Christopher Rhodes to Diabetes Mellitus, Type 2
This is a "connection" page, showing publications Christopher Rhodes has written about Diabetes Mellitus, Type 2.
Connection Strength
1.706
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Pancreatic ß-Cell Adaptive Plasticity in Obesity Increases Insulin Production but Adversely Affects Secretory Function. Diabetes. 2016 Feb; 65(2):438-50.
Score: 0.245
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Insulin resistance and type 2 diabetes as allostatic responses to chronic nutrient excess. Cell Metab. 2026 Aug 04; 38(8):1540-1556.
Score: 0.130
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GLP-1R/GCGR dual agonism dissipates hepatic steatosis to restore insulin sensitivity and rescue pancreatic ß-cell function in obese male mice. Nat Commun. 2025 May 21; 16(1):4714.
Score: 0.120
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Type 2 diabetes-a matter of beta-cell life and death? Science. 2005 Jan 21; 307(5708):380-4.
Score: 0.118
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Pancreatic beta-cell growth and survival in the onset of type 2 diabetes: a role for protein kinase B in the Akt? Am J Physiol Endocrinol Metab. 2004 Aug; 287(2):E192-8.
Score: 0.114
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High Plasma Levels of Soluble Lectin-like Oxidized Low-Density Lipoprotein Receptor-1 Are Associated With Inflammation and Cardiometabolic Risk Profiles in Pediatric Overweight and Obesity. J Am Heart Assoc. 2023 02 07; 12(3):e8145.
Score: 0.102
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Pancreatic beta-cell growth and survival--a role in obesity-linked type 2 diabetes? Trends Mol Med. 2002 Aug; 8(8):375-84.
Score: 0.099
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Characterization of Signaling Pathways Associated with Pancreatic ß-cell Adaptive Flexibility in Compensation of Obesity-linked Diabetes in db/db Mice. Mol Cell Proteomics. 2020 06; 19(6):971-993.
Score: 0.084
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Proteomic Analysis of Restored Insulin Production and Trafficking in Obese Diabetic Mouse Pancreatic Islets Following Euglycemia. J Proteome Res. 2019 09 06; 18(9):3245-3258.
Score: 0.080
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Pancreatic ß-Cell Rest Replenishes Insulin Secretory Capacity and Attenuates Diabetes in an Extreme Model of Obese Type 2 Diabetes. Diabetes. 2019 01; 68(1):131-140.
Score: 0.076
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Neurturin and a GLP-1 Analogue Act Synergistically to Alleviate Diabetes in Zucker Diabetic Fatty Rats. Diabetes. 2017 07; 66(7):2007-2018.
Score: 0.069
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ß-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. Diabetes Care. 2014 Jun; 37(6):1751-8.
Score: 0.056
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ß-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. J Clin Endocrinol Metab. 2014 Jun; 99(6):1983-92.
Score: 0.056
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What beta-cell defect could lead to hyperproinsulinemia in NIDDM? Some clues from recent advances made in understanding the proinsulin-processing mechanism. Diabetes. 1994 Apr; 43(4):511-7.
Score: 0.056
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Degradation of islet amyloid polypeptide by neprilysin. Diabetologia. 2012 Nov; 55(11):2989-98.
Score: 0.050
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Increased phagocyte-like NADPH oxidase and ROS generation in type 2 diabetic ZDF rat and human islets: role of Rac1-JNK1/2 signaling pathway in mitochondrial dysregulation in the diabetic islet. Diabetes. 2011 Nov; 60(11):2843-52.
Score: 0.047
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The balance between proinsulin biosynthesis and insulin secretion: where can imbalance lead? Diabetes Obes Metab. 2007 Nov; 9 Suppl 2:56-66.
Score: 0.036
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Insulin receptor substrate-2 proteasomal degradation mediated by a mammalian target of rapamycin (mTOR)-induced negative feedback down-regulates protein kinase B-mediated signaling pathway in beta-cells. J Biol Chem. 2005 Jan 21; 280(3):2282-93.
Score: 0.029
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Molecular insights into insulin action and secretion. Eur J Clin Invest. 2002 Jun; 32 Suppl 3:3-13.
Score: 0.024
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Peptide-YY3-36/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic ß-cell function and synergistic activation of discrete hypothalamic and brainstem neuronal circuitries. Mol Metab. 2022 01; 55:101392.
Score: 0.024
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IGF-I and GH post-receptor signaling mechanisms for pancreatic beta-cell replication. J Mol Endocrinol. 2000 Jun; 24(3):303-11.
Score: 0.021
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Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesis. Nat Metab. 2020 05; 2(5):413-431.
Score: 0.021
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Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation. J Clin Invest. 1998 Mar 01; 101(5):1094-101.
Score: 0.018
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The dynamic plasticity of insulin production in ß-cells. Mol Metab. 2017 09; 6(9):958-973.
Score: 0.017
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Increased secretory demand rather than a defect in the proinsulin conversion mechanism causes hyperproinsulinemia in a glucose-infusion rat model of non-insulin-dependent diabetes mellitus. J Clin Invest. 1995 Mar; 95(3):1032-9.
Score: 0.015