Geoffrey Greene to Ligands
This is a "connection" page, showing publications Geoffrey Greene has written about Ligands.
Connection Strength
1.074
-
Ligand control of coregulator recruitment to nuclear receptors. Annu Rev Physiol. 2005; 67:309-33.
Score: 0.232
-
NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses. Nat Chem Biol. 2008 Apr; 4(4):241-7.
Score: 0.072
-
An estrogen receptor-alpha knock-in mutation provides evidence of ligand-independent signaling and allows modulation of ligand-induced pathways in vivo. Endocrinology. 2008 Jun; 149(6):2970-9.
Score: 0.072
-
Structural plasticity in the oestrogen receptor ligand-binding domain. EMBO Rep. 2007 Jun; 8(6):563-8.
Score: 0.068
-
Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity. J Biol Chem. 2006 Jun 30; 281(26):17909-19.
Score: 0.063
-
Structural basis for an unexpected mode of SERM-mediated ER antagonism. Mol Cell. 2005 May 13; 18(4):413-24.
Score: 0.059
-
Allosteric control of ligand selectivity between estrogen receptors alpha and beta: implications for other nuclear receptors. Mol Cell. 2004 Feb 13; 13(3):317-27.
Score: 0.054
-
Nuclear receptor ligands and cofactor recruitment: is there a coactivator "on deck"? Mol Cell. 2003 Apr; 11(4):850-1.
Score: 0.051
-
Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife. 2022 05 16; 11.
Score: 0.048
-
Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism. Nat Struct Biol. 2002 May; 9(5):359-64.
Score: 0.048
-
Defining the Energetic Basis for a Conformational Switch Mediating Ligand-Independent Activation of Mutant Estrogen Receptors in Breast Cancer. Mol Cancer Res. 2021 09; 19(9):1559-1570.
Score: 0.045
-
Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer. Mol Cancer Ther. 2021 01; 20(1):11-25.
Score: 0.043
-
Oestrogen receptor function at classical and alternative response elements. Novartis Found Symp. 2000; 230:20-6; discussion 27-40.
Score: 0.041
-
The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells. Elife. 2018 11 29; 7.
Score: 0.038
-
Antagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain. ACS Chem Biol. 2018 12 21; 13(12):3374-3384.
Score: 0.038
-
ESR1 ligand-binding domain mutations in hormone-resistant breast cancer. Nat Genet. 2013 Dec; 45(12):1439-45.
Score: 0.027
-
Characterization of the ovarian and reproductive abnormalities in prepubertal and adult estrogen non-responsive estrogen receptor alpha knock-in (ENERKI) mice. Steroids. 2009 Nov; 74(12):913-9.
Score: 0.020
-
Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands. Chem Biol. 2007 Jun; 14(6):659-69.
Score: 0.017
-
Structure-guided optimization of estrogen receptor binding affinity and antagonist potency of pyrazolopyrimidines with basic side chains. J Med Chem. 2007 Jan 25; 50(2):399-403.
Score: 0.017
-
Analysis of the structural core of the human estrogen receptor ligand binding domain by selective proteolysis/mass spectrometric analysis. Biochemistry. 1995 Oct 03; 34(39):12605-15.
Score: 0.008
-
Ligand-modulated regulation of progesterone receptor messenger ribonucleic acid and protein in human breast cancer cell lines. Mol Endocrinol. 1988 Mar; 2(3):263-71.
Score: 0.005
-
Cellular progesterone receptor phosphorylation in response to ligands activating protein kinases. Biochem Biophys Res Commun. 1987 Aug 14; 146(3):1357-65.
Score: 0.004
-
Differences between estrogen- and antiestrogen-estrogen receptor complexes from human breast tumors identified with an antibody raised against the estrogen receptor. Cancer Res. 1984 Mar; 44(3):1012-8.
Score: 0.003