Christopher Rhodes to Mice
This is a "connection" page, showing publications Christopher Rhodes has written about Mice.
Connection Strength
1.089
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Pancreatic ß-Cell Adaptive Plasticity in Obesity Increases Insulin Production but Adversely Affects Secretory Function. Diabetes. 2016 Feb; 65(2):438-50.
Score: 0.047
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RNA Sequencing Analysis Detection of a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2015 Aug 01; 192(3):356-66.
Score: 0.047
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Direct autocrine action of insulin on ß-cells: does it make physiological sense? Diabetes. 2013 Jul; 62(7):2157-63.
Score: 0.041
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Islet autoantigens: structure, function, localization, and regulation. Cold Spring Harb Perspect Med. 2012 Aug 01; 2(8).
Score: 0.038
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Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via Ca2+-dependent calcineurin/NFAT signaling in primary pancreatic islet ß-cells. Diabetes. 2011 Nov; 60(11):2892-902.
Score: 0.036
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FoxO feedback control of basal IRS-2 expression in pancreatic ß-cells is distinct from that in hepatocytes. Diabetes. 2011 Nov; 60(11):2883-91.
Score: 0.036
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Iron deficiency in pulmonary arterial hypertension: a potential therapeutic target. Eur Respir J. 2011 Dec; 38(6):1453-60.
Score: 0.035
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Roles for Prlhr/GPR10 and Npffr2/GPR74 in feeding responses to PrRP. Mol Metab. 2025 Feb; 92:102093.
Score: 0.023
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Pancreatic beta-cell growth and survival in the onset of type 2 diabetes: a role for protein kinase B in the Akt? Am J Physiol Endocrinol Metab. 2004 Aug; 287(2):E192-8.
Score: 0.022
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Allele-specific control of rodent and human lncRNA KMT2E-AS1 promotes hypoxic endothelial pathology in pulmonary hypertension. Sci Transl Med. 2024 01 10; 16(729):eadd2029.
Score: 0.021
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SOX17 Enhancer Variants Disrupt Transcription Factor Binding And Enhancer Inactivity Drives Pulmonary Hypertension. Circulation. 2023 05 23; 147(21):1606-1621.
Score: 0.020
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Restoring polyamine levels by supplementation of spermidine modulates hepatic immune landscape in murine model of NASH. Biochim Biophys Acta Mol Basis Dis. 2023 08; 1869(6):166697.
Score: 0.020
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PTPN1 Deficiency Modulates BMPR2 Signaling and Induces Endothelial Dysfunction in Pulmonary Arterial Hypertension. Cells. 2023 01 14; 12(2).
Score: 0.020
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Insulin secretory deficiency and glucose intolerance in Rab3A null mice. J Biol Chem. 2003 Mar 14; 278(11):9715-21.
Score: 0.020
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Pancreatic beta-cell growth and survival--a role in obesity-linked type 2 diabetes? Trends Mol Med. 2002 Aug; 8(8):375-84.
Score: 0.019
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Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life. Nat Commun. 2022 07 27; 13(1):4352.
Score: 0.019
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Molecular insights into insulin action and secretion. Eur J Clin Invest. 2002 Jun; 32 Suppl 3:3-13.
Score: 0.019
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Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain. Elife. 2022 02 17; 11.
Score: 0.018
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Peptide-YY3-36/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic ß-cell function and synergistic activation of discrete hypothalamic and brainstem neuronal circuitries. Mol Metab. 2022 01; 55:101392.
Score: 0.018
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BAd-CRISPR: Inducible gene knockout in interscapular brown adipose tissue of adult mice. J Biol Chem. 2021 12; 297(6):101402.
Score: 0.018
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NTS Prlh overcomes orexigenic stimuli and ameliorates dietary and genetic forms of obesity. Nat Commun. 2021 08 30; 12(1):5175.
Score: 0.018
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A genetic map of the mouse dorsal vagal complex and its role in obesity. Nat Metab. 2021 04; 3(4):530-545.
Score: 0.017
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Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesis. Nat Metab. 2020 05; 2(5):413-431.
Score: 0.016
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A fluorescent timer reporter enables sorting of insulin secretory granules by age. J Biol Chem. 2020 07 03; 295(27):8901-8911.
Score: 0.016
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Leptin receptor-expressing nucleus tractus solitarius neurons suppress food intake independently of GLP1 in mice. JCI Insight. 2020 04 09; 5(7).
Score: 0.016
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Characterization of Signaling Pathways Associated with Pancreatic ß-cell Adaptive Flexibility in Compensation of Obesity-linked Diabetes in db/db Mice. Mol Cell Proteomics. 2020 06; 19(6):971-993.
Score: 0.016
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Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension. Nat Commun. 2020 03 04; 11(1):1185.
Score: 0.016
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Calcitonin Receptor Neurons in the Mouse Nucleus Tractus Solitarius Control Energy Balance via the Non-aversive Suppression of Feeding. Cell Metab. 2020 02 04; 31(2):301-312.e5.
Score: 0.016
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Immunoglobulin-driven Complement Activation Regulates Proinflammatory Remodeling in Pulmonary Hypertension. Am J Respir Crit Care Med. 2020 01 15; 201(2):224-239.
Score: 0.016
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Proteomic Analysis of Restored Insulin Production and Trafficking in Obese Diabetic Mouse Pancreatic Islets Following Euglycemia. J Proteome Res. 2019 09 06; 18(9):3245-3258.
Score: 0.015
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Combined loss of GLP-1R and Y2R does not alter progression of high-fat diet-induced obesity or response to RYGB surgery in mice. Mol Metab. 2019 07; 25:64-72.
Score: 0.015
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Identification of the Novel Tooth-Specific Transcription Factor AmeloD. J Dent Res. 2019 02; 98(2):234-241.
Score: 0.015
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Pancreatic ß-Cell Rest Replenishes Insulin Secretory Capacity and Attenuates Diabetes in an Extreme Model of Obese Type 2 Diabetes. Diabetes. 2019 01; 68(1):131-140.
Score: 0.015
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Essential Role for Hypothalamic Calcitonin Receptor?Expressing Neurons in the Control of Food Intake by Leptin. Endocrinology. 2018 04 01; 159(4):1860-1872.
Score: 0.014
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Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity. Cell Rep. 2017 Sep 26; 20(13):3149-3161.
Score: 0.014
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In Pulmonary Arterial Hypertension, Reduced BMPR2 Promotes Endothelial-to-Mesenchymal Transition via HMGA1 and Its Target Slug. Circulation. 2016 May 03; 133(18):1783-94.
Score: 0.012
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Glucose-regulated translational control of proinsulin biosynthesis with that of the proinsulin endopeptidases PC2 and PC3 in the insulin-producing MIN6 cell line. Diabetes. 1996 Jan; 45(1):37-43.
Score: 0.012
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Specific co-ordinated regulation of PC3 and PC2 gene expression with that of preproinsulin in insulin-producing beta TC3 cells. Biochem J. 1996 Jan 01; 313 ( Pt 1):259-68.
Score: 0.012
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Control of food intake and energy expenditure by Nos1 neurons of the paraventricular hypothalamus. J Neurosci. 2014 Nov 12; 34(46):15306-18.
Score: 0.011
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Leptin-inhibited PBN neurons enhance responses to hypoglycemia in negative energy balance. Nat Neurosci. 2014 Dec; 17(12):1744-1750.
Score: 0.011
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SORCS1 is necessary for normal insulin secretory granule biogenesis in metabolically stressed ß cells. J Clin Invest. 2014 Oct; 124(10):4240-56.
Score: 0.011
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miR-21/DDAH1 pathway regulates pulmonary vascular responses to hypoxia. Biochem J. 2014 Aug 15; 462(1):103-12.
Score: 0.011
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Aberrant chloride intracellular channel 4 expression contributes to endothelial dysfunction in pulmonary arterial hypertension. Circulation. 2014 Apr 29; 129(17):1770-80.
Score: 0.011
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ß1 integrin is a crucial regulator of pancreatic ß-cell expansion. Development. 2013 Aug; 140(16):3360-72.
Score: 0.010
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BMPR-II deficiency elicits pro-proliferative and anti-apoptotic responses through the activation of TGFß-TAK1-MAPK pathways in PAH. Hum Mol Genet. 2012 Jun 01; 21(11):2548-58.
Score: 0.009
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Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance. Cell Metab. 2011 Sep 07; 14(3):313-23.
Score: 0.009
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Glucose and fatty acids synergize to promote B-cell apoptosis through activation of glycogen synthase kinase 3ß independent of JNK activation. PLoS One. 2011 Apr 26; 6(4):e18146.
Score: 0.009
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Leptin-receptor-expressing neurons in the dorsomedial hypothalamus and median preoptic area regulate sympathetic brown adipose tissue circuits. J Neurosci. 2011 Feb 02; 31(5):1873-84.
Score: 0.009
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Mechanism of action of glucagon-like peptide-2 to increase IGF-I mRNA in intestinal subepithelial fibroblasts. Endocrinology. 2011 Feb; 152(2):436-46.
Score: 0.009
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Direct innervation and modulation of orexin neurons by lateral hypothalamic LepRb neurons. J Neurosci. 2010 Aug 25; 30(34):11278-87.
Score: 0.008
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Ventral tegmental area leptin receptor neurons specifically project to and regulate cocaine- and amphetamine-regulated transcript neurons of the extended central amygdala. J Neurosci. 2010 Apr 21; 30(16):5713-23.
Score: 0.008
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A potential role for hypothalamomedullary POMC projections in leptin-induced suppression of food intake. Am J Physiol Regul Integr Comp Physiol. 2010 Mar; 298(3):R720-8.
Score: 0.008
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Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding. Cell Metab. 2009 Aug; 10(2):89-98.
Score: 0.008
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Suppressor of cytokine signalling-3 inhibits Tumor necrosis factor-alpha induced apoptosis and signalling in beta cells. Mol Cell Endocrinol. 2009 Nov 13; 311(1-2):32-8.
Score: 0.008
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Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells. Diabetes. 2009 Sep; 58(9):2048-58.
Score: 0.008
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Direct innervation of GnRH neurons by metabolic- and sexual odorant-sensing leptin receptor neurons in the hypothalamic ventral premammillary nucleus. J Neurosci. 2009 Mar 11; 29(10):3138-47.
Score: 0.008
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Insulin regulates glucagon-like peptide-1 secretion from the enteroendocrine L cell. Endocrinology. 2009 Feb; 150(2):580-91.
Score: 0.007
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Regulated autophagy controls hormone content in secretory-deficient pancreatic endocrine beta-cells. Mol Endocrinol. 2007 Sep; 21(9):2255-69.
Score: 0.007
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Impaired NH2-terminal processing of human proislet amyloid polypeptide by the prohormone convertase PC2 leads to amyloid formation and cell death. Diabetes. 2006 Aug; 55(8):2192-201.
Score: 0.006
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Activation of mammalian target of rapamycin (mTOR) by insulin is associated with stimulation of 4EBP1 binding to dimeric mTOR complex 1. J Biol Chem. 2006 Aug 25; 281(34):24293-303.
Score: 0.006
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Insulin-like growth factor 1 receptor signaling regulates skin development and inhibits skin keratinocyte differentiation. Mol Cell Biol. 2006 Apr; 26(7):2675-87.
Score: 0.006
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Inositol (1,4,5)-trisphosphate dynamics and intracellular calcium oscillations in pancreatic beta-cells. Diabetes. 2005 Nov; 54(11):3073-81.
Score: 0.006
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Effect of interferon and double-stranded RNA on B-cell function in mouse islets of Langerhans. Biochem J. 1985 May 15; 228(1):87-94.
Score: 0.006
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Insulin receptor substrate 2 plays diverse cell-specific roles in the regulation of glucose transport. J Biol Chem. 2005 Apr 15; 280(15):14536-44.
Score: 0.006
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2-5A-dependent endoribonuclease activity and effects of A2'p5'A2'p5'A (2-5A core) in mouse pancreatic islets. FEBS Lett. 1985 Jan 21; 180(1):69-73.
Score: 0.006
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The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species. J Biol Chem. 2005 Feb 11; 280(6):4617-26.
Score: 0.006
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Syncollin inhibits regulated corticotropin secretion from AtT-20 cells through a reduction in the secretory vesicle population. Biochem J. 2004 Jun 15; 380(Pt 3):897-905.
Score: 0.005
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Direct imaging shows that insulin granule exocytosis occurs by complete vesicle fusion. Proc Natl Acad Sci U S A. 2004 Jun 22; 101(25):9266-71.
Score: 0.005
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Role of beta-cell prohormone convertase (PC)1/3 in processing of pro-islet amyloid polypeptide. Diabetes. 2004 Jan; 53(1):141-8.
Score: 0.005
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Signal transducer and activator of transcription 5 activation is sufficient to drive transcriptional induction of cyclin D2 gene and proliferation of rat pancreatic beta-cells. Mol Endocrinol. 2003 May; 17(5):945-58.
Score: 0.005
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The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti. Hum Mol Genet. 2001 Mar 01; 10(5):507-12.
Score: 0.004
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Acute stimulation with long chain acyl-CoA enhances exocytosis in insulin-secreting cells (HIT T-15 and NMRI beta-cells). J Biol Chem. 2000 Mar 31; 275(13):9363-8.
Score: 0.004
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Cysteine string protein (CSP) is an insulin secretory granule-associated protein regulating beta-cell exocytosis. EMBO J. 1998 Sep 01; 17(17):5048-58.
Score: 0.004
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Insulin-stimulated translocation of GLUT4 glucose transporters requires SNARE-complex proteins. Proc Natl Acad Sci U S A. 1996 Dec 24; 93(26):15169-73.
Score: 0.003
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Insulin-secreting non-islet cells are resistant to autoimmune destruction. Proc Natl Acad Sci U S A. 1996 Aug 06; 93(16):8595-600.
Score: 0.003
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The c-propeptide of type II procollagen binds to the enhancer region of the type II procollagen gene and regulates its transcription. Ann N Y Acad Sci. 1996 Jun 08; 785:307-8.
Score: 0.003
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PKC-dependent stimulation of exocytosis by sulfonylureas in pancreatic beta cells. Science. 1996 Feb 09; 271(5250):813-5.
Score: 0.003
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A Kex2-related endopeptidase activity present in rat liver specifically processes the insulin proreceptor. Biochem J. 1994 Jul 01; 301 ( Pt 1):257-65.
Score: 0.003
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Ca(2+)-regulated serine protease associated with the nuclear scaffold. Cell Growth Differ. 1992 Nov; 3(11):827-38.
Score: 0.002
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The ratio of mouse insulin I:insulin II does not reflect that of the corresponding preproinsulin mRNAs. Mol Cell Endocrinol. 1992 Aug; 86(3):177-86.
Score: 0.002
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Regulation of the biosynthesis of insulin-secretory-granule proteins. Co-ordinate translational control is exerted on some, but not all, granule matrix constituents. Biochem J. 1989 Jan 15; 257(2):431-7.
Score: 0.002
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Long-term biochemical changes in the islets of Langerhans in mice following infection with encephalomyocarditis virus. Diabetologia. 1984 May; 26(5):370-4.
Score: 0.001