Christopher Rhodes to Glucose
This is a "connection" page, showing publications Christopher Rhodes has written about Glucose.
Connection Strength
4.134
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The Brain-to-Pancreatic Islet Neuronal Map Reveals Differential Glucose Regulation From Distinct Hypothalamic Regions. Diabetes. 2016 09; 65(9):2711-23.
Score: 0.449
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Translational control of glucose-induced islet amyloid polypeptide production in pancreatic islets. Endocrinology. 2012 May; 153(5):2082-7.
Score: 0.338
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A cis-element in the 5' untranslated region of the preproinsulin mRNA (ppIGE) is required for glucose regulation of proinsulin translation. Cell Metab. 2007 Mar; 5(3):221-7.
Score: 0.239
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Glucose-induced translational control of proinsulin biosynthesis is proportional to preproinsulin mRNA levels in islet beta-cells but not regulated via a positive feedback of secreted insulin. J Biol Chem. 2003 Oct 24; 278(43):42080-90.
Score: 0.187
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Differential activation mechanisms of Erk-1/2 and p70(S6K) by glucose in pancreatic beta-cells. Diabetes. 2003 Apr; 52(4):974-83.
Score: 0.182
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Succinate is a preferential metabolic stimulus-coupling signal for glucose-induced proinsulin biosynthesis translation. Diabetes. 2002 Aug; 51(8):2496-504.
Score: 0.174
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Molecular insights into insulin action and secretion. Eur J Clin Invest. 2002 Jun; 32 Suppl 3:3-13.
Score: 0.172
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Cooperativity between the preproinsulin mRNA untranslated regions is necessary for glucose-stimulated translation. J Biol Chem. 2001 Jun 22; 276(25):22553-8.
Score: 0.159
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Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1). J Biol Chem. 2001 Jun 15; 276(24):21110-20.
Score: 0.158
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Inhibition of upper small intestinal mTOR lowers plasma glucose levels by inhibiting glucose production. Nat Commun. 2019 02 12; 10(1):714.
Score: 0.137
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Glucose-regulated translational control of proinsulin biosynthesis with that of the proinsulin endopeptidases PC2 and PC3 in the insulin-producing MIN6 cell line. Diabetes. 1996 Jan; 45(1):37-43.
Score: 0.110
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Glucose and fatty acids synergize to promote B-cell apoptosis through activation of glycogen synthase kinase 3ß independent of JNK activation. PLoS One. 2011 Apr 26; 6(4):e18146.
Score: 0.080
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Glucolipotoxicity age-dependently impairs beta cell function in rats despite a marked increase in beta cell mass. Diabetologia. 2010 Nov; 53(11):2369-79.
Score: 0.075
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Glycogen synthase kinase 3 beta mediates high glucose-induced ubiquitination and proteasome degradation of insulin receptor substrate 1. J Endocrinol. 2010 Aug; 206(2):171-81.
Score: 0.075
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Protein farnesylation-dependent Raf/extracellular signal-related kinase signaling links to cytoskeletal remodeling to facilitate glucose-induced insulin secretion in pancreatic beta-cells. Diabetes. 2010 Apr; 59(4):967-77.
Score: 0.073
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Glucose stimulates the biosynthesis of rat I and II insulin to an equal extent in isolated pancreatic islets. FEBS Lett. 1987 May 04; 215(1):179-82.
Score: 0.060
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Exendin 4 controls insulin production in rat islet beta cells predominantly by potentiation of glucose-stimulated proinsulin biosynthesis at the translational level. Diabetologia. 2006 Dec; 49(12):2920-9.
Score: 0.058
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The mitochondrial citrate/isocitrate carrier plays a regulatory role in glucose-stimulated insulin secretion. J Biol Chem. 2006 Nov 24; 281(47):35624-32.
Score: 0.058
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Specific regulation of IRS-2 expression by glucose in rat primary pancreatic islet beta-cells. J Biol Chem. 2006 Jun 09; 281(23):15884-92.
Score: 0.056
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Effects of glucose and D-3-hydroxybutyrate on human pancreatic islet cell function. Clin Sci (Lond). 1985 May; 68(5):567-72.
Score: 0.053
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Intragranular targeting of syncollin, but not a syncollinGFP chimera, inhibits regulated insulin exocytosis in pancreatic beta-cells. J Endocrinol. 2005 Apr; 185(1):57-67.
Score: 0.052
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Insulin receptor substrate 2 plays diverse cell-specific roles in the regulation of glucose transport. J Biol Chem. 2005 Apr 15; 280(15):14536-44.
Score: 0.052
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Insulin receptor substrate-2 proteasomal degradation mediated by a mammalian target of rapamycin (mTOR)-induced negative feedback down-regulates protein kinase B-mediated signaling pathway in beta-cells. J Biol Chem. 2005 Jan 21; 280(3):2282-93.
Score: 0.051
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Glucagon-like peptide-1 prevents beta cell glucolipotoxicity. Diabetologia. 2004 May; 47(5):806-15.
Score: 0.049
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Diazoxide attenuates glucose-induced defects in first-phase insulin release and pulsatile insulin secretion in human islets. Endocrinology. 2003 Aug; 144(8):3399-405.
Score: 0.047
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IRS-3 inhibits IRS-2-mediated signaling in pancreatic beta-cells. Mol Cell Endocrinol. 2003 Jun 30; 204(1-2):85-99.
Score: 0.046
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Insulin secretory deficiency and glucose intolerance in Rab3A null mice. J Biol Chem. 2003 Mar 14; 278(11):9715-21.
Score: 0.045
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Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1). J Biol Chem. 2002 Dec 20; 277(51):49676-84.
Score: 0.044
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Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation. Diabetes. 2002 Apr; 51(4):966-76.
Score: 0.042
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A low-affinity Ca2+-dependent association of calmodulin with the Rab3A effector domain inversely correlates with insulin exocytosis. Diabetes. 2001 Sep; 50(9):2029-39.
Score: 0.041
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Glycerol-stimulated proinsulin biosynthesis in isolated pancreatic rat islets via adenoviral-induced expression of glycerol kinase is mediated via mitochondrial metabolism. Diabetes. 2001 Aug; 50(8):1791-8.
Score: 0.041
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Free fatty acid-induced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic acid synthesis in the pancreatic beta-cell line INS-1. Endocrinology. 2001 Jan; 142(1):229-40.
Score: 0.039
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Induction of endothelin-1 expression by glucose: an effect of protein kinase C activation. Diabetes. 2000 Jul; 49(7):1239-48.
Score: 0.038
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IGF-I and GH post-receptor signaling mechanisms for pancreatic beta-cell replication. J Mol Endocrinol. 2000 Jun; 24(3):303-11.
Score: 0.037
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A fluorescent timer reporter enables sorting of insulin secretory granules by age. J Biol Chem. 2020 07 03; 295(27):8901-8911.
Score: 0.037
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Characterization of Signaling Pathways Associated with Pancreatic ß-cell Adaptive Flexibility in Compensation of Obesity-linked Diabetes in db/db Mice. Mol Cell Proteomics. 2020 06; 19(6):971-993.
Score: 0.037
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Stimulation of pancreatic beta-cell proliferation by growth hormone is glucose-dependent: signal transduction via janus kinase 2 (JAK2)/signal transducer and activator of transcription 5 (STAT5) with no crosstalk to insulin receptor substrate-mediated mitogenic signalling. Biochem J. 1999 Dec 15; 344 Pt 3:649-58.
Score: 0.036
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Proteomic Analysis of Restored Insulin Production and Trafficking in Obese Diabetic Mouse Pancreatic Islets Following Euglycemia. J Proteome Res. 2019 09 06; 18(9):3245-3258.
Score: 0.035
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Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways. J Clin Invest. 1999 Jan; 103(2):185-95.
Score: 0.034
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Pancreatic ß-Cell Rest Replenishes Insulin Secretory Capacity and Attenuates Diabetes in an Extreme Model of Obese Type 2 Diabetes. Diabetes. 2019 01; 68(1):131-140.
Score: 0.033
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Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells. J Biol Chem. 1998 Jul 10; 273(28):17771-9.
Score: 0.033
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A distinct difference in the metabolic stimulus-response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moieties. Biochem J. 1998 Apr 15; 331 ( Pt 2):553-61.
Score: 0.032
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Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation. J Clin Invest. 1998 Mar 01; 101(5):1094-101.
Score: 0.032
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The dynamic plasticity of insulin production in ß-cells. Mol Metab. 2017 09; 6(9):958-973.
Score: 0.030
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Specific co-ordinated regulation of PC3 and PC2 gene expression with that of preproinsulin in insulin-producing beta TC3 cells. Biochem J. 1996 Jan 01; 313 ( Pt 1):259-68.
Score: 0.028
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Monomethylated-adenines potentiate glucose-induced insulin production and secretion via inhibition of phosphodiesterase activity in rat pancreatic islets. Islets. 2015; 7(2):e1073435.
Score: 0.027
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SORCS1 is necessary for normal insulin secretory granule biogenesis in metabolically stressed ß cells. J Clin Invest. 2014 Oct; 124(10):4240-56.
Score: 0.025
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The biosynthesis of the subtilisin-related proprotein convertase PC3, but no that of the PC2 convertase, is regulated by glucose in parallel to proinsulin biosynthesis in rat pancreatic islets. J Biol Chem. 1993 Feb 25; 268(6):4276-80.
Score: 0.023
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Arf nucleotide binding site opener [ARNO] promotes sequential activation of Arf6, Cdc42 and Rac1 and insulin secretion in INS 832/13 ß-cells and rat islets. Biochem Pharmacol. 2011 Apr 15; 81(8):1016-27.
Score: 0.020
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Hypothalamic leptin signaling regulates hepatic insulin sensitivity via a neurocircuit involving the vagus nerve. Endocrinology. 2009 Oct; 150(10):4502-11.
Score: 0.018
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Newly synthesized proinsulin/insulin and stored insulin are released from pancreatic B cells predominantly via a regulated, rather than a constitutive, pathway. J Cell Biol. 1987 Jul; 105(1):145-53.
Score: 0.015
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Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons. Cell Metab. 2005 Dec; 2(6):411-20.
Score: 0.014
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Effect of interferon and double-stranded RNA on B-cell function in mouse islets of Langerhans. Biochem J. 1985 May 15; 228(1):87-94.
Score: 0.013
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2-5A-dependent endoribonuclease activity and effects of A2'p5'A2'p5'A (2-5A core) in mouse pancreatic islets. FEBS Lett. 1985 Jan 21; 180(1):69-73.
Score: 0.013
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Effect of human lymphoblastoid interferon on insulin synthesis and secretion in isolated human pancreatic islets. Diabetologia. 1984 Dec; 27(6):601-3.
Score: 0.013
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The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species. J Biol Chem. 2005 Feb 11; 280(6):4617-26.
Score: 0.013
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A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli. Diabetes. 2004 Apr; 53(4):1007-19.
Score: 0.012
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Palmitate inhibition of insulin gene expression is mediated at the transcriptional level via ceramide synthesis. J Biol Chem. 2003 Aug 08; 278(32):30015-21.
Score: 0.012
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Interaction of the Ras-related protein associated with diabetes rad and the putative tumor metastasis suppressor NM23 provides a novel mechanism of GTPase regulation. Proc Natl Acad Sci U S A. 1999 Dec 21; 96(26):14911-8.
Score: 0.009
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Changes in cytoplasmic ATP concentration parallels changes in ATP-regulated K+-channel activity in insulin-secreting cells. FEBS Lett. 1998 Dec 11; 441(1):97-102.
Score: 0.008
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Increased secretory demand rather than a defect in the proinsulin conversion mechanism causes hyperproinsulinemia in a glucose-infusion rat model of non-insulin-dependent diabetes mellitus. J Clin Invest. 1995 Mar; 95(3):1032-9.
Score: 0.006
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The ratio of mouse insulin I:insulin II does not reflect that of the corresponding preproinsulin mRNAs. Mol Cell Endocrinol. 1992 Aug; 86(3):177-86.
Score: 0.005
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Co-secretion of carboxypeptidase H and insulin from isolated rat islets of Langerhans. Biochem J. 1989 Dec 01; 264(2):503-8.
Score: 0.005