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Issam Awad to Tissue Plasminogen Activator

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This is a "connection" page, showing publications Issam Awad has written about Tissue Plasminogen Activator.
Issam Awad
Connection Strength
4.726
Tissue Plasminogen Activator
  1. In Reply: Surgical Performance Determines Functional Outcome Benefit in the Minimally Invasive Surgery Plus Recombinant Tissue Plasminogen Activator for Intracerebral Hemorrhage Evacuation (MISTIE) Procedure. Neurosurgery. 2020 04 01; 86(4):E411.
    View in: PubMed
    Score: 0.568
  2. Surgical Performance Determines Functional Outcome Benefit in the Minimally Invasive Surgery Plus Recombinant Tissue Plasminogen Activator for Intracerebral Hemorrhage Evacuation (MISTIE) Procedure. Neurosurgery. 2019 06 01; 84(6):1157-1168.
    View in: PubMed
    Score: 0.536
  3. Symptomatic Hemorrhagic Complications in Clot Lysis: Evaluation of Accelerated Resolution of Intraventricular Hemorrhage Phase III Clinical Trial (CLEAR III): A Posthoc Root-Cause Analysis. Neurosurgery. 2018 12 01; 83(6):1260-1268.
    View in: PubMed
    Score: 0.518
  4. Surgical Performance in Minimally Invasive Surgery Plus Recombinant Tissue Plasminogen Activator for Intracerebral Hemorrhage Evacuation Phase III Clinical Trial. Neurosurgery. 2017 Nov 01; 81(5):860-866.
    View in: PubMed
    Score: 0.480
  5. Intracerebral Hemorrhage: Keep It Simple. Stroke. 2024 12; 55(12):2942-2945.
    View in: PubMed
    Score: 0.195
  6. Does stereotactic thrombolysis with alteplase for intracerebral haemorrhage alter intraventricular haematoma volume? A secondary analysis of the MISTIE-III trial. J Neurol Neurosurg Psychiatry. 2024 Sep 17; 95(10):892-898.
    View in: PubMed
    Score: 0.193
  7. Mechanistic Evaluation of Diffusion Weighted Hyperintense Lesions After Large Spontaneous Intracerebral Hemorrhage: A Subgroup Analysis of MISTIE III. Neurocrit Care. 2024 Jun; 40(3):1140-1150.
    View in: PubMed
    Score: 0.183
  8. Minimally Invasive Surgery With Thrombolysis for Intracerebral Hemorrhage Evacuation: Bayesian Reanalysis of a Randomized Controlled Trial. Neurology. 2023 10 17; 101(16):e1614-e1622.
    View in: PubMed
    Score: 0.180
  9. One-Year Outcome Trajectories and Factors Associated with Functional Recovery Among Survivors of Intracerebral and Intraventricular Hemorrhage With Initial Severe Disability. JAMA Neurol. 2022 09 01; 79(9):856-868.
    View in: PubMed
    Score: 0.168
  10. Association Between Intraventricular Alteplase Use and Parenchymal Hematoma Volume in Patients With Spontaneous Intracerebral Hemorrhage and Intraventricular Hemorrhage. JAMA Netw Open. 2021 12 01; 4(12):e2135773.
    View in: PubMed
    Score: 0.159
  11. Thrombolysis for Evacuation of Intracerebral and Intraventricular Hemorrhage: A Guide to Surgical Protocols With Practical Lessons Learned From the MISTIE and CLEAR Trials. Oper Neurosurg (Hagerstown). 2020 12 15; 20(1):98-108.
    View in: PubMed
    Score: 0.149
  12. Intracranial Hypertension and Cerebral Perfusion Pressure Insults in Adult Hypertensive Intraventricular Hemorrhage: Occurrence and Associations With Outcome. Crit Care Med. 2019 08; 47(8):1125-1134.
    View in: PubMed
    Score: 0.136
  13. A randomized 500-subject open-label phase 3 clinical trial of minimally invasive surgery plus alteplase in intracerebral hemorrhage evacuation (MISTIE III). Int J Stroke. 2019 07; 14(5):548-554.
    View in: PubMed
    Score: 0.133
  14. Thrombolytic removal of intraventricular haemorrhage in treatment of severe stroke: results of the randomised, multicentre, multiregion, placebo-controlled CLEAR III trial. Lancet. 2017 02 11; 389(10069):603-611.
    View in: PubMed
    Score: 0.114
  15. Safety and efficacy of minimally invasive surgery plus alteplase in intracerebral haemorrhage evacuation (MISTIE): a randomised, controlled, open-label, phase 2 trial. Lancet Neurol. 2016 Nov; 15(12):1228-1237.
    View in: PubMed
    Score: 0.112
  16. Bleeding and infection with external ventricular drainage: a systematic review in comparison with adjudicated adverse events in the ongoing Clot Lysis Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III (CLEAR-III IHV) trial. Neurosurgery. 2015 Mar; 76(3):291-300; discussion 301.
    View in: PubMed
    Score: 0.100
  17. A multicenter, randomized, double-blinded, placebo-controlled phase III study of Clot Lysis Evaluation of Accelerated Resolution of Intraventricular Hemorrhage (CLEAR III). Int J Stroke. 2014 Jun; 9(4):536-42.
    View in: PubMed
    Score: 0.090
  18. Minimally invasive surgery plus recombinant tissue-type plasminogen activator for intracerebral hemorrhage evacuation decreases perihematomal edema. Stroke. 2013 Mar; 44(3):627-34.
    View in: PubMed
    Score: 0.087
  19. Resolution of intraventricular hemorrhage varies by ventricular region and dose of intraventricular thrombolytic: the Clot Lysis: Evaluating Accelerated Resolution of IVH (CLEAR IVH) program. Stroke. 2012 Jun; 43(6):1666-8.
    View in: PubMed
    Score: 0.082
  20. Low-dose recombinant tissue-type plasminogen activator enhances clot resolution in brain hemorrhage: the intraventricular hemorrhage thrombolysis trial. Stroke. 2011 Nov; 42(11):3009-16.
    View in: PubMed
    Score: 0.078
  21. Intraventricular hemorrhage secondary to intranidal aneurysm rupture-successful management by arteriovenous malformation embolization followed by intraventricular tissue plasminogen activator: case report. Neurosurgery. 2011 Feb; 68(2):E581-6; discussion E586.
    View in: PubMed
    Score: 0.075
  22. Preliminary report of the clot lysis evaluating accelerated resolution of intraventricular hemorrhage (CLEAR-IVH) clinical trial. Acta Neurochir Suppl. 2008; 105:217-20.
    View in: PubMed
    Score: 0.061
  23. Impact of Minimally Invasive Surgery on Midline Shift and Outcomes in Large Supratentorial Spontaneous Intracerebral Hemorrhage: Post Hoc Analysis of MISTIE III. Neurocrit Care. 2026 Feb; 44(1):261-272.
    View in: PubMed
    Score: 0.052
  24. Cerebral small vessel disease modifies outcomes after minimally invasive surgery for intracerebral haemorrhage. Stroke Vasc Neurol. 2024 08 27; 9(4):446-456.
    View in: PubMed
    Score: 0.048
  25. Association Between Hematoma Volume and Risk of Subsequent Ischemic Stroke: A MISTIE III and ATACH-2 Analysis. Stroke. 2024 03; 55(3):541-547.
    View in: PubMed
    Score: 0.046
  26. Bayesian deep learning outperforms clinical trial estimators of intracerebral and intraventricular hemorrhage volume. J Neuroimaging. 2022 09; 32(5):968-976.
    View in: PubMed
    Score: 0.041
  27. A Pooled Analysis of Diffusion-Weighted Imaging Lesions in Patients With Acute Intracerebral Hemorrhage. JAMA Neurol. 2020 Nov 01; 77(11):1390-1397.
    View in: PubMed
    Score: 0.037
  28. Primary intraventricular hemorrhage outcomes in the CLEAR III trial. Int J Stroke. 2020 10; 15(8):872-880.
    View in: PubMed
    Score: 0.035
  29. Permanent CSF shunting after intraventricular hemorrhage in the CLEAR III trial. Neurology. 2017 Jul 25; 89(4):355-362.
    View in: PubMed
    Score: 0.029
  30. The Modified Graeb Score: an enhanced tool for intraventricular hemorrhage measurement and prediction of functional outcome. Stroke. 2013 Mar; 44(3):635-41.
    View in: PubMed
    Score: 0.022
  31. Occurrence and impact of intracranial pressure elevation during treatment of severe intraventricular hemorrhage. Crit Care Med. 2012 May; 40(5):1601-8.
    View in: PubMed
    Score: 0.021
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