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Connection

Christopher Rhodes to Insulin-Secreting Cells

This is a "connection" page, showing publications Christopher Rhodes has written about Insulin-Secreting Cells.
Connection Strength

5.381
  1. GLP-1R/GCGR dual agonism dissipates hepatic steatosis to restore insulin sensitivity and rescue pancreatic ß-cell function in obese male mice. Nat Commun. 2025 May 21; 16(1):4714.
    View in: PubMed
    Score: 0.700
  2. ß-Cell Control of Insulin Production During Starvation-Refeeding in Male Rats. Endocrinology. 2018 Feb 01; 159(2):895-906.
    View in: PubMed
    Score: 0.422
  3. Pancreatic ß-Cell Adaptive Plasticity in Obesity Increases Insulin Production but Adversely Affects Secretory Function. Diabetes. 2016 Feb; 65(2):438-50.
    View in: PubMed
    Score: 0.357
  4. Direct autocrine action of insulin on ß-cells: does it make physiological sense? Diabetes. 2013 Jul; 62(7):2157-63.
    View in: PubMed
    Score: 0.307
  5. Islet autoantigens: structure, function, localization, and regulation. Cold Spring Harb Perspect Med. 2012 Aug 01; 2(8).
    View in: PubMed
    Score: 0.288
  6. Formation of a human ß-cell population within pancreatic islets is set early in life. J Clin Endocrinol Metab. 2012 Sep; 97(9):3197-206.
    View in: PubMed
    Score: 0.287
  7. Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via Ca2+-dependent calcineurin/NFAT signaling in primary pancreatic islet ß-cells. Diabetes. 2011 Nov; 60(11):2892-902.
    View in: PubMed
    Score: 0.272
  8. FoxO feedback control of basal IRS-2 expression in pancreatic ß-cells is distinct from that in hepatocytes. Diabetes. 2011 Nov; 60(11):2883-91.
    View in: PubMed
    Score: 0.272
  9. How does type 1 diabetes develop?: the notion of homicide or ß-cell suicide revisited. Diabetes. 2011 May; 60(5):1370-9.
    View in: PubMed
    Score: 0.264
  10. Beta-cell regeneration: epithelial mesenchymal transition pre-EMTpted by lineage tracing? Diabetes. 2007 Jan; 56(1):281-2.
    View in: PubMed
    Score: 0.196
  11. Exendin 4 controls insulin production in rat islet beta cells predominantly by potentiation of glucose-stimulated proinsulin biosynthesis at the translational level. Diabetologia. 2006 Dec; 49(12):2920-9.
    View in: PubMed
    Score: 0.193
  12. 10th EASD/JDRF Oxford Workshop. What is a beta-cell and can we improve it? Diabetologia. 2005 Nov; 48(11):R93-101.
    View in: PubMed
    Score: 0.181
  13. Characterization of Signaling Pathways Associated with Pancreatic ß-cell Adaptive Flexibility in Compensation of Obesity-linked Diabetes in db/db Mice. Mol Cell Proteomics. 2020 06; 19(6):971-993.
    View in: PubMed
    Score: 0.123
  14. Pancreatic ß-Cell Rest Replenishes Insulin Secretory Capacity and Attenuates Diabetes in an Extreme Model of Obese Type 2 Diabetes. Diabetes. 2019 01; 68(1):131-140.
    View in: PubMed
    Score: 0.111
  15. The dynamic plasticity of insulin production in ß-cells. Mol Metab. 2017 09; 6(9):958-973.
    View in: PubMed
    Score: 0.100
  16. Neurturin and a GLP-1 Analogue Act Synergistically to Alleviate Diabetes in Zucker Diabetic Fatty Rats. Diabetes. 2017 07; 66(7):2007-2018.
    View in: PubMed
    Score: 0.100
  17. Monomethylated-adenines potentiate glucose-induced insulin production and secretion via inhibition of phosphodiesterase activity in rat pancreatic islets. Islets. 2015; 7(2):e1073435.
    View in: PubMed
    Score: 0.090
  18. SORCS1 is necessary for normal insulin secretory granule biogenesis in metabolically stressed ß cells. J Clin Invest. 2014 Oct; 124(10):4240-56.
    View in: PubMed
    Score: 0.083
  19. ß-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. Diabetes Care. 2014 Jun; 37(6):1751-8.
    View in: PubMed
    Score: 0.081
  20. ß-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. J Clin Endocrinol Metab. 2014 Jun; 99(6):1983-92.
    View in: PubMed
    Score: 0.081
  21. ß1 integrin is a crucial regulator of pancreatic ß-cell expansion. Development. 2013 Aug; 140(16):3360-72.
    View in: PubMed
    Score: 0.077
  22. Degradation of islet amyloid polypeptide by neprilysin. Diabetologia. 2012 Nov; 55(11):2989-98.
    View in: PubMed
    Score: 0.072
  23. Glucose and fatty acids synergize to promote B-cell apoptosis through activation of glycogen synthase kinase 3ß independent of JNK activation. PLoS One. 2011 Apr 26; 6(4):e18146.
    View in: PubMed
    Score: 0.066
  24. Arf nucleotide binding site opener [ARNO] promotes sequential activation of Arf6, Cdc42 and Rac1 and insulin secretion in INS 832/13 ß-cells and rat islets. Biochem Pharmacol. 2011 Apr 15; 81(8):1016-27.
    View in: PubMed
    Score: 0.065
  25. Glucolipotoxicity age-dependently impairs beta cell function in rats despite a marked increase in beta cell mass. Diabetologia. 2010 Nov; 53(11):2369-79.
    View in: PubMed
    Score: 0.063
  26. Protein farnesylation-dependent Raf/extracellular signal-related kinase signaling links to cytoskeletal remodeling to facilitate glucose-induced insulin secretion in pancreatic beta-cells. Diabetes. 2010 Apr; 59(4):967-77.
    View in: PubMed
    Score: 0.060
  27. AMP-activated protein kinase attenuates nitric oxide-induced beta-cell death. J Biol Chem. 2010 Jan 29; 285(5):3191-200.
    View in: PubMed
    Score: 0.060
  28. Suppressor of cytokine signalling-3 inhibits Tumor necrosis factor-alpha induced apoptosis and signalling in beta cells. Mol Cell Endocrinol. 2009 Nov 13; 311(1-2):32-8.
    View in: PubMed
    Score: 0.059
  29. Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells. Diabetes. 2009 Sep; 58(9):2048-58.
    View in: PubMed
    Score: 0.058
  30. The balance between proinsulin biosynthesis and insulin secretion: where can imbalance lead? Diabetes Obes Metab. 2007 Nov; 9 Suppl 2:56-66.
    View in: PubMed
    Score: 0.052
  31. Regulated autophagy controls hormone content in secretory-deficient pancreatic endocrine beta-cells. Mol Endocrinol. 2007 Sep; 21(9):2255-69.
    View in: PubMed
    Score: 0.051
  32. Impact of defined matrix interactions on insulin production by cultured human beta-cells: effect on insulin content, secretion, and gene transcription. Diabetes. 2006 Oct; 55(10):2723-9.
    View in: PubMed
    Score: 0.048
  33. The mitochondrial citrate/isocitrate carrier plays a regulatory role in glucose-stimulated insulin secretion. J Biol Chem. 2006 Nov 24; 281(47):35624-32.
    View in: PubMed
    Score: 0.048
  34. Peptide-YY3-36/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic ß-cell function and synergistic activation of discrete hypothalamic and brainstem neuronal circuitries. Mol Metab. 2022 01; 55:101392.
    View in: PubMed
    Score: 0.034
  35. A fluorescent timer reporter enables sorting of insulin secretory granules by age. J Biol Chem. 2020 07 03; 295(27):8901-8911.
    View in: PubMed
    Score: 0.031
  36. Proteomic Analysis of Restored Insulin Production and Trafficking in Obese Diabetic Mouse Pancreatic Islets Following Euglycemia. J Proteome Res. 2019 09 06; 18(9):3245-3258.
    View in: PubMed
    Score: 0.029
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.