Christopher Rhodes to Protein Precursors
This is a "connection" page, showing publications Christopher Rhodes has written about Protein Precursors.
Connection Strength
1.239
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A cis-element in the 5' untranslated region of the preproinsulin mRNA (ppIGE) is required for glucose regulation of proinsulin translation. Cell Metab. 2007 Mar; 5(3):221-7.
Score: 0.286
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Glucose-induced translational control of proinsulin biosynthesis is proportional to preproinsulin mRNA levels in islet beta-cells but not regulated via a positive feedback of secreted insulin. J Biol Chem. 2003 Oct 24; 278(43):42080-90.
Score: 0.224
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Cooperativity between the preproinsulin mRNA untranslated regions is necessary for glucose-stimulated translation. J Biol Chem. 2001 Jun 22; 276(25):22553-8.
Score: 0.190
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Specific co-ordinated regulation of PC3 and PC2 gene expression with that of preproinsulin in insulin-producing beta TC3 cells. Biochem J. 1996 Jan 01; 313 ( Pt 1):259-68.
Score: 0.132
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Preferential cleavage of des-31,32-proinsulin over intact proinsulin by the insulin secretory granule type II endopeptidase. Implication of a favored route for prohormone processing. J Biol Chem. 1992 Nov 15; 267(32):22719-27.
Score: 0.106
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Exendin 4 controls insulin production in rat islet beta cells predominantly by potentiation of glucose-stimulated proinsulin biosynthesis at the translational level. Diabetologia. 2006 Dec; 49(12):2920-9.
Score: 0.070
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Intragranular targeting of syncollin, but not a syncollinGFP chimera, inhibits regulated insulin exocytosis in pancreatic beta-cells. J Endocrinol. 2005 Apr; 185(1):57-67.
Score: 0.063
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Glucagon-like peptide-1 regulates proliferation and apoptosis via activation of protein kinase B in pancreatic INS-1 beta cells. Diabetologia. 2004 Mar; 47(3):478-487.
Score: 0.058
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Protein kinase Czeta activation mediates glucagon-like peptide-1-induced pancreatic beta-cell proliferation. Diabetes. 2001 Oct; 50(10):2237-43.
Score: 0.049
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A Kex2-related endopeptidase activity present in rat liver specifically processes the insulin proreceptor. Biochem J. 1994 Jul 01; 301 ( Pt 1):257-65.
Score: 0.030
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The ratio of mouse insulin I:insulin II does not reflect that of the corresponding preproinsulin mRNAs. Mol Cell Endocrinol. 1992 Aug; 86(3):177-86.
Score: 0.026
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PACE4 is a member of the mammalian propeptidase family that has overlapping but not identical substrate specificity to PACE. Biochemistry. 1993 Nov 02; 32(43):11586-90.
Score: 0.007