole carboxamide riboside acutely potentiates glucose-stimulated insulin secretion from mouse pancreatic islets by KATP channel-dependent and -independent pathways. Biochem Biophys Res Commun. 2005 May 20; 330(4):1073-9.
Score: 0.179
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Does the glucose-dependent insulin secretion mechanism itself cause oxidative stress in pancreatic beta-cells? Diabetes. 2004 Aug; 53(8):1942-8.
Score: 0.169
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Direct imaging shows that insulin granule exocytosis occurs by complete vesicle fusion. Proc Natl Acad Sci U S A. 2004 Jun 22; 101(25):9266-71.
Score: 0.168
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beta-Agonists and metabolism. J Allergy Clin Immunol. 2002 Dec; 110(6 Suppl):S313-7.
Score: 0.151
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TRP genes: candidates for nonselective cation channels and store-operated channels in insulin-secreting cells. Diabetes. 2002 Feb; 51 Suppl 1:S183-9.
Score: 0.142
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External Validation of the Newly Developed BETA-2 Scoring System for Pancreatic Islet Graft Function Assessment. Transplant Proc. 2017 Dec; 49(10):2340-2346.
Score: 0.107
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Deletion of Protein Kinase D1 in Pancreatic ß-Cells Impairs Insulin Secretion in High-Fat Diet-Fed Mice. Diabetes. 2018 01; 67(1):71-77.
Score: 0.106
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Preservation of Reduced Numbers of Insulin-Positive Cells in Sulfonylurea-Unresponsive KCNJ11-Related Diabetes. J Clin Endocrinol Metab. 2017 01 01; 102(1):1-5.
Score: 0.100
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Resting beta-cells - A functional reserve? Diabetes Metab. 2016 Jun; 42(3):157-61.
Score: 0.094
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TCF1 links GIPR signaling to the control of beta cell function and survival. Nat Med. 2016 Jan; 22(1):84-90.
Score: 0.093
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Dynamin 2 regulates biphasic insulin secretion and plasma glucose homeostasis. J Clin Invest. 2015 Nov 02; 125(11):4026-41.
Score: 0.092
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Loss of Liver Kinase B1 (LKB1) in Beta Cells Enhances Glucose-stimulated Insulin Secretion Despite Profound Mitochondrial Defects. J Biol Chem. 2015 Aug 21; 290(34):20934-20946.
Score: 0.090
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Functional role of serotonin in insulin secretion in a diet-induced insulin-resistant state. Endocrinology. 2015 Feb; 156(2):444-52.
Score: 0.087
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Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic ß cells. Proc Natl Acad Sci U S A. 2014 Jun 03; 111(22):E2319-28.
Score: 0.083
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Intracellular transport of insulin granules is a subordinated random walk. Proc Natl Acad Sci U S A. 2013 Mar 26; 110(13):4911-6.
Score: 0.077
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ß-Cell-specific protein kinase A activation enhances the efficiency of glucose control by increasing acute-phase insulin secretion. Diabetes. 2013 May; 62(5):1527-36.
Score: 0.076
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Clinical and molecular genetics of neonatal diabetes due to mutations in the insulin gene. Rev Endocr Metab Disord. 2010 Sep; 11(3):205-15.
Score: 0.065
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Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes. Nature. 2010 Jul 29; 466(7306):627-31.
Score: 0.064
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Neonatal diabetes mellitus: a model for personalized medicine. Trends Endocrinol Metab. 2010 Aug; 21(8):464-72.
Score: 0.063
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Update in neonatal diabetes. Curr Opin Endocrinol Diabetes Obes. 2010 Feb; 17(1):13-9.
Score: 0.062
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A brief perspective on insulin production. Diabetes Obes Metab. 2009 Nov; 11 Suppl 4:189-96.
Score: 0.061
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The granular chloride channel ClC-3 is permissive for insulin secretion. Cell Metab. 2009 Oct; 10(4):316-23.
Score: 0.061
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Diagnosis and treatment of neonatal diabetes: a United States experience. Pediatr Diabetes. 2008 Oct; 9(5):450-9.
Score: 0.056
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When BAD is good for beta cells. Cell Metab. 2008 Apr; 7(4):280-1.
Score: 0.055
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Mutations in the insulin gene can cause MODY and autoantibody-negative type 1 diabetes. Diabetes. 2008 Apr; 57(4):1131-5.
Score: 0.054
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Insulin mutation screening in 1,044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood. Diabetes. 2008 Apr; 57(4):1034-42.
Score: 0.054
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Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice. Am J Physiol Endocrinol Metab. 2008 Feb; 294(2):E217-29.
Score: 0.053
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Insulin gene mutations as a cause of permanent neonatal diabetes. Proc Natl Acad Sci U S A. 2007 Sep 18; 104(38):15040-4.
Score: 0.053
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Kv2.1 ablation alters glucose-induced islet electrical activity, enhancing insulin secretion. Cell Metab. 2007 Sep; 6(3):229-35.
Score: 0.052
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Reactive species and early manifestation of insulin resistance in type 2 diabetes. Diabetes Obes Metab. 2006 Mar; 8(2):136-45.
Score: 0.047
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Intragranular targeting of syncollin, but not a syncollinGFP chimera, inhibits regulated insulin exocytosis in pancreatic beta-cells. J Endocrinol. 2005 Apr; 185(1):57-67.
Score: 0.044
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Exenatide extended release in patients with type 1 diabetes with and without residual insulin production. Diabetes Obes Metab. 2020 11; 22(11):2045-2054.
Score: 0.032
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Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion. Am J Physiol Endocrinol Metab. 2000 Feb; 278(2):E340-51.
Score: 0.031
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Beta-cell ion channels: keys to endodermal excitability. Horm Metab Res. 1999 Aug; 31(8):455-61.
Score: 0.030
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Management and pregnancy outcomes of women with GCK-MODY enrolled in the US Monogenic Diabetes Registry. Acta Diabetol. 2019 Apr; 56(4):405-411.
Score: 0.029
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Defective pancreatic beta-cell glycolytic signaling in hepatocyte nuclear factor-1alpha-deficient mice. J Biol Chem. 1998 Sep 18; 273(38):24457-64.
Score: 0.028
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Apoptosis in insulin-secreting cells. Evidence for the role of intracellular Ca2+ stores and arachidonic acid metabolism. J Clin Invest. 1998 Apr 15; 101(8):1623-32.
Score: 0.027
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Comparative evaluation of simple indices using a single fasting blood sample to estimate beta cell function after islet transplantation. Am J Transplant. 2018 04; 18(4):990-997.
Score: 0.027
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K+ channels: generating excitement in pancreatic beta-cells. Diabetes. 1996 Jul; 45(7):845-53.
Score: 0.024
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A Transient Metabolic Recovery from Early Life Glucose Intolerance in Cystic Fibrosis Ferrets Occurs During Pancreatic Remodeling. Endocrinology. 2016 05; 157(5):1852-65.
Score: 0.024
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Pas de deux or more: the sulfonylurea receptor and K+ channels. Science. 1995 Apr 21; 268(5209):372-3.
Score: 0.022
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Delayed rectifier K+ channel overexpression in transgenic islets and beta-cells associated with impaired glucose responsiveness. J Biol Chem. 1994 Nov 11; 269(45):27787-90.
Score: 0.022
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The role of ß cell glucagon-like peptide-1 signaling in glucose regulation and response to diabetes drugs. Cell Metab. 2014 Jun 03; 19(6):1050-7.
Score: 0.021
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Quantifying insulin sensitivity and entero-insular responsiveness to hyper- and hypoglycemia in ferrets. PLoS One. 2014; 9(3):e90519.
Score: 0.021
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Lean versus obese diabetes mellitus patients in the United States minority population. J Diabetes Complications. 2014 Jul-Aug; 28(4):500-5.
Score: 0.020
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Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain. Diabetes. 2010 Dec; 59(12):3090-8.
Score: 0.016
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Tooth discoloration in patients with neonatal diabetes after transfer onto glibenclamide: a previously unreported side effect. Diabetes Care. 2009 Aug; 32(8):1428-30.
Score: 0.015
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Leptin deficiency and beta-cell dysfunction underlie type 2 diabetes in compound Akt knockout mice. Mol Cell Biol. 2009 Jun; 29(11):3151-62.
Score: 0.015
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The chemistrode: a droplet-based microfluidic device for stimulation and recording with high temporal, spatial, and chemical resolution. Proc Natl Acad Sci U S A. 2008 Nov 04; 105(44):16843-8.
Score: 0.014
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Functional MR microimaging of pancreatic beta-cell activation. Cell Transplant. 2006; 15(2):195-203.
Score: 0.012
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Efficient secretion and purification of human insulin-like growth factor I with a gene fusion vector in Staphylococci. Nucleic Acids Res. 1985 Feb 25; 13(4):1151-62.
Score: 0.011
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Insulin secretory deficiency and glucose intolerance in Rab3A null mice. J Biol Chem. 2003 Mar 14; 278(11):9715-21.
Score: 0.009
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Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism. Diabetes. 2001 Nov; 50(11):2472-80.
Score: 0.009
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Defective glucose-dependent endoplasmic reticulum Ca2+ sequestration in diabetic mouse islets of Langerhans. J Biol Chem. 1994 Jul 15; 269(28):18279-82.
Score: 0.005